{"id":7407,"date":"2021-02-22T06:37:35","date_gmt":"2021-02-22T06:37:35","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7407"},"modified":"2021-05-25T11:11:48","modified_gmt":"2021-05-25T11:11:48","slug":"desonix","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/desonix\/","title":{"rendered":"Desonix &#8211; Budesonide uses, dose and side effects"},"content":{"rendered":"\n<p> 32 micrograms\/dose\u00a0nasal spray,\u00a0suspension\u00a0<br>budesonide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Desonix is \u200b\u200band what it is used for<\/h2>\n\n\n\n<p>Desonix contains budesonide, a&nbsp;synthetic&nbsp;corticosteroid.&nbsp;Corticosteroids&nbsp;are a group of drugs that work by fighting&nbsp;inflammation.&nbsp;Desonix is \u200b\u200bused for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Runny nose, nasal congestion, sneezing, and\/or&nbsp;itching&nbsp;in the nose caused by&nbsp;allergies&nbsp;to e.g.&nbsp;pollen (so-called hay fever).<\/li><\/ul>\n\n\n\n<p>Budesonide contained in Desonix may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Desonix<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Desonix<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to budesonide or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Talk to your doctor or pharmacist before taking Desonix<\/li><li>if you have been taking this medicine regularly for a long time.&nbsp;Your doctor will want to examine the inside of your nose at least every six months.<\/li><li>if you have taken larger amounts of this medicine than the recommended&nbsp;doses.&nbsp;Your doctor may&nbsp;prescribe&nbsp;cortisone tablets during periods of stress (eg if you have an&nbsp;infection&nbsp;) or before surgery.<\/li><li>if you have a sore nose.<\/li><li>if you have contagious blisters on your lips (cold sores), in your nose,e or around your eyes.<\/li><li>if you get nosebleeds.<\/li><li>if you have had surgery on your nose or have any other damage to your nose that has not healed completely.<\/li><li>if you have a bacterial&nbsp;infection, a viral infection, or a fungal infection in your nose: You should only use Desonix if you have also been prescribed medicine for&nbsp;infection.<\/li><li>if you have liver problems because the amount of budesonide can be stored in your body.&nbsp;Your doctor may need to check your liver and as a result, reduce the&nbsp;dose&nbsp;one.<\/li><li>if you have switched from another dosage form to nasal spray and have problems with adrenal function.<\/li><li>if your doctor has told you that you have a respiratory infection or pulmonary tuberculosis.&nbsp;This is an&nbsp;infection&nbsp;that can affect the lungs.<\/li><li>In rare cases,&nbsp;corticosteroids&nbsp;given locally can cause&nbsp;side effects&nbsp;that affect the whole body.&nbsp;These are likely to depend on the&nbsp;dose, duration of treatment, adjunctive or previous&nbsp;corticosteroid therapy,&nbsp;and individual factors.&nbsp;Corticosteroids&nbsp;given through the nose can cause the following side effects: Cushing&#8217;s syndrome, cushingoid symptoms, impaired adrenal function, growth retardation in children and adolescents, cloudy eye lens (cataracts), and increased pressure in the eye (&nbsp;glaucoma&nbsp;).&nbsp;In rarer cases, there are psychological or behavioral disorders, including&nbsp;psychomotor&nbsp;hyperactivity, sleep disorders, anxiety, depression, or aggression (especially in children).<\/li><\/ul>\n\n\n\n<p>Contact your doctor if you experience blurred vision or other visual disturbances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The long-term effects of children taking&nbsp;corticosteroids&nbsp;locally (such as in the nose) are not fully understood.&nbsp;If you are a child and take high&nbsp;doses&nbsp;of this medicine for a long period of time, your doctor will check your duration regularly.&nbsp;<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Desonix<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<br><\/p>\n\n\n\n<p>Be sure to tell your doctor if you are taking:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ketoconazole, a drug used to treat fungal infections, such as cod.