{"id":7337,"date":"2021-02-21T08:40:40","date_gmt":"2021-02-21T08:40:40","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7337"},"modified":"2021-05-26T10:01:10","modified_gmt":"2021-05-26T10:01:10","slug":"dermovat","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/dermovat\/","title":{"rendered":"Dermovat &#8211; Clobetasol Propionate uses, dose and side effects"},"content":{"rendered":"\n<p>Dermovat cream 0.05%, Dermovat ointment 0.05%, Dermovat cutaneous solution 0.5 mg \/ ml<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Dermovat is and what it is used for<\/h2>\n\n\n\n<p>Dermovat is used in the treatment of severe cases of&nbsp;psoriasis&nbsp;(uncommon plaque psoriasis) and&nbsp;eczema.<\/p>\n\n\n\n<p>The ointment is suitable for dry and scaly skin changes, while the&nbsp;cream&nbsp;is better suited for exfoliating skin changes.&nbsp;The solution is intended for the treatment of the scalp but can also be used on other parts of the body.<\/p>\n\n\n\n<p>Dermovat is an extra strong-acting cortisone preparation (group IV) that counteracts&nbsp;inflammation&nbsp;and has an antipruritic effect.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Dermovat<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Dermovat<\/h2>\n\n\n\n<p>If you are allergic to clobetasol or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>in infected skin (unless&nbsp;the infection is&nbsp;co-treated with&nbsp;an antimicrobial&nbsp;therapy)<\/li><li>in&nbsp;acne<\/li><li>in&nbsp;rosacea&nbsp;(skin problems where the nose, cheeks, chin, forehead, or whole face are unusually red, with or without visible blood vessels)<\/li><li>in case of rash around the mouth (perioral&nbsp;dermatitis&nbsp;)<\/li><li>in case of&nbsp;itching&nbsp;of the skin without&nbsp;inflammation<\/li><li>around the anus or genitals (penis and&nbsp;vagina&nbsp;)<\/li><li>in the treatment of children under 1 year.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Local&nbsp;hypersensitivity reactions&nbsp;such as redness of the skin, rash,&nbsp;itching,&nbsp;hives, burning sensation, and contact dermatitis may occur.&nbsp;Should any skin reaction occur, treatment must be stopped immediately?<\/li><li>Talk to your doctor if you have previously had a&nbsp;hypersensitivity reaction&nbsp;to any cortisone preparation.<\/li><li>Only use Dermovat for as long as your doctor recommends it.&nbsp;If no improvement occurs within 2-4 weeks of treatment, talk to your doctor.<\/li><li>Be careful when applying Dermovat to the eyelids.&nbsp;Avoid getting Dermovat in your eyes.<\/li><li>Be careful when applying Dermovat to the face for a long time as it can lead to skin thinning.<\/li><li>If you have&nbsp;dermatitis&nbsp;(&nbsp;inflammation&nbsp;of the skin) around a leg ulcer,&nbsp;your&nbsp;corticosteroid&nbsp;may&nbsp;increase the risk of an&nbsp;allergic reaction&nbsp;or&nbsp;infection&nbsp;around the leg ulcer.<\/li><li>If you have&nbsp;psoriasis, your doctor will want to see you more often as there is a risk of&nbsp;tolerance development&nbsp;and relapse.<\/li><li>Bandages should be avoided in infected&nbsp;eczema.&nbsp;Only use a dressing if your doctor has recommended it.&nbsp;If Dermovat is applied under a dressing, clean the skin before applying a new dressing to prevent&nbsp;infection.<\/li><li>Dermovat is not normally suitable for the treatment of children.&nbsp;Do not use it in children without a doctor&#8217;s&nbsp;prescription.<\/li><li>Sensitive skin areas e.g.&nbsp;The face, armpits, groin, and eye region should only be treated briefly.<\/li><li>Cortisone preparations can mask, activate or aggravate a skin infection.<\/li><li>Using a high&nbsp;dose of&nbsp;Dermovat for a long time can cause&nbsp;cortisone to&nbsp;affect the whole body.&nbsp;Symptoms such as weight gain with altered fat distribution (abdomen, neck, face), thin and brittle skin, increased body hair, decreased bone density, high&nbsp;blood pressure&nbsp;can then occur (Cushing&#8217;s syndrome).&nbsp;In children and young people, growth retardation can be seen.&nbsp;If any of these are observed, contact your treating physician for gradual discontinuation of treatment by reducing the frequency of application or by switching to a less&nbsp;potent corticosteroid.&nbsp;Abrupt discontinuation of treatment may result in glucocorticoid deficiency (see&nbsp;side effects&nbsp;).<\/li><li>Contact a doctor if you experience blurred vision or other visual disturbances.<\/li><\/ul>\n\n\n\n<p>After applying Dermovat, hands should be washed thoroughly, unless hands are to be treated.