\n\n500 mg, 1000 mg of powder for infusion solution
dacarbazine<\/p>\n\n\n\n
Dacarbazine belongs to a group of medicines called cytotoxic drugs. These drugs affect the growth of cancer cells.
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You have been prescribed Dacarbazine medac for the treatment of cancer:<\/p>\n\n\n\n
Dacarbazine medac can be used in combination with other cytotoxic drugs.<\/p>\n\n\n\n
Dacarbazine contained in Dacarbazine medac may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.
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Talk to your doctor or pharmacist before taking Dacarbazine medac.
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Before each treatment, you will be given blood samples to check that you have enough blood cells to be able to receive this medicine. Your liver and kidney function will also be checked.
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You should not be given a live vaccine if you are receiving Dacarbazine medac, as Dacarbazine medac may weaken your immune system and increase the likelihood of you getting a serious infection.
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You must not use foot mustache if you are being treated with Dacarbazine medac.<\/p>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
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The use of any other drug treatment without consulting your doctor is not recommended as there may be an interaction between Dacarbazine medac and other drugs.<\/p>\n\n\n\n
In particular, talk to your doctor or pharmacist if you are using or are being treated with any of the following:<\/p>\n\n\n\n
You must not be given a live vaccine if you are receiving Dacarbazine medac and for 3 months after stopping treatment with Dacarbazine medac. This is because Dacarbazine medac can weaken your immune system and increase the likelihood of you getting a serious infection.<\/p>\n\n\n\n
You can get a “killed” or inactivated vaccine if you receive Dacarbazine medac.<\/p>\n\n\n\n
You should not drink alcohol during chemotherapy.<\/p>\n\n\n\n
Dacarbazine medac should not be given if you are pregnant, think you may be pregnant, or are planning to have a baby.
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You must not breast-feed while you are being treated with Dacarbazine medac.
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During treatment with Dacarbazine medac, you must use an effective method of contraception. Men should continue to use contraception for at least 6 months after stopping treatment with Dacarbazine medac.
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If you are considering becoming pregnant or breast-feeding, you should first discuss this with your doctor.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
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Your ability to drive and use machines may be affected by central nervous system side effects (effects on the brain and nerves) or nausea or vomiting. However, you can drive and use machines between treatments with this medicine, as long as you do not feel dizzy or unsafe.
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This medicine is given to you under the supervision of a doctor who specializes in oncology (cancer treatment) or hematology (the study of blood diseases). You will be checked regularly during and after your treatment for any signs of side effects.
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Dacarbazine is a substance that is sensitive to light. The doctor or nurse who gives you this medicine will make sure that dacarbazine is protected from daylight during treatment.
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How much Dacarbazine medac will you get<\/strong><\/p>\n\n\n\n Your doctor will calculate the dose you should receive. This depends on the type of cancer you have and how far advanced it is, your body surface area (m\u00b2), the number of blood cells, and other cancer drugs or treatments you are receiving. The attending physician also determines individually how long this drug will be given to you. Your doctor may change the dose and how often the doses are given depending on your blood test results, your general condition, other treatments, and how you react to this medicine. If you have any further questions on the use of this product, ask your doctor, nurse, or pharmacist. Skin cancer (metastatic malignant melanoma )<\/em><\/strong><\/p>\n\n\n\n The usual dose is 200 – 250 mg per m\u00b2 body surface area, once daily. You can be given this dose 5 days in a row every 3 weeks. It is given as a quick injection into a vein or as a slow infusion into a vein that takes 15-30 minutes.<\/p>\n\n\n\n Alternatively, you can be given a larger dose of 850 mg per m\u00b2 body area every 3 weeks. This is given as a slow infusion into a vein. Cancer of the lymphatic tissue ( Hodgkin’s disease )<\/em><\/strong><\/p>\n\n\n\n The usual dose is 375 mg per month of body surface area, every 15 days. You will also be given medicines called doxorubicin, bleomycin, and vinblastine (this combination is called the ABVD regimen ). It will be given as a slow infusion into a vein. Cancer of muscles, fibrous tissue, blood vessels, or other supporting tissue in the body (soft tissue sarcoma)<\/em><\/strong><\/p>\n\n\n\n The usual dose is 250 mg per m3 of body surface area, once daily. You will receive this dose 5 days in a row, every 3 weeks. It is given as a slow infusion into a vein and takes 15-30 minutes. You will also be given medicines called doxorubicin (this combination is called the ADIC\u2011 regimen ). Patients with kidney or liver problems<\/strong><\/p>\n\n\n\n If you have either mild or moderate kidney or liver problems, you usually do not need to take a smaller amount of this medicine. If you have both kidney and liver problems, it takes longer for your body to excrete the medicine from your body. Your doctor may give you less of this medicine. Use for children<\/strong><\/p>\n\n\n\n Your doctor may not make any specific recommendations for the use of this medicine in children until more data become available.