{"id":7033,"date":"2021-02-10T13:32:05","date_gmt":"2021-02-10T13:32:05","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7033"},"modified":"2021-06-02T07:58:44","modified_gmt":"2021-06-02T07:58:44","slug":"conoxia","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/conoxia\/","title":{"rendered":"Conoxia &#8211; Oxygen uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n100%&nbsp;Medical gas, compressed&nbsp;<br>oxygen<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Conoxia is and what it is used for<\/h2>\n\n\n\n<p><strong>What Conoxia is<\/strong><\/p>\n\n\n\n<p>Conoxia contains oxygen that is used for inhalation.&nbsp;It is colorless, odorless, and tasteless and is supplied in a gas bottle that has a pressure regulator to reduce the gas pressure.&nbsp;The gas cylinder contains only pure oxygen.<br><\/p>\n\n\n\n<p>Conoxia increases the level of oxygen in the blood (increased oxygen saturation).&nbsp;Conoxia means that more oxygen is transported to all&nbsp;tissues in the&nbsp;body.<br><\/p>\n\n\n\n<p><strong>What Conoxia is used for<\/strong><\/p>\n\n\n\n<p>Under normal pressure, Conoxia is used:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>for the treatment of&nbsp;acute&nbsp;or&nbsp;chronic&nbsp;hypoxia&nbsp;(low levels of oxygen in the blood).<\/li><li>as part of the gas flow under general anesthesia, and intensive care.<\/li><li>to operate a&nbsp;nebulizer&nbsp;while inhaling inhaled drugs.<\/li><li>as first aid treatment with 100% oxygen in connection with diving accidents.<\/li><li>for the treatment of&nbsp;an acute&nbsp;attack of&nbsp;Horton&#8217;s headache.<br><\/li><\/ul>\n\n\n\n<p>Conoxia under normal pressure can be used in all age groups except in children who should not be treated with Conoxia in an&nbsp;acute&nbsp;attack of&nbsp;Horton&#8217;s headache.<br><\/p>\n\n\n\n<p>Under high pressure, Conoxia can be used in so-called pressure chambers to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increase the content of oxygen in the blood and other&nbsp;tissues&nbsp;to reduce the risk of injury caused by:<ul><li>diving sickness, gas or air bubbles in blood vessels.<\/li><\/ul><\/li><li>Treat carbon monoxide poisoning<\/li><li>Treat&nbsp;infection&nbsp;in&nbsp;tissues&nbsp;(&nbsp;clostridium&nbsp;myonecrosis,&nbsp;gas gangrene&nbsp;)<\/li><\/ul>\n\n\n\n<p>Conoxia in pressure chambers can be used in all age groups (see also section 2).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Conoxia&nbsp;<\/h2>\n\n\n\n<p>Inform your doctor so that he\/she is aware of any medical conditions you have or may have before using Conoxia.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Conoxia should not be used in pressure chambers if you have:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>an untreated injury to the alveoli, so-called pneumothorax.<\/li><li>have undergone&nbsp;surgery&nbsp;or have injuries to the body, as these events can form gas bubbles in the body.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Talk to a doctor if you suffer from&nbsp;chronic&nbsp;lung diseases such as&nbsp;asthma&nbsp;or&nbsp;chronic obstructive pulmonary disease&nbsp;(COPD).<\/li><li>Newborns, especially premature babies, are more sensitive to oxygen than adults.&nbsp;Only supply the amount of oxygen that you have been instructed by your healthcare professional.<\/li><li>If you have been prescribed treatment in a pressure chamber (hyperbaric oxygen therapy), the risk associated with damage to the alveoli (so-called pneumothorax) must be considered.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Conoxia should not be used to treat an&nbsp;acute&nbsp;attack of&nbsp;Horton&#8217;s headache&nbsp;in children and adolescents.<\/p>\n\n\n\n<p>Experience with Conoxia under high pressure in newborns, children, and adolescents is limited.<\/p>\n\n\n\n<p>The benefit\/risk balance should be evaluated for each patient.