{"id":6901,"date":"2021-02-01T08:28:02","date_gmt":"2021-02-01T08:28:02","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6901"},"modified":"2021-06-04T11:10:23","modified_gmt":"2021-06-04T11:10:23","slug":"clopidogrel-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/clopidogrel-actavis\/","title":{"rendered":"Clopidogrel Actavis &#8211; Clopidogrel uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n5 mg&nbsp;film-coated tablets&nbsp;<br>clopidogrel<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Clopidogrel Actavis is and what it is used for<\/h2>\n\n\n\n<p>Clopidogrel Actavis contains clopidogrel and belongs to a group of medicines called platelet inhibitors.&nbsp;Platelets&nbsp;are very small cells in the blood, which form&nbsp;clots&nbsp;(&nbsp;clots&nbsp;) when the&nbsp;blood&nbsp;coagulates&nbsp;(blood clots).&nbsp;By preventing this&nbsp;clot&nbsp;formation, platelet inhibitors reduce the risk of blood clots forming (a process known as&nbsp;thrombosis&nbsp;or blood clot formation).<br><\/p>\n\n\n\n<p>Clopidogrel Actavis used by adults to prevent blood clots (&nbsp;thrombosis&nbsp;s) in hardened blood vessels (&nbsp;artery&nbsp;s), a process known as&nbsp;atherothrombosis, which can lead to atherothrombotic events (such as stroke (&nbsp;stroke&nbsp;), heart attack or death).<br><\/p>\n\n\n\n<p>You have been given Clopidogrel Actavis to prevent the formation of blood clots and to reduce the risk of these serious events due to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You suffer from atherosclerosis (also known as atherosclerosis), and<\/li><li>You have previously had a heart attack, stroke or suffer from something called&nbsp;peripheral&nbsp;arterial&nbsp;disease, or<\/li><li>You have had severe angina (&nbsp;unstable angina&nbsp;) or heart attack (heart attack).&nbsp;To treat this condition, your doctor may have placed a&nbsp;stent&nbsp;in the blocked or narrowed blood vessel to restore effective blood flow.&nbsp;You should also get&nbsp;acetylsalicylic acid&nbsp;(a substance found in many medicines used to relieve pain and lower fever and also to prevent the formation of blood clots) from your doctor.<\/li><li>You have an irregular heartbeat, something called&nbsp;atrial fibrillation,&nbsp;and you cannot take blood-thinning drugs orally (&nbsp;vitamin&nbsp;K&nbsp;antagonists&nbsp;) that prevent new blood clots from forming and prevent existing blood clots from growing.&nbsp;You should have learned that orally, blood thinners are more effective than&nbsp;acetylsalicylic acid&nbsp;or the combination of Clopidogrel Actavis and&nbsp;acetylsalicylic acid&nbsp;for this disease.&nbsp;Your doctor should have given you Clopidogrel Actavis and&nbsp;acetylsalicylic acid&nbsp;if you are unable to take blood-thinning medicines orally and you are not at risk of heavy bleeding<\/li><\/ul>\n\n\n\n<p>Clopidogrel contained in Clopidogrel Actavis may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Clopidogrel Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Clopidogrel Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to clopidogrel, soybean oil, peanut oil, or any of the other ingredients of this medicine (see section 6)<\/li><li>if you suffer from any disease that causes you to have active bleeding, such as&nbsp;stomach ulcers&nbsp;or bleeding in the brain<\/li><li>if you have severe liver disease<\/li><\/ul>\n\n\n\n<p>If you think any of these apply to you or if you are not sure, talk to your doctor before taking Clopidogrel Actavis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Clopidogrel Actavis:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are at risk of bleeding, eg:<ul><li>a disease that puts you at risk of internal bleeding (such as&nbsp;stomach ulcers&nbsp;)<\/li><li>a blood disease that puts you at risk of internal bleeding (in the body&#8217;s&nbsp;tissues, organs, or joints)<\/li><li>a recent serious injury<\/li><li>a recent surgery (including dental surgery)<\/li><li>a planned operation (including dental operations) within the next week<\/li><\/ul><\/li><li>if you have had a clot in an&nbsp;artery&nbsp;in your brain (ischemic&nbsp;stroke&nbsp;) in the last 7 days<\/li><li>if you suffer from kidney or liver disease<\/li><li>if you have had an&nbsp;allergy&nbsp;or reaction to other medicines to treat your illness<\/li><\/ul>\n\n\n\n<p>While taking Clopidogrel Actavis<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You should inform your doctor if surgery (including dental surgery) is planned.<\/li><li>You should also tell your doctor immediately if you develop a condition (also known as Thrombotic Thrombocytopenic Purpura or TTP) that includes fever and bruising under the skin that may appear as red pin-sized dots, with or without unexplained extreme fatigue, confusion, yellowing of the skin. or yellow eyes (jaundice) (see section 4).<\/li><li>If you cut yourself or injure yourself, it may take longer than usual for the bleeding to stop.&nbsp;This is because of the way your medicine works because it prevents blood clots from forming.&nbsp;For minor cuts and injuries, such as if you cut yourself when shaving, this is usually not a problem.&nbsp;However, if you are concerned about your bleeding, contact your doctor immediately (see section 4).