adefovir dipivoxil<\/strong><\/li><\/ul>\n\n\n\n\u2192 Contact your<\/strong> doctor if you are taking any of these medicines.
<\/p>\n\n\n\nOther types of medicines:<\/strong><\/p>\n\n\n\nTalk to your doctor if you are taking:<\/p>\n\n\n\n
- antibiotics<\/strong>, used to treat bacterial infections including tuberculosis, which contain:
- rifabutin, rifampicin, and rifapentine<\/li><\/ul><\/li>
- antiviral drugs used to treat HIV :
- emtricitabine and tipranavir<\/li><\/ul><\/li>
- antiepileptics used to treat epilepsy, eg:
- carbamazepine, oxcarbazepine, phenobarbital, and phenytoin<\/li><\/ul><\/li>
- (Traditional) herbal medicines,<\/strong> used to treat mild depression and anxiety, which contain:
- St. John’s wort ( Hypericum perforatum<\/em> )<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 Tell your doctor if you are taking any of these or other medicines. <\/strong>You should not stop treatment without talking to your doctor.<\/p>\n\n\n\nPregnancy and breastfeeding<\/h2>\n\n\n\n- If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li>
- Tell your doctor immediately if you become pregnant and ask about the possible benefits or risks of your antiretroviral treatment for you and your baby.<\/li><\/ul>\n\n\n\n
If you have taken Descovy during your pregnancy, your doctor may ask you to have regular blood tests and other tests to check your baby’s development. For children whose mothers took NRTIs during pregnancy, the benefit of HIV protection outweighs the risk of side effects.
<\/p>\n\n\n\n
Do not breast-feed during treatment with Descovy. <\/strong>This is because one of the active substances in this medicine passes into breast milk. To avoid transmitting HIV to your baby through breast milk, do not breast-feed your baby.<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
Descovy can cause dizziness. Do not drive or use tools or machines if you feel dizzy while taking Descovy.<\/p>\n\n\n\n
Descovy contains excipients<\/h2>\n\n\n\n
Descovy contains sodium<\/strong><\/p>\n\n\n\nThis medicine contains less than 1 mmol (23 mg) sodium per tablet, ie it is essentially ‘sodium-free’.
<\/p>\n\n\n\n
3. How to take Descovy<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n
The recommended dose is:<\/strong>
<\/p>\n\n\n\nAdults:<\/strong> one tablet a day with or without food<\/p>\n\n\n\nAdolescents aged 12 years and older, weighing at least 35 kg:<\/strong> one tablet a day with or without food
<\/p>\n\n\n\nYou must not chew, crush or split the tablet.
<\/p>\n\n\n\n
Always take the dose prescribed<\/strong> by your <\/strong>doctor<\/strong> to ensure that the medicine is effective and to reduce the risk of developing resistance to treatment. Do not change the dose unless your doctor tells you to.
<\/p>\n\n\n\nIf you are on dialysis<\/strong>, you should take your daily dose of Descovy after dialysis has been completed.<\/p>\n\n\n\nIf you take more Descovy than you should<\/h2>\n\n\n\n
If you take more than the prescribed dose of Descovy you may be at greater risk of side effect s of this medicine (see section 4, Possible side effects s<\/em> ).
<\/p>\n\n\n\nContact your doctor or nearest emergency department immediately for advice. Save the jar so you can show what you have taken.<\/p>\n\n\n\n
If you forget to take Descovy<\/h2>\n\n\n\n
You mustn’t miss a dose of Descovy.<\/p>\n\n\n\n
If you miss a dose:<\/p>\n\n\n\n
- If you notice it within 18 hours<\/strong> after the time you usually take Descovy, you must take the tablet as soon as possible. Then take the next dose as usual.<\/li>
- If you notice it 18 hours or more<\/strong> after the time you usually take Descovy, do not take the missed dose. Wait and take the next dose at its regular time.<\/li><\/ul>\n\n\n\n
If you vomit within less than 1 hour after a dose of Descovy,<\/strong> take a new tablet.<\/p>\n\n\n\nDo not stop taking Descovy<\/h2>\n\n\n\n
Do not stop taking Descovy without talking to your doctor. <\/strong>If you stop taking Descovy, it can seriously affect how well a future treatment works. If for any reason you stop taking Descovy, talk to your doctor before taking Descovy tablets again.
