{"id":7259,"date":"2021-02-20T06:23:53","date_gmt":"2021-02-20T06:23:53","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7259"},"modified":"2021-05-28T09:17:54","modified_gmt":"2021-05-28T09:17:54","slug":"dasatinib-krka","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/dasatinib-krka\/","title":{"rendered":"Dasatinib Krka &#8211; Dasatinib uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n20 mg, 50 mg, 70 mg, 80 mg, 100 mg and 140 mg&nbsp;film-coated tablets&nbsp;<br>dasatinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Dasatinib Krka is and what it is used for<\/h2>\n\n\n\n<p>Dasatinib Krka contains the active substance dasatinib.<br><\/p>\n\n\n\n<p>This medicine is used to treat Philadelphia chromosome-positive (Ph +)&nbsp;acute lymphocytic&nbsp;leukemia&nbsp;(ALL) in adults who have not responded to previous treatment, as well as in adolescents and children at least 1 year old.&nbsp;Leukemia&nbsp;is a cancer of white&nbsp;blood cells.&nbsp;The white&nbsp;blood cells&nbsp;usually help the body fight&nbsp;infection.&nbsp;ALL is a form of&nbsp;leukemia in&nbsp;which the&nbsp;white blood cells&nbsp;called&nbsp;lymphocytes&nbsp;are formed too fast and live too long.&nbsp;Dasatinib Krka inhibits the growth of these leukemic cells.&nbsp;Ask your doctor if you are wondering how Dasatinib Krka works or why this medicine has been prescribed for you.<br><\/p>\n\n\n\n<p>Dasatinib contained in Dasatinib Krka may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Dasatinib Krka<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Dasatinib Krka<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to dasatinib or any of the other ingredients of this medicine (listed in section 6).&nbsp;<strong>If you think you may be allergic, ask your doctor for advice.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Dasatinib Krka.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are being treated with medicines that are blood thinners or prevent blood clots (see \u201cOther medicines and Dasatinib Krka\u201d)<\/li><li>if you have a liver or heart disease, or if you have had one<\/li><li>if you have difficulty breathing, chest pain, or cough while taking Dasatinib Krka.&nbsp;It may be a sign of fluid accumulation in the lungs or chest (which may occur more often in patients 65 years of age or older) or may be due to changes in the blood vessels that supply the lungs<\/li><li>if you have ever had or may have a&nbsp;hepatitis&nbsp;B&nbsp;infection.&nbsp;The reason for this is that Dasatinib Krka can cause your&nbsp;hepatitis&nbsp;B to become active again, which in some cases can be fatal.&nbsp;Patients will be closely monitored by their doctor for signs of this&nbsp;infection&nbsp;before starting treatment.<\/li><li>Contact your doctor if you experience bruising, bleeding, fever, tiredness, and confusion while taking Dasatinib Krka.&nbsp;This can be a sign of damage to blood vessels, so-called thrombotic microangiopathy (TMA).<\/li><\/ul>\n\n\n\n<p>You will be checked regularly by your doctor to determine if Dasatinib Krka has the desired effect.&nbsp;You will also have regular blood tests when taking Dasatinib Krka.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children under 1 year of age.&nbsp;Experience with Dasatinib Krka in this age group is limited.&nbsp;Skeletal bone growth and development will be monitored in children treated with Dasatinib Krka.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Dasatinib Krka<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Dasatinib Krka is mainly processed in the liver.&nbsp;Some medicines may affect the effect of Dasatinib Krka when used at the same time.<br><\/p>\n\n\n\n<p><strong>The following medicines should not be used at the same time as Dasatinib Krka:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ketoconazole, itraconazole &#8211; these are medicines for fungal diseases<\/li><li>erythromycin, clarithromycin, telithromycin &#8211; these are&nbsp;antibiotics<\/li><li>ritonavir &#8211; this is a medicine for viral diseases<\/li><li>phenytoin, carbamazepine, phenobarbital &#8211; these are for the treatment of&nbsp;epilepsy<\/li><li>rifampicin &#8211; this is for the treatment of&nbsp;tuberculosis<\/li><li>famotidine, omeprazole &#8211; these are drugs that inhibit gastric acid production<\/li><li>St. John&#8217;s wort&nbsp;&#8211; (traditional) herbal medicine used to treat mild depression and mild anxiety (also known as&nbsp;<em>Hypericum perforatum<\/em>&nbsp;)<\/li><\/ul>\n\n\n\n<p>Do not use medicines that neutralize stomach acid (antacids such as aluminum hydroxide or&nbsp;magnesium hydroxide&nbsp;) from 2 hours before to 2 hours after taking Dasatinib Krka.