<\/li><li>troleandomycin, a medicine to treat a bacterial&nbsp;infection&nbsp;you<\/li><li>itraconazole, a medicine used to treat fungal infections<\/li><li>ciclosporin, an immunosuppressive agent used in e.g.&nbsp;transplants<\/li><li>and Ethinyl estradiol, a contraceptive.<\/li><\/ul>\n\n\n\n<p>These medicines may also increase the concentration of budesonide in your body.<br><\/p>\n\n\n\n<p>Some medicines may increase the effects of Desonix and your doctor may want to monitor you closely if you are taking these medicines (eg some medicines for HIV: ritonavir, cobicistat).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>You should not use Desonix if you are pregnant unless you have discussed this with your doctor.<br><\/p>\n\n\n\n<p>Budesonide passes into breast milk, but normal&nbsp;doses&nbsp;probably do not affect infants.&nbsp;Breastfeeding mothers can use Desonix, but only if the doctor has decided that the benefits to the mother outweigh the risks to the breastfed baby.&nbsp;Tell your doctor immediately if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>This medicine may cause blurred vision.&nbsp;If this happens to you, do not drive or use any machinery.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Desonix contains potassium sorbate<\/h2>\n\n\n\n<p>Potassium sorbate is an ingredient in Desonix.&nbsp;It may irritate the skin or mucous membranes (eg contact dermatitis).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Desonix<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Desonix is \u200b\u200bintended for&nbsp;<strong>use in the nose<\/strong>.&nbsp;It should be sprayed into the nostrils as described below.<br><\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>Dose&nbsp;one should be adjusted to suit you.&nbsp;Use the lowest possible&nbsp;dose&nbsp;that still relieves your symptoms.<br><\/p>\n\n\n\n<p><em>Starting dose<\/em><\/p>\n\n\n\n<p>Adults, adolescents (12 years or older), and children over 6 years:<\/p>\n\n\n\n<p>The recommended starting dose is a total of&nbsp;<strong>8&nbsp;sprays<\/strong>&nbsp;(256 micrograms)&nbsp;<strong>daily<\/strong>.<br><\/p>\n\n\n\n<p>You can&nbsp;<strong>either<\/strong>&nbsp;take this medicine:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>once daily by spraying 4 times in each nostril in the morning or<\/li><li>twice daily by spraying 2 times in each nostril in the morning and 2 times in each nostril in the evening.<\/li><\/ul>\n\n\n\n<p>Children should be treated under the guidance of an adult.<br><\/p>\n\n\n\n<p>It is best if you can start taking this medicine up to 14 days before you expect your symptoms to start.&nbsp;Start taking this medicine about 2 weeks before your hay fever symptoms usually start to become a problem and stop taking this medicine when the allergy season is over.<br><\/p>\n\n\n\n<p><em>Maintenance dose<\/em><\/p>\n\n\n\n<p>It takes 7 to 14 days for the drug to work.&nbsp;If you get any effect within 14 days, consult a doctor.<br><\/p>\n\n\n\n<p>Once the effect has been achieved, the lowest possible&nbsp;dose&nbsp;should be used, which still relieves your symptoms.<\/p>\n\n\n\n<p>Using more than the recommended 8 sprays of this medicine every day does&nbsp;<b>not take<\/b> the medicine more effective.<br><\/p>\n\n\n\n<p><strong>Duration of treatment:<\/strong><\/p>\n\n\n\n<p>You must use the medicine regularly for it to work in the best way.<\/p>\n\n\n\n<p>If you do not get any immediate relief, you should continue to take the medicine regularly as it may take a few days for it to start working.<br><\/p>\n\n\n\n<p><strong>How to take the medicine<\/strong><br><\/p>\n\n\n\n<p>1. If necessary, gently cheat so that the nose is clean.<br><\/p>\n\n\n\n<p>2. Shake the bottle (Figure 1).&nbsp;Remove the protective cover.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20061216000042#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Sandoz\/Media\/Desonix\/1.jpg\" alt=\"Figure 1\"\/><\/a><\/figure>\n\n\n\n<p>Figure 1<br><\/p>\n\n\n\n<p>Hold the bottle as shown in Figure 2. Before using Desonix for the first time, you must charge the nasal applicator (ie fill it with medicine).