{"id":6763,"date":"2021-01-13T09:20:23","date_gmt":"2021-01-13T09:20:23","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6763"},"modified":"2021-06-09T07:12:11","modified_gmt":"2021-06-09T07:12:11","slug":"cinqaero","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/cinqaero\/","title":{"rendered":"Cinqaero &#8211; Reslizumab uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n10 mg \/ ml concentrate for solution for infusion&nbsp;<br>reslizumab<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What CINQAERO is and what it is used for<\/h2>\n\n\n\n<p><strong>What CINQAERO is<\/strong><\/p>\n\n\n\n<p>CINQAERO is a medicine that contains the active substance reslizumab (a monoclonal&nbsp;antibody&nbsp;) which is a type of&nbsp;protein&nbsp;that recognizes and binds to a specific target substance in the body.<br><\/p>\n\n\n\n<p><strong>How CINQAERO works<\/strong><\/p>\n\n\n\n<p>CINQAERO blocks&nbsp;interleukin&nbsp;\u20115 \u2011 activity and reduces the number of&nbsp;eosinophils&nbsp;in the blood and lungs.&nbsp;Eosinophils&nbsp;are&nbsp;white blood cells&nbsp;that are involved in asthmatic&nbsp;inflammation.&nbsp;Interleukin&nbsp;\u20115 is a&nbsp;protein&nbsp;produced by the body that plays an important role in asthmatic&nbsp;inflammation&nbsp;by activating&nbsp;eosinophils.<br><\/p>\n\n\n\n<p><strong>What CINQAERO is used for<\/strong><\/p>\n\n\n\n<p>CINQAERO is used to treat severe&nbsp;eosinophilic&nbsp;asthma&nbsp;in adult patients (18 years and older) when the condition is not well controlled despite high-dose&nbsp;treatment with&nbsp;inhaled&nbsp;corticosteroids&nbsp;with another asthma medicine.&nbsp;Eosinophilic&nbsp;asthma&nbsp;is a type of&nbsp;asthma&nbsp;that means that patients have too many&nbsp;eosinophils&nbsp;in their blood or lungs.&nbsp;CINQAERO is used with other medicines to treat&nbsp;asthma&nbsp;(inhaled&nbsp;corticosteroids&nbsp;plus other asthma medicines).<br><\/p>\n\n\n\n<p><strong>What are the benefits of CINQAERO?<\/strong><\/p>\n\n\n\n<p>CINQAERO reduces how often you may experience worsening asthma symptoms, helps you breathe better, and reduces your asthma symptoms.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you get CINQAERO<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not receive CINQAERO:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to reslizumab or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before receiving CINQAERO:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have a parasitic infection or if you live in an area where parasitic infections are common or if you travel to such an area as this medicine may reduce your body&#8217;s ability to fight certain types of parasitic infections.<br><\/li><\/ul>\n\n\n\n<p>Also, talk to a doctor or nurse when receiving CINQAERO:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if asthma is still out of control or if it worsens during treatment with this medicine.<\/li><li>if you have any symptoms of an&nbsp;allergic reaction&nbsp;(eg&nbsp;itching, difficulty breathing, wheezing, fever, chills, dizziness, headache, nausea, vomiting, abdominal discomfort, rash,&nbsp;redness,&nbsp;or swelling).&nbsp;Serious allergic reactions have occurred in patients receiving this medicine (see section \u201c4. Possible side effects\u201d).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This is NOT for use in children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and CINQAERO<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>This is especially important:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are taking other medicines that affect the immune system<\/li><li>if you have recently been vaccinated or if you are likely to need to be vaccinated.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>The active substance in this medicine may pass into breast milk but only during the first days after birth.