\n\n25 mg or 100 mg film-coated tablets
glass dough<\/p>\n\n\n\n
Daurismo is a cancer drug that contains the active substance glasdegib.
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Daurismo is used in combination with another cancer drug, cytarabine, to treat adults who have recently been diagnosed with a type of blood cancer called acute myeloid leukemia (AML).
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This is how Daurismo works<\/strong><\/p>\n\n\n\n In AML, there are cancer cells called stem cells, which constantly create new leukemic cancer cells. Daurismo works by blocking a key process, called the Hedgehog (Hh) signaling pathway, in these stem cells. In this way, their ability to create new cancer cells is weakened. By blocking the Hh signaling pathway, Daurismo can also make cancer cells more sensitive to a cancer drug, cytarabine, which is used to treat AML. When you combine Daurismo with the drug cytarabine, you can increase the patient’s life expectancy, as it reduces the growth of cancer and possibly kills more cancer cells. Contact your doctor if you have any questions about how Daurismo works or why you have been given this medicine.<\/p>\n\n\n\n <\/p>\n\n\n\n – if you are allergic to glass dough or any of the other ingredients of this medicine (listed in section 6). Talk to your doctor, pharmacist, or nurse before taking Daurismo<\/p>\n\n\n\n Tell your doctor immediately when you take this medicine<\/p>\n\n\n\n Daurismo should not be used in patients under 18 years of age. Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines. This includes over-the-counter medicines and herbal medicines. This is because Daurismo may affect the way other medicines work. Some other medicines may affect the way Daurismo works. In particular, the following medicines may increase the risk of side effects with Daurismo:<\/p>\n\n\n\n The following medicines may reduce the effect of Daurismo:<\/p>\n\n\n\n Do not drink grapefruit juice or eat grapefruit during treatment with Daurismo, as this may affect the amount of Daurismo in your body. Pregnancy<\/p>\n\n\n\n You must not become pregnant while taking Daurismo and you must not take the medicine if you are pregnant. Daurismo can cause serious congenital malformations in infants or lead to fetal death. Your doctor will give you more information about the effects of Daurismo on the fetus. You will also have to do a pregnancy test before you start taking the medicine. You must tell your doctor immediately if you or your partner become pregnant or are thought to be pregnant during your treatment and for 30 days after your last dose of Turismo. If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Contraceptives in women and men<\/p>\n\n\n\n Women<\/em><\/p>\n\n\n\n You should always use effective contraception while you are taking Daurismo and for at least 30 days after your last dose of Daurismo. Talk to your doctor about which contraceptive methods are right for you and your partner. Men<\/em><\/p>\n\n\n\n You should always use effective contraception, including condoms (with spermicides, if available), even if you have undergone a vasectomy, while you are taking Daurismo and for at least 30 days after your last dose of Daurismo. You should not donate semen while taking Daurismo and at least 30 days after your last dose. Breast-feeding<\/p>\n\n\n\n Do not breast-feed while you are taking Daurismo or for a week after your last dose of Daurismo. It is not known if Daurismo passes into breast milk and harms your baby. Fertility<\/p>\n\n\n\n Daurismo can affect the fertility of both men and women. Talk to your doctor about fertility preservation measures before taking Daurismo. If you feel tired or experience muscle cramps, pain, or nausea during your treatment with Daurismo, you should be especially careful when driving or using machines. This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie it is essentially ‘sodium-free’. Daurismo contains lactose<\/strong><\/p>\n\n\n\n This medicine contains lactose (found in milk and dairy products).<\/p>\n\n\n\n <\/p>\n\n\n\n Take Daurismo once a day at about the same time each day. Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure. The recommended dose is a 100 mg tablet taken orally once a day, with or without food. If you get some side effects is when you take Daurismo (see section 4, “Possible side effects”) may be the doctor will lower your dose or stop treatment, either temporarily or permanently. If you vomit after taking Daurismo<\/strong><\/p>\n\n\n\n If you vomit after taking a dose of Daurismo, do not take an extra dose, just take the next dose at the usual time. If you happen to take too many tablets, tell your doctor, pharmacist, or nurse immediately. You may need to seek emergency medical attention. If you forget to take a tablet, take it as soon as you remember unless more than 10 hours have passed since the scheduled dosing time. In such cases, skip dose one. Do not take a double dose to make up for a forgotten dose. Do not stop taking Daurismo unless your doctor tells you to. You must take Daurismo every day, as long as your doctor prescribes it for you. If you are unable to take the medicine as prescribed by your doctor or if you feel you no longer need it, talk to your doctor straight away. If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse. Like all medicines, this medicine can cause side effects, although not everybody gets them. Daurismo can cause serious congenital malformations. It can also lead to the death of the fetus or the death of the baby shortly after birth. You should not become pregnant while taking this medicine (see section 2, \u201cWhat you need to know before taking Daurismo\u201d). Other side effects of Daurismo, in combination with cytarabine, include: Very common: may affect more than 1 user in 10<\/p>\n\n\n\n Common: may affect up to 1 in 10 users<\/p>\n\n\n\n <\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and blister or can after EXP. The expiration date is the last day of the specified month. No special storage instructions. Do not use this medicine if the package is damaged or appears to have been tampered with. