{"id":7069,"date":"2021-02-11T10:38:52","date_gmt":"2021-02-11T10:38:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7069"},"modified":"2022-11-18T12:08:05","modified_gmt":"2022-11-18T12:08:05","slug":"cosmofer","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/cosmofer\/","title":{"rendered":"Cosmofer &#8211; Iron Dextran Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong> Cosmofer<\/strong> <strong>50 mg\/ml\u00a0solution for injection\/infusion,\u00a0iron (III)<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. WHAT COSMOFER IS AND WHAT IS COSMOFER USED FOR<\/h2>\n\n\n\n<p>It contains a combination of iron and <a href=\"https:\/\/amzn.to\/3XplYhY\" rel=\"noopener\">dextran<\/a> (a long chain of sugar molecules).\u00a0The type of iron found in it is the same as that found naturally in the body and is called\u00a0ferritin.\u00a0This means that you can inject it in high\u00a0doses.<\/p>\n\n\n\n<p>It is given at low iron values \u200b\u200b(sometimes called iron deficiency) if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You can not take iron preparations by mouth, for example, because you can not tolerate it<\/li><li>You have taken iron preparations by mouth and it has not had an effect<\/li><li>Your doctor thinks that a fast iron supply is needed to build up iron stores.<\/li><\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/amzn.to\/3XplYhY\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"320\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/11\/Cosmofer.jpg\" alt=\"Cosmofer\" class=\"wp-image-34382\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Cosmofer.jpg 500w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Cosmofer-300x192.jpg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/a><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. WHAT YOU SHOULD KNOW BEFORE YOU ARE GIVEN COSMOFER<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You Must Not Be Given Medicine:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/peanut-allergy-and-nut-allergy\/\">hypersensitive<\/a>) to the product or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have had severe allergic reactions to other injectable iron preparations<\/li><li>If you have&nbsp;anemia&nbsp;that is not caused by iron deficiency e.g.&nbsp;hemolytic anemia<\/li><li>If you have too much iron in your body or a disorder in your body&#8217;s use of iron<\/li><li>If you have a liver disease such as&nbsp;cirrhosis&nbsp;or&nbsp;hepatitis<\/li><li>In case of&nbsp;bacterial&nbsp;or viral infection<\/li><li>In kidney diseases such as&nbsp;acute&nbsp;renal failure<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before receiving using:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have previously been allergic to medicines<\/li><li>If you have <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sle\/\">systemic lupus erythematosus<\/a> (&nbsp;SLE&nbsp;)<\/li><li>If you have&nbsp;rheumatoid arthritis<\/li><li>If you have severe&nbsp;asthma,&nbsp;eczema,&nbsp;or other&nbsp;allergies&nbsp;you<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p><strong>Cosmofer injection <\/strong>is intended for adults only.&nbsp;It should not be given to children under 14.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Cosmofer<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you are taking or have recently taken any other medicines.&nbsp;This includes over-the-counter medications and herbal remedies.&nbsp;This is because it can affect the effects of other agents.&nbsp;Some other medicines can also affect the effect of Cosmofer.&nbsp;In particular, tell your doctor or nurse if you are taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vitamins&nbsp;and minerals<\/li><li>Agents containing iron and taken orally.&nbsp;Iron should not be taken by mouth until five days after the end of its treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p><strong>Cosmofer injection<\/strong> has not been tested on pregnant women.&nbsp;It is important that you tell your doctor if you are pregnant, think you may be pregnant, or are planning to have a baby.<\/p>\n\n\n\n<p>If you become pregnant during treatment, you must consult your doctor.&nbsp;Your doctor will decide if you should receive this medicine or not.<br><\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>If you are breastfeeding, talk to your doctor before giving this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Ask your doctor if you can drive and use machines after getting this medicine.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<p><strong>Blood tests<\/strong>&nbsp;<br>It can affect the results of certain blood tests, eg&nbsp;bilirubin,&nbsp;and&nbsp;calcium.