{"id":6955,"date":"2021-02-06T11:27:17","date_gmt":"2021-02-06T11:27:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6955"},"modified":"2021-06-04T09:48:45","modified_gmt":"2021-06-04T09:48:45","slug":"colazid","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/colazid\/","title":{"rendered":"Colazide &#8211; Disodium Balsalazide uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n750 mg&nbsp;capsules&nbsp;<br>disodium balsalazide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Colazid is and what it is used for<\/h2>\n\n\n\n<p>Colazide is used to treat&nbsp;ulcerative colitis&nbsp;(&nbsp;inflammation&nbsp;and ulcers in the colon).&nbsp;It can also be used as a maintenance treatment to keep the disease under control and prevent a recurrence.&nbsp;It acts as an anti-inflammatory drug.<br><\/p>\n\n\n\n<p>This medicine contains disodium balsalazide as an active substance.<br><\/p>\n\n\n\n<p>Disodium balsalazide contained in Colazid may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Colazid<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Colazid:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to disodium balsalazide or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are allergic to mesalazine,&nbsp;acetylsalicylic acid,&nbsp;or other salicylates<\/li><li>if you have severe liver disease<\/li><li>if you have moderate or severe renal impairment<\/li><li>if you are pregnant or breastfeeding<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>asthma<\/li><li>any blood diseases<\/li><li>mild kidney disease<\/li><li>confirmed liver disease<\/li><li>active&nbsp;stomach ulcer<\/li><\/ul>\n\n\n\n<p>If any of these apply to you, talk to your doctor or pharmacist before taking Colazid.<br><\/p>\n\n\n\n<p><strong>Control of your liver, kidney, and blood<\/strong><\/p>\n\n\n\n<p>Before starting treatment with Colazid, you will be given a blood and urine test to check how well your kidneys and blood are working.<\/p>\n\n\n\n<p>During treatment, your doctor may take blood and urine samples to check that your liver, kidneys, and blood are functioning properly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Colazid is not recommended for use in children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Colazid<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This applies in particular to&nbsp;digoxin&nbsp;(used to treat heart problems), methotrexate (used to treat certain autoimmune diseases, such as&nbsp;rheumatoid arthritis,&nbsp;psoriasis, psoriatic arthritis,&nbsp;SLE, certain inflammatory bowel diseases (&nbsp;Crohn&#8217;s disease&nbsp;), and certain types of cancer, among other diseases), azathioprine (used to prevent rejection after organ transplantation and to treat&nbsp;rheumatoid arthritis, certain inflammatory bowel diseases (&nbsp;Crohn&#8217;s disease&nbsp;and&nbsp;ulcerative colitis) and&nbsp;multiple sclerosis among other diseases) and 6-mercaptopurine (used in the treatment of&nbsp;leukemia&nbsp;and inflammatory bowel diseases, such as&nbsp;Crohn&#8217;s disease and&nbsp;ulcerative colitis&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Colazide with food<\/h2>\n\n\n\n<p>Colazid should be taken with or after a meal.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>You should&nbsp;<strong>not<\/strong>&nbsp;take Colazid during pregnancy or breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>There is no evidence that Colazid would affect your ability to drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Colazid<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>Adult and elderly patients:<\/strong><\/p>\n\n\n\n<p><em>Treatment of ulcerative colitis:<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is 3 capsules 3 times a day with or after a meal.&nbsp;Swallow the capsules whole, with a glass of water if needed.<\/p>\n\n\n\n<p>The treatment can last for up to 12 weeks.<\/p>\n\n\n\n<p>Your doctor may also prescribe&nbsp;steroids&nbsp;to you while Colazide.<br><\/p>\n\n\n\n<p><em>Maintenance treatment to prevent relapse:<\/em><\/p>\n\n\n\n<p>The recommended starting dose is 2 capsules twice daily (3 g daily) with or after a meal.&nbsp;Swallow the capsules whole, with a glass of water if needed.&nbsp;Your doctor may change your&nbsp;dose&nbsp;depending on how you react to the medicine.<\/p>\n\n\n\n<p>There may be an additional benefit to a&nbsp;dose&nbsp;of up to 6 g daily.<br><\/p>\n\n\n\n<p>Drink enough fluids while taking this medicine to maintain your fluid level in the body, especially after severe or prolonged vomiting and\/or diarrhea, high fever, or heavy sweating.&nbsp;This is to avoid kidney problems.<br><\/p>\n\n\n\n<p>During treatment with Colazid, your doctor will take blood and urine samples.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Colazid is&nbsp;<strong>not<\/strong>&nbsp;recommended&nbsp;for use in children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Colazid<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose&nbsp;at the right time, take it as soon as possible after a meal.