<br><\/p>\n\n\n\n<p>Tell your doctor if you are taking medicines that are blood thinners or prevent blood clots.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dasatinib Krka with food, drink, and alcohol<\/h2>\n\n\n\n<p>Do not take Dasatinib Krka with grapefruit or grapefruit juice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or think you may be pregnant, tell your doctor immediately.&nbsp;Dasatinib Krka should not be used during pregnancy unless clearly necessary.&nbsp;Your doctor will discuss the possible risks of taking Dasatinib Krka during pregnancy.<br><\/p>\n\n\n\n<p>Both women and men will be advised to use effective contraception during treatment with Dasatinib Krka.<br><\/p>\n\n\n\n<p>Tell your doctor if you are breast-feeding.&nbsp;Breast-feeding should be discontinued if you are being treated with Dasatinib Krka.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>If you experience&nbsp;side effects&nbsp;such as dizziness and blurred vision, take special care when driving or using machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dasatinib Krka contains lactose and sodium<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Dasatinib Krka<\/h2>\n\n\n\n<p>Dasatinib Krka will only be prescribed to you by a doctor who has experience in the treatment of&nbsp;leukemia&nbsp;&nbsp;Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.&nbsp;Dasatinib Krka is prescribed for adults and children over 1 year of age.<br><\/p>\n\n\n\n<p>The recommended starting dose for adult patients with Ph + ALL is 140 mg once daily.<br><\/p>\n\n\n\n<p>Dosage&nbsp;one for children with Ph + ALL is based on body weight.&nbsp;Medicines containing dasatinib are taken orally once a day either as tablets or as a powder for&nbsp;oral suspension.&nbsp;Dasatinib tablets are not recommended for patients weighing less than 10 kg.&nbsp;Powders for&nbsp;oral&nbsp;suspension&nbsp;should be used in patients weighing less than 10 kg and in patients unable to swallow tablets.&nbsp;A dose change may be needed when switching between the formulations (tablets or powder for&nbsp;oral&nbsp;suspension&nbsp;), so do not switch from one formulation to another.&nbsp;Your doctor will determine the correct&nbsp;dose&nbsp;based on your weight, any&nbsp;side effects, and your response to the treatment.&nbsp;The starting dose of dasatinib in children is calculated based on body weight as follows:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"col\"><strong>Bodyweight (kg)&nbsp;<sup>a<\/sup><\/strong><\/th><th scope=\"col\"><strong>Daily&nbsp;dose&nbsp;(mg)<\/strong><\/th><\/tr><tr><td>10 &#8211; under 20 kg<\/td><td>40 mg<\/td><\/tr><tr><td>20 &#8211; under 30 kg<\/td><td>60 mg<\/td><\/tr><tr><td>30 &#8211; under 45 kg<\/td><td>70 mg<\/td><\/tr><tr><td>45 kg and over<\/td><td>100 mg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Tablets are not recommended for patients weighing less than 10 kg;&nbsp;powder for&nbsp;oral suspension&nbsp;should be used in these patients.<br><\/p>\n\n\n\n<p>There is no recommended&nbsp;dose&nbsp;of Dasatinib Krka for children under 1 year of age.<br><\/p>\n\n\n\n<p>Depending on how you respond to treatment, your doctor may recommend a higher or lower&nbsp;dose.&nbsp;The treatment can also be temporarily stopped.&nbsp;For higher or lower&nbsp;dosages, it may be necessary to combine tablets of different strengths.<br><\/p>\n\n\n\n<p><strong>How to take Dasatinib Krka<\/strong><\/p>\n\n\n\n<p>Take the tablets at the same time each day.&nbsp;Swallow the tablets whole.&nbsp;Do not crush, divide or chew them.&nbsp;Do not slurry the tablets.&nbsp;You can not be sure that you will get the right&nbsp;dose&nbsp;if you crush, divide, chew or slurry the tablets.&nbsp;Dasatinib Krka tablets can be taken with or without food.<br><\/p>\n\n\n\n<p><strong>Special instructions for handling Dasatinib Krka<\/strong><\/p>\n\n\n\n<p>Dasatinib Krka tablets are unlikely to break.