{"id":6687,"date":"2021-01-12T10:28:06","date_gmt":"2021-01-12T10:28:06","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6687"},"modified":"2021-06-11T13:23:37","modified_gmt":"2021-06-11T13:23:37","slug":"chirocaine","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/chirocaine\/","title":{"rendered":"Chirocaine &#8211; Levobupivacaine uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n0.625 mg \/ ml and 1.25 mg \/ mL&nbsp;infusion&nbsp;solution&nbsp;<br>levobupivacaine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Chirocaine is and what it is used for<\/h2>\n\n\n\n<p>Chirocaine belongs to a group of medicines called&nbsp;local anesthetics.&nbsp;This type of medicine is used to numb or relieve a part of the body.<br><\/p>\n\n\n\n<p>Chirocaine&nbsp;infusion&nbsp;solution&nbsp;<strong>must be used only in adults.<\/strong><br><\/p>\n\n\n\n<p>Chirocaine is used for pain relief:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>after major surgeries<\/li><li>at births<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you are given Chirocaine<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Chirocaine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to levobupivacaine, to similar&nbsp;local anesthetics to any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have very low&nbsp;blood pressure<\/li><li>as a type of pain relief given by&nbsp;injection&nbsp;in the area around the cervix (&nbsp;cervix&nbsp;) during the opening stage of labor (paracervical blockade)<\/li><li>to numb an area by injecting Chirocaine into a vein<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Before treatment with Chirocaine, tell your doctor or nurse if you suffer from any of the conditions or any of the conditions listed below.&nbsp;You may need to be monitored more closely or you may need to be given a smaller&nbsp;dose.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have diseases of the nervous system<\/li><li>if you are weak or ill<\/li><li>if you are older<\/li><li>if you have liver disease.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Chirocaine<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you are taking or have recently taken or might take any other medicines.&nbsp;Be especially careful to tell if you are taking medicines for:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>irregular heartbeat (eg mexiletine)<\/li><li>fungal infections (eg&nbsp;ketoconazole&nbsp;) as it may affect how long Chirocaine stays in the body<\/li><li>asthma&nbsp;(eg theophylline) because it can affect how long Chirocaine stays in the body<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant, breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or nurse for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Chirocaine must not be given as pain relief by&nbsp;injection&nbsp;in the area around the cervix (&nbsp;cervix&nbsp;) during childbirth (paracervical blockade).<br><\/p>\n\n\n\n<p>The effect of Chirocaine on the baby during early pregnancy is unknown.&nbsp;Therefore, Chirocaine should not be used during the first three months of pregnancy unless your doctor considers it necessary.<br><\/p>\n\n\n\n<p>It is not known if levobupivacaine is transferred to breast milk, but experience with a similar drug shows that only small amounts of levobupivacaine are expected to be transferred to breast milk.&nbsp;It is therefore possible to breastfeed after using Chirocaine as a&nbsp;local anesthetic.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Chirocaine can have significant effects on the ability to drive and use machines.&nbsp;You must not drive or use machines until all effects of Chirocaine and the immediate effects of the operation have ceased.&nbsp;Consult the doctor or nurse treating you before leaving the hospital.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Chirocaine contains sodium<\/h2>\n\n\n\n<p>This medicine contains 3.5 mg\/ml&nbsp;sodium&nbsp;in an&nbsp;infusion bag&nbsp;or&nbsp;ampoule, which should be considered by patients on a low-salt diet.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to get Chirocaine<\/h2>\n\n\n\n<p>The doctor gives Chirocaine through a small tube in the back (epidural).&nbsp;Your doctor and nurse will monitor you closely when you receive Chirocaine.<br><\/p>\n\n\n\n<p><strong>Dosage<\/strong><br><\/p>\n\n\n\n<p>Adults:<\/p>\n\n\n\n<p>The amount and how often Chirocaine is given depends on why Chirocaine is used and on your health, age, and weight.&nbsp;The minimum&nbsp;dose&nbsp;that can generate anesthesia in the intended area will be used.&nbsp;Dosage&nbsp;one is carefully prepared by the doctor.<br><\/p>\n\n\n\n<p>When Chirocaine is used for pain relief during childbirth, the&nbsp;dose&nbsp;should be&nbsp;monitored particularly carefully.<br><\/p>\n\n\n\n<p>Children:<\/p>\n\n\n\n<p>Not recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Chirocaine than you should<\/h2>\n\n\n\n<p>If you are given too much Chirocaine, you may experience numbness of the tongue, dizziness, blurred vision, muscle twitching, severe difficulty breathing (including pauses in breathing), and seizures.&nbsp;Tell your doctor immediately if you notice any of these symptoms.&nbsp;In some cases, too much Chirocaine can cause low&nbsp;blood pressure, fast or slow heartbeat, and changes in heart rate.