{"id":7409,"date":"2021-02-22T06:39:31","date_gmt":"2021-02-22T06:39:31","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7409"},"modified":"2021-05-25T11:08:44","modified_gmt":"2021-05-25T11:08:44","slug":"detremin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/detremin\/","title":{"rendered":"Detremin &#8211; Cholecalciferol uses, dose and side effects"},"content":{"rendered":"\n<p> 20,000 IU \/ ml\u00a0oral drops, solution\u00a0<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tridepos\/\">cholecalciferol<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Detremin is and what it is used for<\/h2>\n\n\n\n<p>Determine contains cholecalciferol (vitamin D&nbsp;<sub>3<\/sub>&nbsp;).&nbsp;It is used to treat vitamin D deficiency in, for example, the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>osteoporosis;&nbsp;then in combination with&nbsp;calcium&nbsp;and other treatment<\/li><li>secondary&nbsp;hyperparathyroidism&nbsp;(when low levels of&nbsp;calcium&nbsp;in the blood lead to excessive secretion of parathyroid hormones along with enlargement of the parathyroid gland).<\/li><\/ul>\n\n\n\n<p>Determine is also used to prevent and treat vitamin D deficiency in people who have difficulty absorbing vitamin D.<br><\/p>\n\n\n\n<p>Cholecalciferol contained in Detremin may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Determine<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Determine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to vitamin D&nbsp;<sub>3<\/sub>&nbsp;&nbsp;or any of the other ingredients of this medicine (see section 6)<\/li><li>if you have&nbsp;hypercalcemia&nbsp;(too high levels of&nbsp;calcium&nbsp;in the blood)<\/li><li>if you have hypervitaminosis D (too high levels of vitamin D in your blood).<\/li><\/ul>\n\n\n\n<p>Do not take Detremin with&nbsp;calcium&nbsp;if you have severe kidney function.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Do not take more Detremin than the&nbsp;dose&nbsp;prescribed&nbsp;by your&nbsp;doctor, as it may lead to overdose.&nbsp;When using Detremin, do not use other products that contain vitamin D at the same time, in addition to those prescribed by your doctor.<br><\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse before taking Detremin:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have had&nbsp;kidney stones<\/li><li>if you have impaired kidney function<\/li><li>if you have&nbsp;sarcoidosis&nbsp;(an&nbsp;inflammatory&nbsp;connective tissue disease that mainly affects the lungs) or any other&nbsp;chronic&nbsp;disease that leads to&nbsp;inflammation&nbsp;of the connective tissue.<\/li><\/ul>\n\n\n\n<p>If you have increased levels of&nbsp;phosphate&nbsp;in your blood, your doctor may&nbsp;prescribe&nbsp;a drug that binds&nbsp;phosphate&nbsp;along with Detremin.&nbsp;Ask your doctor for advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Detremin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.&nbsp;This is especially important if you are using:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>phenytoin&nbsp;(for&nbsp;epilepsy&nbsp;),&nbsp;barbiturates&nbsp;(sleeping pills or sedatives)<\/li><li>rifampicin or&nbsp;isoniazid&nbsp;(for&nbsp;tuberculosis&nbsp;)<\/li><li>cardiac glycosides<\/li><li>diuretics type diuretics (such as&nbsp;hydrochlorothiazide&nbsp;and bendroflumethiazide, drugs for high&nbsp;blood pressure&nbsp;)<\/li><li>tablets containing aluminum (against heartburn)<\/li><li>other products containing vitamin D.<\/li><li>weight loss drugs (eg orlistat and cholestyramine).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Detremin with food and drink<\/h2>\n\n\n\n<p>Detremin can be taken independently of meals.&nbsp;To make it easier to take the drops, you can mix them with food or drink.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Detremin can be used during pregnancy in case of vitamin D deficiency.<br><\/p>\n\n\n\n<p>Detremin can be used during breast-feeding.&nbsp;Vitamin&nbsp;D and its breakdown products are transferred to breast milk.&nbsp;Contact your doctor or midwife if you have any questions about this.<\/p>\n\n\n\n<p>There is no information on the effect of Detremin on&nbsp;fertility.&nbsp;However, normal levels of&nbsp;vitamin&nbsp;D are not expected to hurt&nbsp;fertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>The effect on the ability to drive or use machines has not been studied.&nbsp;Detremin has no known&nbsp;side effects&nbsp;that are thought to affect the ability to drive or use machines.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Detremin<\/h2>\n\n\n\n<p>Always use Detremin exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The dose&nbsp;you receive depends on why you are receiving Detremin and on the level of vitamin D in your blood.