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Conoxia<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>If you use or have been prescribed:<\/p>\n\n\n\n<p>bleomycin, cisplatin or doxorubicin (a medicine used to treat cancer),&nbsp;amiodarone(a medicine used to treat heart disease), quarantine (&nbsp;nitrofurantoin&nbsp;) or similar&nbsp;antibiotics&nbsp;(a medicine used to treat&nbsp;infection&nbsp;),&nbsp;disulfiram&nbsp;(a medicine used to treat alcohol abuse), and chemicals such as paraquat, Inform your doctor before taking these medicines, as there is a risk that the treatment may increase the risk of lung damage.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><em>Conoxia under normal pressure<\/em><\/p>\n\n\n\n<p>Conoxia can be used during pregnancy and breast-feeding.&nbsp;Treatment with Conoxia has no known adverse effects on&nbsp;fertility.<br><\/p>\n\n\n\n<p><em>Conoxia under high pressure<\/em><\/p>\n\n\n\n<p>If you have been prescribed Conoxia in a pressure chamber, tell your doctor if you are pregnant or think you may be pregnant, as there is a possible risk of harm to the fetus caused by oxygen stress.<\/p>\n\n\n\n<p>There are no known&nbsp;side effects&nbsp;during breast-feeding as Conoxia is used in pressure chambers.&nbsp;However, breastfeeding should be avoided during the treatment itself as there is a risk that the newborn baby will be exposed to the pressure and compression in the pressure chamber.&nbsp;It is safe to breastfeed before and after treatment in a pressure chamber.<\/p>\n\n\n\n<p>The effect on&nbsp;fertility&nbsp;when Conoxia is used in pressure chambers has not been studied.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You can drive after using Conoxia provided your doctor thinks you are capable of it.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Conoxia<\/h2>\n\n\n\n<p>Always use this medicine exactly as described in this leaflet or as your doctor advised.&nbsp;Consult a doctor if you are unsure.&nbsp;Do not change the&nbsp;dose&nbsp;without first consulting a doctor.&nbsp;If you use this medicine at home, you will receive instructions at the first delivery, on how to use Conoxia and the equipment.<\/p>\n\n\n\n<p>Conoxia is used for&nbsp;inhalation.&nbsp;You usually breathe through a nasal mask or mask.&nbsp;Either you breathe yourself &#8211; you &#8220;spontaneously breathe&#8221; or you get help to breathe from a respirator\/ventilator.<\/p>\n\n\n\n<p><em>Carefully read the instructions for use \/ patient instructions for current breathing equipment!<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is determined individually for you, based on your medical condition.<\/li><\/ul>\n\n\n\n<p>The usual&nbsp;dose&nbsp;for adults to treat or prevent&nbsp;<em>acute&nbsp;hypoxia under normal pressure<\/em>&nbsp;is 2-6 liters per minute when using a nasal mask, or 5-10 liters per minute with a face mask and 10-15 liters per minute with a reservoir mask.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>For&nbsp;dosing&nbsp;in other cases consult a doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use in children and adolescents<\/h2>\n\n\n\n<p><em>Conoxia under normal pressure<\/em><\/p>\n\n\n\n<p>Children of all ages can be treated with Conoxia, but special consideration must be given to newborns.&nbsp;See also section 2.<br><\/p>\n\n\n\n<p><em>Conoxia under high pressure<\/em><\/p>\n\n\n\n<p>Children of all ages can be treated with Conoxia in a pressure chamber.&nbsp;The duration of treatment and how often your child should take Conoxia is determined by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Conoxia than you should<\/h2>\n\n\n\n<p>You may experience symptoms of overdose if you use more Conoxia than you were prescribed.&nbsp;Too much of this medicine can:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cause pain, dry cough, and shortness of breath<\/li><li>affect lung function and in rare cases (eg in some patients suffering from&nbsp;chronic lung disease) cause&nbsp;respiratory depression&nbsp;and unconsciousness.<br><\/li><\/ul>\n\n\n\n<p>If you notice these signs of Conoxia overdose, always consult a doctor.&nbsp;If you experience severe symptoms, consult a doctor or hospital immediately.