{"id":7092,"date":"2021-02-13T08:39:58","date_gmt":"2021-02-13T08:39:58","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7092"},"modified":"2021-06-01T10:18:29","modified_gmt":"2021-06-01T10:18:29","slug":"covid-%e2%80%91-19-astrazeneca-vaccine","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/covid-%e2%80%91-19-astrazeneca-vaccine\/","title":{"rendered":"COVID \u2011 19 AstraZeneca Vaccine uses, dose and side effects"},"content":{"rendered":"\n<p>\n\nVaccine covid-19&nbsp;injection&nbsp;,&nbsp;suspension&nbsp;<br>(ChAdOx1-S [recombinant])<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What COVID \u2011 19 Vaccine AstraZeneca is and what it is used for<\/h2>\n\n\n\n<p>COVID \u2011 19 Vaccine AstraZeneca is a vaccine used to prevent covid \u2011 19 caused by the&nbsp;SARS \u2011 CoV&nbsp;virus&nbsp;2&nbsp;virus.<br><\/p>\n\n\n\n<p>It is given to adults who are 18 years and older.<br><\/p>\n\n\n\n<p>The vaccine stimulates the body&#8217;s natural defense mechanisms (the immune system).&nbsp;The vaccine works by causing the body to produce protection (&nbsp;antibodies&nbsp;and specialized&nbsp;white blood cells&nbsp;) against the&nbsp;virus&nbsp;that causes covid \u2011 19, which provides protection against covid \u2011 19.&nbsp;None of the ingredients in this vaccine can cause covid \u2011 19.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you are given COVID \u2011 19 AstraZeneca Vaccine<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">The vaccine must not be given to you:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to the active substance or any of the other ingredients of this vaccine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before giving you COVID \u2011 19 Vaccine AstraZeneca:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have previously had a severe, life-threatening&nbsp;<strong>allergic<\/strong>&nbsp;reaction to another vaccine or if you have had an&nbsp;allergic reaction&nbsp;to the first&nbsp;injection&nbsp;one with COVID \u2011 19 Vaccine AstraZeneca;<\/li><li>if you have ever fainted after a needle injection;<\/li><li>if you have a high fever (above 38 \u00b0 C) or severe&nbsp;infection.&nbsp;However, you can get your vaccination if you have a mild fever or a mild upper respiratory tract infection such as&nbsp;a cold;<\/li><li>if you have problems with bleeding or bruising easily, or if you are taking&nbsp;anticoagulants&nbsp;(to prevent blood clots);<\/li><li>if your immune system is not working properly (immune deficiency) or if you are taking medicines that weaken the immune system (such as&nbsp;high-dose corticosteroids, so-called immunosuppressive drugs, or cancer drugs).<\/li><\/ul>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor, pharmacist, or nurse before giving you the vaccine.<br><\/p>\n\n\n\n<p>As with all vaccines, vaccination with 2&nbsp;doses&nbsp;of COVID \u2011 19 Vaccine AstraZeneca may not&nbsp;protect&nbsp;everyone who is vaccinated.&nbsp;It is also not known how long the protection lasts.<\/p>\n\n\n\n<p>There is currently limited data on the efficacy of COVID \u2011 19 Vaccine AstraZeneca in individuals 55 years of age and older.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>COVID \u2011 19 AstraZeneca vaccine is not recommended for children under 18 years of age.