Administration<\/strong><\/p>\n\n\n\nThe tablets should be swallowed whole with a glass of water.<\/p>\n\n\n\n
If you take more Cozaar Comp \/ Cozaar Comp Forte then you should<\/h2>\n\n\n\n
In case of overdose, contact your doctor immediately so that care can be given immediately. Symptoms of overdose include a drop in blood pressure, palpitations, a slow pulse, changes in blood composition, and dehydration.<\/p>\n\n\n\n
If you forget to take Cozaar Comp \/ Cozaar Comp Forte<\/h2>\n\n\n\n
Try to take Cozaar Comp \/ Cozaar Comp Forte as prescribed. Do not take a double dose to make up for a forgotten dose, but take the next dose as usual.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
If you experience any of the following, stop taking Cozaar Comp \/ Cozaar Comp Forte and to talk to your doctor immediately or seek medical attention:
<\/p>\n\n\n\n
A severe allergic reaction (rash, itching, swelling of the face, lips, mouth, or throat, which can cause difficulty swallowing and breathing).
<\/p>\n\n\n\n
This is a serious but rare side effect, occurring in more than 1 in 10,000 and less than 1 in 1,000 patients. You may need emergency medical care or hospitalization.
<\/p>\n\n\n\n
The following side effects have been reported:
<\/p>\n\n\n\n
Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n- cough, upper respiratory tract infection, nasal congestion, sinusitis, sinus problems,<\/li>
- diarrhea, abdominal pain, nausea, indigestion,<\/li>
- muscle aches or cramps, leg pain, back pain,<\/li>
- insomnia, headache, dizziness,<\/li>
- weakness, fatigue, chest pain,<\/li>
- increased potassium levels (which may cause abnormal heart rhythms), decreased hemoglobin levels,<\/li>
- changes in renal function, including renal failure,<\/li>
- too low blood sugar (hypoglycemia).<\/li><\/ul>\n\n\n\n
Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n- anemia, red or brown skin spots (in some cases especially on the feet, legs, arms, and buttocks, with joint pain, swelling of the hands and feet, and stomach pain), bruising, decreased white blood cell count, coagulation problems, decreased platelet count,<\/li>
- loss of appetite, increased levels of uric acid or gout, increased blood sugar levels, electrolyte disturbances,<\/li>
- anxiety, nervousness, panic disorder (recurrent panic attacks), confusion, depression, altered dream patterns, sleep disorders, drowsiness, impaired memory,<\/li>
- numbness and tingling or similar sensations, pain in the extremities, tremors, migraines, fainting,<\/li>
- blurred vision, burning sensation in the eye, conjunctivitis, decreased visual acuity, yellowing,<\/li>
- ringing, buzzing, thunder or clicking in the ears, dizziness,<\/li>
- low blood pressure, which may be associated with posture (feeling dizzy or weak when standing up), angina (chest pain), irregular heartbeat, cerebrovascular event ( TIA, “mini-stroke”), heart attack, palpitations,<\/li>
- inflammation of blood vessels, which is often associated with skin rashes or bruising,<\/li>
- sore throat, shortness of breath, bronchitis, pneumonia, water in the lungs (causing difficulty breathing), nosebleeds, runny nose, nasal congestion,<\/li>
- constipation, difficult to treat constipation, flatulence, stomach irritation, stomach spasms, vomiting, dry mouth, inflammation of the salivary gland, toothache,<\/li>
- jaundice (yellowing of the whites of the eyes and skin), inflammation of the pancreas,<\/li>
- hives, itching, inflammation of the skin, rash, redness of the skin, photosensitivity, dry skin, flushing (heat sensation, redness of the skin), sweating, hair loss,<\/li>
- pain in arms, shoulders, hips, knees or other joints, joint swelling, stiffness, muscle weakness,<\/li>
- frequent urination including at night, renal impairment including renal inflammation, urinary tract infection, sugar in the urine,<\/li>
- decreased sexual desire, impotence,<\/li>
- facial swelling, local swelling ( edema ), fever.<\/li><\/ul>\n\n\n\n
Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n- hepatitis ( inflammation of the liver), abnormal liver function tests.<\/li><\/ul>\n\n\n\n
No known frequency (cannot be calculated from the available data):<\/em><\/p>\n\n\n\n- flu-like symptoms,<\/li>
- unexplained muscle pain with dark (tea-colored) urine ( rhabdomyolysis ),<\/li>
- low levels of sodium in the blood ( hyponatremia ),<\/li>
- general malaise,<\/li>
- taste change ( dysgeusia ),<\/li>
- skin and lip cancer (non-melanoma skin cancer),<\/li>
- impaired vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or acute narrow-angle glaucoma ).<\/li><\/ul>\n\n\n\n
Reporting of side effects<\/em><\/p>\n\n\n\nIf you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. Postal address<\/p>\n\n\n\n
5. How to store Cozaar Comp \/ Cozaar Comp Forte<\/h2>\n\n\n\n
Keep out of sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton after EXP. date. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Blister:<\/em> Do not store above 30 \u00b0 C. Store in the original package. Sensitive to light. Moisture sensitive.
<\/p>\n\n\n\nPlastic jar: Do not store above<\/em> 25 \u00b0 C. Store in the original package. Sensitive to light. Close the jar tightly. Moisture sensitive.
<\/p>\n\n\n\nMedicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances are losartan potassium and hydrochlorothiazide.