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Safety instructions<\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>Smoking and open flames must not occur in rooms where Conoxia is used, as this increases the risk of fire.<\/li><li>Conoxia is for medical use only.<\/li><li>Only connect the bottle to the connection intended for medical oxygen.<\/li><li>The oxygen (containers and bottles) should only be used in areas with good ventilation.<\/li><li>The pressure regulator should be opened slowly and carefully to avoid ignition.<\/li><li>Never use grease, oil, or the like to lubricate threaded threads as there is a risk of self-ignition in contact with Conoxia under&nbsp;high pressure.<\/li><li>Handle valves and equipment with clean and grease-free hands (ie no use of hand cream, etc.).<\/li><li>Do not use a toaster, hairdryer, or similar electrical appliances during treatment with Conoxia.<\/li><li>Never apply an oxygen mask or nasal mask directly to textiles during treatment &#8211; textiles that have become oxygen-saturated can become very flammable\/flammable.&nbsp;If this should nevertheless occur, shake and ventilate such textiles properly.<\/li><li>In case of fire &#8211; switch off the equipment.<\/li><li>Gas cylinders must be carried safely in the event of a fire hazard.<\/li><li>Switch off the equipment when not in use.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Conoxia can cause&nbsp;side effects,&nbsp;although not everybody gets them.&nbsp;Side effects&nbsp;are usually seen at high concentrations (above 70%) and after prolonged treatment (at least 6 &#8211; 12 hours).<br><\/p>\n\n\n\n<p><em>Conoxia treatment under normal pressure<\/em><\/p>\n\n\n\n<p>The most serious&nbsp;side effect&nbsp;that can occur is difficulty breathing, so-called&nbsp;acute pulmonary failure \/ respiratory distress syndrome (which can lead to&nbsp;pulmonary fibrosis&nbsp;).&nbsp;If you have difficulty breathing, stop taking the medicine and seek medical attention immediately.<br><\/p>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<p>Dry mucous membranes in the nose and mouth due to the gas being dry.&nbsp;Pain when breathing, dry cough, and shortness of breath.<br><\/p>\n\n\n\n<p><em>Rare<\/em>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<p>In newborns exposed to high oxygen concentrations: Damage to the eye which may lead to impaired vision.<\/p>\n\n\n\n<p>Respiratory depression<br><\/p>\n\n\n\n<p><em>Very rare<\/em>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<p>Difficulty breathing&nbsp;Acute&nbsp;pulmonary failure \/ respiratory distress syndrome.&nbsp;Burn<\/p>\n\n\n\n<p>If you get any of these&nbsp;side effects, stop taking the treatment and consult a doctor.<br><\/p>\n\n\n\n<p><em>Conoxia treatment under high pressure<\/em><\/p>\n\n\n\n<p>The most serious&nbsp;side effects&nbsp;are confusion and seizures (&nbsp;epilepsy&nbsp;).&nbsp;Medical personnel is always present when you are being treated with Conoxia under high pressure.&nbsp;Your doctor will take action if you notice any of these&nbsp;side effects.<br><\/p>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<p>Feeling of pressure in the middle ear, cracked eardrum<br><\/p>\n\n\n\n<p><em>Rare<\/em>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<p>Feeling of pressure or pain in the nose<br><\/p>\n\n\n\n<p><em>Very rare<\/em>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<p>Anxiety, impaired vision, barotrauma (tissue damage due to the pressure effect), confusion, unconsciousness, and seizures (&nbsp;epilepsy&nbsp;).<br><\/p>\n\n\n\n<p><strong>Additional&nbsp;side effects&nbsp;are in children<\/strong><\/p>\n\n\n\n<p><em>Conoxia treatment under normal pressure<\/em><\/p>\n\n\n\n<p>Special consideration must be given when treating newborns as they are more sensitive to certain&nbsp;side effects&nbsp;than other patient groups.<\/p>\n\n\n\n<p>The most serious&nbsp;adverse reactions&nbsp;were of the newborn is damage to the eye (retrolental&nbsp;fibroplasia&nbsp;) that can cause vision loss and lung damage (called bronchial&nbsp;pulmonary&nbsp;dysplasia).