<\/p>\n\n\n\nWhen you start to run out of Descovy<\/strong>, get more from your<\/strong> doctor or pharmacist. This is very important because the amount of virus can start to increase even if you only stop taking the medicine for a short time. The disease can then become more difficult to treat.
<\/p>\n\n\n\nIf you have both HIV – infection and hepatitis B,<\/strong> it is very important not to stop Descovy treatment without first talking to your doctor. You may need to submit blood samples for several months after stopping treatment. In some patients with advanced liver disease or cirrhosis, hepatitis A may worsen if treatment is stopped, which can be life-threatening.
<\/p>\n\n\n\n\u2192 Tell your doctor immediately<\/strong> about any new and unexpected symptoms that occur after stopping treatment, especially symptoms that you usually associate with your hepatitis B infection.
<\/p>\n\n\n\nIf you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
Possible serious side effects: Contact a doctor immediately<\/strong><\/p>\n\n\n\n- Signs of inflammation or infection<\/strong>. In some patients with advanced HIV – infection ( AIDS ) who have a history of opportunistic infection, you ( infection s that occurs in people with a weakened immune system), signs and symptoms of inflammation from previous infections you behave shortly after antiretroviral treatment has begun. It is believed that these symptoms are because the body’s immune system has been strengthened so that the body can fight infections that may have been present without giving any clear symptoms.<\/li>
- Autoimmune disease (the immune system attacks healthy body tissue) may also occur after you start taking medicines for HIV – infection. Autoimmune diseases can occur many months after starting treatment. Be observant of symptoms of infection or other symptoms such as:
- muscle weakness<\/li>
- weakness that begins in the hands and feet and moves towards the torso<\/li>
- palpitations, tremors, or hyperactivity.<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 If you notice the side effects described above, tell your doctor immediately.<\/strong>
<\/p>\n\n\n\nVery common side effects are<\/strong><\/p>\n\n\n\n( may occur in more than 1 in 10 people<\/em> )<\/p>\n\n\n\n- nausea<\/li><\/ul>\n\n\n\n
Common side effects are<\/strong><\/p>\n\n\n\n( may occur in up to 1 in 10 people<\/em> )<\/p>\n\n\n\n- abnormal dreams<\/li>
- headache<\/li>
- dizziness<\/li>
- diarrhea<\/li>
- vomiting<\/li>
- abdominal pain<\/li>
- gas production ( flatulence )<\/em><\/li>
- rash<\/li>
- fatigue<\/li><\/ul>\n\n\n\n
Uncommon side effects are<\/strong><\/p>\n\n\n\n( may occur in up to 1 in 100 people<\/em> )<\/p>\n\n\n\n- low red blood cell count ( anemia<\/em> )<\/li>
- indigestion which results in discomfort after meals ( dyspepsia )<\/em><\/li>
- swelling of the face, lips, tongue, or throat ( angioedema<\/em> )<\/li>
- itching ( pruritus<\/em> )<\/li>
- hives ( urticaria<\/em> )<\/li>
- joint pain ( arthralgia<\/em> )<\/li><\/ul>\n\n\n\n
\u2192 <\/strong> If any side effects get worse, talk to your doctor.<\/strong>
<\/p>\n\n\n\nOther effects that can be seen with HIV treatment<\/strong>
<\/p>\n\n\n\nThe frequency of the following side effects is unknown (frequency cannot be calculated from the available data).<\/p>\n\n\n\n
- Skeletal problem. <\/strong>Some patients taking combination antiretroviral medicines like Descovy may develop a skeletal disease called osteonecrosis<\/em> (bone tissue dies due to lost blood supply to the skeleton). Some of the many risk factors for developing this disease are long-term use of this type of drug, treatment with corticosteroids, alcohol consumption, a very weak immune system, and obesity. Signs of osteonecrosis are:
- joint stiffness<\/li>
- joint pain and pain (especially in hips, knees, and shoulders)<\/li>
- mobility difficulties<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 <\/strong> Tell your doctor if you notice any of these symptoms.<\/strong>
<\/p>\n\n\n\nDuring HIV treatment, weight gain and increased levels of lipids and glucose in the blood may occur. This is partly related to restored health and lifestyle, but when it comes to blood lipids, there can sometimes be a connection with HIV drugs. The doctor will perform tests to find such changes.