&nbsp;Should this nevertheless occur, persons other than the patient should wear gloves when handling Dasatinib Krka.<br><\/p>\n\n\n\n<p><strong>How long to take Dasatinib Krka<\/strong><\/p>\n\n\n\n<p>Take Dasatinib Krka every day until your doctor tells you to stop.&nbsp;Make sure you take Dasatinib Krka for as long as it is prescribed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Dasatinib Krka then you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center immediately for risk assessment and advice.&nbsp;Medical care may be necessary.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Dasatinib Krka<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Take the next&nbsp;dose&nbsp;as usual according to&nbsp;prescription&nbsp;one.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>The following may be signs of serious side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have chest pain, difficulty breathing, cough, fainting<\/li><li>if you experience unexpected bleeding or bruising without being injured<\/li><li>if you notice blood in the vomit, stool, or urine, or if the stool is black<\/li><li>if you get signs of&nbsp;infection, such as fever or severe chills<\/li><li>if you get a fever, pain in the mouth or throat, blisters, or peeling of the skin and\/or mucous membranes<\/li><\/ul>\n\n\n\n<p><strong>Contact your doctor immediately<\/strong>&nbsp;if you notice any of the above.<br><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection&nbsp;(including&nbsp;infection&nbsp;caused by bacteria,&nbsp;viruses,&nbsp;and fungi)<\/li><li>Heart and lungs: shortness of breath<\/li><li>Digestive problems: diarrhea, nausea, vomiting<\/li><li>Skin, hair, eyes, general symptoms: rash, fever, swelling of the face, hands, and feet, headache, fatigue or weakness, bleeding<\/li><li>Pain: muscle aches (during or after treatment), abdominal pain (abdomen)<\/li><li>Tests may show: low&nbsp;platelet count, low&nbsp;white blood cell count&nbsp;(&nbsp;neutropenia&nbsp;),&nbsp;anemia, fluid around the lungs<br><\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infections:&nbsp;pneumonia, herpes virus infection (including&nbsp;cytomegalovirus&nbsp;&#8211;&nbsp;CMV&nbsp;), upper respiratory tract infection, a severe&nbsp;infection&nbsp;of the blood or&nbsp;tissues(including rare fatal cases)<\/li><li>Heart and lungs: palpitations, irregular heartbeat,&nbsp;heart failure, impaired heart function, high&nbsp;blood pressure, high&nbsp;blood pressure&nbsp;in the lungs, cough<\/li><li>Digestive problems: appetite disorders, taste disorders, flatulence or distended abdomen,&nbsp;inflammation&nbsp;of the colon, constipation, heartburn, cold sores, weight gain, weight loss, inflammation of the stomach<\/li><li>Skin, hair, eyes, general symptoms: tingling in the skin,&nbsp;itching, dry skin,&nbsp;acne,&nbsp;inflammation&nbsp;of the skin, persistent noise in the ears, hair loss, excessive sweating, vision problems (including blurred vision and vision change), dry eyes, bruising, depression, insomnia, hemorrhage, dizziness, bruising,&nbsp;anorexia&nbsp;(loss of appetite), drowsiness, generalized&nbsp;edema<\/li><li>Pain: Joint pain, muscle weakness, chest pain, pain around hands and feet, chills, stiffness in muscles and joints, muscle cramps<\/li><li>Tests may show: fluid around the heart, fluid in the lungs, irregular heartbeat, febrile&nbsp;neutropenia, bleeding in the gastrointestinal tract, high levels of&nbsp;uric acid in the blood<br><\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart and lungs: heart attack (sometimes fatal),&nbsp;inflammation&nbsp;of the pericardium, irregular heartbeat, chest pain due to reduced blood supply to the heart (angina), low&nbsp;blood pressure, constriction of the airways, which can cause breathing difficulties,&nbsp;asthma, increased&nbsp;blood pressure&nbsp;in the pulmonary&nbsp;artery&nbsp;s (blood vessels)<\/li><li>Digestive problems:&nbsp;inflammation&nbsp;of the pancreas,&nbsp;stomach ulcers,&nbsp;inflammation of the esophagus, swollen stomach (abdomen), ulcers in the rectum&nbsp;mucosa, difficulty swallowing,&nbsp;inflammation&nbsp;of the gallbladder, blocking the bile ducts,&nbsp;gastroesophageal reflux disease&nbsp;(a condition in which acid and other stomach contents come back up into the throat )<\/li><li>Skin, hair, eyes, general symptoms:&nbsp;allergic