&nbsp;Pump the nasal applicator up and down several times (5-10 times), spraying in the air until you get an even shower.&nbsp;The charging effect lasts for about 24 hours.&nbsp;If it takes longer before the next&nbsp;dose is&nbsp;taken, the nasal applicator must be charged (filled with medicine) again.&nbsp;If Desonix is \u200b\u200bused at shorter intervals, it is sufficient to spray only once in the air.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20061216000042#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Sandoz\/Media\/Desonix\/2.jpg\" alt=\"Figure 2\"\/><\/a><\/figure>\n\n\n\n<p>Figure 2<br><\/p>\n\n\n\n<p>4. Insert the tip of the nasal applicator into the nostril according to Figure 3 and spray once (or more if your doctor has prescribed it).&nbsp;Use the spray in the other nostril in the same way.&nbsp;Remember that you do not need to inhale while spraying.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20061216000042#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Sandoz\/Media\/Desonix\/3.jpg\" alt=\"Figure 3\"\/><\/a><\/figure>\n\n\n\n<p>Figure 3<br><\/p>\n\n\n\n<p>5. Wipe the tip of the nasal applicator with a clean paper towel and replace the protective cap.<br><\/p>\n\n\n\n<p>6. Store the bottle in an upright position.<br><\/p>\n\n\n\n<p><em>Cleaning your Desonix<\/em><\/p>\n\n\n\n<p>You should clean the plastic tip of the nasal applicator on Desonix regularly and always when the spray from the medicine does not come out properly.&nbsp;If this happens, first check that the nasal applicator is loaded with medication (see the previous description).&nbsp;If the nasal applicator pump still does not work after recharging it, clean the nasal applicator as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Remove the nasal applicator with a clean paper towel and rinse it in warm &#8211; not hot &#8211; water.<\/li><li>Rinse the nasal applicator thoroughly, dry it and then put it back on the top of the bottle.<\/li><li>Never attempt to clean the nasal applicator by using a needle or other pointed object.<\/li><li>After cleaning the nasal applicator, it must be recharged (filled with medicine) before it can be used.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Desonix than you should<\/h2>\n\n\n\n<p>You must take a&nbsp;dose&nbsp;as stated on the label on the package or as your doctor advised.&nbsp;Use only the amount prescribed by your doctor.&nbsp;Using too little or too much can make your symptoms worse.<\/p>\n\n\n\n<p>If you take more Desonix then you should just continue with your usual&nbsp;dose.&nbsp;It is unlikely that you will have any medical problems.<\/p>\n\n\n\n<p>But if you have taken more than 8 sprays per day for more than a month or if e.g.&nbsp;If a child has ingested the medicine by mistake, you should immediately contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Desonix<\/h2>\n\n\n\n<p>If you forget to take your medicine on time, take it as soon as possible.&nbsp;Then go back to your regular dosing schedule.&nbsp;Never take more sprays per day than according to the dosing schedule to compensate for a missed&nbsp;dose.<br><\/p>\n\n\n\n<p><strong>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>This medicine generally only treats symptoms that affect the nose (eg nasal congestion or runny nose).&nbsp;If you have previously been treated with steroid tablets or&nbsp;injections&nbsp;and your doctor has now prescribed this medicine instead, you may experience some other symptoms worsening (eg red and itchy eyes).&nbsp;If this happens, your doctor will need to treat these other symptoms differently.<\/p>\n\n\n\n<p>Side effects&nbsp;of&nbsp;nasal corticosteroids&nbsp;are&nbsp;more likely to&nbsp;occur if you have used these medicines in high&nbsp;doses&nbsp;for several months.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur during treatment with Desonix nasal spray:<br><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<p>These may occur immediately after the medicine has been used:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>occasional sneezing, dry nose, or stinging sensation in the nose<\/li><li>slightly blood-mixed mucus from the nose<\/li><li>nosebleeds (immediately after application).