<\/p>\n\n\n\n If you have been given too much Dacarbazine medac it can lead to a severe decrease in the number of blood cells, This can lead to complete loss of bone marrow function. Any symptoms include signs of infection, bruising due to increased bleeding tendency, or fatigue. They may occur after 2 weeks. Contact your doctor, nurse, or Poison Information Center immediately if you think you have been given too much Dacarbazine medac.<\/p>\n\n\n\n The number of blood cells will be checked and supportive measures such as transfusions may be required. If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Your doctor will discuss these side effects with you and explain the risks and benefits of your treatment. Tell your doctor immediately if you notice any of the following:<\/strong><\/p>\n\n\n\n These are serious side effects. You may need urgent medical attention.<\/strong> Listed below are other side effects that may occur: Common<\/strong> (may affect up to 1 in 10 people)<\/p>\n\n\n\n The changes in the number of blood cells are dose-dependent and delayed. Often the lowest values \u200b\u200bare only reached after 3 to 4 weeks.<\/p>\n\n\n\n Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n Rare<\/strong> (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n If the drug is accidentally injected into the tissue around a vein, this can cause pain and lead to tissue damage. You may get one or more of these symptoms. If you get any side effects, talk to your doctor or pharmacist.<\/strong> Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the label and carton after \u201cEXP\u201d. The expiration date is the last day of the specified month. Do not store above 25 \u00b0 C. Keep the vial in the outer carton. Sensitive to light.<\/p>\n\n\n\n The shelf life under these conditions is 3 years. Prepared solution of Dacarbazine medac<\/em><\/strong><\/p>\n\n\n\n Newly prepared solutions of Dacarbazine medac are stable for 48 hours at 28 \u00b0 C when stored protected from light. From a microbiological point of view, the product should be used immediately. If not used immediately, in-use storage times and conditions before use are the responsibility of the user and would normally not be longer than 24 hours at 2 to 8 \u00b0 C, unless reconstitution has taken place under controlled and validated aseptic conditions. A prepared and further diluted solution of Dacarbazine medac<\/em><\/strong><\/p>\n\n\n\n A prepared and further diluted solution of Dacarbazine medac is stable for 24 hours at 28 \u00b0 C under light-proof storage in polyethylene containers and glass bottles, and for 2 hours at 25 \u00b0 C in polyethylene containers. From a microbiological point of view, the reconstituted and further diluted solution of Dacarbazine medac must be used immediately. Dacarbazine medac is for single use only.<\/p>\n\n\n\n Any contents that remain after use should be discarded by your doctor, as well as solutions whose appearance has visibly changed. The diluted infusion solution should be checked visually by your doctor and only clear solutions that are virtually free of particles should be used.<\/p>\n\n\n\n medac<\/p>\n\n\n\n Society for clinical<\/p>\n\n\n\n Special preparations mbH<\/p>\n\n\n\n Theater. 6<\/p>\n\n\n\n 22880 Wedel<\/p>\n\n\n\n Germany<\/p>\n\n\n\n Phone: +49 (0) 4103 8006-0<\/p>\n\n\n\n Fax: +49 (0) 4103 8006-100 This medicinal product is authorized under the European Economic Area under the names: <\/strong><\/p>\n\n\n\n Dacarbazine belongs to a group of medicines called cytotoxic drugs. These drugs affect the growth of cancer cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[6212,6217,6220,6219,6215,6214,6216,6221,6213,6218],"class_list":["post-7231","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-dacarbazine","tag-dacarbazine-medac","tag-dacarbazine-medac-powder","tag-dacarbazine-medac-side-effects","tag-dacarbazine-powder","tag-dacarbazine-side-effects","tag-side-effects-of-dacarbazine","tag-side-effects-of-dacarbazine-medac","tag-what-is-dacarbazine","tag-what-is-dacarbazine-medac"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7231"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7231\/revisions"}],"predecessor-version":[{"id":11177,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7231\/revisions\/11177"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7231"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7231"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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<\/p>\n\n\n\nIf you take more Dacarbazine medac then you should<\/h2>\n\n\n\n
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<\/p>\n\n\n\n4. Possible side effects <\/h2>\n\n\n\n
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<\/p>\n\n\n\n5. How to store Dacarbazine medac<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information <\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
<\/p>\n\n\n\nBelgium<\/td> DACARBAZINE MEDAC 500 mg \/ 1000 mg, powder for solution for infusionDACARBAZINE MEDAC 500 mg \/ 1000 mg, powder for perfusionsolutionDACARBAZINE MEDAC 500 mg \/ 1000 mg, powder for the preparation of an infusion solution<\/td><\/tr> Denmark<\/td> Dacarbazine medac 500 mg \/ 1000 mg, powder for solution for infusion<\/td><\/tr> Ireland<\/td> Dacarbazine medac 500 mg \/ 1000 mg, Powder for solution for infusion<\/td><\/tr> Netherlands<\/td> Dacarbazine medac 500 mg \/ 1000 mg, Powder for solution for infusion<\/td><\/tr> Portugal<\/td> Dacarbazine medac 500 mg \/ 1000 mg, Po for solution for perfusion<\/td><\/tr> Spain<\/td> Dacarbazine medac 500 mg \/ 1000 mg, Powder for perfusion solution<\/td><\/tr> UK<\/td> Dacarbazine medac 500 mg \/ 1000 mg, Powder for solution for infusion<\/td><\/tr> Germany<\/td> Detimedac 500 mg \/ 1000 mg, powder for the preparation of an infusion solution<\/td><\/tr> Austria<\/td> Dacarbazine medac 500 mg \/ 1000 mg, powder for the preparation of an infusion solution<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"