{"id":6639,"date":"2021-01-11T13:22:15","date_gmt":"2021-01-11T13:22:15","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6639"},"modified":"2021-06-14T07:49:06","modified_gmt":"2021-06-14T07:49:06","slug":"celsentri","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/celsentri\/","title":{"rendered":"Celsentri &#8211; Maravirok uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n25 mg, 75 mg, 150 mg and 300 mg&nbsp;film-coated tablets&nbsp;<br>maravirok<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What CELSENTRI is and what it is used for<\/h2>\n\n\n\n<p>CELSENTRI contains a substance called maravirok.&nbsp;Maraviroc belongs to a class of drugs called CCR5&nbsp;<em>antagonist&nbsp;you<\/em>&nbsp;.&nbsp;CELSENTRI works by blocking a&nbsp;receptor&nbsp;called CCR5, which&nbsp;HIV&nbsp;uses to enter and infect your blood cells.<br><\/p>\n\n\n\n<p><strong>CELSENTRI is used to treat human immunodeficiency virus type 1 (&nbsp;HIV-&nbsp;1&nbsp;) in adults,&nbsp;<\/strong><strong>adolescents and children from 2 years of age weighing at least 10 kg.<\/strong><br><\/p>\n\n\n\n<p>CELSENTRI must be taken in combination with other drugs that are also used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;a.&nbsp;These medicines&nbsp;<em>are called anti-&nbsp;HIV&nbsp;medicines<\/em>&nbsp;or&nbsp;<em>antiretroviral medicines.<\/em><br><\/p>\n\n\n\n<p>CELSENTRI, as part of a combination treatment, reduces the amount of&nbsp;virus&nbsp;in your body and keeps it at a low level.&nbsp;This helps your body increase the amount of CD4 cells in your blood.&nbsp;CD4 cells are a type of&nbsp;white blood cell&nbsp;that are important in helping your body fight&nbsp;infection&nbsp;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking CELSENTRI<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take CELSENTRI<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you (or your child, if the child is a&nbsp;<em>patient<\/em>&nbsp;) are allergic to maravirok, peanuts, soy or any of the other ingredients of CELSENTRI (&nbsp;<em>listed in section 6<\/em>&nbsp;).<\/li><li>Consult a doctor if you think this applies to you or your child.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking or giving CELSENTRI.<br><\/p>\n\n\n\n<p>Your doctor will take blood samples to see if CELSENTRI is a suitable treatment for you (or your child, if the child is the patient).<br><\/p>\n\n\n\n<p>Some people who have taken CELSENTRI have developed severe allergic reactions or skin reactions (&nbsp;<em>see also \u201cSerious side effects\u201d in section 4<\/em>&nbsp;).<br><\/p>\n\n\n\n<p>Before taking this medicine, make sure that your doctor knows if you (or your child) have or have had any of the following:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>liver problems<\/strong>&nbsp;, including&nbsp;chronic&nbsp;<strong>hepatitis<\/strong>&nbsp;B or C. Only a limited number of people with liver problems have taken CELSENTRI.&nbsp;Your liver function may need to be closely monitored.&nbsp;<em>(See also \u201cLiver problems\u201d in section 4.)<\/em><br><\/li><li><strong>low&nbsp;blood pressure<\/strong>&nbsp;, including dizziness when you set or sit up too fast and \/ or if you are taking any medicine to lower&nbsp;your blood pressure&nbsp;.&nbsp;This is due to a sudden drop in blood pressure.&nbsp;If this happens, you (or your child) should lie down until it feels better.&nbsp;When you (or your child) get up, do it as slowly as possible.<br><\/li><li><strong>tuberculosis<\/strong><strong>&nbsp;(TB)<\/strong>&nbsp;or a serious<strong>&nbsp;fungal infection<\/strong>&nbsp;.&nbsp;CELSENTRI may increase the risk of infection.<br><\/li><li><strong>kidney problems<\/strong>&nbsp;.&nbsp;This is&nbsp;<strong>especially important<\/strong>&nbsp;if you are also taking certain other medicines (see &#8221;&nbsp;<em>Other medicines and CELSENTRI&#8221; later in section 2)<\/em>&nbsp;.<br><\/li><li><strong>problems with the heart or blood circulation<\/strong>&nbsp;.&nbsp;Only a limited number of people with severe heart or circulatory problems have taken CELSENTRI.<\/li><li><strong>Tell your doctor<\/strong>&nbsp;if you think any of these apply to you (or your child) before starting treatment.