reaction&nbsp;including soreness, lumpy blush (anxiety), anxiety, confusion, mood swings, decreased sexual desire, fainting, tremors,&nbsp;inflammation&nbsp;of the eye that can cause redness and pain, a skin disease characterized by sore, red, sharply demarcated and raised skin spots with rapid onset of fever and elevated&nbsp;white blood cell count&nbsp;(&nbsp;neutrophil&nbsp;dermatosis&nbsp;), hearing loss, photosensitivity, visual impairment, increased tear flow, altered skin color,&nbsp;inflammation&nbsp;of the subcutaneous adipose tissue, wounds on the skin, blistering on the skin, nail problems, hand-foot syndrome,&nbsp;kidney failure, affected urination frequency, breast enlargement in men, menstrual disorders, general weakness and discomfort, low thyroid function, balance problems when walking,&nbsp;osteonecrosis&nbsp;(a condition in which skeletal bones die and collapse due to impaired blood supply), joint inflammation, any swelling of the body<\/li><li>Pain:&nbsp;inflammation&nbsp;of the blood vessels that can cause redness, tenderness and swelling, tendinitis (tendinitis)<\/li><li>Brain: memory loss<\/li><li>Tests may show: abnormal blood levels and possibly impaired kidney function caused by residues of the decaying&nbsp;tumor&nbsp;(tumor lysis syndrome), low levels of albumin in the blood, low levels of&nbsp;lymphocytes&nbsp;(a type of&nbsp;white blood cell&nbsp;) in the blood, high cholesterol levels, swollen&nbsp;lymph nodes, bleeding in the brain, irregularities in the electrical impulses to the heart, enlarged heart,&nbsp;inflammation of the liver,&nbsp;protein&nbsp;in the urine, elevated levels of creatinine phosphokinase (an&nbsp;enzyme&nbsp;found mainly in the heart, brain, and skeletal muscles), elevated levels of troponin (an&nbsp;enzyme found mainly in the heart and skeletal muscles), elevated gamma-glutamyltransferase (an&nbsp;enzyme&nbsp;found mainly in the liver)<br><\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart and lungs: enlarged upper ventricles, myocarditis, the combined effect of various conditions that block the blood supply to the heart (&nbsp;acute&nbsp;heart syndrome), cardiac arrest (blockage of blood flow from the heart), coronary heart disease,&nbsp;inflammation&nbsp;of the&nbsp;tissue&nbsp;covering the heart and lungs, blood clots, blood clots the lungs<\/li><li>Digestive problems: decreased absorption of important nutrients, such as&nbsp;protein, from the gastrointestinal tract, intestinal knots, anal fistula (an abnormal opening from the anus to the skin around the anus), impaired kidney function,&nbsp;diabetes<\/li><li>Skin, hair, eyes, general symptoms: convulsions,&nbsp;inflammation&nbsp;of the&nbsp;optic nerve which can cause a complete or partial loss of vision, blue-violet spots on the skin, abnormally high thyroid function,&nbsp;inflammation&nbsp;of the thyroid gland,&nbsp;ataxia&nbsp;(a condition associated with lack of muscular coordination), difficulty walking, miscarriage,&nbsp;inflammation&nbsp;of the blood vessels of the skin, skin fibrosis<\/li><li>Brain:&nbsp;stroke, temporary events of nervous system dysfunction caused by decreased blood flow, facial paralysis, dementia<\/li><li>Immune system: severe&nbsp;allergic reaction<\/li><li>Muscles, bones, and connective tissue: the delayed interconnection of the bone ends that form joints (epiphyses);&nbsp;slower or delayed growth<br><\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;that have been reported (affects an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammatory changes in the lungs<\/li><li>Bleeding in the stomach or intestines can lead to death<\/li><li>Recurrence (reactivation) of&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;when you have previously had&nbsp;hepatitis&nbsp;B (a liver infection)<\/li><li>A reaction with fever, blisters on the skin, and sores on the mucous membranes<\/li><li>Kidney disease with symptoms including&nbsp;edema&nbsp;and abnormal laboratory test results such as&nbsp;protein&nbsp;in the urine and low protein content in the blood.<\/li><li>Damage to blood vessels, so-called thrombotic microangiopathy (TMA), including decreased number of&nbsp;red blood cells, decreased number of&nbsp;platelets,&nbsp;and blood clot formation.