{"id":7204,"date":"2021-02-19T12:24:39","date_gmt":"2021-02-19T12:24:39","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7204"},"modified":"2021-05-28T12:20:14","modified_gmt":"2021-05-28T12:20:14","slug":"cystadrops","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/cystadrops\/","title":{"rendered":"Cystadrops &#8211; Cysteamine uses, dose and side effects"},"content":{"rendered":"\n<p> 3.8 mg\/ml&nbsp;eye drops, solution&nbsp;<br>Cysteamine (mercaptamine)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Cystadrops is and what it is used for<\/h2>\n\n\n\n<p><strong>What Cystadrops is<\/strong><\/p>\n\n\n\n<p>Cystadrops are&nbsp;eye drops&nbsp;that contain the active substance cysteamine (also called mercaptamine).<br><\/p>\n\n\n\n<p><strong>What it is used for<\/strong><\/p>\n\n\n\n<p>It is used to reduce the number of cystine crystals on the surface of the eye (cornea) in adults and children over 2 years who have cystinosis.<br><\/p>\n\n\n\n<p><strong>What is cystinosis<\/strong><\/p>\n\n\n\n<p>Cystinosis is an unusual, inherited disease in which the body cannot break down excess&nbsp;cystine&nbsp;(an&nbsp;amino acid&nbsp;), which leads to accumulations of cystine crystals in various organs (such as kidneys and eyes).&nbsp;Accumulations of crystals in the eye can lead to increased photosensitivity (&nbsp;photophobia&nbsp;), damage to the cornea (&nbsp;keratopathy&nbsp;), and impaired vision.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Cystadrops<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Cystadrops<\/h2>\n\n\n\n<p>If you are allergic to cysteamine or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Cystadrops.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Cystadrops<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Although the level of Cystadrops in your blood is negligible, you should be careful.<\/p>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may experience blurred vision for a few minutes after using Cystadrops.&nbsp;Do not drive or use machines until you see clearly again.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Cystadrops contain benzalkonium chloride<\/h2>\n\n\n\n<p>This medicine contains 5 micrograms of benzalkonium chloride per drop, equivalent to 0.1 mg\/ml.<\/p>\n\n\n\n<p>Benzalkonium chloride can be absorbed by soft contact lenses and can discolor the contact lenses.&nbsp;Remove contact lenses before using the medicine and wait at least 15 minutes before re-inserting the contact lenses.<\/p>\n\n\n\n<p>Benzalkonium chloride can be irritating to the eyes, especially if you have dry eyes or problems with the cornea (the clear membrane at the front of the eye).&nbsp;If you experience irritation, tingling, or pain in the eye after using the medicine, consult a doctor.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Cystadrops<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>Recommended&nbsp;dose<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is 1 drop in each eye, 4 times a day.<\/li><li>The recommended interval between dosing sessions is 4 hours (for example, you can take the eye drops at 8.00, 12.00, 16.00, and 20.00).<\/li><li>It is recommended that you take the last drop of the day at least 30 minutes before bedtime to avoid sticky eyes in the morning.<\/li><li>Dose&nbsp;one can be reduced gradually (to a minimum daily&nbsp;dose&nbsp;of 1 drop in each eye) by your doctor, depending on the results of the eye examination.<br><\/li><\/ul>\n\n\n\n<p>Use only eye drops (&nbsp;ocular&nbsp;use).<br><\/p>\n\n\n\n<p><strong>Step 1: Before using the bottle for the first time<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cystadrops must be allowed to reach room temperature before the first dose.&nbsp;This makes it easier to give the drops.<\/li><li>Before using the eye drops for the first time, write the date of opening in the field on the carton.<\/li><li>Wash your hands thoroughly to avoid contaminating the contents of the bottle with bacteria.<\/li><li>Remove the green protective cover (Fig. 1).<\/li><li>Remove the metal seal (Fig. 2).<\/li><li>Remove the gray stopper (Fig. 3) from the bottle.<\/li><li>Do not touch the opening of the bottle after removing the gray stopper.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20140802000021#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/ad8e978c-d17a-4017-8799-90bdd291e421\" alt=\"Figures 1,2 and 3\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Remove the drip tip from the package without touching the end to be attached to the bottle and attach the drip tip (Fig. 4) to the bottle.&nbsp;Do not remove the drip tip from the bottle.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20140802000021#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/246fbe1f-3fbd-4f4b-89f2-c20242e5e7a2\" alt=\"Figures 4 and 5\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Be careful not to loosen the small white sleeve (Fig. 5) located on top of the drip tip.