&nbsp;It is therefore important that you always take the&nbsp;dose&nbsp;that your doctor has prescribed for you, even if you know someone else who has been&nbsp;prescribed&nbsp;a much higher&nbsp;dose.&nbsp;The usual&nbsp;dose&nbsp;is between 1 drop and 5 drops daily or between 7 drops and 35 drops a week.&nbsp;If you have difficulty taking&nbsp;vitamin&nbsp;D, your doctor may&nbsp;prescribe&nbsp;a higher&nbsp;dose, up to 12 drops daily or 84 drops weekly.&nbsp;Follow your doctor&#8217;s instructions.&nbsp;<br><\/p>\n\n\n\n<p>Detremin can be taken independently of meals.&nbsp;Slowly turn the bottle straight up and down to allow air to enter the bottle.&nbsp;See the picture below:<br><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100227000082#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Renapharma\/Media\/Bild1.jpg\" alt=\"Hold the bottle still, straight up and down.  It may take about 10 seconds for the first drop.  The subsequent drops come slightly faster.\"\/><\/a><\/figure>\n\n\n\n<p>It may take a few seconds for the first drop to come.&nbsp;The subsequent drops come slightly faster.&nbsp;Feel free to take the drops with the help of a spoon.&nbsp;Make sure you swallow the full&nbsp;dose&nbsp;one.<br><\/p>\n\n\n\n<p>If you use Detremin for a long time, your doctor may want to take regular blood tests to check that the treatment is working as well as possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Detremin than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Detremin<\/h2>\n\n\n\n<p>Skip the missed&nbsp;dose&nbsp;one and then take the following&nbsp;dose&nbsp;as usual.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Detremin can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>The following symptoms have been observed after consuming products containing vitamin D&nbsp;<sub>3<\/sub>&nbsp;: too high levels of&nbsp;calcium&nbsp;in the blood and urine, constipation, flatulence, nausea, abdominal pain, diarrhea and&nbsp;hypersensitivity reactions&nbsp;such as&nbsp;itching&nbsp;, rash or&nbsp;hives&nbsp;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Detremin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Store the dropper bottle in the outer carton.&nbsp;Sensitive to light.<\/li><li>Keep out of sight and reach of children.<\/li><li>The contents of the bottle should be used within 6 months of first opening the bottle.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and bottle after \u201cEXP\u201d.&nbsp;respectively &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Do not use Detremin if you notice that the contents of the bottle are cloudy.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is cholecalciferol (vitamin D&nbsp;<sub>3<\/sub>&nbsp;).&nbsp;1 ml of solution (approximately 25 drops) contains 0.5 mg of cholecalciferol, equivalent to 20,000 IU of vitamin D&nbsp;<sub>3<\/sub>&nbsp;.<\/li><li>1 drop contains 20 micrograms of cholecalciferol, equivalent to 800 IU of&nbsp;vitamin&nbsp;<sub>3<\/sub>.<\/li><li>The other ingredients are&nbsp;medium-chain triglycerides.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Detremin is a clear, slightly yellowish,&nbsp;viscous&nbsp;solution.&nbsp;Each carton contains a brown glass bottle with a colorless drip insert and white screw cap.&nbsp;The bottle contains 3.6 ml solution (90 drops of 800 IU&nbsp;vitamin&nbsp;D&nbsp;<sub>3<\/sub>&nbsp;) or 10 ml solution (250 drops of 800 IU&nbsp;vitamin&nbsp;D&nbsp;<sub>3<\/sub>&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Holder of approval for sale:&nbsp;<br>Renapharma AB&nbsp;<br>Riddargatan 16&nbsp;<br>114 51 Stockholm&nbsp;<br>Tel: 018 7001140&nbsp;<br>e-mail: info@renapharma.se<br><\/p>\n\n\n\n<p>Manufacturer<br><\/p>\n\n\n\n<p>NextPharma SAS, 17 route de Meulan, 78520 Limay, France<br><\/p>\n\n\n\n<p><strong>This medicine is authorized in the European Economic Area under the names:<\/strong>&nbsp;<br>Denmark, Finland, Norway: Detremin<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Determine contains cholecalciferol (vitamin D 3 ). It is used to treat vitamin D deficiency in, for example, the following conditions:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[4916,4925,4918,5752,5755,5754,2212,4812,5753],"class_list":["post-7409","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-cholecalciferol","tag-cholecalciferol-oral-drops","tag-cholecalciferol-side-effects","tag-detremin","tag-detremin-oral-drops","tag-detremin-side-effects","tag-medicine","tag-oral-drops","tag-what-is-detremin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7409","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7409"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7409\/revisions"}],"predecessor-version":[{"id":11057,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7409\/revisions\/11057"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}