<br><\/li><\/ul>\n\n\n\n<p><strong>Conditions that you need to be aware of<\/strong><\/p>\n\n\n\n<p>Some people taking medicines for&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;develop other conditions, which can be serious.<\/p>\n\n\n\n<p>These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>symptoms of&nbsp;infection&nbsp;and&nbsp;inflammation<\/li><li>joint pain, stiffness, and skeletal problems.<\/li><\/ul>\n\n\n\n<p>You need to know important signs and symptoms to be aware of while taking CELSENTRI.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Read the information \u201cOther possible&nbsp;side effects&nbsp;of combination therapy for HIV\u201d in section 4 of this leaflet<\/strong>&nbsp;.<br><\/li><\/ul>\n\n\n\n<p><strong>Protect other people<\/strong><\/p>\n\n\n\n<p>HIV&nbsp;&#8211;&nbsp;infection&nbsp;a spread through sexual contact with someone with&nbsp;infection&nbsp;an, or by&nbsp;transfusion&nbsp;of infected blood (for example by sharing needles).&nbsp;You (or your child) can still transmit&nbsp;HIV&nbsp;infection when you take this medicine, even though the risk of effective treatment is reduced.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Talk to your doctor about how to avoid infecting others.<\/li><\/ul>\n\n\n\n<p><strong>Elderly<\/strong><\/p>\n\n\n\n<p>CELSENTRI has only been taken by a limited number of people aged 65 or older.&nbsp;If you belong to this age group, discuss with your doctor if you can use CELSENTRI.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>The use of CELSENTRI has not been tested in children younger than 2 years or weighing less than 10 kg.&nbsp;CELSENTRI is therefore not recommended for use in children younger than 2 years or weighing less than 10 kg.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and CELSENTRI<\/h2>\n\n\n\n<p><strong>Tell your doctor or pharmacist if you (or your child) are taking any other medicines<\/strong>&nbsp;, have recently taken or might be taking any other medicines.<br><\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you (or your child) start taking a new medicine while you are being treated with CELSENTRI.<br><\/p>\n\n\n\n<p>Medicines containing&nbsp;<strong>St. John&#8217;s wort<\/strong>&nbsp;(&nbsp;<em>Hypericum perforatum<\/em>&nbsp;) can probably prevent CELSENTRI from working properly.&nbsp;<strong>You should not take such medicines while taking CELSENTRI.<\/strong><br><\/p>\n\n\n\n<p>Some medicines can change the concentrations of CELSENTRI in the body when taken at the same time as CELSENTRI.&nbsp;These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other drugs for treating&nbsp;<strong>HIV&nbsp;&#8211;<\/strong>&nbsp;or&nbsp;<strong>hepatitis&nbsp;C<\/strong>&nbsp;&#8211;&nbsp;infection&nbsp;(eg atazanavir, kobicistat, darunavir, efavirenz, etravirine, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, boceprevir, telaprevir)<\/li><li><strong>antibiotics<\/strong>&nbsp;(clarithromycin, telithromycin, rifampicin, rifabutin)<\/li><li><strong>medicines for fungal infections<\/strong>&nbsp;(&nbsp;ketoconazole&nbsp;, itraconazole,&nbsp;fluconazole&nbsp;).<\/li><li><strong>antiepileptics<\/strong>&nbsp;(eg carbamazepine,&nbsp;phenytoin&nbsp;, phenobarbital).<\/li><li><strong>Tell your doctor<\/strong>&nbsp;if you (or your child) are taking any of these medicines.&nbsp;The doctor can then&nbsp;prescribe&nbsp;the correct&nbsp;dose&nbsp;one of CELSENTRI.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant, getting pregnant or planning to have children:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Talk to your doctor<\/strong>&nbsp;about the risks and benefits of taking CELSENTRI.<br><\/li><\/ul>\n\n\n\n<p><strong>Women who are&nbsp;HIV&nbsp;-positive should not breast-feed,<\/strong>&nbsp;because&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;one can be transferred to the baby through breast milk.<br><\/p>\n\n\n\n<p>It is not known whether the ingredients in CELSENTRI can also pass into breast milk.&nbsp;If you are breast-feeding or considering starting breast-feeding:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Talk to your doctor immediately.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>CELSENTRI can make you dizzy.