{"id":6969,"date":"2021-02-06T16:07:01","date_gmt":"2021-02-06T16:07:01","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6969"},"modified":"2021-06-02T10:18:16","modified_gmt":"2021-06-02T10:18:16","slug":"colobreathe","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/colobreathe\/","title":{"rendered":"Colobreathe &#8211; Colistimethate Sodium uses, dose and side effects"},"content":{"rendered":"\n<p> 1,662,500 IU&nbsp;inhalation powder, hard capsules&nbsp;<br>colistimethate sodium<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Colobreathe is and what it is used for<\/h2>\n\n\n\n<p>Colobreathe contains colistimethate sodium, a type of&nbsp;antibiotic&nbsp;called polymyxin.<br><\/p>\n\n\n\n<p>Colobreathe is used to control persistent lung infections caused by the bacterium&nbsp;<em>Pseudomonas aeruginosa&nbsp;in adult patients and children over 6 years of age with&nbsp;cystic fibrosis<\/em>.&nbsp;<em>Pseudomonas aeruginosa<\/em>&nbsp;is a very common&nbsp;bacterium&nbsp;that infects almost all patients with&nbsp;cystic fibrosis&nbsp;at some point in their lives.&nbsp;Some people get this&nbsp;infection&nbsp;when they are very young, but others get it much later.&nbsp;If this&nbsp;infection is&nbsp;not managed properly, the lungs will be damaged.<br><\/p>\n\n\n\n<p>This is how it works:<\/p>\n\n\n\n<p>Colobreathe works by destroying the bacteria&#8217;s&nbsp;cell membranes.&nbsp;It has a deadly effect on them.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Colobreathe<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Colobreathe<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you \/ your child are allergic to colistimethate sodium, colistin sulfate, or polymyxins<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Colobreathe.<br><\/p>\n\n\n\n<p><strong>Tell your doctor if any of the following have ever affected you \/ your child<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have reacted negatively to drugs with dry powder for&nbsp;inhalation, unless this has already been discussed with your doctor<\/li><li>already have a muscle&nbsp;condition&nbsp;called&nbsp;myasthenia gravis&nbsp;or the inherited condition&nbsp;porphyria<\/li><li>blood in accumulated mucus.<\/li><\/ul>\n\n\n\n<p>After each&nbsp;inhalation&nbsp;of Colobreathe, rinse your mouth with water.&nbsp;Do not swallow the water.&nbsp;Rinsing can reduce the risk of developing superinfection of fungus in the oral cavity during treatment, and may also reduce the unpleasant taste associated with colistimethate sodium.<br><\/p>\n\n\n\n<p>When you \/ your child starts using Colobreathe, you \/ your child may notice that you may cough, become short of breath, have a feeling of tightness in the chest, or get a wheezing breathing sound.&nbsp;The number of these&nbsp;side effects&nbsp;may decrease as you continue to use the inhaler or your doctor may&nbsp;prescribe&nbsp;a tracheal dilator that you should take before taking Colobreathe.&nbsp;Contact your doctor if any of these effects become problematic so that he\/she can change the treatment.&nbsp;If you \/ your child have any problems with the kidneys or nerves, you must be careful when using Colobreathe but your doctor should be aware of this.<br><\/p>\n\n\n\n<p>If you \/ your child needs to take other forms of colistimethate, either as an&nbsp;injection&nbsp;or in a&nbsp;nebulizer, caution should be&nbsp;exercised but your&nbsp;doctor should be aware of this.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Do not give Colobreathe to children under 6 years of age as it is not suitable for them.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Colobreathe<\/h2>\n\n\n\n<p>Tell your doctor if you \/ your child are taking, have recently taken, or might take other medicines, and especially:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you \/ your child are taking aminoglycoside antibiotics used to treat&nbsp;the infection&nbsp;you need to be careful<\/li><li>if you \/ your child has&nbsp;myasthenia gravis&nbsp;and is taking&nbsp;antibiotics&nbsp;type&nbsp;macrolide you such as azithromycin and clarithromycin, or&nbsp;fluoroquinolones&nbsp;you such as norfloxacin and&nbsp;ciprofloxacin.