<\/p>\n\n\n\n<p>If you suspect that your child has any of these&nbsp;side effects, stop the treatment and contact your doctor immediately.<\/p>\n\n\n\n<p>Apart from these serious&nbsp;side effects&nbsp;just described, there are no other known&nbsp;side effects&nbsp;in children other than those reported in adults.<br><\/p>\n\n\n\n<p><em>Conoxia treatment under high pressure<\/em><\/p>\n\n\n\n<p>There are no other known&nbsp;side effects&nbsp;caused by Conoxia in pressure chambers than those reported in adults.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Conoxia<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Store the bottle in a well-ventilated place where it is not exposed to strong heat.<\/li><li>Keep the bottle clean and dry.<\/li><li>Make sure that the gas cylinders are not exposed to shocks and falls.<\/li><li>Store away from flammable substances.<\/li><li>Do not use this medicine after the expiry date which is stated on the label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Do not use this medicine if the gas bottle does not have an intact seal when it is delivered to you.<\/li><li>Must be stored and transported with the valve closed and the protective plug and cover fitted where such occurs.<\/li><li>The bottle must be returned to the supplier.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is 100% oxygen.&nbsp;(Chemical name: O&nbsp;<sub>2<\/sub>&nbsp;).<\/li><li>No other ingredients are included in Conoxia.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The shoulder of the gas cylinder is marked with white color for oxygen.&nbsp;The body of the gas bottle is white (medical gas).<\/p>\n\n\n\n<p>Bottles\/packages filled to 200 bar, 153 bar * and 138 bar **, respectively, contain about X liters of gas at atmospheric pressure and 15 \u00b0 C according to the table below: Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Bottle size in liters<\/td><td>1<\/td><td>1.1<\/td><td>1.2<\/td><td>2<\/td><td>2.5<\/td><td>3<\/td><td>4<\/td><td>4.7<\/td><td>5<\/td><\/tr><tr><td>Liter gas<\/td><td>210<\/td><td>230<\/td><td>260<\/td><td>430<\/td><td>530<\/td><td>630<\/td><td>850<\/td><td>1000<\/td><td>1060<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Bottle size in liters<\/td><td>6<\/td><td>10<\/td><td>15<\/td><td>20<\/td><td>21.3 *<\/td><td>21.3 **<\/td><td>50<\/td><\/tr><tr><td>Liter gas<\/td><td>1260<\/td><td>2120<\/td><td>3180<\/td><td>4200<\/td><td>3450<\/td><td>2900<\/td><td>10 600<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Package size in liters<\/td><td>2 x 21.3 *<\/td><td>10&#215;50<\/td><td>12&#215;50<\/td><\/tr><tr><td>Liter gas<\/td><td>6900<\/td><td>106 000<\/td><td>128 000<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Manufacturer<\/h2>\n\n\n\n<p>Show larger<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong> Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Denmark<\/td><td>Conoxia<\/td><\/tr><tr><td>Estonia<\/td><td>CONOXIA<\/td><\/tr><tr><td>Finland<\/td><td>CONOXIA<\/td><\/tr><tr><td>Iceland<\/td><td>CONOXIA<\/td><\/tr><tr><td>Latvia<\/td><td>CONOXIA&nbsp;<\/td><\/tr><tr><td>Lithuania<\/td><td>CONOXIA&nbsp;<\/td><\/tr><tr><td>Norway<\/td><td>Conoxia<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Conoxia contains oxygen that is used for inhalation. It is colorless, odorless, and tasteless and is supplied in a gas bottle that has a pressure regulator to reduce the gas pressure. The gas cylinder contains only pure oxygen.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6652,6659,6660,6655,6654,6658,6656,6657,6653],"class_list":["post-7033","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-conoxia","tag-conoxia-dsoe","tag-conoxia-gas","tag-conoxia-medical-gas","tag-conoxia-side-effects","tag-conoxia-uses","tag-medical-gas","tag-oxgen","tag-what-is-conoxia"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7033"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7033\/revisions"}],"predecessor-version":[{"id":11280,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7033\/revisions\/11280"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}