Fertility<\/strong><\/p>\n\n\n\nCerubidin may affect male and female fertility.
<\/p>\n\n\n\n
Cerubidin can cause chromosomal damage in sperm. If you are a man, you should get advice on freezing sperm before starting Cerubidin treatment.<\/p>\n\n\n\n
Men undergoing treatment must use effective contraception during and up to 6 months after stopping treatment.
<\/p>\n\n\n\n
If you are a woman of childbearing potential, you must use an effective method of contraception during treatment with Cerubidin.
<\/p>\n\n\n\n
If you want to get pregnant after stopping Cerubidine treatment, you should get genetic counseling before starting Cerubidin treatment.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Cerubidin may affect your ability to drive or use machines due to possible side effects of the treatment such as nausea and vomiting.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
<\/p>\n\n\n\n
3. How to use Cerubidin<\/h2>\n\n\n\n
Treatment with Cerubidin takes place in a hospital and should be initiated by or in consultation with a physician with extensive experience in chemotherapy.
<\/p>\n\n\n\n
Cerubidine can be given alone or in combination with other medicines.
<\/p>\n\n\n\n
It is given as an infusion into one of your veins ( intravenously ).<\/p>\n\n\n\n
Tell your doctor or nurse immediately if you feel a burning sensation around the area where Cerubidin is given. This may be because the medicine has ended up outside the infusion site and the infusion should then be stopped and other measures may need to be taken.
<\/p>\n\n\n\n
Dose one is individually adjusted to your body weight. Your doctor will decide how often you should receive treatment depending on how you respond to the medication.
<\/p>\n\n\n\n
Your health condition will be closely monitored during treatment with Cerubidin, which may include blood tests, urine tests, and monitoring of heart function ( ECG ).<\/p>\n\n\n\n
Use for children and adolescents<\/h2>\n\n\n\n
Dosage of Cerubidin in children older than 2 years is usually based on body surface area and is adjusted for each individual patient. Normally the course is repeated after 3-6 weeks.
<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
Stop taking Cerubidin and contact a<\/strong> doctor immediately<\/strong> or see the nearest emergency department if you experience the following symptoms:<\/p>\n\n\n\n- Fever, shortness of breath, or palpitations can be signs of a serious infection, which can sometimes be fatal (eg blood poisoning, septic shock, pneumonia ). (Very common – affects more than 1 user in 10).<\/li>
- If you have heart problems with symptoms such as shortness of breath and swollen legs. (Common – affects more than 1 user in 100).<\/li>
- Allergic reactions ( hypersensitivity reactions ). Symptoms of an allergic reaction may include swelling of the eyelids, face, or lips, low blood pressure, palpitations, sudden itchy rash (hives), sudden wheezing, chest tightness, shortness of breath, and dizziness. (Has been reported – occurs in an unknown number of users).<\/li>
- Diarrhea, abdominal pain, mucus, or blood in the stool, may be a sign of intestinal inflammation ( colitis ). (Has been reported – occurs in an unknown number of users).<\/li><\/ul>\n\n\n\n
Other side effects:<\/strong><\/p>\n\n\n\nVery common<\/em> (affects more than 1 user in 10)<\/p>\n\n\n\n- Blood effects<\/li>
- Bone marrow Effect – Reduced blood formation in the bone marrow one which can give rise to infection s<\/li>
- Impact on the heart muscles<\/li>
- Bleeding<\/li>
- Diarrhea<\/li>
- Inflammation of the esophagus<\/li>
- Inflammation of the oral mucosa or mucous membranes of the esophagus<\/li>
- Nausea\/vomiting<\/li>
- Skin effects (skin rash, redness )<\/li>
- Hair loss<\/li>
- Pain<\/li>
- Laboratory values \u200b\u200bthat are linked to liver function may be affected<\/li><\/ul>\n\n\n\n
Common<\/em> (affects more than 1 user in 100)<\/p>\n\n\n\n- Abdominal pain<\/li>
- Local inflammation in a friend<\/li>
- When measuring heart activity with ECG (electrocardiography), abnormalities can be seen<\/li><\/ul>\n\n\n\n