&nbsp;Using these at the same time as Colobreathe can cause muscle weakness<\/li><li>if you \/ your child is taking colistimethate as an&nbsp;injection&nbsp;or via a&nbsp;nebulizer, caution should be exercised<\/li><li>if you \/ your child needs anesthesia, caution must be exercised.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>There is no information on the safety of Colobreathe in pregnant women.&nbsp;Your doctor should talk to you about whether the benefits of this medicine outweigh the risks before using Colobreathe.<br><\/p>\n\n\n\n<p>Colistimethate sodium can be excreted in human milk.&nbsp;Discuss the use of Colobreathe with your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p class=\"has-drop-cap\">It is possible that when you use Colobreathe, you may experience dizziness, confusion, or vision problems.&nbsp;Do not drive or use any machinery until symptoms have resolved.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Colobreathe contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per capsule, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Colobreathe<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Consult your doctor if you \/ your child is unsafe\/unsafe.<br><\/p>\n\n\n\n<p>The first&nbsp;dose&nbsp;should be given under medical supervision.<br><\/p>\n\n\n\n<p><strong><em>The recommended&nbsp;dose&nbsp;is<\/em><\/strong><br><\/p>\n\n\n\n<p><strong>Adults and children over 6 years<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The contents of a Colobreathe capsule should be inhaled twice daily using the Turbospin inhaler.<\/li><li>There should be 12 hours between each&nbsp;dose.<\/li><\/ul>\n\n\n\n<p><strong>The order in which other treatments are to be taken or performed<\/strong><br><\/p>\n\n\n\n<p>If you \/ your child receives other treatment for&nbsp;cystic fibrosis, they should be taken in this order:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inhaled tracheal dilators<\/li><li>Breathing gymnastics<\/li><li>Other inhaled drugs<\/li><li>Sedan Colobreathe<\/li><\/ul>\n\n\n\n<p>You \/ your child should go through the order of your treatments with the doctor.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/Turbospin20inhaler20A.jpg\" alt=\"Turbospin inhaler\"\/><\/a><\/figure>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Colobreathe is inhaled into the lungs as a powder from the capsule using the inhaler called Turbospin.&nbsp;Colobreathe can only be taken with the help of Turbospin.<br><\/p>\n\n\n\n<p><strong>Do not swallow the Colobreathe capsules.<\/strong><br><\/p>\n\n\n\n<p>Inhale Colobreathe from the capsule through the Turbospin inhaler according to the procedure described below.&nbsp;Your doctor or nurse will show you \/ your child how to inhale the medicine when you \/ your child starts treatment:<br><\/p>\n\n\n\n<p><strong>How to take Colobreathe using the Turbospin inhaler<\/strong><br><\/p>\n\n\n\n<p><strong>Preparation of Turbospin<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20120150209.jpg\" alt=\"Picture 1\"\/><\/a><\/figure>\n\n\n\n<p>1. Remove the cover.&nbsp;It comes loose if you pull carefully.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20220150209.jpg\" alt=\"Picture 2\"\/><\/a><\/figure>\n\n\n\n<p>2. Unscrew the nozzle so that the chamber of the Turbospin inhaler is exposed.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20320150209.jpg\" alt=\"Picture 3\"\/><\/a><\/figure>\n\n\n\n<p>3. Remove a single capsule from the blister pack.&nbsp;After removing the capsule, it must be used immediately.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20420150209.jpg\" alt=\"Picture 4\"\/><\/a><\/figure>\n\n\n\n<p>4. Carefully insert the capsule into the chamber with the widest end first.&nbsp;No power needed.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20520150209.jpg\" alt=\"Picture 5\"\/><\/a><\/figure>\n\n\n\n<p>5. Now replace the nozzle by screwing it in place.<br><\/p>\n\n\n\n<p><strong>How to pierce the capsule and inhale the medicine<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20620150209.jpg\" alt=\"Figure 6\"\/><\/a><\/figure>\n\n\n\n<p>6. To pierce the capsule:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hold the inhaler with the mouthpiece straight up, gently push the plunger upwards until the visible line is reached &#8211; you will feel resistance here and this locks the capsule ready to be pierced.&nbsp;Hold that position before continuing with the piercing.