{"id":7057,"date":"2021-02-11T10:24:58","date_gmt":"2021-02-11T10:24:58","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7057"},"modified":"2021-06-01T10:05:37","modified_gmt":"2021-06-01T10:05:37","slug":"corlentor","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/corlentor\/","title":{"rendered":"Corlentor &#8211; Ivabradine uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n5 mg, 7.5 mg&nbsp;film-coated tablets&nbsp;<br>ivabradine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Corlentor is and what it is used for<\/h2>\n\n\n\n<p>Corlentor (&nbsp;ivabradine&nbsp;) is a heart medicine used to treat<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Symptomatic stable&nbsp;angina pectoris&nbsp;(which causes chest pain) in adult patients whose&nbsp;heart rate&nbsp;is above or equal to 70 beats per minute.&nbsp;It is used in adult patients who are intolerant or unable to use&nbsp;beta-blockers.&nbsp;It is also used in combination with&nbsp;beta-blockers&nbsp;in adult patients whose condition cannot be completely controlled with&nbsp;beta-blockers&nbsp;alone.<\/li><li>Chronic&nbsp;heart failure&nbsp;in adult patients whose&nbsp;heart rate&nbsp;is above or equal to 75 beats per minute.&nbsp;It is used in combination with standard treatment, including treatment with&nbsp;beta-blockers&nbsp;or when&nbsp;beta-blockers&nbsp;must not be used or not tolerated.<\/li><\/ul>\n\n\n\n<p><strong><em>Stable&nbsp;angina pectoris&nbsp;(commonly referred to as &#8220;angina&#8221;):<\/em><\/strong><\/p>\n\n\n\n<p>Stable angina is a heart disease that occurs when the heart does not get enough oxygen.&nbsp;It usually occurs at the age of 40-50 years.&nbsp;The most common symptom of angina is chest pain or discomfort.&nbsp;It is more common for angina to occur when the heart beats faster in situations such as exertion, emotion, cold, or after a meal.&nbsp;The increase in heart rate can cause chest pain in people who suffer from angina.<br><\/p>\n\n\n\n<p><em>About&nbsp;chronic&nbsp;heart failure:<\/em><\/p>\n\n\n\n<p>Chronic&nbsp;heart failure&nbsp;is a heart disease that occurs when your heart cannot pump enough blood to the rest of your body.&nbsp;The most common symptoms of&nbsp;heart failure shortness of breath, fatigue, fatigue, and swollen ankles.<br><\/p>\n\n\n\n<p><strong><em>How does Corlentor work?<\/em><\/strong><\/p>\n\n\n\n<p>Corlentor works mainly by lowering&nbsp;heart rate&nbsp;by a few beats per minute.&nbsp;This reduces the heart&#8217;s oxygen needs, especially in situations where an angina attack is likely to occur.&nbsp;In this way, Corlentor helps control and reduce the number of angina attacks.<\/p>\n\n\n\n<p>In addition, because elevated&nbsp;heart rate&nbsp;adversely affects heart function and life expectancy in patients with&nbsp;chronic&nbsp;heart failure, the specific heart rate lowering effect of&nbsp;ivabradine helps&nbsp;to improve heart function and life expectancy in these patients.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Corlentor<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Corlentor<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;ivabradine&nbsp;or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if your resting heart rate before treatment is too low (less than 70 beats per minute)<\/li><li>if you suffer from&nbsp;cardiogenic&nbsp;shock&nbsp;(a heart condition that is treated in a hospital)<\/li><li>if you have arrhythmias<\/li><li>if you have a heart attack<\/li><li>if you have very low&nbsp;blood pressure<\/li><li>if you have&nbsp;unstable angina&nbsp;(a serious condition where the chest pain is very common and occurs with or without exertion)<\/li><li>if you have&nbsp;heart failure&nbsp;that has recently gotten worse<\/li><li>if your heart rhythm is exclusively maintained by a pacemaker<\/li><li>if you have severe liver problems<\/li><li>if using drugs to treat fungal infections (such as&nbsp;ketoconazole, itraconazole), macrolide