{"id":6697,"date":"2021-01-12T10:35:12","date_gmt":"2021-01-12T10:35:12","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6697"},"modified":"2021-06-09T07:46:15","modified_gmt":"2021-06-09T07:46:15","slug":"ciastad","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ciastad\/","title":{"rendered":"Ciastad &#8211; Tadalafil uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n20 mg&nbsp;film-coated tablets&nbsp;<br>tadalafil<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Ciastad is and what it is used for<\/h2>\n\n\n\n<p>Ciastad contains the active substance tadalafil.<br><\/p>\n\n\n\n<p>Ciastad is a treatment for&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;in adults.<br><\/p>\n\n\n\n<p>It belongs to a group of drugs called&nbsp;phosphodiesterase&nbsp;type 5 inhibitors (PDE5), which improve blood flow to the lungs by affecting the blood vessels around the lungs so that they relax.&nbsp;The result is improved capacity during physical exertion.<br><\/p>\n\n\n\n<p>Tadalafil contained in Ciastad may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Ciastad<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Ciastad<\/h2>\n\n\n\n<p><strong>Do not take Ciastad if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>is allergic to tadalafil or any of the other ingredients of this medicine (listed in section 6)<\/li><li>take medicines that contain nitrates such as amyl nitrite, which are used to treat chest pain.&nbsp;Tadalafil has been shown to increase the effectiveness of these drugs.&nbsp;If you are taking any form of nitrate or are unsure, talk to your doctor<\/li><li>have ever before lost their sight &#8211; a condition called &#8220;stroke in the eye&#8221; (non-arteritic anterior ischemic optic neuropathy &#8211; NAION).<\/li><li>have had a heart attack in the last 3 months<\/li><li>have low&nbsp;blood pressure<\/li><li>tar riociguat.&nbsp;This medicine is used to treat&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;(ie high&nbsp;blood pressure&nbsp;in the lungs) and&nbsp;chronic&nbsp;thromboembolic&nbsp;pulmonary hypertension&nbsp;(ie high&nbsp;blood pressure&nbsp;in the lungs due to blood clots).&nbsp;PDE5 inhibitors, such as tadalafil, have been shown to increase the antihypertensive effect of this medicine.&nbsp;If you are taking riociguat or if you are not sure, talk to your doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Ciastad.<br><\/p>\n\n\n\n<p>Before taking the tablets, tell your doctor if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>heart problems other than your high&nbsp;blood pressure&nbsp;in the lungs<\/li><li>problems with your&nbsp;blood pressure<\/li><li>any hereditary eye disease<\/li><li>abnormal&nbsp;red blood cells&nbsp;(sickle cell anemia)<\/li><li>bone marrow&nbsp;cancer&nbsp;(multiple&nbsp;myeloma&nbsp;)<\/li><li>blood cell cancer (&nbsp;leukemia&nbsp;)<\/li><li>a deformed penis, or an unwanted or persistent&nbsp;erection&nbsp;that lasts for more than 4 hours<\/li><li>severe liver disease<\/li><li>severe kidney disease.<\/li><\/ul>\n\n\n\n<p>If you experience a sudden visual impairment or loss of vision, contact your doctor immediately.<br><\/p>\n\n\n\n<p>Impaired hearing or sudden hearing loss has been noted in some patients taking tadalafil.&nbsp;Although it is not known if the events are related to tadalafil, you should contact your doctor immediately if you experience hearing loss or sudden hearing loss.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Ciastad should not be given to children or adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ciastad<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>DO NOT take this medicine if you are already taking nitrates.<br><\/p>\n\n\n\n<p>Some medicines may be affected by Ciastad or they may affect Ciastad&#8217;s effect.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are already taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>bosentan&nbsp;(another medicine used to treat&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;)<\/li><li>nitrates (for chest pain)<\/li><li>alpha-blockers used to treat high&nbsp;blood pressure&nbsp;or prostate problems<\/li><li>riociguat<\/li><li>rifampicin (to treat bacterial infections)<\/li><li>ketoconazole tablets (to treat fungal infections)<\/li><li>ritonavir (for&nbsp;HIV&nbsp;treatment)<\/li><li>tablets for&nbsp;erectile dysfunction&nbsp;(PDE5 inhibitors).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ciastad with food, drink, and alcohol<\/h2>\n\n\n\n<p>Alcohol intake can temporarily lower your&nbsp;blood pressure.&nbsp;Avoid consuming large amounts of alcohol (over 5 units of alcohol) when you have taken or plan to take Ciastad as this may increase the risk of dizziness when standing up.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p>Do not take Ciastad during pregnancy unless clearly necessary and you have discussed this with your doctor.<br><\/p>\n\n\n\n<p>Do not breast-feed while taking these tablets, as it is not known if the medicine passes into human breast milk.&nbsp;Ask your doctor or pharmacist for advice before taking any medicine during pregnancy or breast-feeding.<br><\/p>\n\n\n\n<p>Dogs that were treated had&nbsp;reduced&nbsp;sperm development in the testicles.&nbsp;Reduced sperm concentration has been shown in some men.&nbsp;Its effects are unlikely to impair&nbsp;male fertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Dizziness has been reported.&nbsp;Know how you react to the medicine before driving or using machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ciastad contains lactose and sodium<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie&nbsp;essentially &#8216;sodium-free&#8217;.&nbsp;is next to &#8220;sodium-free&#8221;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Ciastad<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Ciastad is supplied as a 20 mg tablet.