<\/li><li>Now that the capsule is locked, continue to push the plunger as far as it will go and then release it.<\/li><li>The capsule is now pierced and the contents can be inhaled.<\/li><li>Pierce&nbsp;<strong>is not<\/strong>&nbsp;the capsule more than once.&nbsp;You can see a small amount of powder being released from the chamber after the capsule has been pierced.&nbsp;This is normal.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20100625000011#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Forest20Laboratories\/Media\/Colobreathe\/bild20720150209.jpg\" alt=\"Picture 7\"\/><\/a><\/figure>\n\n\n\n<p>7. Exhale slowly.&nbsp;Place the nozzle between your lips and teeth.&nbsp;Make sure it is tight between the lips and the nozzle.&nbsp;Be careful not to cover the air gaps with your fingers or mouth during&nbsp;inhalation.<br><\/p>\n\n\n\n<p>8. Then inhale slowly and deeply through your mouth at a rate sufficient for you to hear or feel the capsule spin.<br><\/p>\n\n\n\n<p>9. Remove the Turbospin inhaler from your mouth and hold your breath for about 10 seconds, or as long as it feels comfortable, then exhale slowly.<br><\/p>\n\n\n\n<p>10. If you do not hear the capsule spin, the capsule may be stuck in the compartment.&nbsp;If this happens, you can release the capsule by gently tapping the inhaler chamber.&nbsp;Do not attempt to release the capsule by repeatedly pressing the plunger.&nbsp;If the capsule cannot be released and the powder cannot be inhaled, discard the broken capsule and any powder left in it and use another.<br><\/p>\n\n\n\n<p>11. Inhale the medicine again by repeating steps 7 and 8 to make sure you have emptied the capsule.<br><\/p>\n\n\n\n<p>12. You can check if the capsule is empty by unscrewing the nozzle and checking the capsule.&nbsp;If it is not empty, repeat steps 7, 8, and 9 until you have inhaled all the contents.<br><\/p>\n\n\n\n<p>13. When all contents have been inhaled, rinse the mouth thoroughly with water and spit out.<br><\/p>\n\n\n\n<p><strong>How to remove the empty capsule from Turbospin<\/strong><\/p>\n\n\n\n<p>14. When the capsule is empty, unscrew the nozzle, remove and discard the empty capsule.<br><\/p>\n\n\n\n<p><strong>More information<\/strong><br><\/p>\n\n\n\n<p>When you inhale slowly, suck in air through the Turbospin inhaler and into the capsule chamber.&nbsp;The small drug particles in the capsule are captured by the airflow and transported through the airways down to the lungs.<br><\/p>\n\n\n\n<p>Sometimes very small parts of the capsule cover can enter the mouth or respiratory tract.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If this happens, you may feel these bits on your tongue or in your airways.<\/li><li>The capsule cover is made of gelatin, which is harmless to humans if swallowed or inhaled.<\/li><li>The risk of the canister breaking into pieces increases if the canister is pierced more than once in step 6.<\/li><\/ul>\n\n\n\n<p><strong>Cleaning the Turbospin unit<\/strong><\/p>\n\n\n\n<p>Clean the Turbospin inhaler after each&nbsp;dose&nbsp;according to the following procedure:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Press the plunger deep a few times while holding the chamber up and down.<\/li><li>Clean the chamber with a cloth or cotton swab.&nbsp;Do not use water.<\/li><li>Screw on the mouthpiece firmly and replace the cap, then the inhaler is ready to use for your next&nbsp;dose.<\/li><\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">If you \/ your child have taken too much Colobreathe, or inadvertently swallowed one capsule,<\/h2>\n\n\n\n<p>you should contact your doctor immediately for advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you \/ your child have forgotten to use Colobreathe<\/h2>\n\n\n\n<p>If you \/ your child forgets to take a&nbsp;dose&nbsp;of Colobreathe, you \/ your child should take the missed&nbsp;dose&nbsp;as soon as you \/ your child remembers.&nbsp;You \/ your child must not take 2&nbsp;doses&nbsp;at intervals of less than 12 hours.&nbsp;Continue from there according to the instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you \/ your child stop using Colobreathe<\/h2>\n\n\n\n<p>Do not stop treatment prematurely unless your doctor tells you to.&nbsp;Your doctor decides how long your \/ your child&#8217;s treatment should last.