antibiotics (such as josamycin, clarithromycin, telithromycin or erythromycin is given orally) or drugs against&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;s (such as nelfinavir, ritonavir) or nefazodone (medicine for the treatment of depression) or&nbsp;diltiazem, verapamil (used to treat high&nbsp;blood pressure&nbsp;or&nbsp;angina pectoris&nbsp;)<\/li><li>if you are a woman of childbearing potential and do not use a safe method of contraception<\/li><li>if you are pregnant or trying to become pregnant<\/li><li>if you are breast-feeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Corlentor<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have arrhythmia (such as irregular heartbeat, palpitations, increased chest pain) or persistent&nbsp;heart fibrillation&nbsp;(a type of irregular heartbeat), or an abnormal&nbsp;electrocardiogram&nbsp;(&nbsp;ECG&nbsp;), called &#8220;long&nbsp;QT&nbsp;syndrome&#8221;.<\/li><li>if you have symptoms such as fatigue, dizziness, or shortness of breath (this may mean that the heart slows down too much)<\/li><li>if you suffer from symptoms of&nbsp;atrial fibrillation&nbsp;(unusually high resting heart rate (over 110 beats per minute) or irregular resting heart rate for no apparent reason, making it difficult to measure)<\/li><li>if you have had a recent&nbsp;stroke&nbsp;(stroke)<\/li><li>if you suffer from a low&nbsp;blood pressure&nbsp;of mild or moderate severity<\/li><li>if your&nbsp;blood pressure is&nbsp;not completely controlled, especially after changes in your blood pressure-lowering treatment<\/li><li>if you suffer from severe&nbsp;heart failure&nbsp;or&nbsp;heart failure&nbsp;with abnormal&nbsp;ECG&nbsp;called &#8220;branch block&#8221;<\/li><li>if you have&nbsp;chronic&nbsp;retinal disease<\/li><li>if you have moderate liver problems<\/li><li>if you have severe kidney problems.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you, talk to your doctor immediately before or when you take Corlentor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Corlentor should not be given to children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Corlentor<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>It is important to tell your doctor if you are taking any of the following medicines, as a dose adjustment of Corlentor or follow-up may be necessary:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fluconazole&nbsp;(an&nbsp;antifungal&nbsp;)<\/li><li>rifampicin (&nbsp;antibiotic&nbsp;)<\/li><li>barbiturates&nbsp;(for insomnia or&nbsp;epilepsy&nbsp;)<\/li><li>phenytoin&nbsp;(for&nbsp;epilepsy&nbsp;)<\/li><li><em>Hypericum<\/em> perforatum&nbsp;or&nbsp;St. John&#8217;s wort&nbsp;(a natural remedy for depression)<\/li><li>QT-prolonging medicines to treat either heart rhythm disorders or other conditions:<ul><li>quinidine,&nbsp;disopyramide, ibutilide, sotalol,&nbsp;amiodarone&nbsp;(for&nbsp;cardiac arrhythmias&nbsp;)<\/li><li>bepridil (against&nbsp;angina pectoris&nbsp;)<\/li><li>certain medicines for anxiety, schizophrenia, or other&nbsp;psychoses&nbsp;(such as pimozide, ziprasidone, sertindole)<\/li><li>malaria drugs (such as mefloquine and halofantrine)<\/li><li>intravenous&nbsp;erythromycin (an&nbsp;antibiotic&nbsp;)<\/li><li>pentamidine (antiparasitic agent)<\/li><li>cisapride (for acid reflux)<\/li><\/ul><\/li><li>Certain types of&nbsp;diuretics&nbsp;can cause a decrease in potassium levels in the blood, such as&nbsp;furosemide,&nbsp;hydrochlorothiazide, indapamide (used to treat&nbsp;edema, high&nbsp;blood pressure&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Corlentor with food and drink<\/h2>\n\n\n\n<p>Avoid grapefruit juice during treatment with Corlentor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Do not use Corlentor if you are pregnant or planning to become pregnant (see &#8216;Do not take Corlentor&#8217;).<\/p>\n\n\n\n<p>Talk to your doctor if you are pregnant and have used Corlentor.