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Dermovat<\/h2>\n\n\n\n<p>Some medicines may affect the way Dermovat works or increase the risk of&nbsp;side effects.&nbsp;Examples of<\/p>\n\n\n\n<p>these drugs are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ritonavir (drug against&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;s).<\/li><li>Itraconazole (a medicine used to treat fungal infections).<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>There is a risk that the fetus is affected.&nbsp;Therefore, always consult a doctor before using Dermovat during pregnancy.<br><\/p>\n\n\n\n<p>Talk to your doctor&nbsp;<em>before<\/em>&nbsp;using Dermovat during breast-feeding.&nbsp;Never apply Dermovat to your breasts while breast-feeding to avoid accidentally getting Dermovat in your mouth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No known effect on the ability to drive or perform precision work with concomitant use of Dermovat.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Excipients<\/h2>\n\n\n\n<p>Dermovat&nbsp;<strong>cream<\/strong>&nbsp;contains&nbsp;<strong>chlorocresol<\/strong>&nbsp;which may cause allergic reactions and&nbsp;<strong>cetostearyl alcohol<\/strong>&nbsp;which may cause local skin reactions (eg contact dermatitis).<br><\/p>\n\n\n\n<p>Dermovat&nbsp;<strong>cream&nbsp;and ointment<\/strong>&nbsp;contain&nbsp;<strong>propylene glycol.<\/strong><\/p>\n\n\n\n<p>Dermovat&nbsp;cream&nbsp;contains 475 mg of propylene glycol per gram.<\/p>\n\n\n\n<p>Dermovat ointment contains 50 mg of propylene glycol per gram.<\/p>\n\n\n\n<p>Propylene glycol may cause skin irritation.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Dermovat<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><em>Recommended dosage:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Use Dermovat once or twice daily for a maximum of four weeks.&nbsp;How often your iron can be reduced as your skin improves or your doctor will prescribe a weaker&nbsp;steroid&nbsp;for you to use instead.<br><\/li><\/ul>\n\n\n\n<p>How to use Dermovat:<\/p>\n\n\n\n<p><em>Cream&nbsp;and ointment<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Apply thinly and lubricate carefully according to the doctor&#8217;s prescription.&nbsp;Use only so much that it just covers the area to be treated.<\/li><li>After applying Dermovat, hands should be washed thoroughly, unless hands are to be treated.<\/li><li>This medicine should not be used every day for more than four weeks at a time.<\/li><\/ul>\n\n\n\n<p>If your&nbsp;eczema&nbsp;flares up frequently, your doctor may suggest using a less frequent&nbsp;dose&nbsp;of Dermovat when your&nbsp;eczema&nbsp;is under control, to prevent your&nbsp;eczema&nbsp;from returning.<br><\/p>\n\n\n\n<p><em>Cutaneous&nbsp;solution<\/em><\/p>\n\n\n\n<p>If you wash or shampoo your hair, it should be dry before applying the cutaneous solution.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Unscrew the cap and place the nozzle on the scalp to be treated.&nbsp;Gently press on the bottle to cover with a thin and even layer of solution.&nbsp;You can massage in the solution, but you do not have to.&nbsp;Your scalp may feel cold until the solution has dried.<\/li><li>In case of very strong scaling on the scalp, the scalp should first be cleaned with salicylic acid-containing preparations and\/or shampooing before the solution is dripped on and massaged into the changed skin area.<\/li><\/ul>\n\n\n\n<p>Children, the elderly, and patients with hepatic or renal impairment should be treated with the least possible amount for the shortest possible time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Dermovat then you should<\/h2>\n\n\n\n<p>Acute&nbsp;overdose is unlikely, but in case of prolonged overdose or misuse, always contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>When treating large areas for a long time or when treating with dressings, the risk of&nbsp;side effects&nbsp;increases.<br><\/p>\n\n\n\n<p>If a skin reaction occurs, your skin problem gets worse or if your skin becomes swollen during treatment, you may be allergic to the medicine, have an&nbsp;infection,&nbsp;or need another treatment.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Discontinue Dermovat immediately, contact your doctor as soon as possible.<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin itching<\/li><li>local burning sensation or pain in the skin.