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>CINQAERO is unlikely to affect your ability to drive and use machines.<br><\/p>\n\n\n\n<p><strong>CINQAERO contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, ie essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How CINQAERO is given<\/h2>\n\n\n\n<p>Always follow your doctor&#8217;s instructions.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Dose&nbsp;one depends on your body weight.&nbsp;The doctor will calculate which&nbsp;dose&nbsp;is right for you.&nbsp;The highest&nbsp;dose&nbsp;is 3 mg\/kg body weight.&nbsp;CINQAERO is given every 4 weeks.&nbsp;CINQAERO is given by a doctor or nurse as&nbsp;an infusion&nbsp;(drip) into a vein.&nbsp;Infusion&nbsp;one takes about 20 to 50 minutes.<br><\/p>\n\n\n\n<p>You may need more than one&nbsp;dose&nbsp;before your asthma symptoms improve.<br><\/p>\n\n\n\n<p>Your doctor or nurse will monitor you closely during and after the&nbsp;infusion&nbsp;for signs of an&nbsp;allergic reaction.<br><\/p>\n\n\n\n<p><strong>If you miss a&nbsp;dose&nbsp;of CINQAERO<\/strong><\/p>\n\n\n\n<p>If you have missed a planned&nbsp;dose&nbsp;of CINQAERO, ask your doctor when you should receive the next treatment.<br><\/p>\n\n\n\n<p><strong>If you stop using CINQAERO<\/strong><\/p>\n\n\n\n<p>DO NOT stop treatment with CINQAERO unless your doctor tells you to, even if you feel better.&nbsp;If you stop or stop taking this medicine, your asthma symptoms may return.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Severe allergic reactions<\/strong> are uncommon (may affect up to 1 in 100 people) during or after administration of CINQAERO.&nbsp;Your doctor or nurse will monitor you closely for signs of a reaction.&nbsp;Tell&nbsp;your doctor or nurse&nbsp;<strong><em>immediately<\/em><\/strong>&nbsp;if you get any symptoms of an&nbsp;allergic reaction&nbsp;(eg&nbsp;itching, difficulty breathing, wheezing, fever, chills, dizziness, headache, nausea, vomiting, abdominal discomfort, skin rash,&nbsp;redness,&nbsp;or swelling).<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The increased amount of an&nbsp;enzyme&nbsp;in the blood (blood creatine phosphokinase)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle pain (&nbsp;myalgia&nbsp;)<br><\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.<a href=\"javascript:void(0);\">&nbsp;<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store CINQAERO<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the outer carton and label after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C&nbsp;<strong>&#8211;<\/strong>&nbsp;8 \u00b0 C).&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Keep the vial in the outer carton.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is reslizumab.One ml concentrate contains 10 mg reslizumab (10 mg \/ ml).&nbsp;A&nbsp;vial&nbsp;of 2.5 ml contains 25 mg reslizumab and a&nbsp;vial&nbsp;of 10 ml contains 100 mg reslizumab.<\/li><li>The other ingredients are sodium acetate, concentrated acetic acid, sucrose, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>CINQAERO is a clear to slightly opalescent, colorless to light yellow concentrate for&nbsp;solution&nbsp;for&nbsp;infusion&nbsp;(sterile concentrate).&nbsp;Particles may be present.&nbsp;CINQAERO is supplied in glass vials containing 2.5 ml or 10 ml.<br><\/p>\n\n\n\n<p>CINQAERO is available in packs containing 1 or 2 2.5 ml vials and in packs containing 1 or 2 10 ml vials.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Teva BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>2031 GA Haarlem<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>UAB Teva Baltics<\/p>\n\n\n\n<p>Mol\u0117t\u0173 pl.