<\/p>\n\n\n\n<p>Do not use Corlentor if you can get pregnant unless you use a safe method of contraception (see &#8220;Do not take Corlentor&#8221;).<\/p>\n\n\n\n<p>Do not use Corlentor if you are breast-feeding (see &#8220;Do not take Corlentor&#8221;).&nbsp;Talk to your doctor if you are breast-feeding or plan to start breast-feeding as breast-feeding should be stopped if you are using Corlentor.<\/p>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Corlentor can cause short-term light phenomena (a temporary increase in light intensity in the&nbsp;field of view, see &#8220;Possible side effects&#8221;).&nbsp;If you get this, be careful with driving and using machines when there may be sudden changes in light intensity, especially when driving at night.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Corlentor contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Corlentor<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Corlentor should be taken with meals.<br><\/p>\n\n\n\n<p><em>If you are being treated for stable&nbsp;angina pectoris<\/em><\/p>\n\n\n\n<p>The starting dose should not exceed one Corlentor 5 mg tablet twice daily.&nbsp;If you still have angina symptoms and have tolerated&nbsp;dose&nbsp;one of 5 mg twice daily,&nbsp;dose&nbsp;one may be increased.&nbsp;The maintenance dose should not exceed 7.5 mg twice daily.&nbsp;Your doctor will prescribe the right&nbsp;dose&nbsp;for you.&nbsp;The usual&nbsp;dose&nbsp;is one tablet in the morning and one tablet in the evening.&nbsp;In some cases (eg if you are older), your doctor may prescribe half a&nbsp;dose of&nbsp;one, ie half a tablet of Corlentor 5 mg (equivalent to 2.5 mg of&nbsp;ivabradine&nbsp;) in the morning and half a 5 mg tablet in the evening.<br><\/p>\n\n\n\n<p><em>If you are being treated for&nbsp;chronic&nbsp;heart failure<\/em><\/p>\n\n\n\n<p>The usual recommended starting dose is one tablet of Corlentor 5 mg twice daily, which can be increased to a tablet of Corlentor 7.5 mg twice daily if needed.&nbsp;Your doctor will assess which&nbsp;dose&nbsp;is right for you.&nbsp;The usual&nbsp;dose&nbsp;is one tablet in the morning and one tablet in the evening.&nbsp;In some cases (eg if you are older), your doctor may prescribe half a&nbsp;dose of&nbsp;one, ie half a Corlentor 5 mg tablet (equivalent to 2.5 mg&nbsp;ivabradine&nbsp;) in the morning and half a 5 mg tablet in the evening.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Corlentor then you should<\/h2>\n\n\n\n<p>A high&nbsp;dose of&nbsp;Corlentor can make you feel short of breath or tired because your heart is slowing down too much.&nbsp;Contact your doctor immediately if this happens.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Corlentor<\/h2>\n\n\n\n<p>Take the next&nbsp;dose&nbsp;at the usual time if you forget to take Corlentor.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<p>The calendar on the tablet blister should help you remember when you last took a Corlentor tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Corlentor<\/h2>\n\n\n\n<p>As treatment for angina (angina) or&nbsp;chronic&nbsp;heart failure is&nbsp;usually lifelong, you should consult your doctor before stopping treatment with this product.<br><\/p>\n\n\n\n<p>If you have the impression that the effect of Corlentor is too strong or too weak, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>The frequency of possible&nbsp;side effects is&nbsp;defined below according to the following system:<\/p>\n\n\n\n<p>very common: may affect more than 1 in 10 people<\/p>\n\n\n\n<p>common: may affect up to 1 in 10 people<\/p>\n\n\n\n<p>uncommon: may affect up to 1 in 100 people<\/p>\n\n\n\n<p>rare: may affect up to 1 in 1,000 people<\/p>\n\n\n\n<p>very rare: may affect up to 1 in 10,000 people<\/p>\n\n\n\n<p>no known frequency: can not be calculated from the available data<br><\/p>\n\n\n\n<p>The most common&nbsp;side effects&nbsp;with this medicine are dose-dependent and related to its mechanism of action:<\/p>\n\n\n\n<p><em>Very common:<\/em><\/p>\n\n\n\n<p>Light phenomena in the&nbsp;field of view&nbsp;(short moments with increased light intensity, usually caused by sudden changes in light conditions).