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Do not drive, use bicycles or tools or machines<\/strong>&nbsp;unless you are sure you will not be affected.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">CELSENTRI contains soy lecithin and sodium.<\/h2>\n\n\n\n<p>If you are allergic to peanuts or soy, do not use this medicine.<br><\/p>\n\n\n\n<p>CELSENTRI contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie it is essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take CELSENTRI<\/h2>\n\n\n\n<p>Always take or give this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Your doctor will tell you if it is better to take CELSENTRI&nbsp;oral&nbsp;solution if you (or your child) can not swallow tablets.<br><\/p>\n\n\n\n<p><strong>How much to take<\/strong><br><\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;of CELSENTRI is 150 mg, 300 mg or 600 mg twice daily<\/strong>depending on other medicines you are taking at the same time.&nbsp;Always take the&nbsp;doserecommended by your doctor.<br><\/p>\n\n\n\n<p><strong>People with kidney problems<\/strong><\/p>\n\n\n\n<p>If you have kidney problems, your doctor may need to change your&nbsp;dose&nbsp;.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Talk to your doctor<\/strong>&nbsp;if this applies to you.<\/li><\/ul>\n\n\n\n<p><strong>Adolescents and children from 2 years of age who weigh at least 10 kg<\/strong><\/p>\n\n\n\n<p>Your doctor will determine the correct&nbsp;dose&nbsp;of CELSENTRI based on weight and other medicines taken at the same time.<br><\/p>\n\n\n\n<p><strong>CELSENTRI can be taken independently of a meal.&nbsp;<\/strong>CELSENTRI should always be taken by mouth.<br><\/p>\n\n\n\n<p>CELSENTRI should be taken in combination with other medicines used to treat&nbsp;HIV&nbsp;.&nbsp;Read the package leaflet for these other medicines so that you know how to take them.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take or give too much CELSENTRI<\/h2>\n\n\n\n<p>If you have accidentally taken or given too much CELSENTRI:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Contact your doctor or nearest hospital immediately.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take or give CELSENTRI<\/h2>\n\n\n\n<p>If you (or your child) forget to take a&nbsp;dose&nbsp;of CELSENTRI, take or give the missed&nbsp;doseas soon as possible and then continue with the next&nbsp;dose&nbsp;at its usual time.<br><\/p>\n\n\n\n<p>If it is soon time for your next&nbsp;dose&nbsp;, do not take or give a&nbsp;dose&nbsp;you have forgotten.&nbsp;Wait until the usual time for the next&nbsp;dose&nbsp;.<br><\/p>\n\n\n\n<p><strong>Do not take or give a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you or your child stop taking CELSENTRI<\/h2>\n\n\n\n<p>Continue treatment with CELSENTRI until your doctor tells you to stop.<br><\/p>\n\n\n\n<p>It is important to take the medicine at the right time every day, because it ensures that&nbsp;HIV&nbsp;&#8211;&nbsp;infection,&nbsp;one does not increase in the body.&nbsp;Therefore, unless your doctor (or your child) tells you to stop treatment, it is important that you continue treatment with CELSENTRI correctly as described above.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;Talk to your doctor if you notice anything unusual about your or your child&#8217;s health.<br><\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;&#8211; contact a doctor immediately<\/strong><br><\/p>\n\n\n\n<p><strong>Severe allergic reactions or skin reactions<\/strong><\/p>\n\n\n\n<p>Some patients taking CELSENTRI have developed severe and life-threatening skin reactions and allergic reactions.&nbsp;These are rare and can affect up to 1 in 1,000 people taking CELSENTRI.<\/p>\n\n\n\n<p>If you get any of the following symptoms while taking CELSENTRI:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, lips or tongue<\/li><li>breathing difficulties<\/li><li>widespread skin rash<\/li><li>fever (high body temperature)<\/li><li>blisters and flaky skin, especially around the mouth, nose, eyes and genitals.<\/li><li><strong>Contact a doctor immediately<\/strong>&nbsp;if you get these symptoms.&nbsp;<strong>Stop taking CELSENTRI.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Liver problem<\/strong><\/p>\n\n\n\n<p>These are rare and may affect up to 1 in 1,000 people taking CELSENTRI.