Uncommon<\/em> (affects less than 1 user in 100)<\/p>\n\n\n\n- Blood cancers (secondary leukemia ) including rapidly progressing blood cancers ( acute myeloid leukemia ) and affecting the white blood cells ( myelodysplastic syndrome ).<\/li>
- Myocardial infarction<\/li><\/ul>\n\n\n\n
Has been reported<\/em> (occurs in an unknown number of users)<\/p>\n\n\n\n- Dehydration<\/li>
- Degradation of cancer cells ( Tumor light syndrome); acute elevated uric acid levels in the blood (with possible impairment of renal function)<\/li>
- Angina pectoris<\/li>
- Increase of the connective tissue in the heart muscle<\/li>
- Myocarditis\/myocarditis<\/li>
- Irregular heartbeat<\/li>
- Feeling of warmth<\/li>
- Shock<\/li>
- Lack of oxygen in tissue are<\/li>
- Liver inflammation<\/li>
- Liver failure<\/li>
- Inflammation of the skin ( contact dermatitis )<\/li>
- Skin itching<\/li>
- Hypersensitivity to irradiated skin (“radiation recall reaction”)<\/li>
- Hyperpigmentation of skin and nails<\/li>
- Hives<\/li>
- Red urine for 1-2 days after administration<\/li>
- Absence of menstruation<\/li>
- Reduced number of sperm ( azoospermia )<\/li>
- Overindulge<\/li>
- That infusion one ends up outside the vein (perivenous extravasation)<\/li>
- Death<\/li>
- Hardening of veins<\/li>
- Inflammation and clot in a superficial vein ( thrombophlebitis )<\/li>
- Thickening of the venous wall (phlebosclerosis)<\/li><\/ul>\n\n\n\n
Reporting of side effects<\/em><\/p>\n\n\n\nIf you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n
5. How to store Cerubidin<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
The solution must be protected from direct sunlight.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton after EXP. That. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Waste that has been in contact with Cerubidin must be handled in accordance with current procedures for hazardous waste. When disposing of any spills, use protective equipment as shown below. Contaminated surfaces are rinsed with copious amounts of water. Glass shards and drying materials are treated as hazardous waste. Residues of Cerubidin can be inactivated with sodium hypochlorite solution if necessary.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is daunorubicin hydrochloride<\/li>
- The other ingredients are mannitol<\/li><\/ul>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
A colorless vial containing 20 mg powder for solution for infusion.<\/p>\n\n\n\n
Pack size: 10 x 20 mg<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/em><\/p>\n\n\n\nSanofi AB, Box 30052, 104 25 Stockholm
<\/p>\n\n\n\n
Manufacturer<\/em><\/p>\n\n\n\nCenexi Laboratories Thissen<\/p>\n\n\n\n
2-6, rue de la Papyr\u00e9e 1420 Braine L\u00b4Alleud<\/p>\n\n\n\n
Belgium
<\/p>\n","protected":false},"excerpt":{"rendered":"
Cerubidin is a medicine used to treat leukemia (cancer of the blood). Drugs used to treat cancer are often called chemotherapy drugs and Cerubidin belongs to a group of chemotherapy drugs called anthracyclines. These work by disrupting the growth of cancer cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7416,7419,7418,7412,7415,7414,2212,2328,7417,7413],"class_list":["post-6663","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-cerubidin","tag-cerubidin-powder","tag-cerubidin-side-effects","tag-daunorubicin","tag-daunorubicin-powder","tag-daunorubicin-side-effects","tag-medicine","tag-powder","tag-what-is-cerubidin","tag-wht-is-daunorubicin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6663","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6663"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6663\/revisions"}],"predecessor-version":[{"id":11509,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6663\/revisions\/11509"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6663"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6663"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6663"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}