&nbsp;They can also be described as a light ring, colored flashes, image resolution, or multiple images.&nbsp;They usually appear within the first two months of treatment, after which they may appear and disappear repeatedly during or after treatment.<br><\/p>\n\n\n\n<p><em>Usual:<\/em><\/p>\n\n\n\n<p>Impact on the work of the heart (symptoms are slow&nbsp;pulse&nbsp;).&nbsp;They occur mainly within the first 2 to 3 months after the start of treatment.<br><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have also been reported:<br><\/p>\n\n\n\n<p><em>Usual:<\/em><\/p>\n\n\n\n<p>Irregular, rapid contraction of the heart, abnormal perception of the heartbeat, uncontrolled&nbsp;blood pressure, headache, dizziness, and blurred vision (blurred vision).<br><\/p>\n\n\n\n<p><em>Uncommon:<\/em><\/p>\n\n\n\n<p>Palpitations and extra beats, nausea, constipation, diarrhea, abdominal pain, dizziness, difficulty breathing (&nbsp;dyspnea&nbsp;), muscle spasms, changes in laboratory parameters: high levels of&nbsp;uric acid&nbsp;in the blood, increase in&nbsp;eosinophil&nbsp;s (a type of&nbsp;white blood cell&nbsp;) and elevated levels&nbsp;of creatinine&nbsp;in the blood ( a breakdown product from the muscles), skin rash,&nbsp;angioedema&nbsp;(such as swelling of the face, tongue or throat, difficulty breathing or swallowing), low&nbsp;blood pressure, fainting, feeling tired, feeling weak, abnormal&nbsp;ECG&nbsp;heart pattern, double vision, impaired vision.<br><\/p>\n\n\n\n<p><em>Rare:<\/em><\/p>\n\n\n\n<p>Hives,&nbsp;itching, reddening of the skin, feeling sick.<br><\/p>\n\n\n\n<p><em>Very rare:<\/em><\/p>\n\n\n\n<p>Irregular heartbeats.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Corlentor<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is&nbsp;ivabradine&nbsp;(as hydrochloride)<\/p>\n\n\n\n<p>Corlentor 5 mg: one film-coated tablet contains 5 mg&nbsp;ivabradine&nbsp;(equivalent to 5.390 mg&nbsp;ivabradine&nbsp;as hydrochloride).<\/p>\n\n\n\n<p>Corlentor 7.5 mg: one film-coated tablet contains 7.5 mg&nbsp;ivabradine&nbsp;(equivalent to 8.085 mg&nbsp;ivabradine&nbsp;as hydrochloride).<\/p>\n\n\n\n<p>The other ingredients of the tablet core are&nbsp;lactose monohydrate, magnesium stearate (E 470 B), maize starch, maltodextrin, anhydrous&nbsp;colloidal&nbsp;silica (E 551), and in the film coating: hypromellose (E 464), titanium dioxide (E 171), macrogol&nbsp;E 422,&nbsp;glycerol&nbsp;), magnesium stearate (E 470 B), yellow iron oxide (E 172), red iron oxide (E 172).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20040607009420#\" rel=\"noopener\"><\/a>Corlentor 5 mg tablets are salmon-colored, oblong, film-coated tablets, scored on both sides, debossed with \u201c5\u201d on one side and&nbsp;on the other.<\/td><\/tr><tr><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20040607009420#\" rel=\"noopener\"><\/a>Corlentor 7.5 mg tablets are salmon-colored, triangular, film-coated tablets debossed with \u201c7.5\u201d on one side and&nbsp;on the other.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The tablets are available in&nbsp;calendar&nbsp;packs (Aluminum \/ PVC blisters) with 14, 28, 56, 84, 98, 100 or 112 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Servier Laboratories Servier<\/p>\n\n\n\n<p>50, rue Carnot<\/p>\n\n\n\n<p>92284 Suresnes cedex- France<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>The Laboratories Servier Industrie<\/p>\n\n\n\n<p>905 route de Saran<\/p>\n\n\n\n<p>45520 Judy &#8211; France<br><\/p>\n\n\n\n<p>Servier (Ireland) Industries Ltd<\/p>\n\n\n\n<p>Gorey Road<\/p>\n\n\n\n<p>Arklow &#8211; Co.&nbsp;Wicklow &#8211; Ireland<br><\/p>\n\n\n\n<p>Przedsiebiorstwo Farmaceutyczne ANPHARM SA<\/p>\n\n\n\n<p>ul.