&nbsp;Therefore, tell your doctor if blood samples are taken during treatment with it.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. HUR COSMOFER GES<\/h2>\n\n\n\n<p>Your doctor or nurse will give Iron Dextran via\u00a0intravenous\u00a0infusion\u00a0or slow\u00a0intravenous injection\u00a0or you can get it as an\u00a0injection\u00a0into a muscle.\u00a0Cosmofer is given in an environment where allergic reactions can be treated immediately.<\/p>\n\n\n\n<p>You will be observed for at least 30 minutes by your doctor or nurse after each&nbsp;administration.<br><\/p>\n\n\n\n<p>Dose&nbsp;one is based on iron values \u200b\u200b(&nbsp;hemoglobin&nbsp;) and your body weight.&nbsp;Your doctor will calculate the&nbsp;dose&nbsp;for you.&nbsp;This medicine is usually given two or three times a week.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Cosmofer Than You Should<\/h2>\n\n\n\n<p>A trained and educated person will guide you about <strong>Cosmofer uses<\/strong>.&nbsp;It is unlikely that you will get too much.&nbsp;They will control the&nbsp;dose&nbsp;so that not too much iron is stored in the body.&nbsp;If you suspect that you have been given too much medicine, talk to your doctor or nurse immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. POSSIBLE COSMOFER SIDE EFFECTS<\/h2>\n\n\n\n<p><strong>Cosmofer infusion side effects<\/strong><\/p>\n\n\n\n<p>Like all medicines, <strong><em>Cosmofer uses<\/em><\/strong> can cause&nbsp;side effects, although not everybody gets them.&nbsp;The following&nbsp;side effects&nbsp;may occur with this medicine:<\/p>\n\n\n\n<p><em><strong>Allergic reactions<\/strong><\/em><\/p>\n\n\n\n<p>Contact your doctor immediately if you experience any of the following signs and symptoms that may indicate <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A <strong>Cosmofer allergic reaction<\/strong><\/li><li>Shortness of breath<\/li><li>Hives<\/li><li>Swelling<\/li><li>Rash<\/li><li>Itching <\/li><li>Nausea and chills <\/li><li><a href=\"https:\/\/zeepedia.com\/diseases\/pain-in-the-chest\/\">Chest pain<\/a><\/li><\/ul>\n\n\n\n<p>which may be a sign of a potentially severe&nbsp;allergic reaction.&nbsp;called Kuoni&#8217;s syndrome.<br><\/p>\n\n\n\n<p><em>More severe <span style=\"text-decoration: underline;\">Cosmofer allergic reaction<\/span> may occur within a few minutes of starting treatment (affects less than 1 in 10,000 patients treated)<\/em>&nbsp;<br>Signs of <strong>Cosmofer side effects<\/strong> may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden difficulty breathing<\/li><li>Severe&nbsp;cardiovascular&nbsp;problems (&nbsp;cardiovascular&nbsp;collapse)<\/li><li>Deaths have been reported.<\/li><\/ul>\n\n\n\n<p>Delayed allergic reactions have also been reported.&nbsp;Such can occur a few hours up to four days after&nbsp;administration.&nbsp;Signs of this may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain in joints or muscles<\/li><li>Sometimes <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a><\/li><\/ul>\n\n\n\n<p>Contact your doctor if you notice such symptoms.<br><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;include<\/strong><\/p>\n\n\n\n<p><em>Uncommon <strong>cosmofer side effects<\/strong><\/em> <em>(affects less than 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abdominal pain and vomiting<\/li><li>Blurred vision<\/li><li>Feeling of warmth<\/li><li>Cramps<\/li><li>Numbness<\/li><\/ul>\n\n\n\n<p><em>Rare (affects less than 1 in 1,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Unconsciousness<\/li><li>Mental impact<\/li><li>Seizures<\/li><li>Dizziness<\/li><li>Restlessness<\/li><li>Fatigue<\/li><li>Low&nbsp;blood pressure<\/li><li>Angioedema&nbsp;(a type of severe&nbsp;allergic reaction, that may cause swelling)<\/li><li>Irregular&nbsp;heartbeat, fast&nbsp;heartbeat, chest pain<\/li><li>Diarrhea<\/li><li>Sweating<\/li><li>Tremors<\/li><\/ul>\n\n\n\n<p><em>Very rare (affects less than 1 patient in 10,000)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The low number of&nbsp;red blood cells&nbsp;(seen during blood tests)<\/li><li>Headache<\/li><li>Ant crawls<\/li><li>High&nbsp;blood pressure<\/li><li>Transient <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sudden-hearing-loss-sudden-deafness\/\">deafness<\/a><\/li><li>Palpitation<\/li><li>During pregnancy;&nbsp;It has been reported that the fetal heart rate may slow down<\/li><\/ul>\n\n\n\n<p><em>Not known<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Flu-like illness can occur for a few hours up to several days after&nbsp;injection&nbsp;and is usually characterized by symptoms such as high temperature, and aches and pains in muscles and joints<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that have been reported are that people with&nbsp;rheumatoid arthritis may have more <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">joint pain<\/a>.