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swollen face, tongue and\/or throat and\/or difficulty swallowing or&nbsp;hives&nbsp;along with difficulty breathing (&nbsp;angioedema&nbsp;), in very rare cases a severe&nbsp;allergic reaction&nbsp;may&nbsp;occur: if this occurs, contact a doctor immediately<\/li><li>hives&nbsp;(itchy rash-like after burning yourself on stinging nettles)<\/li><li>rash<\/li><li>itching<\/li><li>skin irritation.<\/li><li>muscle spasm.<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anaphylactic reaction&nbsp;(severe&nbsp;allergic reaction&nbsp;)<\/li><li>osteoporosis (for long-term treatment)<\/li><li>bruises or bumps<\/li><li>increased pressure in the eyes<\/li><li>cloudy eye lens<\/li><li>dimsyn<\/li><li>areas with sores or soreness in the nose<\/li><li>perforation of the wall between the nostrils (nasal septum)<\/li><li>voice changes<\/li><li>slower growth in children and adolescents, especially after consuming high&nbsp;doses for a long time<\/li><li>Adrenal insufficiency: this can cause symptoms such as&nbsp;anorexia, abdominal pain, weight loss, nausea, headache, vomiting, decreased consciousness, low blood sugar, and seizures.&nbsp;Situations that could trigger an&nbsp;acute&nbsp;adrenal crisis are trauma,&nbsp;infection, surgery, or any form of rapid dose reduction.&nbsp;If you get these symptoms, contact your doctor immediately.<\/li><\/ul>\n\n\n\n<p>This medicine can cause&nbsp;side effects&nbsp;that affect the whole body, especially if used in high&nbsp;doses&nbsp;for a long time.&nbsp;However, these&nbsp;side effects&nbsp;are rare.<br><\/p>\n\n\n\n<p>Potassium sorbate, an ingredient in this medicine, can irritate the skin or mucous membranes, for example on the inside of the nose.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Desonix<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p>Do not freeze.<br><\/p>\n\n\n\n<p>Discard opened bottle with remaining solution after 3 months.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The&nbsp;<strong>active substance<\/strong>&nbsp;is budesonide&nbsp;<br>A&nbsp;dose of&nbsp;0.05 ml (one spray) of this nasal spray&nbsp;suspension&nbsp;contains 32 micrograms of budesonide.<\/li><li>The other ingredients are:&nbsp;<br>Dispersible&nbsp;cellulose (microcrystalline cellulose and sodium carboxymethylcellulose [89:11, w \/ w])&nbsp;<br>Polysorbate 80&nbsp;<br>Potassium sorbate E202&nbsp;<br>Glucose, anhydrous&nbsp;<br>Disodium edit&nbsp;<br>Hydrochloric acid, concentrated&nbsp;<br>Ascorbic acid&nbsp;E300&nbsp;<br>Purified water<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Desonix is \u200b\u200ba white&nbsp;homogeneous&nbsp;suspension.<br><\/p>\n\n\n\n<p>Desonix is \u200b\u200bsupplied in a brown glass bottle with a plastic spray pump and a polypropylene nasal applicator.&nbsp;Pack sizes: 1 x 120 (1 x 10 ml)&nbsp;doses&nbsp;, 3 x 120 (3 x 10 ml)&nbsp;doses&nbsp;, 10 x 120 (10 x 10 ml)&nbsp;doses&nbsp;(prescription).<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Lek Pharmaceuticals dd, Verov\u0161kova 57, 1526 Ljubljana, Slovenia<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Desonix contains budesonide, a synthetic corticosteroid. Corticosteroids are a group of drugs that work by fighting inflammation. Desonix is \u200b\u200bused for:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[4130,5756,4132,5757,5760,5759,2212,998,5758],"class_list":["post-7407","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-budesonide","tag-budesonide-nasal-spray","tag-budesonide-side-effects","tag-desonix","tag-desonix-nasal-spray","tag-desonix-side-effects","tag-medicine","tag-nasal-spray","tag-what-is-desonix"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7407"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7407\/revisions"}],"predecessor-version":[{"id":11059,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7407\/revisions\/11059"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}