<\/p>\n\n\n\n<p>Characters include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>loss of appetite<\/li><li>nausea or vomiting<\/li><li>yellowing of the skin or eyes<\/li><li>skin rash or&nbsp;itching<\/li><li>feeling of enormous fatigue<\/li><li>abdominal pain or tenderness<\/li><li>dark-colored urine<\/li><li>drowsiness and confusion<\/li><li>fever (high body temperature).<\/li><li><strong>Contact a doctor immediately<\/strong>&nbsp;if you get these symptoms.&nbsp;<strong>Stop taking CELSENTRI.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These can occur in&nbsp;<strong>1 to 10 out of 100 people<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea, nausea, stomach pain,&nbsp;<em>flatulence<\/em>&nbsp;(&nbsp;<em>flatulence<\/em>&nbsp;)<\/li><li>loss of appetite<\/li><li>headache, sleep problems, depression<\/li><li>skin rash (&nbsp;<em>see also \u201cSevere allergic or skin reactions\u201d above in section 4)<\/em><\/li><li>lethargy or weakness,&nbsp;anemia&nbsp;(detected in blood samples)<\/li><li>increase in liver enzymes (detected in blood samples) which may be a sign of liver problems (&nbsp;<em>see also \u201cLiver problems\u201d above in section 4)<\/em>&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These can occur in up to&nbsp;<strong>1 in 100 people<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pneumonia<\/li><li>fungal infection of the esophagus<\/li><li>seizures<\/li><li>dizziness or fainting when standing up<\/li><li>kidney failure&nbsp;, egg white in the urine<\/li><li>elevated levels of a substance called CPK (detected in blood tests) which is a sign that muscles are inflamed or damaged.<br><\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>These can occur in&nbsp;<strong>up to 1 in 1,000 people<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>chest pain (caused by decreased blood flow to the heart)<\/li><li>reduced muscle size<\/li><li>certain types of cancer such as esophageal cancer or cancer of the bile ducts<\/li><li>decreased number of&nbsp;blood cells&nbsp;(detected in blood samples)<\/li><\/ul>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;are with&nbsp;combination therapy&nbsp;for&nbsp;HIV<\/strong><\/p>\n\n\n\n<p>People treated with combination therapy for&nbsp;HIV&nbsp;may experience other&nbsp;side effects&nbsp;.<br><\/p>\n\n\n\n<p><strong>Symptoms of&nbsp;infection&nbsp;and&nbsp;inflammation<\/strong><\/p>\n\n\n\n<p>People with advanced&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;(&nbsp;AIDS&nbsp;) have weak immune systems and are at greater risk of developing serious&nbsp;infection&nbsp;you (&nbsp;<em>opportunistic&nbsp;infection&nbsp;s<\/em>&nbsp;).&nbsp;When they start treatment, the immune system becomes stronger and the body begins to fight&nbsp;infection&nbsp;.<br><\/p>\n\n\n\n<p><strong>Symptoms of&nbsp;infection&nbsp;and&nbsp;inflammation<\/strong>&nbsp;can develop due to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>old hidden&nbsp;infection&nbsp;flares up again when the body starts fighting them<\/li><li>the immune system attacks healthy body tissue&nbsp;<em>(autoimmune diseases<\/em>&nbsp;).<br><\/li><\/ul>\n\n\n\n<p><strong>The symptoms of autoimmune diseases<\/strong>&nbsp;may develop several months after anti-&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;one began.&nbsp;The symptoms can be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>muscle weakness<\/li><li>weakness that begins in the hands and feet and spreads upwards towards the torso<\/li><li>palpitations or tremors<\/li><li>hyperactivity (great restlessness and excessive movements).<\/li><\/ul>\n\n\n\n<p>If you get any symptoms of&nbsp;infection&nbsp;or if you notice any of the above symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Tell your doctor immediately<\/strong>&nbsp;.&nbsp;Do not take other medicines for&nbsp;infection&nbsp;one without consulting your doctor.<br><\/li><\/ul>\n\n\n\n<p><strong>Joint pain, stiffness and skeletal problems<\/strong><br><\/p>\n\n\n\n<p>Some patients treated with combination therapy for&nbsp;HIV&nbsp;develop a condition called&nbsp;<em>osteonecrosis<\/em>&nbsp;.&nbsp;In this condition, parts of the bone tissue die due to reduced blood supply.<br><\/p>\n\n\n\n<p>It is not known how common this condition is.