<\/li><li>Your doctor may order blood samples.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children as it does not help.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Clopidogrel Actavis<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Some other medicines may affect the use of Clopidogrel Actavis or vice versa.<br><\/p>\n\n\n\n<p>It is especially important that you tell your doctor if you are taking<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines that may increase your bleeding risk such as:<ul><li>blood-thinning drugs taken orally, drugs used to reduce the formation of blood clots,<\/li><li>non-steroidal anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;), which are commonly used to treat painful and\/or inflammatory conditions in muscles and joints,<\/li><li>heparin&nbsp;or any other medicine injected to reduce the formation of blood clots,<\/li><li>ticlopidine, another antiplatelet agent,<\/li><li>selective serotonin reuptake inhibitors (including but not limited to fluoxetine or fluvoxamine), medicines commonly used to treat depression,<\/li><\/ul><\/li><li>omeprazole or esomeprazole, medicines used to treat stomach upset,<\/li><li>fluconazole&nbsp;or voriconazole, medicines used to treat fungal infections,<\/li><li>efavirenz or other antiretroviral medicines (used to treat&nbsp;HIV&nbsp;infections&nbsp;),<\/li><li>carbamazepine, a drug used to treat various forms of&nbsp;epilepsy,<\/li><li>moclobemide, medicines used to treat depression,<\/li><li>repaglinide, medicines used to treat&nbsp;diabetes,<\/li><li>paclitaxel, medicines used to treat cancer,<\/li><li>opioids: when you are being treated with clopidogrel, you should inform your doctor before receiving treatment with&nbsp;opioids&nbsp;(used to treat severe pain).<\/li><\/ul>\n\n\n\n<p>If you have had severe chest pain (&nbsp;unstable angina&nbsp;or heart attack), you can be prescribed Clopidogrel Actavis in combination with&nbsp;acetylsalicylic acid, a substance found in many medicines used to relieve pain and lower fever.&nbsp;Temporary use of&nbsp;acetylsalicylic acid&nbsp;(not more than 1000 mg for 24 hours) is not generally considered a problem, but long-term use under other conditions should be discussed with your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Clopidogrel Actavis with food and drink<\/h2>\n\n\n\n<p>Clopidogrel Actavis can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>This medicine should preferably not be used during pregnancy.<br><\/p>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.&nbsp;If you become pregnant while taking Clopidogrel Actavis, you should contact your doctor immediately as it is not recommended to take clopidogrel during pregnancy.<br><\/p>\n\n\n\n<p>This medicine should not be used during breast-feeding.<\/p>\n\n\n\n<p>If you are breast-feeding or planning to breast-feed, talk to your doctor before taking this medicine.<br><\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Clopidogrel Actavis is unlikely to affect your ability to drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Clopidogrel Actavis contains lactose and soybean oil<\/h2>\n\n\n\n<p>Clopidogrel Actavis contains&nbsp;lactose.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p>Clopidogrel Actavis contains soybean oil.&nbsp;Do not take this medicine if you are allergic to peanuts or soy<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Clopidogrel Actavis<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose, including for patients with a condition called&nbsp;atrial fibrillation&nbsp;(irregular heartbeat), is one 75 mg tablet of Clopidogrel Actavis per day taken orally, with or without food, and at the same time each day.<br><\/p>\n\n\n\n<p>If you have had severe chest pain (&nbsp;unstable angina&nbsp;or heart attack), your doctor may give you Clopidogrel Actavis 300 mg (4 tablets of 75 mg) to start treatment.&nbsp;After this, the recommended&nbsp;dose is&nbsp;one of 75 mg Clopidogrel Actavis per day as described above.<br><\/p>\n\n\n\n<p>You should take Clopidogrel Actavis for as long as your doctor prescribes it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Clopidogrel Actavis<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose of&nbsp;Clopidogrel Actavis and discover it within 12 hours, take the tablet as soon as you notice and take the next tablet at the usual time.<br><\/p>\n\n\n\n<p>If it takes more than 12 hours before you discover it, simply take the next daily&nbsp;dose at the usual time.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<br><\/p>\n\n\n\n<p>For pack sizes of 14, 28 56, 84, and 98 tablets, you can check which day you last took a Clopidogrel Actavis tablet by looking at the calendar printed on the blister.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Clopidogrel Actavis<\/h2>\n\n\n\n<p>Do not stop treatment unless your doctor tells you to.&nbsp;Contact a doctor or pharmacist before stopping treatment.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Contact your doctor immediately if you have:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever, signs of&nbsp;infection,&nbsp;or severe weakness.&nbsp;This may be due to a rare decrease in certain&nbsp;blood cells.