&nbsp;5<\/p>\n\n\n\n<p>LT \u2011 08409 Vilnius<\/p>\n\n\n\n<p>Lithuania<br><\/p>\n\n\n\n<p>Merckle GmbH<\/p>\n\n\n\n<p>Graf-Arco-Str.&nbsp;3<\/p>\n\n\n\n<p>89079 Ulm<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Teva Pharma Belgium NV \/ SA \/ AGTel: +32 3 820 73 73<\/td><td><strong>Lithuania<\/strong>UAB Teva BalticsTel: +370 5 266 0203<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Teva Pharmaceuticals Bulgaria \u0415\u041e\u041e\u0414Tel: +359 2 489 95 82<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>Teva Pharma Belgium NV \/ SA \/ AGTel: +32 3 820 73 73<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Teva Pharmaceuticals CR, sroTel: +420 251 007 111<\/td><td><strong>Hungary<\/strong>Teva Gy\u00f3gyszergy\u00e1r Zrt.Tel .: +36 1 288 64 00<\/td><\/tr><tr><td><strong>Denmark<\/strong>Teva Denmark A \/ STel: +45 44 98 55 11<\/td><td><strong>Malta<\/strong>Teva Pharmaceuticals Ireland, L \u2011 IrelandTel: +353 51 321740<\/td><\/tr><tr><td><strong>Germany<\/strong>TEVA GmbHTel: +49 731 402 08<\/td><td><strong>The Netherlands<\/strong>Teva Nederland BVTel: +31 800 0228 400<\/td><\/tr><tr><td><strong>Eesti<\/strong>UAB Teva Baltics Eesti subsidiaryTel: +372 661 0801<\/td><td><strong>Norway<\/strong>Teva Norway ASTel: +47 66 77 55 90<\/td><\/tr><tr><td><strong>Greece<\/strong>Teva \u0391\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395.:\u0397\u03bb: +30 211 880 5000<\/td><td><strong>Austria<\/strong>ratiopharm Arzneimittel Vertriebs \u2011 GmbHTel: +43 1 97 007<\/td><\/tr><tr><td><strong>Spain<\/strong>Teva Pharma, SLUTel: +34 91 387 32 80<\/td><td><strong>Poland<\/strong>Teva Pharmaceuticals Polska Sp.&nbsp;z ooTel .: +48 22 345 93 00<\/td><\/tr><tr><td><strong>France<\/strong>Teva HealthTel: +33 1 55 91 78 00<\/td><td><strong>Portugal<\/strong>Teva Pharma &#8211; Pharmaceutical Products, LdaTel: +351 21 476 75 50<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pliva Hrvatska dooTel: +385 1 37 20 000<\/td><td><strong>Romania<\/strong>Teva Pharmaceuticals SRLTel: +40 21 230 65 24<\/td><\/tr><tr><td><strong>Ireland<\/strong>Teva Pharmaceuticals IrelandTel: +353 51 321740<\/td><td><strong>Slovenia<\/strong>Pliva Ljubljana dooTel: +386 1 58 90 390<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hfPhone: +354 535 7000<\/td><td><strong>Slovak Republic<\/strong>TEVA Pharmaceuticals Slovakia sroTel: +421 2 57 26 79 11<\/td><\/tr><tr><td><strong>Italy<\/strong>Teva Italia SrlTel: +39 02 89 17 98 1<\/td><td><strong>Finland \/ Finland<\/strong>Teva Finland OyPuh \/ Tel: +358 20 180 5900<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>Teva \u0391\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395., .\u03bb\u03bb\u03ac\u03b4\u03b1:\u0397\u03bb: +30 211 880 5000<\/td><td><\/td><\/tr><tr><td><strong>Latvia<\/strong>UAB Teva Baltics subsidiary Latvij\u0101Tel: +371 673 23 666<\/td><td><strong>UK<\/strong>Teva UK LimitedTel: +44 1977 628500<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>CINQAERO is a medicine that contains the active substance reslizumab (a monoclonal antibody ) which is a type of protein that recognizes and binds to a specific target substance in the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7227,7231,7229,7230,2212,7222,7226,7224,7225,7228,7223],"class_list":["post-6763","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-cinqaero","tag-cinqaero-dose","tag-cinqaero-side-effects","tag-cinqaero-uses","tag-medicine","tag-reslizumab","tag-reslizumab-dose","tag-reslizumab-side-effects","tag-reslizumab-uses","tag-what-is-cinqaero","tag-what-is-reslizumab"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6763"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6763\/revisions"}],"predecessor-version":[{"id":11451,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6763\/revisions\/11451"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}