<\/p>\n\n\n\n<p>If you miss a&nbsp;dose&nbsp;completely, do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Take the next&nbsp;dose&nbsp;as usual.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you get:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>a severe&nbsp;allergic reaction&nbsp;may occur as swelling of the face and swelling of the tongue, lips, and throat,<\/strong><\/li><li><strong>abnormal bleeding, bruising, rash, fever, sore throat, or getting very tired.<\/strong><\/li><\/ul>\n\n\n\n<p>A blood test will be taken to check the blood count and treatment will be stopped immediately if there is a suspicion of blood disease.<br><\/p>\n\n\n\n<p><strong>Other&nbsp;<\/strong>side effects&nbsp;that can occur with Colazid are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash,<\/li><li>diarrhea, stomach pain, nausea, vomiting, headache,<\/li><li>gallstones, deterioration of&nbsp;ulcerative colitis,<\/li><li>effect on blood count,<\/li><li>difficulty breathing, cough, fever,<\/li><li>abnormal feeling or function (eg weakness or numbness), joint pain, muscle aches,<\/li><li>hair loss,<\/li><li>hypersensitivity.<\/li><\/ul>\n\n\n\n<p><strong>Kidney problems<\/strong>&nbsp;including renal impairment have been reported.&nbsp;Symptoms can be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blood or other changes in your urine,<\/li><li>rash, fever,<\/li><li>low back or joint pain,<\/li><li>accumulation of fluid in the body,<\/li><li>reduced urine output.<\/li><\/ul>\n\n\n\n<p><strong>Inflammation&nbsp;of the heart, liver, and&nbsp;pancreas<\/strong>&nbsp;has been reported.&nbsp;Symptoms of these are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Inflammation&nbsp;of the heart:<\/strong>&nbsp;chest pain, palpitations, shortness of breath, and fatigue.<\/li><li>Inflammation&nbsp;of the liver:&nbsp;flu-like symptoms, jaundice (yellowing of the skin and whites of the eyes), and abdominal pain.<\/li><li>Inflammation&nbsp;of the pancreas:&nbsp;abdominal pain, nausea, and vomiting.<\/li><\/ul>\n\n\n\n<p><strong>The systemic lupus erythematosus (&nbsp;SLE&nbsp;) -like syndrome<\/strong>&nbsp;has been reported.&nbsp;The symptoms are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inflammation&nbsp;of the joints, connective tissue, tendons, and organs such as the heart, lungs, kidneys, and skin.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Colazid<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;or EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is balsalazide (as disodium balsalazide).<\/li><li>Each capsule contains 750 mg of balsalazide (as disodium balsalazide).<\/li><li>The other ingredients (excipients) are magnesium stearate, anhydrous&nbsp;colloidal silica, gelatin, shellac, the dyes titanium dioxide (E 171), and red, yellow, and black iron oxide (E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Colazid is a hard beige capsule.<br><\/p>\n\n\n\n<p>Colazid is supplied in jars with child-resistant screw caps containing 130 capsules.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Almirall, SA<\/p>\n\n\n\n<p>Ronda General Miter, 151<\/p>\n\n\n\n<p>08022 Barcelona<\/p>\n\n\n\n<p>Spain<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Catalent Germany Schorndorf GmbH<\/p>\n\n\n\n<p>Steinbeisstrasse 1 + 2<\/p>\n\n\n\n<p>D-73614 Schorndorf<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names: <\/strong>Show larger<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Denmark<\/td><td>Premed 750 mg capsules<\/td><\/tr><tr><td>UK<\/td><td>Colazide 750 Mg Capsules<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Colazide is used to treat ulcerative colitis ( inflammation and ulcers in the colon). It can also be used as a maintenance treatment to keep the disease under control and prevent a recurrence. It acts as an anti-inflammatory drug.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[2239,6831,6834,6833,6826,6829,6828,6835,6830,6832,6827],"class_list":["post-6955","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-capsule","tag-colazide","tag-colazide-capsule","tag-colazide-side-effects","tag-disodium-balsalazide","tag-disodium-balsalazide-capsule","tag-disodium-balsalazide-side-effects","tag-side-effects-of-colazide","tag-side-effects-of-disodium-balsalazide","tag-what-is-colazide","tag-what-is-disodium-balsalazide"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6955"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6955\/revisions"}],"predecessor-version":[{"id":11321,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6955\/revisions\/11321"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6955"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6955"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}