<\/p>\n\n\n\n
5. How to store Descovy<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton and jar after \u201cEXP\u201d. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Store in the original package. Moisture sensitive. Close the jar tightly.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances<\/strong> are emtricitabine and tenofoviralafenamide. One Descovy film-coated tablet contains 200 mg emtricitabine and tenofoviralafenamide fumarate equivalent to 10 mg tenofoviralafenamide.<\/p>\n\n\n\nOther ingredients are<\/strong><\/p>\n\n\n\nTablet core:<\/em><\/p>\n\n\n\nMicrocrystalline cellulose, croscarmellose sodium, magnesium stearate.<\/p>\n\n\n\n
Film coating:<\/em><\/p>\n\n\n\nPolyvinyl alcohol, titanium dioxide, macrogol 3350, talc, black iron oxide (E172).<\/p>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Descovy film-coated tablets are gray, rectangular tablets. Embossed on one side with “GSI” and on the other side with the number “210”.
<\/p>\n\n\n\n
Descovy is supplied in jars containing 30 tablets (with desiccant in the form of silica gel which must be stored in the jar to protect the tablets from moisture). The desiccant (silica gel) is in a separate sachet or container and should not be swallowed.
<\/p>\n\n\n\n
The following pack sizes are available: Outer cartons containing 1 can of 30 film-coated tablets and outer cartons containing 60 (2 cans of 30) and 90 (3 cans of 30) film-coated tablets. Not all pack sizes may be marketed.
<\/p>\n\n\n\n
Marketing Authorisation Holder:<\/h2>\n\n\n\n
Gilead Sciences Ireland UC<\/p>\n\n\n\n
Carrigtohill<\/p>\n\n\n\n
County Cork, T45 DP77<\/p>\n\n\n\n
Ireland
<\/p>\n\n\n\n
Manufacturer:<\/strong><\/p>\n\n\n\nGilead Sciences Ireland UC<\/p>\n\n\n\n
IDA Business & Technology Park<\/p>\n\n\n\n
Carrigtohill<\/p>\n\n\n\n
County Cork<\/p>\n\n\n\n
Ireland
<\/p>\n\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Descovy contains two active substances:. Descovy blocks the activity of reverse transcriptase, an enzyme necessary for the virus to multiply. Therefore, Descovy reduces the amount of HIV in the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5866,5871,5868,5869,5870,3398,3400,3401,4328,3399,5872,5876,5874,5877,5875,5867,4318,5873],"class_list":["post-7339","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-descovy","tag-descovy-dose","tag-descovy-side-effects","tag-descovy-tablet","tag-descovy-uses","tag-emtricitabine","tag-emtricitabine-dose","tag-emtricitabine-side-effects","tag-emtricitabine-tablet","tag-emtricitabine-uses","tag-tenofoviralafenamide","tag-tenofoviralafenamide-dose","tag-tenofoviralafenamide-side-effects","tag-tenofoviralafenamide-tablet","tag-tenofoviralafenamide-uses","tag-what-is-descovy","tag-what-is-emtricitabine","tag-what-is-tenofoviralafenamide"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7339","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7339"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7339\/revisions"}],"predecessor-version":[{"id":11093,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7339\/revisions\/11093"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7339"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7339"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7339"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}