<br><\/p>\n\n\n\n<p>If you \/ your child have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Allergic reactions<\/strong><\/p>\n\n\n\n<p>An&nbsp;allergic reaction&nbsp;caused by Colobreathe is possible (usually severe allergic reactions can cause a rash, swelling of the face, tongue, and throat, inability to breathe due to narrowing of the airways, and unconsciousness).&nbsp;If you \/ your child experience signs of an&nbsp;allergic reaction<strong>, you should seek medical attention immediately.<\/strong><br><\/p>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<p>You \/ your child may get an unpleasant taste in the mouth after&nbsp;inhaling&nbsp;Colobreathe.<br><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(affects more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty breathing<\/li><li>Cough, throat irritation<\/li><li>Hoarseness or weak voice, or even losing your voice<\/li><li>Unpleasant taste<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(affects up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Ringing or buzzing sound in the ear, balance disorder<\/li><li>Coughing up of blood, wheezing breathing, chest discomfort,&nbsp;asthma, productive cough (when coughing up mucus),&nbsp;infection&nbsp;in the lungs, crackling sound in the lungs (your doctor hears this when he\/she listens to the lungs with a stethoscope)<\/li><li>Vomiting, nausea<\/li><li>Changes in lung function (detected by testing)<\/li><li>Joint pain<\/li><li>Lack of energy, fatigue<\/li><li>Elevated temperature<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(affects up to 1 in 100 people):<\/p>\n\n\n\n<p>Allergic reactions (&nbsp;hypersensitivity reactions&nbsp;), symptoms may include rash and&nbsp;itching<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Weight changes decreased appetite<\/li><li>Anxiety<\/li><li>Seizures<\/li><li>Somnolence<\/li><li>Blockage in the ears<\/li><li>Chest pain<\/li><li>Shortness of breath<\/li><li>Nasal blood, catarrh (mucus in the nose that can make you feel stuffy), thick cough, green mucus, pain in the throat and sinuses<\/li><li>Unusual sounds in the chest (your doctor hears this when he\/she listens to your lungs with a stethoscope)<\/li><li>Diarrhea, gas<\/li><li>Heavy saliva production<\/li><li>Toothache<\/li><li>Protein&nbsp;in the urine (detected by testing)<\/li><li>Thirst<\/li><\/ul>\n\n\n\n<p>The above-mentioned&nbsp;side effects&nbsp;have occurred about as often in people of all ages.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Colobreathe<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the outer carton and on the blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store Colobreathe at a maximum of 25 \u00b0 C.<\/p>\n\n\n\n<p>Store in the original package until just before use.&nbsp;Moisture sensitive.<br><\/p>\n\n\n\n<p>If you \/ your child accidentally pull back the foil and some capsules appear, these capsules should be discarded.<br><\/p>\n\n\n\n<p>Discard the Turbospin inhaler after running out of the capsules in the package.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is colistimethate sodium (also called colistin).&nbsp;Each capsule contains 1,662,500 IU (equivalent to approximately 125 mg) colistimethate sodium.<br><\/p>\n\n\n\n<p>Other ingredients are:<br><\/p>\n\n\n\n<p><strong>Capsule cover<\/strong><\/p>\n\n\n\n<p>Gelatine<\/p>\n\n\n\n<p>Polyethylene glycol<\/p>\n\n\n\n<p>Sodium lauryl sulfate<\/p>\n\n\n\n<p>Purified water<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Colobreathe&nbsp;inhalation powder, hard capsule (&nbsp;inhalation powder&nbsp;), is supplied as small, hard, transparent gelatin capsules containing a fine, white powder.<br><\/p>\n\n\n\n<p>Turbo spin is a dry powder inhaler that is driven by&nbsp;inspiratory flow, and which is made of polypropylene and stainless steel.<br><\/p>\n\n\n\n<p>The capsules are delivered in blister packs, and each packing box contains:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>56 hard capsules &#8211; a Turbospin dry powder inhaler that lasts for 4 weeks.<\/li><li>8 hard capsules &#8211; a Turbospin dry powder inhaler that lasts for 4 days.