{"id":7132,"date":"2021-02-18T08:58:27","date_gmt":"2021-02-18T08:58:27","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7132"},"modified":"2021-06-01T07:48:27","modified_gmt":"2021-06-01T07:48:27","slug":"crinone-vaginal-gel","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/crinone-vaginal-gel\/","title":{"rendered":"Crinone Vaginal Gel &#8211; Progesterone uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n8%&nbsp;<br>Progesterone<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. WHAT CRINONE VAGINAL GEL IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<p>Crinone vaginal&nbsp;gel&nbsp;belongs to the drug group female sex hormone.&nbsp;Crinone vaginal&nbsp;gel&nbsp;is used as an adjunct to other treatments for&nbsp;infertility.<\/p>\n\n\n\n<p>Progesterone&nbsp;contained in Crinone may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. BEFORE YOU USE CRINONE VAGINAL GEL<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Crinone vaginal gel<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to&nbsp;progesterone&nbsp;or any of the other ingredients of Crinone&nbsp;vaginal gel<\/li><li>in case of bleeding from the abdomen whose cause has not been investigated<\/li><li>in&nbsp;acute&nbsp;porphyria&nbsp;(hereditary metabolic disorder)<\/li><li>if you have breast or genital cancer<\/li><li>if you have or have had a blood clot disease e.g.&nbsp;stroke<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with Crinone vaginal gel<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have irregular bleeding from the abdomen<\/li><li>if you have impaired liver function<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use of other medicines<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.&nbsp;You should not use Crinone vaginal&nbsp;gel&nbsp;with other medicines that are administered in the vagina.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<br><\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>Crinone vaginal&nbsp;gel&nbsp;can be used during the first trimester (first 3 months) of pregnancy.<br><\/p>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<p>Crinone vaginal&nbsp;gel&nbsp;should not be used if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>During treatment with Crinone vaginal&nbsp;gel, in some patients, the&nbsp;ability to&nbsp;react&nbsp;may be reduced.&nbsp;Fatigue can occur and caution should therefore be exercised when sharper attention is required, for example when driving a car and during precision work.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important information about some of the ingredients of Crinone vaginal gel<\/h2>\n\n\n\n<p>The preservative sorbic acid can cause local skin reactions (eg contact dermatitis).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. HOW TO USE CRINONE VAGINAL GEL<\/h2>\n\n\n\n<p>Always use Crinone&nbsp;vaginal&nbsp;gel&nbsp;exactly&nbsp;as&nbsp;your&nbsp;doctor&nbsp;has told&nbsp;you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>Instructions for use<\/strong><\/p>\n\n\n\n<p>Crinone vaginal&nbsp;gel is&nbsp;applied to the vagina directly from the specially designed closed applicator.&nbsp;Remove the applicator from the cover.&nbsp;NOTE: Do not remove the swivel closure yet.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>1.<\/td><td>Take a firm grip on the thicker part of the applicator.&nbsp;Shake the contents of the narrow section.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19991217000014#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>2.<\/td><td>Unscrew the closure and discard it.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19991217000014#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>3.<\/td><td>You should either sit or lie with your knees bent when inserting the applicator.&nbsp;The narrow part of the applicator should be inserted carefully and completely into the vagina.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19991217000014#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>4.<\/td><td>Press the thicker part of the applicator firmly so that the&nbsp;gelcomes loose.&nbsp;Remove the applicator and discard it.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19991217000014#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>5.<\/td><td>Crinone covers the lining of the vagina and causes&nbsp;progesterone&nbsp;to be&nbsp;released slowly.<\/td><th scope=\"row\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19991217000014#\" rel=\"noopener\"><\/a><\/th><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Crinone vaginal gel than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Crinone vaginal gel<\/h2>\n\n\n\n<p>If you forget to take Crinone vaginal&nbsp;gel&nbsp;one day, take this&nbsp;dose the&nbsp;next day and then continue as your doctor advised.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, Crinone vaginal&nbsp;gel&nbsp;can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><em>Common&nbsp;adverse&nbsp;s<\/em>&nbsp;(occurring in more than 1 in 100): fatigue, headache, vaginal discharge, and breast tenderness.<\/p>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(affects less than 1 user in 100): Bleeding disorders in the form of&nbsp;spotting&nbsp;(small bleeding) irritation at the application site and&nbsp;hypersensitivity reactionare usually in the form of skin rash.<\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. HOW TO STORE CRINONE VAGINALGEL<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;dat.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. FURTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;progesterone&nbsp;.&nbsp;Each&nbsp;dose&nbsp;of&nbsp;vaginal gel&nbsp;contains 90 mg of&nbsp;progesterone&nbsp;.<\/li><li>The other ingredients are&nbsp;glycerol&nbsp;, easy-flowing paraffin, hydrogenated palm oil glycerides, carbomer, polycarbophil, sorbic acid (&nbsp;preservative&nbsp;), sodium hydroxide, purified water<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>A disposable white polyethylene applicator with a closure that can be turned off.&nbsp;Each&nbsp;applicator&nbsp;contains 1.45 g of&nbsp;gel&nbsp;and dispenses 1.125 g of&nbsp;gel&nbsp;.&nbsp;Each&nbsp;applicator&nbsp;is packaged and wrapped in a paper \/ aluminum \/ polyethylene foil.<\/p>\n\n\n\n<p>Applicator&nbsp;being packaged in an outer carton box and contains:&nbsp;<br>6 or 15&nbsp;applicator&nbsp;s of Crinone 8%&nbsp;vaginal gel&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Merck AB&nbsp;<br>Box 3033<\/p>\n\n\n\n<p>169 03 Solna<\/p>\n\n\n\n<p>Tel: 08\u2013562 445 00<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Manufacturer<\/h2>\n\n\n\n<p>Central Pharma (Contract Packing) Ltd.&nbsp;<br>Caxton road&nbsp;<br>Bedford MK41 0XZ&nbsp;<br>United Kingdom<br><\/p>\n\n\n\n<p>Millmount Healthcare Limited<\/p>\n\n\n\n<p>Block-7, City North Business Campus<\/p>\n\n\n\n<p>Stamullen, Co.&nbsp;Meath, K32 YD60<\/p>\n\n\n\n<p>Ireland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Crinone vaginal gel belongs to the drug group female sex hormone. Crinone vaginal gel is used as an adjunct to other treatments for infertility.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6455,6458,6457,3558,6345,6454,6347,6459,6349,6456,6346],"class_list":["post-7132","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-crinone-vaginal-gel","tag-crinone-vaginal-gel-dose","tag-crinone-vaginal-gel-side-effects","tag-gel","tag-progesterone","tag-progesterone-gel","tag-progesterone-side-effects","tag-side-effects-of-crinone-vaginal-gel","tag-side-effects-of-progesterone","tag-what-is-crinone-vaginal-gel","tag-what-is-progesterone"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7132"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7132\/revisions"}],"predecessor-version":[{"id":11234,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7132\/revisions\/11234"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}