&nbsp;The usual dose is two 20 mg tablets once a day.&nbsp;You should take both tablets at the same time, one after the other.&nbsp;Your doctor may have prescribed you only one 20 mg tablet daily if you have mild to moderate liver or kidney problems.<br><\/p>\n\n\n\n<p>Swallow the tablets with a little water.&nbsp;You can take the tablets regardless of the meal.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Ciastad<\/h2>\n\n\n\n<p>Take a&nbsp;dose&nbsp;as soon as you remember it if it is within 8 hours of you taking your&nbsp;dose.&nbsp;DO NOT take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Ciastad<\/h2>\n\n\n\n<p>Do not stop taking your tablets unless your doctor has told you to.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;The side effects&nbsp;are usually mild or moderate in nature.<br><\/p>\n\n\n\n<p><strong>If you get any of the following&nbsp;side effects, stop using the medicine and see a doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions with a rash (uncommon)<\/li><li>chest pain &#8211; do not use nitrates but see a doctor immediately (common)<\/li><li>priapism, a prolonged and possibly painful&nbsp;erection&nbsp;after taking Ciastad (rare).&nbsp;If you get&nbsp;an erection&nbsp;that lasts continuously for more than 4 hours, you should contact a doctor immediately<\/li><li>sudden loss of vision (rare).<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported very commonly in patients taking tadalafil (may affect more than 1 in 10 people): headache,&nbsp;redness, nasal congestion, and blocked sinuses, nausea, indigestion (including abdominal pain), muscle aches, back pain and pain or discomfort in the arms and bones.<br><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;have been reported:<br><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blurred vision, low&nbsp;blood pressure, nosebleeds, vomiting, increased or abnormal abdominal bleeding, facial swelling, acid regurgitation,&nbsp;migraine&nbsp;, irregular heartbeat, and fainting.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>seizures, temporary memory loss,&nbsp;hives, profuse sweating, bleeding from the penis, presence of blood in semen and\/or urine, high&nbsp;blood pressure, palpitations, sudden cardiac death, and&nbsp;tinnitus&nbsp;(sound in the ears without external sound source).<\/li><\/ul>\n\n\n\n<p><strong>PDE5 inhibitors<\/strong>&nbsp;are also used to treat&nbsp;erectile dysfunction&nbsp;in men.&nbsp;Some&nbsp;side effects reported rarely:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Partial, temporary, or permanent vision loss or loss of vision in one or both eyes and severe&nbsp;allergic reaction&nbsp;that causes swelling of the face and throat.&nbsp;Sudden deterioration or loss of hearing has also been reported.<\/li><\/ul>\n\n\n\n<p>Some&nbsp;side effects&nbsp;have been reported in men taking tadalafil for the treatment of&nbsp;erectile dysfunction.<\/p>\n\n\n\n<p>These&nbsp;side effects&nbsp;have not been reported in&nbsp;clinical trials&nbsp;of&nbsp;pulmonary&nbsp;arterial hypertension&nbsp;and therefore the frequency is unknown:<\/p>\n\n\n\n<p>swollen eyelids, pain in the eyes, red eyes, heart attack, and&nbsp;stroke.<br><\/p>\n\n\n\n<p>Most, but not all, men who reported palpitations, irregular heartbeats, heart attacks,&nbsp;strokes,&nbsp;and sudden cardiac death had known heart problems before taking the drug.&nbsp;It is not possible to determine whether these reactions were directly related to tadalafil.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Ciastad<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is tadalafil.<\/p>\n\n\n\n<p>One film-coated tablet contains 20 mg of tadalafil.<br><\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p><strong>Tablet core: anhydrous&nbsp;lactose, croscarmellose sodium, sodium lauryl sulfate, hydroxypropyl cellulose<\/strong>, polysorbate 80, magnesium stearate.<\/p>\n\n\n\n<p><strong>Film coating<\/strong>: hypromellose (E464),&nbsp;lactose monohydrate, titanium dioxide (E171), triacetin, talc (E553b), yellow iron oxide (E172).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Yellow, capsule-shaped, biconvex, film-coated tablet, marked with &#8220;T 20&#8221; on one side and smooth on the other.<br><\/p>\n\n\n\n<p>Available in blister packs containing 14, 28, or 56 tablets.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>Other manufacturers<\/strong><\/p>\n\n\n\n<p>Genepharm SA<\/p>\n\n\n\n<p>18th Km Marathonos Avenue<\/p>\n\n\n\n<p>Pallini Attiki<\/p>\n\n\n\n<p>Greece<br><\/p>\n\n\n\n<p>Pharmadox Healthcare Ltd<\/p>\n\n\n\n<p>1KW20A Kordin Industrial Park<\/p>\n\n\n\n<p>PLA 3000<\/p>\n\n\n\n<p>Malta<br><\/p>\n\n\n\n<p>Combino Pharm Ltd.<\/p>\n\n\n\n<p>HF60, Hal Far Industrial Estate BBG3000<\/p>\n\n\n\n<p>Malta<br><\/p>\n\n\n\n<p>Centrafarm Services BV<\/p>\n\n\n\n<p>New Donk 9<\/p>\n\n\n\n<p>4879 AC Etten-Leur<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ciastad contains the active substance tadalafil.. Ciastad is a treatment for pulmonary arterial hypertension in adults.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7302,7304,7305,2212,2211,7298,7300,7301,7303,7299],"class_list":["post-6697","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-ciastad","tag-ciastad-side-effects","tag-ciastad-tablet","tag-medicine","tag-tablets","tag-tadalafil","tag-tadalafil-side-effects","tag-tadalafil-tablet","tag-what-is-ciastad","tag-what-is-tadalafil"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6697"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6697\/revisions"}],"predecessor-version":[{"id":11473,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6697\/revisions\/11473"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}