<br><\/li><\/ul>\n\n\n\n<p><strong>Step 2: Before using the eye drops<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Check the opening date you entered on the carton.&nbsp;Cystadrops can be used for up to 7 days after opening.<\/li><li>Get the drip bottle and a mirror.<\/li><li>Wash your hands.<\/li><\/ul>\n\n\n\n<p><strong>Step 3: Use the eye drops<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hold the drip bottle between your thumb and fingers with the tip facing down.&nbsp;Move the drip bottle up and down to get the drops in the drip tip.<\/li><li>Unscrew the small white sleeve from the drip tip.<\/li><li>Tilt your head back.&nbsp;Pull the eyelid down with a cleaned finger so that a &#8220;pocket&#8221; is formed between the eyelid and the eye.&nbsp;The drop should be placed there (picture 6).<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20140802000021#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/8b314a0f-0d1d-42eb-83f9-f13bb24ec3c1\" alt=\"Figure 6\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Place the tip of the dropper bottle close to the eye.&nbsp;Use the mirror if it facilitates.<\/li><li><strong>Do not touch the eye, eyelid, area around the eye, or other surfaces with the drip tip<\/strong>.&nbsp;It can infect the drops.<\/li><li>Gently press the drop tip to obtain one drop of Cystadrops at a time. Be especially careful not to touch the tip of the drip tip with your fingers.<\/li><li>After using Cystadrops, place a finger in the corner of the eye near the nose (Fig. 7) and gently massage the upper eyelid to spread the eye drops over the eye.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20140802000021#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/97c82cc5-a4a5-4771-848a-f6895fa0d67c\" alt=\"Picture 7\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Remove excess medicine around the eyes with a damp napkin (Fig. 8), to avoid possible irritation.<\/li><li>Repeat step 3 for the other eye.<\/li><li>Put the small white sleeve back on the drip tip immediately after use.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20140802000021#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/8f69d033-e552-41cf-9d9a-d920fec34bb2\" alt=\"Picture 8\"\/><\/a><\/figure>\n\n\n\n<p><strong>Step 4: Store the eye drops after use<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Place the dropper bottle in the carton.<\/li><li>Store Cystadrops at room temperature (this facilitates the use of the drip tip).<\/li><li><strong>Discard 7 days after opening.<\/strong><br><\/li><\/ul>\n\n\n\n<p><strong>If a drop comes out of the eye<\/strong><\/p>\n\n\n\n<p>Please try again<strong>.<\/strong><br><\/p>\n\n\n\n<p><strong>If you are taking Cystadrops with other eye medicines<\/strong><\/p>\n\n\n\n<p>Be sure to wait at least 10 minutes between using Cystadrops and other eye medicines.&nbsp;Use eye ointment last.<br><\/p>\n\n\n\n<p><strong>If you wear soft contact lenses<\/strong><\/p>\n\n\n\n<p>Do not use the drops when you have contact lenses in. After using the drops, wait 15 minutes before putting the lenses back in.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Cystadrops then you should &nbsp;<\/h2>\n\n\n\n<p>If you use too many drops in the eyes, rinse your eyes, preferably with saline solution (otherwise with warm water).&nbsp;Do not drip in more drops until it is time for your next&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Cystadrops<\/h2>\n\n\n\n<p>Wait until it is time for the next supply and continue according to the set intervals.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for forgotten use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Cystadrops<\/h2>\n\n\n\n<p>Cystadrops must be used every day for the drug to work properly.&nbsp;If you stop using Cystadrops, the accumulation of cystine crystals in the eye (cornea) may increase and lead to photosensitivity (&nbsp;photophobia&nbsp;), damage to the cornea (&nbsp;keratopathy&nbsp;), and impaired vision.&nbsp;Therefore, talk to your doctor before stopping treatment.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>You can usually continue to use the drops unless the&nbsp;side effects&nbsp;are severe.&nbsp;If you are worried, talk to your doctor or pharmacist.&nbsp;Do not stop using Cystadrops without talking to your doctor.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<br><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect more than 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>eye pain<\/li><li>red eyes, itchy eyes, irritated eyes (burning sensation)<\/li><li>watery eyes<\/li><li>Tamsyn<\/li><li>discomfort where the drops have been used (mainly sticky eyes and sticky&nbsp;eyelashes&nbsp;), drug accumulation on the&nbsp;eyelashes, around the eyes<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>abnormal feeling in the eye, feeling that there is something in the eye<\/li><li>dry eyes<\/li><li>swollen eyelids<\/li><li>irritated eyelids<\/li><li>visual impairment<\/li><li>pain where the drops have been used<\/li><li>sty<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Cystadrops<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle label and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p><strong>Unopened packaging:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C)<\/li><li>Store the bottle in the outer carton.