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n<p>Teva BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>2031 GA Haarlem<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>Penn Pharmaceutical Services Limited<\/p>\n\n\n\n<p>Tafarnaubach Industrial Estate<\/p>\n\n\n\n<p>Tredegar<\/p>\n\n\n\n<p>Gwent<\/p>\n\n\n\n<p>NP22 3AA<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>Teva Pharmaceuticals Europe BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>2031 GA Haarlem<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p>Millmount Healthcare Limited<\/p>\n\n\n\n<p>Block 7, City North Business Campus<\/p>\n\n\n\n<p>Stamullen<\/p>\n\n\n\n<p>Co Meath<\/p>\n\n\n\n<p>Ireland<br><\/p>\n\n\n\n<p>Merckle GmbH<\/p>\n\n\n\n<p>Ludwig-Merckle-Str-3<\/p>\n\n\n\n<p>89143 Blaubeuren<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine: Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Teva Pharma Belgium NV \/ SA \/ AGTel: +32 3 820 73 73<\/td><td><strong>Lithuania<\/strong>UAB \u201cSicor Biotech\u201dTel: +370 5 266 02 03<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Octavis FADTel: +359 24899585<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>Teva Pharma Belgium NV \/ SA \/ AGBelgium \/ BelgiumTel: +32 38207373<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Teva Pharmaceuticals CR, sroTel: +420 251007111<\/td><td><strong>Hungary<\/strong>Teva Gy\u00f3gyszergy\u00e1r Zrt.Tel: +36 12886400<\/td><\/tr><tr><td><strong>Denmark<\/strong>Teva Denmark A \/ STel: +45 44985511<\/td><td><strong>Malta<\/strong>Actavis Ltd.Tel: +356 21693533<\/td><\/tr><tr><td><strong>Germany<\/strong>TEVA GmbHTel: +49 73140208<\/td><td><strong>The Netherlands<\/strong>Teva Nederland BVTel: +31 8000228400<\/td><\/tr><tr><td><strong>Eesti<\/strong>UAB &#8220;Sicor Biotech&#8221; Eesti subsidiaryTel: +372 6610801<\/td><td><strong>Norway<\/strong>Teva Norway ASTel: +47 66775590<\/td><\/tr><tr><td><strong>Greece<\/strong>Specify ABEE:\u0397\u03bb: +30 2118805000<\/td><td><strong>Austria<\/strong>ratiopharm Arzneimittel Vertriebs-GmbHTel: +43 1970070<\/td><\/tr><tr><td><strong>Spain<\/strong>Teva Pharma, SLUTel: +34 913873280<\/td><td><strong>Poland<\/strong>Teva Pharmaceuticals Polska Sp.&nbsp;z ooTel: +48 223459300<\/td><\/tr><tr><td><strong>France<\/strong>Teva HealthTel: +33155917800<\/td><td><strong>Portugal<\/strong>Teva Pharma &#8211; Pharmaceutical Products, Lda.Tel: +351 214767550<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pliva Hrvatska dooTel: + 385 13720000<\/td><td><strong>Romania<\/strong>Teva Pharmaceuticals SRLTel: +40 212306524<\/td><\/tr><tr><td><strong>Ireland<\/strong>Teva Pharmaceuticals IrelandTel: +353 19127700<\/td><td><strong>Slovenia<\/strong>Pliva Ljubljana dooTel: +386 15890390<\/td><\/tr><tr><td><strong>Iceland<\/strong>Actavis Group PTC ehf.Phone: +354 5503300<\/td><td><strong>Slovak Republic<\/strong>TEVA Pharmaceuticals Slovakia sroTel: +421 257267911<\/td><\/tr><tr><td><strong>Italy<\/strong>Teva Italia SrlTel:.&nbsp;+39 028917981<\/td><td><strong>Finland \/ Finland<\/strong>Teva Finland OyPuh \/ Tel: +358 201805900<\/td><\/tr><tr><td><strong>Latvia<\/strong>UAB &#8220;Sicor Biotech&#8221; branch of LatviaTel: +371 67323666<\/td><td><strong>United Kingdom<\/strong>Teva UK LimitedTel: +44 1977628500<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Colobreathe contains colistimethate sodium, a type of antibiotic called polymyxin.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6761,6764,6763,6766,6769,6768,6765,6770,6762,6767],"class_list":["post-6969","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-colistimethate-sodium","tag-colistimethate-sodium-capsule","tag-colistimethate-sodium-side-effects","tag-colobreathe","tag-colobreathe-capsule","tag-colobreathe-side-effects3","tag-side-effects-of-colistimethate-sodium","tag-side-effects-of-colobreathe","tag-what-is-colistimethate-sodium","tag-what-is-colobreathe"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6969","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6969"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6969\/revisions"}],"predecessor-version":[{"id":11306,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6969\/revisions\/11306"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6969"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6969"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6969"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}