&nbsp;Your doctor may need to give you other medicines to relieve these symptoms.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.&nbsp;Some&nbsp;side effects&nbsp;of Chirocaine can be serious.<br><\/p>\n\n\n\n<p>If you notice any of the following&nbsp;side effects, contact your doctor or nurse immediately.<br><\/p>\n\n\n\n<p>Very common: may affect more than 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feelings of fatigue or weakness, shortness of breath, pallor (all of these are signs of&nbsp;anemia&nbsp;)<\/li><\/ul>\n\n\n\n<p>Common: may affect up to 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>complications (discomfort) for an unborn child<\/li><\/ul>\n\n\n\n<p>No known frequency: frequency can not be calculated from the available data<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe allergic reactions (hypersensitivity) that cause difficulty breathing, difficulty swallowing, rash, very low&nbsp;blood pressure,&nbsp;and swelling of the tongue or throat<\/li><li>respiratory arrest<\/li><li>heart block or cardiac arrest<\/li><li>unconsciousness<\/li><li>paralysis<\/li><li>seizures<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that may also occur:<\/p>\n\n\n\n<p>Very common: may affect more than 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low&nbsp;blood pressure<\/li><li>nausea<\/li><\/ul>\n\n\n\n<p>Common: may affect up to 1 in 10 people<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>headache<\/li><li>vomiting<\/li><li>back pain<\/li><li>high body temperature (fever)<\/li><li>pain after surgery<\/li><\/ul>\n\n\n\n<p>No known frequency: frequency can not be calculated from the available data<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions (hypersensitivity) characterized by red, itchy skin, sneezing, profuse sweating, rapid heartbeat, fainting, or swelling of the face, lips, and mouth.<\/li><li>somnolence<\/li><li>dimsyn<\/li><li>localized knitting<\/li><li>numbness of the tongue<\/li><li>muscle weakness or muscle twitching<\/li><li>lost control of the&nbsp;bladder&nbsp;and intestines<\/li><li>tingling, numbness, or other abnormal sensations<\/li><li>prolonged&nbsp;erection&nbsp;of the penis which can be painful<\/li><li>nerve disease that may include drooping eyelids, small eye pupils, sunken eye socket, sweating, and\/or unilateral&nbsp;redness&nbsp;of the face.<\/li><\/ul>\n\n\n\n<p>Rapid, slow, or irregular heartbeats and changes in heart rate that can be seen on an&nbsp;ECG&nbsp;have also been reported as&nbsp;side effects.<br><\/p>\n\n\n\n<p>In rare cases, some&nbsp;side effects&nbsp;may be long-lasting or permanent.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Chirocaine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the label.&nbsp;The expiration date is the last day of the specified month.<\/li><li>This medicine is stored by your doctor.<\/li><li>The solution should be used immediately after opening the package.<\/li><li>The solution must not be used if there are visible particles in it.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is levobupivacaine (as hydrochloride).<br><\/p>\n\n\n\n<p>Chirocaine 0.625 mg \/ ml&nbsp;solution for infusion&nbsp;: One ml contains 0.625 mg levobupivacaine (as hydrochloride).<br><\/p>\n\n\n\n<p>Chirocaine 1.25 mg \/ ml&nbsp;solution for infusion&nbsp;: One ml contains 1.25 mg levobupivacaine (as hydrochloride).<br><\/p>\n\n\n\n<p>The other ingredients are water for injections, sodium chloride, sodium hydroxide, and a small amount of&nbsp;hydrochloric acid.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Chirocaine is a clear, colorless solution in a soft polyester bag with an aluminum outer bag.&nbsp;Each bag contains 100 ml or 200 ml of solution.&nbsp;Chirocaine is delivered in packs of 5 bags with 100 ml or 200 ml solution, 24 or 60 bags with 100 ml solution, and 12 or 32 bags with 200 ml solution.&nbsp;Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>AbbVie AB&nbsp;<br>Box 1523<\/p>\n\n\n\n<p>171 29 Solna<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Baxter Healthcare SA, Moneen Road, Castlebar, Ireland<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p><strong>Chirocaine:<\/strong>&nbsp;Italy, Netherlands, France, UK, Ireland, Finland, Greece, Belgium, Luxembourg.<\/p>\n\n\n\n<p><strong>Chirocane:<\/strong>&nbsp;Spain<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chirocaine belongs to a group of medicines called local anesthetics. This type of medicine is used to numb or relieve a part of the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7350,7354,7352,7353,7345,7349,7348,2212,7351,7346],"class_list":["post-6687","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-chirocaine","tag-chirocaine-dose","tag-chirocaine-side-effects","tag-chirocaine-uses","tag-levobupivacaine","tag-levobupivacaine-dose","tag-levobupivacaine-uses","tag-medicine","tag-what-is-chirocaine","tag-what-is-levobupivacaine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6687"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6687\/revisions"}],"predecessor-version":[{"id":11487,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6687\/revisions\/11487"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}