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. Daurismo 25 mg film-coated tablets Daurismo 100 mg film-coated tablets <\/p>\n\n\n\n Not all pack sizes may be marketed. Pfizer Europe MA EEIG<\/p>\n\n\n\n Boulevard de la Plaine 17<\/p>\n\n\n\n 1050 Brussels<\/p>\n\n\n\n Belgium Manufacturer<\/strong><\/p>\n\n\n\n Pfizer Manufacturing Deutschland GmbH<\/p>\n\n\n\n Company Freiburg<\/p>\n\n\n\n Mooswaldallee 1<\/p>\n\n\n\n 79090 Freiburg<\/p>\n\n\n\n Germany Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n Daurismo is used in combination with another cancer drug, cytarabine, to treat adults who have recently been diagnosed with a type of blood cancer called acute myeloid leukemia (AML).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[6056,6058,6051,6053,6055,2212,6059,6054,2211,6057,6052],"class_list":["post-7301","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-daurismo","tag-daurismo-side-effects","tag-glasdegib","tag-glasdegib-side-effects","tag-glasdegib-tablet","tag-medicine","tag-side-effects-of-daurismo","tag-side-effects-of-glasdegib","tag-tablets","tag-what-is-daurismo","tag-what-is-glasdegib"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7301"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7301\/revisions"}],"predecessor-version":[{"id":11133,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7301\/revisions\/11133"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/p>\n\n\n\n2. What you need to know before using Daurismo<\/h2>\n\n\n\n
Do not use Daurismo<\/h2>\n\n\n\n
<\/p>\n\n\n\nWarnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
<\/p>\n\n\n\nOther medicines and Daurismo<\/h2>\n\n\n\n
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<\/li><\/ul>\n\n\n\nDaurismo with food, drink, and alcohol<\/h2>\n\n\n\n
<\/p>\n\n\n\nPregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
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<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
<\/p>\n\n\n\nDaurismo contains sodium<\/h2>\n\n\n\n
<\/p>\n\n\n\n3. How to use Daurismo<\/h2>\n\n\n\n
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<\/p>\n\n\n\nIf you use more Daurismo than you should <\/h2>\n\n\n\n
<\/p>\n\n\n\nIf you forget to use Daurismo<\/h2>\n\n\n\n
<\/p>\n\n\n\nIf you stop using Daurismo<\/h2>\n\n\n\n
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<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/p>\n\n\n\n5. How to store Daurismo<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
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<\/li><\/ul>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
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<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
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<\/p>\n\n\n\nBelgique \/ Belgi\u00eb \/ Belgien<\/strong>Pfizer SA \/ NVTel: +32 (0) 2 554 62 11<\/td> Lithuania<\/strong>Pfizer Luxembourg SARL branches in LithuaniaTel. + 370 52 51 4000<\/td><\/tr> Bulgaria<\/strong>Pfizer Luxembourg SAAR\u041b, Clone of BulgariaTel: +359 2 970 4333<\/td> Luxembourg \/ Luxemburg<\/strong>Pfizer SATel: +32 (0) 2 554 62 11<\/td><\/tr> Czech Republic<\/strong>Pfizer, spol. s roTel .: +420 283 004 111<\/td> Hungary<\/strong>Pfizer Kft.Tel .: + 36-1-488-37-00<\/td><\/tr> Denmark<\/strong>Pfizer ApSTel: +45 44 20 11 00<\/td> Malta<\/strong>Vivian Corporation Ltd.Tel. +356 21344610<\/td><\/tr> Germany<\/strong>Pfizer Pharma GmbHTel: +49 (0) 30 550055 51000<\/td> The Netherlands<\/strong>Pfizer bvTel: +31 (0) 10 406 43 01<\/td><\/tr> Eesti<\/strong>Pfizer Luxembourg SARL Eesti subsidiaryTel .: +372 666 7500<\/td> Norway<\/strong>Pfizer ASTel: +47 67 52 61 00<\/td><\/tr> Greece<\/strong>Pfizer A\u03bb\u03bb\u03ac\u03c2 AE.:\u0397\u03bb .: +30 210 6785 800<\/td> Austria<\/strong>Pfizer Corporation Austria Ges.mbHTel: +43 (0) 1 521 15-0<\/td><\/tr> Spain<\/strong>Pfizer, SLTel: +34 91 490 99 00<\/td> Poland<\/strong>Pfizer Polska Sp.zooTel .: +48 22 335 61 00<\/td><\/tr> France<\/strong>PfizerTel: +33 (0) 1 58 07 34 40<\/td> Portugal<\/strong>Pfizer Laboratories, Lda.Tel: +351 21 423 5500<\/td><\/tr> Croatia<\/strong>Pfizer Croatia dooTel: +385 1 3908 777<\/td> Romania<\/strong>Pfizer Romania SRLTel: +40 (0) 21 207 28 00<\/td><\/tr> Ireland<\/strong>Pfizer Healthcare IrelandTel: 1800 633 363 (toll free)+44 (0) 1304 616161<\/td> Slovenia<\/strong>Pfizer Luxembourg SARLPfizer, a company in the field of pharmaceuticals, LjubljanaTel .: + 386 (0) 1 52 11 400<\/td><\/tr> Iceland<\/strong>Icepharma hf.Phone: +354 540 8000<\/td> Slovak Republic<\/strong>Pfizer Luxembourg SARL, organizerTel .: + 421 2 3355 5500<\/td><\/tr> Italy<\/strong>Pfizer SrlTel: +39 06 33 18 21<\/td> Finland \/ Finland<\/strong>Pfizer OyPuh.\/Tel: +358 (0) 9 43 00 40<\/td><\/tr> Latvia<\/strong>Pfizer Luxembourg SARL subsidiary Latvij\u0101Tel .: + 371 670 35 775<\/td> United Kingdom<\/strong>Pfizer LimitedTel: +44 (0) 1304 616161<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"