<\/li><li>signs of liver problems such as yellowing of the skin and\/or eyes (jaundice), with or without concomitant small punctate hemorrhages under the skin (visible as red dots), and\/or confusion (see section 2 \u201cWarnings and precautions\u201d).<\/li><li>swelling of the mouth or skin problems such as rash and&nbsp;itching, blisters on the skin.&nbsp;This may be a sign of an&nbsp;allergic reaction.<\/li><\/ul>\n\n\n\n<p><strong>The most common&nbsp;side effect&nbsp;reported with Clopidogrel Actavis is bleeding.<\/strong><\/p>\n\n\n\n<p>Bleeding can occur as bleeding in the stomach or intestines, bruising, hematoma (unusual bleeding or bruising under the skin), nosebleeds, blood in the urine.&nbsp;In a few cases, bleeding in the eye, internal bleeding in the head, lungs, or joints have also been reported.<br><\/p>\n\n\n\n<p><strong>If you experience prolonged bleeding while taking Clopidogrel Actavis<\/strong><\/p>\n\n\n\n<p>If you cut or injure yourself, it may take longer than usual for the bleeding to stop.&nbsp;This is linked to how your medicine works because it prevents the formation of blood clots.&nbsp;This normally has no significance for minor cuts and injuries, such as if you cut yourself when shaving.&nbsp;However, if you are concerned about your bleeding, contact your doctor immediately (see section 2 &#8220;Warnings and precautions&#8221;).<br><\/p>\n\n\n\n<p><strong>Other side effects&nbsp;<\/strong><strong>include:<\/strong><\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<p>Diarrhea, abdominal pain, indigestion, or heartburn.<br><\/p>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people): Headache,&nbsp;stomach ulcer, vomiting, nausea, constipation, increased gas in the stomach or intestines, rash,&nbsp;itching, dizziness, tingling, or numbness.<br><\/p>\n\n\n\n<p>Rare (may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<p>Dizziness, enlarged breasts in men.<br><\/p>\n\n\n\n<p>Very rare (may affect up to 1 in 10,000 people): Jaundice, severe abdominal pain with or without back pain, fever, difficulty breathing sometimes while coughing, generalized (widespread) allergic reactions (for example, a feeling of heat with sudden discomfort until fainting), swelling of the mouth, blisters on the skin, skin allergy, pain in the mouth (&nbsp;stomatitis&nbsp;), decreased&nbsp;blood pressure, confusion, hallucinations, joint pain, muscle aches, taste changes, loss of taste.<br><\/p>\n\n\n\n<p>Has been reported (occurs in an unknown number of users):<\/p>\n\n\n\n<p>Hypersensitivity reaction&nbsp;you with chest pain or abdominal pain, signs of persistent low blood sugar.<br><\/p>\n\n\n\n<p>In addition, your doctor may find changes in your blood or urine tests.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Clopidogrel Actavis<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is a clopidogrel result.&nbsp;Each tablet contains 75 mg of clopidogrel.<\/li><li>The other ingredients are Tablet core:&nbsp;lactose, microcrystalline cellulose, crospovidone type A, glycerol behenate, talc.&nbsp;Tablet coating: polyvinyl alcohol, talc, macrogol 3350, lecithin (soybean oil) (E 322), titanium dioxide (E 171), red iron oxide (E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Film-coated tablet.<\/p>\n\n\n\n<p>Pink, 9 mm, round, biconvex, film-coated tablet, embossed with &#8220;II&#8221; on one side.<br><\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<p>Blisters: 10, 20, 28, 30, 50 x 1 (single dose), 56, 60, 84, 98 and 100 tablets.<\/p>\n\n\n\n<p>Tablet jar: 100 tablets<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>IS-220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Actavis Ltd.<\/p>\n\n\n\n<p>BLB016 Bulebel Industrial Estate<\/p>\n\n\n\n<p>Zejtun ZTN 3000<\/p>\n\n\n\n<p>Malta<br><\/p>\n\n\n\n<p>Balkanpharma &#8211; Dupnitsa AD<\/p>\n\n\n\n<p>3, Samokovsko Shosse Str.<\/p>\n\n\n\n<p>2600 Dupnitsa<\/p>\n\n\n\n<p>Bulgaria<br><\/p>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 78<\/p>\n\n\n\n<p>IS-220 Hafnarfjordur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clopidogrel Actavis contains clopidogrel and belongs to a group of medicines called platelet inhibitors. Platelets are very small cells in the blood, which form clots ( clots ) when the blood coagulates (blood clots). By preventing this clot formation, platelet inhibitors reduce the risk of blood clots forming (a process known as thrombosis or blood clot formation).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[6906,6944,6946,6947,6908,6909,6910,6948,6943,6945],"class_list":["post-6901","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-clopidogrel","tag-clopidogrel-actavis","tag-clopidogrel-actavis-side-effects","tag-clopidogrel-actavis-tablet","tag-clopidogrel-side-effects","tag-clopidogrel-tablet","tag-side-effects-of-clopidogrel","tag-side-effects-of-clopidogrel-actavis","tag-waht-is-clopidogrel","tag-what-is-clopidogrel-actavis"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6901"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6901\/revisions"}],"predecessor-version":[{"id":11356,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6901\/revisions\/11356"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}