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>thinning skin that can cause stretch marks<\/li><li>rash on the face (&nbsp;rosacea&nbsp;)<\/li><li>stretch marks in superficial blood vessels<\/li><li>hypersensitivity to the preservative chlorocresol in&nbsp;cream&nbsp;one.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hypersensitivity to the active substance clobetasol in&nbsp;cream, ointment, and cutaneous solution.<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inhibition of adrenal cortex function<\/li><li>pigment changes<\/li><li>increased hair<\/li><li>worsening of the skin disease<\/li><li>Local&nbsp;hypersensitivity&nbsp;s<\/li><li>reddening of the skin<\/li><li>rash<\/li><li>urticaria&nbsp;(&nbsp;hives&nbsp;)<\/li><li>itching<\/li><li>irritation\/pain at the application site<\/li><li>contact dermatitis\/skin infection at the application site<\/li><li>visible blood vessels under the skin<\/li><li>skin thinning<\/li><li>wrinkles on the skin<\/li><li>dry skin<\/li><li>If you have&nbsp;psoriasis, lumps may appear under the skin.&nbsp;This is uncommon and can occur during or after treatment and is known as pustular&nbsp;psoriasis<\/li><li>cushingoid features (moon face, central obesity)<\/li><li>weight gain\/obesity<\/li><li>delayed weight gain\/growth retardation in children<\/li><li>the weakening of the skeleton (&nbsp;osteoporosis&nbsp;)<\/li><li>increased pressure in the eye (&nbsp;glaucoma&nbsp;)<\/li><li>cataract (&nbsp;cataract&nbsp;)<\/li><li>vision problems caused by detachment of the retina of the eye (central serous chorioretinopathy)<\/li><li>increased blood sugar and urine levels<\/li><li>high&nbsp;blood pressure<\/li><li>hair loss, lack of hair growth, damaged hair<\/li><li>decreased levels of&nbsp;cortisol&nbsp;in the blood<\/li><li>infection&nbsp;that occurs due to a weakened immune system (&nbsp;opportunistic infection&nbsp;)<\/li><li>acne.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tamsyn.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Dermovat<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store cream&nbsp;and ointment at a maximum of 30 \u00b0 C.<\/li><li>The cutaneous&nbsp;solution is stored at a maximum of 25\u00baC.&nbsp;Keep the container tightly closed when not in use.&nbsp;Do not store Dermovat&nbsp;cutaneous&nbsp;solution in direct sunlight.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is clobetasol.<br><\/p>\n\n\n\n<p>1 g of&nbsp;cream&nbsp;contains 0.5 mg of clobetasol (as clobetasol propionate).&nbsp;The other ingredients are glycerol monostearate, cetostearyl alcohol, stearoyl macrogol glycerides, white wax, sodium citrate, citric acid monohydrate, propylene glycol, purified water, chlorocresol (&nbsp;preservative&nbsp;).<br><\/p>\n\n\n\n<p>1 g ointment contains 0.5 mg clobetasol (as clobetasol propionate).&nbsp;The other ingredients are propylene glycol, sorbitan sesquiplane, white petrolatum.<br><\/p>\n\n\n\n<p>1 ml of&nbsp;cutaneous&nbsp;solution contains 0.5 mg clobetasol (as clobetasol propionate).&nbsp;The other ingredients are carbomer, isopropyl alcohol, sodium hydroxide, purified water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Dermovat&nbsp;cream&nbsp;is white and is supplied in aluminum tubes containing 25 g, 30 g, or 100 g.<br><\/p>\n\n\n\n<p>Dermovat ointment is white to translucent and is supplied in aluminum tubes containing 25 g, 30 g, or 100 g.<br><\/p>\n\n\n\n<p>Demovat&nbsp;cutaneous&nbsp;solution is a clear, clear solution and is supplied in a plastic bottle containing 100 ml.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>GlaxoSmithKline AB, Box 516, 169 29 Solna<\/p>\n\n\n\n<p>Tel: 08-638 93 00<\/p>\n\n\n\n<p>Email: info.produkt@gsk.com<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dermovat is used in the treatment of severe cases of psoriasis (uncommon plaque psoriasis) and eczema.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5878,5881,5882,5880,5883,5886,5887,5885,5879,5884],"class_list":["post-7337","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-clobetasol-propionate","tag-clobetasol-propionate-cream","tag-clobetasol-propionate-ointment","tag-clobetasol-propionate-side-effects","tag-dermovat","tag-dermovat-cream","tag-dermovat-ointment","tag-dermovat-side-effects","tag-what-is-clobetasol-propionate","tag-what-is-dermovat"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7337"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7337\/revisions"}],"predecessor-version":[{"id":11095,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7337\/revisions\/11095"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}