<br><\/li><\/ul>\n\n\n\n<p>Your doctor will check if you have any of these&nbsp;side effects&nbsp;during your treatment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Dasatinib Krka<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister and the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is dasatinib.&nbsp;Each film-coated tablet contains 20 mg, 50 mg, 70 mg, 80 mg, 100 mg or 140 mg of dasatinib.<\/li><li>Other ingredients are Tablet core: lactose monohydrate;&nbsp;cellulose, microcrystalline;&nbsp;croscarmellose sodium;&nbsp;hydroxypropyl cellulose;&nbsp;magnesium stearate. <em>Film coating:<\/em>&nbsp;lactose monohydrate;&nbsp;hypromellose;&nbsp;titanium dioxide (E171);&nbsp;triacetin.&nbsp;(see section 2 \u201cDasatinib Krka contains&nbsp;lactose&nbsp;and sodium\u201d).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Dasatinib Krka 20 mg: The film-coated tablet is white to off-white, biconvex, round with a diameter of about 5.6 mm, with \u201cD7SB\u201d engraved on one side and \u201c20\u201d on the other side.<br><\/p>\n\n\n\n<p>Dasatinib Krka 50 mg: The film-coated tablet is white to off-white, biconvex, oval of approximately 11.0 mm in length and approximately 6.0 mm in width, with \u201cD7SB\u201d engraved on one side and \u201c50\u201d on the other.<br><\/p>\n\n\n\n<p>Dasatinib Krka 70 mg: The film-coated tablet is white to off-white, biconvex, round with a diameter of about 9.1 mm, with \u201cD7SB\u201d engraved on one side and \u201c70\u201d on the other side.<br><\/p>\n\n\n\n<p>Dasatinib Krka 80 mg: The film-coated tablet is white to off-white, biconvex, triangular with an approximate length of 10.4 mm and an approximate width of 10.6 mm, with \u201cD7SB\u201d engraved on one side and \u201c80\u201d on the other.<br><\/p>\n\n\n\n<p>Dasatinib Krka 100 mg: The film-coated tablet is white to off-white, biconvex, oval with approximately 15.1 mm in length and approximately 7.1 mm in width, with \u201cD7SB\u201d engraved on one side and \u201c100\u201d on the other side.<br><\/p>\n\n\n\n<p>Dasatinib Krka 140 mg: The film-coated tablet is white to off-white, biconvex, round with a diameter of about 11.7 mm, with \u201cD7SB\u201d engraved on one side and \u201c140\u201d on the other side.<br><\/p>\n\n\n\n<p>All strengths of Dasatinib Krka are available in cartons containing:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>30 or 60 film-coated tablets, in unperforated blisters.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Synthon Hispania SL, Castell\u00f3 1, Pol\u00edgono Las Salinas, 08830 Sant Boi de Llobregat (Barcelona), Spain<\/p>\n\n\n\n<p>Synthon BV, Microweg 22, 6545 CM Nijmegen, The Netherlands<\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p>KRKA-FARMA doo, V. Holjevca 20 \/ E, 10450 Jastrebarsko, Croatia<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This medicine is used to treat Philadelphia chromosome-positive (Ph +) acute lymphocytic leukemia (ALL) in adults who have not responded to previous treatment, as well as in adolescents and children at least 1 year old. Leukemia is a cancer of white blood cells. The white blood cells usually help the body fight infection. ALL is a form of leukemia in which the white blood cells called lymphocytes are formed too fast and live too long. Dasatinib Krka inhibits the growth of these leukemic cells. Ask your doctor if you are wondering how Dasatinib Krka works or why this medicine has been prescribed for you.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[6077,6097,6100,6101,6081,6079,2212,6080,6099,2211,6078,6098],"class_list":["post-7259","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-dasatinib","tag-dasatinib-krka","tag-dasatinib-krka-side-effects","tag-dasatinib-krka-tablet","tag-dasatinib-side-effects","tag-dasatinib-tablet","tag-medicine","tag-side-effects-of-dasatinib","tag-side-effects-of-dasatinib-krka","tag-tablets","tag-what-is-dasatinib","tag-what-is-dasatinib-krka"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7259","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7259"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7259\/revisions"}],"predecessor-version":[{"id":11146,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7259\/revisions\/11146"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7259"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7259"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}