&nbsp;There are currently insufficient data available on the use of COVID \u2011 19 Vaccine AstraZeneca in children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and COVID \u2011 19 Vaccine AstraZeneca<\/h2>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines or vaccines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor, pharmacist, or nurse for advice before taking this vaccine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Some of the&nbsp;side effects&nbsp;of COVID \u2011 19 Vaccine AstraZeneca listed in section 4 (Possible&nbsp;side effects&nbsp;) may temporarily impair your ability to drive and use machines.&nbsp;If you feel unwell after vaccination, do not drive or use machines.&nbsp;Wait until any&nbsp;side effects&nbsp;from the vaccine have passed before driving or using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">COVID \u2011 19 Vaccine AstraZeneca contains sodium and alcohol (ethanol)<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per&nbsp;dose&nbsp;of 0,5 ml, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p>This medicine contains 2 mg of alcohol (&nbsp;ethanol&nbsp;) per&nbsp;dose&nbsp;of 0.5 ml.&nbsp;The low amount of alcohol in this medicine does not produce any noticeable effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How COVID \u2011 19 AstraZeneca Vaccine is given<\/h2>\n\n\n\n<p>COVID \u2011 19 Vaccine AstraZeneca is given as a&nbsp;0.5 ml&nbsp;injection&nbsp;into a muscle (usually in the upper arm).<br><\/p>\n\n\n\n<p>During and after each&nbsp;injection&nbsp;of the vaccine, your doctor, pharmacist or nurse will keep you under surveillance for about 15 minutes to check for signs of an&nbsp;allergic reaction.<\/p>\n\n\n\n<p><strong>You will receive 2&nbsp;injections&nbsp;<\/strong>of COVID-19 Vaccine AstraZeneca.&nbsp;The second&nbsp;injection&nbsp;can be given between 4 and 12 weeks after the first&nbsp;injection.&nbsp;You will be informed when to return for your second&nbsp;injection.<\/p>\n\n\n\n<p>When COVID \u2011 19 Vaccine AstraZeneca is given as the first&nbsp;injection, the second&nbsp;injection&nbsp;should also be with COVID \u2011 19 Vaccine AstraZeneca to complete the vaccination series.<\/p>\n\n\n\n<p><strong>If you miss a booked visit for your second&nbsp;injection&nbsp;of COVID \u2011 19 Vaccine AstraZeneca<\/strong><\/p>\n\n\n\n<p>If you miss a scheduled vaccination, ask your doctor, pharmacist, or nurse for advice.&nbsp;It is important that you return to receive your second&nbsp;injection&nbsp;of COVID \u2011 19 Vaccine AstraZeneca.&nbsp;If you miss a scheduled vaccination session, you may not be fully protected against covid \u2011 19.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this vaccine can cause&nbsp;side effects, although not everybody gets them.&nbsp;If you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor, pharmacist, or nurse.<br><\/p>\n\n\n\n<p>Seek&nbsp;medical&nbsp;attention&nbsp;<strong>immediately<\/strong>&nbsp;if you experience symptoms of a severe&nbsp;allergic reaction.&nbsp;Such reactions may involve one or more of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feeling faint or dizzy<\/li><li>changes in your heart rhythm<\/li><li>respiratory distress<\/li><li>hissing breathing<\/li><li>swelling of the lips, face, or throat<\/li><li>hives&nbsp;or skin rash<\/li><li>nausea or vomiting<\/li><li>abdominal pain.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur with COVID \u2011 19 Vaccine AstraZeneca:<br><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>tenderness, pain, warmth,&nbsp;itching,&nbsp;or bruising where&nbsp;the injection&nbsp;is given<\/li><li>fatigue or general malaise<\/li><li>chill or feel feverish<\/li><li>headache<\/li><li>nausea<\/li><li>joint pain or muscle aches<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling or&nbsp;redness&nbsp;where&nbsp;the injection&nbsp;is given<\/li><li>fever (&gt; 38 \u00b0 C)<\/li><li>vomiting or diarrhea<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feel sleepy or dizzy<\/li><li>decreased appetite<\/li><li>enlarged&nbsp;lymph nodes<\/li><li>excessive sweating, itchy skin, or rash<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store COVID-19 Vaccine AstraZeneca<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>A doctor, pharmacist, or nurse is responsible for storing the vaccine and for disposing of unused medicines correctly.