&nbsp;Annopol 6B &#8211; 03-236 Warsaw &#8211; Poland<br><\/p>\n\n\n\n<p>Servier Laboratorios, SL<\/p>\n\n\n\n<p>Avda.&nbsp;de los Madro\u00f1os, 33<\/p>\n\n\n\n<p>28043 Madrid<\/p>\n\n\n\n<p>Spain<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine: Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>SA Servier Benelux NVTel: +32 (0) 2 529 43 11<\/td><td><strong>Lithuania<\/strong>UAB &#8220;SERVIER PHARMA&#8221;Tel: +370 (5) 2 63 86 28<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>\u0415\u041e\u041e\u0414 Medical ServiceTel: +359 2 921 57 00<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>SA Servier Benelux NVTel: +32 (0) 2 529 43 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Servier sroTel: +420 222 118 111<\/td><td><strong>Hungary<\/strong>Servier Hungaria Kft.Tel .: + 36 1 238 77 99<\/td><\/tr><tr><td><strong>Denmark<\/strong>Servier Danmark A \/ STel: +45 36 44 22 60<\/td><td><strong>Malta<\/strong>VJ Salomone Pharma Ltd&nbsp;Tel: + 356 21 22 01 74<\/td><\/tr><tr><td><strong>Germany<\/strong>Servier Deutschland GmbHTel: +49 (0) 89 57095 01<\/td><td><strong>The Netherlands<\/strong>Servier Nederland Farma BVTel: +31 (0) 71 5246700<\/td><\/tr><tr><td><strong>Eesti<\/strong>Servier Laboratories O\u00dcTel: + 372 664 5040<\/td><td><strong>Norway<\/strong>Servier Danmark A \/ STel: +45 36 44 22 60<\/td><\/tr><tr><td><strong>Greece<\/strong>\u0395\u03a0\u0395 \u0395\u039b\u039b\u0391\u03a3 \u03a6\u0391\u03a1\u039c\u0391\u039a\u0395\u03a5\u03a4\u0399\u039a\u0397 \u0395\u03a0\u0395:\u0397\u03bb: +30 210 939 1000<\/td><td><strong>Austria<\/strong>Servier Austria GmbHTel: +43 (1) 524 39 99<\/td><\/tr><tr><td><strong>Spain<\/strong>DANVAL SATel: +34 91 748 96 30<\/td><td><strong>Poland<\/strong>Servier Polska SP.&nbsp;Z OOTel .: + 48 (0) 22 594 90 00<\/td><\/tr><tr><td><strong>France<\/strong>Servier Laboratories ServierTel: +33 (0) 1 55 72 60 00<\/td><td><strong>Portugal<\/strong>Servier Portugal, LdaTel: +351 21 312 20 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Servier Pharma, dooTel .: +385 (0) 1 3016 222<\/td><td><strong>Romania<\/strong>Servier Pharma SRLTel: +4 021 528 52 80<\/td><\/tr><tr><td><strong>Ireland<\/strong>Servier Laboratories (Ireland) Ltd.Tel: +353 (0) 1 663 8110<\/td><td><strong>Slovenia<\/strong>Servier Pharma dooTel: + 386 (0) 1 563 48 11<\/td><\/tr><tr><td><strong>Iceland<\/strong>Servier LaboratoriesC \/ o Icepharma hfPhone: +354 540 8000<\/td><td><strong>Slovak Republic<\/strong>Servier Slovensko spol.&nbsp;s roTel: +421 (0) 2 5920 41 11<\/td><\/tr><tr><td><strong>Italy<\/strong>Istituto Farmaco Biologico Stroder SrlTel: +39 06 669081<\/td><td><strong>Finland \/ Finland<\/strong>Servier Finland OyP.\/Tel: +358 (0) 9 279 80 80<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA Servier LatviaTel: + 371 6750 2039<\/td><td><strong>United Kingdom<\/strong>Servier Laboratories LtdTel: +44 (0) 1 753 666409<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Corlentor ( ivabradine ) is a heart medicine used to treat. <\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6607,6609,6610,6602,6604,6605,2212,6611,6606,2210,6608,6603],"class_list":["post-7057","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-corlentor","tag-corlentor-side-effects","tag-corlentor-tablet","tag-ivabradine","tag-ivabradine-side-effects","tag-ivabradine-tablet","tag-medicine","tag-side-effects-of-corlentor","tag-side-effects-of-ivabradine","tag-tablet","tag-what-is-corlentor","tag-what-is-ivabradine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7057","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7057"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7057\/revisions"}],"predecessor-version":[{"id":11268,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7057\/revisions\/11268"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7057"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7057"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7057"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}