<\/p>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg contains the active substances 50 mg losartan potassium and 12.5 mg hydrochlorothiazide .<\/p>\n\n\n\n
Cozaar Comp 100 mg \/ 12.5 mg contains the active substances 100 mg losartan potassium and 12.5 mg hydrochlorothiazide .<\/p>\n\n\n\n
Cozaar Comp Forte 100 mg \/ 25 mg contains the active substances 100 mg losartan potassium and 25 mg hydrochlorothiazide .
<\/p>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg, Cozaar Comp 100 mg \/ 12.5 mg and Cozaar Comp Forte 100 mg \/ 25 mg contain the following excipients: microcrystalline cellulose (E460), lactose monohydrate , pregelatinised starch , magnesium stearate (E572), hydroxypropylcellulose ( E463) and hypromellose (E464).
<\/p>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg contains 4.24 mg (0.108 mEq) of potassium . Cozaar Comp 100 mg \/ 12.5 mg and Cozaar Comp Forte 100 mg \/ 25 mg contain 8.48 mg (0.216 mEq) of potassium .
<\/p>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg and Cozaar Comp Forte 100 mg \/ 25 mg also contain titanium dioxide (E171), quinoline yellow (E104) and carnauba wax (E903).
<\/p>\n\n\n\n
Cozaar Comp 100 mg \/ 12.5 mg also contains titanium dioxide (E171) and carnauba wax (E903).<\/p>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg is supplied as yellow, oval film-coated tablets marked 717 on one side and smooth or scored on the other. The notch is not intended for splitting the tablet.<\/p>\n\n\n\n
Cozaar Comp 100 mg \/ 12.5 mg is supplied as white, oval film-coated tablets marked 745 on one side and smooth on the other.<\/p>\n\n\n\n
Cozaar Comp Forte 100 mg \/ 25 mg is supplied as light yellow, oval film-coated tablets marked 747 on one side and smooth on the other.
<\/p>\n\n\n\n
Cozaar Comp \/ Cozaar Comp Forte is available in the following packages:<\/p>\n\n\n\n
Cozaar Comp 50 mg \/ 12.5 mg: PVC \/ PE \/ PVDC blister packs with aluminum closure in cartons containing 4, 7, 10, 14, 20, 28, 30, 50, 56, 84, 98 or 280 tablets tablets and single-dose packs for hospital use containing 28, 56 or 98 tablets. HDPE jar containing 100 tablets.
<\/p>\n\n\n\n
Cozaar Comp 100 mg \/ 12.5 mg: PVC \/ PE \/ PVDC blister packs with aluminum closure in cartons containing 14, 15, 28, 30, 50, 56, 84, 90, 98 or 280 tablets. HDPE jar containing 100 tablets.
<\/p>\n\n\n\n
Cozaar Comp Forte 100 mg \/ 25 mg: PVC \/ PE \/ PVDC blister packs with aluminum closure in cartons containing 7, 14, 28, 30, 50, 56, 84, 90, 98 or 280 tablets and single-dose packs for hospital use containing 28, 56 or 98 tablets. HDPE jar containing 100 tablets.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Merck Sharp & Dohme BV<\/p>\n\n\n\n
PO Box 581<\/p>\n\n\n\n
2003 PC Haarlem<\/p>\n\n\n\n
Netherlands
<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nMerck Sharp & Dohme BV<\/p>\n\n\n\n
PO Box 581<\/p>\n\n\n\n
2003 PC Haarlem<\/p>\n\n\n\n
Netherlands
<\/p>\n\n\n\n
or
<\/p>\n\n\n\n
Merck Sharp & Dohme Ltd<\/p>\n\n\n\n
Shotton Lane<\/p>\n\n\n\n
NE23 3JU Cramlington<\/p>\n\n\n\n
Northumberland<\/p>\n\n\n\n
UK
<\/p>\n\n\n\n
or
<\/p>\n\n\n\n
Schering-Plow Labo NV<\/p>\n\n\n\n
Industrial Park 30<\/p>\n\n\n\n
Heist-op-den-Berg, 2220<\/p>\n\n\n\n
Belgium
<\/p>\n\n\n\n
Information provided by:<\/strong><\/p>\n\n\n\nBox 45192<\/p>\n\n\n\n
104 30 Stockholm<\/p>\n\n\n\n
Tel: 077-570 04 88
<\/p>\n","protected":false},"excerpt":{"rendered":"
Cozaar Comp \/ Cozaar Comp Forte is a combination of an angiotensin II receptor antagonist ( losartan ) and a diuretic ( hydrochlorothiazide ). Angiotensin II is a body-specific substance that binds to receptors in blood vessels and causes them to constrict. This causes the blood pressure to rise. Losartan prevents the binding of angiotensin II to these receptors, which causes the blood vessels to dilate and the blood pressure to drop. Hydrochlorothiazide helps the kidneys get rid of more water and salt, which also lowers blood pressure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6507,6506,6509,6510,6501,6503,6504,6511,6505,6508,6502],"class_list":["post-7099","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-cozaar-comp","tag-cozaar-comp-forte","tag-cozaar-comp-forte-side-effects","tag-cozaar-comp-forte-tablet","tag-losartan-potassium","tag-losartan-potassium-side-effects","tag-losartan-potassium-tablet","tag-side-effects-of-cozaar-comp-forte","tag-side-effects-of-losartan-potassium","tag-what-is-cozaar-comp-forte","tag-what-is-losartan-potassium"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7099"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7099\/revisions"}],"predecessor-version":[{"id":11271,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7099\/revisions\/11271"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}