&nbsp;The following information about storage, expiration date, use, and handling as well as disposal is intended for healthcare professionals.<br><\/p>\n\n\n\n<p>Do not use this vaccine after the expiry date which is stated on the label after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C \u2011 8 \u00b0 C).<\/p>\n\n\n\n<p>Do not freeze.<\/p>\n\n\n\n<p>Store the vials in the outer carton.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>From the time of opening the vial (first needle puncture) to&nbsp;administration, the vial can be stored for a maximum of 48 hours in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).&nbsp;Within this time period, the product can be stored and used at temperatures up to 30 \u00baC for up to 6 hours during a continuous period.&nbsp;After this time, the product should be discarded.&nbsp;Do not put it back in the refrigerator.<br><\/p>\n\n\n\n<p>Discard the vial if the&nbsp;suspension&nbsp;is discolored or contains visible particles.&nbsp;Do not shake.<br><\/p>\n\n\n\n<p>COVID-19 Vaccine AstraZeneca genetically modified&nbsp;organism&#8217;s (GMO).&nbsp;Any unused vaccine or&nbsp;waste material should be disposed of in accordance with local requirements for genetically modified&nbsp;organisms&nbsp;or biological hazardous waste.&nbsp;Spills should be disinfected with antiviral agents that are effective against adenovirus.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>One&nbsp;dose&nbsp;(0.5 ml) contains:<\/p>\n\n\n\n<p>Chimpanzee adenovirus encoding SARS-CoV-2 spike&nbsp;glycoprotein&nbsp;and ChAdOx1 \u2011 S&nbsp;<sup>*<\/sup>, at least 2.5 \u00d7 10&nbsp;<sup>8<\/sup>&nbsp;infectious devices<\/p>\n\n\n\n<p><sup>*<\/sup>&nbsp;Produced in genetically modified human embryonic kidney cells (HEK 293 \u2011 cells) and by&nbsp;recombinant DNA&nbsp;technology.<br><\/p>\n\n\n\n<p>This product contains genetically modified&nbsp;organisms&nbsp;(GMOs).<br><\/p>\n\n\n\n<p>The other ingredients are L \u2011 histidine, L \u2011 histidine hydrochloride monohydrate, magnesium chloride hexahydrate, Polysorbate 80 (E 433), sucrose, disodium edetate (dihydrate), water for injections (see section 2 \u201cCOVID-19 Vaccine AstraZeneca\u201d contains&nbsp;sodium&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Injection,&nbsp;suspension&nbsp;(&nbsp;for injection&nbsp;).&nbsp;Suspension&nbsp;one is colorless to light brown, clear to slightly opaque.<br><\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Multi-dose&nbsp;vial&nbsp;of 8&nbsp;doses&nbsp;(4 ml) with stopper (elastomer with aluminum seal) in a pack of 10 vials.&nbsp;Each&nbsp;vial&nbsp;contains 8&nbsp;doses&nbsp;of 0.5 ml.<\/li><li>Multi-dose&nbsp;vial&nbsp;of 10&nbsp;doses&nbsp;(5 ml) with a stopper (elastomer with aluminum seal) in a pack of 10 vials.&nbsp;Each&nbsp;vial&nbsp;contains 10&nbsp;doses&nbsp;of 0.5 ml.