<br><\/p>\n\n\n\n<p><strong>Possible&nbsp;side effects&nbsp;after&nbsp;injection&nbsp;into a vein<\/strong>&nbsp;<br>If you get it injected into a vein, local reactions such as tenderness and swelling may occur.&nbsp;Inflammation&nbsp;of the vein&nbsp;has also been reported.<br><\/p>\n\n\n\n<p><strong>Possible&nbsp;side effects&nbsp;after&nbsp;injection&nbsp;into a muscle<\/strong>&nbsp;<br>When&nbsp;injecting&nbsp;Cosmofer into a muscle, the following may occur;&nbsp;discoloration of the skin, bleeding, sterile abscesses, tissue damage (tissue death or wasting), and pain.<\/p>\n\n\n\n<p>If any of the side effects gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or nurse.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. HOW TO STORE IT<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>No special storage instructions.&nbsp;Do not freeze.<\/li><li>Check the&nbsp;ampoule&nbsp;for&nbsp;precipitation&nbsp;or damage before use.&nbsp;Use only the&nbsp;ampoules with a&nbsp;homogeneous&nbsp;solution and without&nbsp;precipitation.<\/li><li>Healthcare professionals ensure that the product is stored and disposed of properly.<\/li><li>Do not use this&nbsp;medicine&nbsp;after the&nbsp;expiry date which is stated on the carton and&nbsp;ampoule&nbsp;after EXP:<\/li><li>The expiration date is the last day of the specified month.<\/li><li>Keep out of sight and reach of children.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. CONTENTS OF THE PACKAGING AND OTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is an iron (III) hydroxide dextran complex.<\/li><li>The other ingredients are water for injections, sodium hydroxide (&nbsp;pH&nbsp;regulator), and&nbsp;hydrochloric acid&nbsp;(&nbsp;pH&nbsp;regulator).<\/li><\/ul>\n\n\n\n<p>One 2 ml&nbsp;ampoule&nbsp;contains 100 mg of iron (III), one 5 ml&nbsp;ampoule&nbsp;contains 250 mg of iron (III) and one 10 ml&nbsp;ampoule&nbsp;contains 500 mg of iron (III).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>It is packaged in&nbsp;glass&nbsp;ampoules and the contents are brown.&nbsp;<\/li><li>The packages are available in sizes 5 x 2 ml, 10 x 2 ml, 10 x 5 ml, 2 x 10 ml, and 5 x 10 ml.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Pharmacosmos A \/ S&nbsp;<br>Roervangsvej 30&nbsp;<br>DK-4300 Holbaek&nbsp;<br>Denmark<\/p>\n\n\n\n<p>tel. +45 59 48 59 59<\/p>\n\n\n\n<p>fax +45 59 48 59 60<\/p>\n\n\n\n<p>email info@pharmacosmos.com<br><\/p>\n\n\n\n<p>This medicinal product is authorized under the European Economic Area under the names:<\/p>\n\n\n\n<p>Denmark: CosmoFer<\/p>\n\n\n\n<p>Estonia: CosmoFer<\/p>\n\n\n\n<p>Germany: CosmoFer<\/p>\n\n\n\n<p>Ireland: CosmoFer<\/p>\n\n\n\n<p>Latvia: CosmoFer<\/p>\n\n\n\n<p>Lithuania: CosmoFer<\/p>\n\n\n\n<p>Luxembourg: CosmoFer<\/p>\n\n\n\n<p>The Netherlands: CosmoFer<\/p>\n\n\n\n<p>Norway: Cosmofer<\/p>\n\n\n\n<p>Portugal: Cosmofer<\/p>\n\n\n\n<p>Spain: CosmoFer<\/p>\n\n\n\n<p>United Kingdom: CosmoFer<\/p>\n\n\n\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cosmofer is a combination of iron and dextran. The kind of iron found in Cosmofer is the same as that found certainly in the body and is known ferritin. This show that one can inject Cosmofer in high doses.<\/p>\n","protected":false},"author":2,"featured_media":34382,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2203,2200],"tags":[6552,6555,6554,2215,6547,6550,6549,2212,6556,6551,6553,6548],"class_list":["post-7069","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-c","category-medicines","tag-cosmofer","tag-cosmofer-injection","tag-cosmofer-side-effects","tag-injection","tag-iron-dextran","tag-iron-dextran-injection","tag-iron-dextran-side-effects","tag-medicine","tag-side-effects-of-cosmofer","tag-side-effects-of-iron-dextran","tag-what-is-cosmofer","tag-what-is-iron-dextran"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7069","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7069"}],"version-history":[{"count":46,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7069\/revisions"}],"predecessor-version":[{"id":34386,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7069\/revisions\/34386"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/34382"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7069"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7069"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7069"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}