&nbsp;Sensitive to light.<\/li><\/ul>\n\n\n\n<p><strong>Opened packaging:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Write the date when you open the bottle in the field on the box.<\/li><li>Cystadrops can be used for up to 7 days after opening.<\/li><li>Close the dropper bottle tightly and store it in the outer carton.&nbsp;Sensitive to light.<\/li><li>Do not store above 25 \u00b0 C.<\/li><li>Store in a cold place.<\/li><li><strong>You must discard the dropper bottle 7 days after opening, even if it is not empty.&nbsp;<\/strong>Use a new bottle.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is cysteamine (mercaptamine), as hydrochloride.&nbsp;One ml of&nbsp;eye drops&nbsp;contains 3.8 mg of cysteamine.<\/li><li>The other ingredients are benzalkonium chloride (see section 2 for more information on &#8220;Cystadrops contains benzalkonium chloride&#8221;), disodium edetate, caramel sodium, citric acid monohydrate, sodium hydroxide,&nbsp;hydrochloric acid, and water for&nbsp;injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Cystadrops is a clear and viscous eye drop solution.<br><\/p>\n\n\n\n<p>Each package contains:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>1 amber glass bottle containing 5 ml&nbsp;eye drops.<\/li><li>1 drip tip for application.<\/li><\/ul>\n\n\n\n<p>Cystadrops is available in packs of 1 carton or a multi-pack of 4 cartons.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed in your country.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Record Rare Diseases<\/p>\n\n\n\n<p>Real Estate \u201cLe Wilson\u201d<\/p>\n\n\n\n<p>70 Avenue du G\u00e9n\u00e9ral de Gaulle<\/p>\n\n\n\n<p>92800 Puteaux<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><br><\/p>\n\n\n\n<p>Record Rare Diseases<\/p>\n\n\n\n<p>Real Estate \u201cLe Wilson\u201d<\/p>\n\n\n\n<p>70 Avenue du G\u00e9n\u00e9ral de Gaulle<\/p>\n\n\n\n<p>92800 Puteaux<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p>or<br><\/p>\n\n\n\n<p>Record Rare Diseases<\/p>\n\n\n\n<p>Eco River Parc<\/p>\n\n\n\n<p>30, rue des Peupliers<\/p>\n\n\n\n<p>F-92000 Nanterre<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Bulgaria<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58France<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>RecordatiTel: +32 2 46101 36Belgium \/ Belgium<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58France<\/td><td><strong>Hungary<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58Franciaorsz\u00e1g<\/td><\/tr><tr><td><strong>Germany<\/strong>Recordati Rare Diseases Germany GmbHTel: +49 731 140 554 0<\/td><td><strong>The Netherlands<\/strong>RecordatiTel: +32 2 46101 36Belgium<\/td><\/tr><tr><td><strong>Greece<\/strong>Record Rare Diseases:\u0397\u03bb: + 33 1 47 73 64 58.\u0391\u03bb\u03bb\u03af\u03b1<\/td><td><strong>Austria<\/strong>Recordati Rare Diseases Germany GmbHTel: +49 731 140 554 0Germany<\/td><\/tr><tr><td><strong>Spain<\/strong>Recordati Rare Diseases Spain SLUTel: + 34 91 659 28 90<\/td><td><strong>Poland<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58France<\/td><\/tr><tr><td><strong>France<\/strong>Record Rare DiseasesTel: + 33 (0) 1 47 73 64 58<\/td><td><strong>Portugal<\/strong>Jaba Recordati SATel: +351 21 432 95 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58French<\/td><td><strong>Romania<\/strong>Record Rare DiseasesTel: + 33 (0) 1 47 73 64 58France<\/td><\/tr><tr><td><strong>Ireland<\/strong>Record Rare Diseases+33 (0) 1 47 73 64 58France<\/td><td><strong>Slovenia<\/strong>Record Rare DiseasesTel: +33 (0) 1 47 73 64 58France<\/td><\/tr><tr><td><br>\n\n<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Cystadrops are eye drops that contain the active substance cysteamine (also called mercaptamine).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6255,6258,6257,6250,6253,6252,4501,6259,6254,6256,6251],"class_list":["post-7204","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-cystadrops","tag-cystadrops-eye-drops","tag-cystadrops-side-effects","tag-cysteamine","tag-cysteamine-eye-drops","tag-cysteamine-side-effects","tag-eye-drops","tag-side-effects-of-cystadrops","tag-side-effects-of-cysteamine","tag-what-is-cystadrops","tag-what-is-cysteamine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7204"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7204\/revisions"}],"predecessor-version":[{"id":11184,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7204\/revisions\/11184"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}