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>AstraZeneca AB<\/p>\n\n\n\n<p>SE-151 85 S\u00f6dert\u00e4lje<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>MedImmune Pharma BV, Nijmegen<\/p>\n\n\n\n<p>Lagelandseweg 78<\/p>\n\n\n\n<p>Nijmegen, 6545CG<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>AstraZeneca SA \/ NVTel: +32 2 808 53 06<\/td><td><strong>Lithuania<\/strong>UAB AstraZeneca LietuvaTel: +370 5 2141423<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Astrology Bulgaria BODYTel: +359 (2) 90 60 798<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>AstraZeneca SA \/ NVTel: +352 2 7863166<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>AstraZeneca Czech Republic sroTel: +420 228 882 054<\/td><td><strong>Hungary<\/strong>AstraZeneca Kft.Tel .: +3680 180 007<\/td><\/tr><tr><td><strong>Denmark<\/strong>AstraZeneca A \/ STel: +45 89 87 04 78<\/td><td><strong>Malta<\/strong>Associated Drug Co.&nbsp;Ltd.Tel: +356 2277 8134<\/td><\/tr><tr><td><strong>Germany<\/strong>AstraZeneca GmbHTel: 0800 22 88 660 (free of charge)<\/td><td><strong>The Netherlands<\/strong>AstraZeneca BVTel: 0800 70 11 (free)+31 79 363 2222<\/td><\/tr><tr><td><strong>Eesti<\/strong>AstraZenecaTel: +372 6549 600<\/td><td><strong>Norway<\/strong>AstraZeneca ASTel: +47 23 96 23 13<\/td><\/tr><tr><td><strong>Greece<\/strong>AstraZeneca AE:\u0397\u03bb: +30 211 1983792<\/td><td><strong>Austria<\/strong>AstraZeneca \u00d6sterreich GmbHTel: +43 1 711 31 0<\/td><\/tr><tr><td><strong>Spain<\/strong>AstraZeneca Pharmac\u00e9utica Spain, SATel: +34 93 220 20 14<\/td><td><strong>Poland<\/strong>AstraZeneca Pharma Poland Sp.&nbsp;z ooTel .: +48 22 104 60 80<\/td><\/tr><tr><td><strong>France<\/strong>AstraZenecaTel: 0 800 08 92 44 (green number)<\/td><td><strong>Portugal<\/strong>AstraZeneca Pharmaceutical Products, Lda.Tel: +351 30 880 17 68<\/td><\/tr><tr><td><strong>Croatia<\/strong>AstraZeneca dooTel: +385 1 4628 000<\/td><td><strong>Romania<\/strong>AstraZeneca Pharma SRLTel: +40 31 630 03 18<\/td><\/tr><tr><td><strong>Ireland<\/strong>AstraZeneca Pharmaceuticals (Ireland) DACTel: 1800 812456 (toll-free)<\/td><td><strong>Slovenia<\/strong>AstraZeneca UK LimitedTel: +386 1 60 03 197<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 519 3643<\/td><td><strong>Slovak Republic<\/strong>AstraZeneca AB, ozTel: +421 2 3321 5491<\/td><\/tr><tr><td><strong>Italy<\/strong>AstraZeneca SpATel: +39 02 9801 4221<\/td><td><strong>Finland \/ Finland<\/strong>AstraZeneca OyPuh \/ Tel: +358 94 24 55072<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>\u03a6\u03bb .\u03ba\u03c4\u03c9\u03c1 \u03a6\u03b1\u03c1\u00b5\u03b1\u03ba\u03b5\u03c4\u03b9\u03ba\u03ae \u03ae\u03c4\u03b4:\u0397\u03bb: +357 22090050<\/td><td>AstraZeneca ABTel: +46 3 130 11 892<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA AstraZeneca LatvijaTel: +371 68688132<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>AstraZeneca UK LtdTel: +44 8000 541 028<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>COVID \u2011 19 Vaccine AstraZeneca is a vaccine used to prevent covid \u2011 19 caused by the SARS \u2011 CoV virus 2 virus.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6612,6620,6621,6613,6614,6615,6616,6617,6619,2356,6618],"class_list":["post-7092","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-astrazeneca","tag-astrazeneca-dose","tag-astrazeneca-injection","tag-astrazeneca-vaccine","tag-covid-19-astrazeneca","tag-covid-19-vaccine","tag-covid19","tag-covid19-vaccine","tag-side-effects-of-astrazeneca","tag-vaccine","tag-what-is-astrazeneca"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7092","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7092"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7092\/revisions"}],"predecessor-version":[{"id":11270,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7092\/revisions\/11270"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}