&nbsp;You may be at greater risk of getting it:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have been treated with combination therapy for a long time<\/li><li>if you are also taking anti-inflammatory medicines called&nbsp;corticosteroids&nbsp;s<\/li><li>if you drink alcohol<\/li><li>if your immune system is very weak<\/li><li>if you are overweight<\/li><\/ul>\n\n\n\n<p><strong>Signs to pay attention to:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stiffness in the joints<\/li><li>aches and pains (especially in the hips, knees or shoulders)<\/li><li>mobility impairment<\/li><\/ul>\n\n\n\n<p>If you notice any of these symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Tell your doctor.<\/strong><\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store CELSENTRI<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use CELSENTRI after the expiry date which is stated on the carton, blister or can label.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is maravirok.&nbsp;Each film-coated tablet contains 25 mg, 75 mg, 150 mg or 300 mg maraviroc.<br><\/li><li>Other ingredients are:<em><br>Tablet core:<\/em>&nbsp;microcrystalline cellulose, calcium hydrogen phosphate (anhydrous), sodium&nbsp;<em>starch glycolate<\/em>&nbsp;, magnesium stearate<br><em>Film coating:<\/em>&nbsp;poly (vinyl alcohol), titanium dioxide (E171), macrogol 3350, talc, soy lecithin, indigo carmine-aluminum lacquer (E132).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>CELSENTRI film-coated tablets are blue, imprinted with \u201cMVC 25\u201d, \u201cMVC 75\u201d, \u201cMVC 150\u201d or \u201cMVC 300\u201d.<br><\/p>\n\n\n\n<p>CELSENTRI 25 mg and 75 mg film-coated tablets are supplied in bottles of 120 tablets.<\/p>\n\n\n\n<p>CELSENTRI 150 mg and 300 mg film-coated tablets are supplied in bottles of 180 tablets or in blister packs of 30, 60, 90 film-coated tablets and multiple packs containing 180 (2 \u00d7 90) film-coated tablets.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed in all countries.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>ViiV Healthcare BV, Van Asch van Wijckstraat 55H, 3811 LP Amersfoort, The Netherlands.<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><br><\/p>\n\n\n\n<p>Pfizer Manufacturing Deutschland GmbH, Betreibsst\u0101tte Freiburg, Mooswaldallee 1, 79090 Freiburg, Germany<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>ViiV Healthcare srl \/ bvTel: +32 (0) 10 85 65 00<\/td><td><strong>Lithuania<\/strong>GlaxoSmithKline Lithuania UABTel: + 370 5 264 90 00info.lt@gsk.com<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>The GlaxoSmithKlein \u0415\u041e\u041e\u0414Tel .: + 359 2 953 10 34<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>ViiV Healthcare srl \/ bvBelgium \/ BelgiumTel: +32 (0) 10 85 65 00<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>GlaxoSmithKline sroTel: +420 222 001 111cz.info@gsk.com<\/td><td><strong>Hungary<\/strong>GlaxoSmithKline Kft.Tel .: +36 1 225 5300<\/td><\/tr><tr><td><strong>Denmark<\/strong>GlaxoSmithKline Pharma A \/ STel: + 45 36 35 91 00dk-info@gsk.com<\/td><td><strong>Malta<\/strong>GlaxoSmithKline (Malta) LimitedTel: +356 21 238131<\/td><\/tr><tr><td><strong>Germany<\/strong>ViiV Healthcare GmbHTel .: + 49 (0) 89 203 0038-10viiv.med.info@viivhealthcare.com<\/td><td><strong>The Netherlands<\/strong>ViiV Healthcare BVTel: + 31 (0) 33 2081199<\/td><\/tr><tr><td><strong>Eesti<\/strong>GlaxoSmithKline Eesti O\u00dcTel: + 372 6676 900estonia@gsk.com<\/td><td><strong>Norway<\/strong>GlaxoSmithKline ASTel: + 47 22 70 20 00<br><\/td><\/tr><tr><td><strong>Greece<\/strong>GlaxoSmithKline A\u03bf\u03bd\u03bf\u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03b7 AEBE:\u0397\u03bb: + 30 210 68 82 100<\/td><td><strong>Austria<\/strong>GlaxoSmithKline Pharma GmbHTel: + 43 (0) 1 97075 0at.info@gsk.com<\/td><\/tr><tr><td><strong>Spain<\/strong>Laboratories ViiV Healthcare, SLTel: +34 900 923 501es-ci@viivhealthcare.com&nbsp;<\/td><td><strong>Poland<\/strong>GSK Services Sp.&nbsp;z ooTel .: + 48 (0) 22 576 9000<\/td><\/tr><tr><td><strong>France<\/strong>ViiV Healthcare SASTel .: + 33 (0) 1 39 17 6969Infomed@viivhealthcare.com<\/td><td><strong>Portugal<\/strong>VIIVHIV HEALTHCARE, UNIPESSOAL, LDA.Tel: + 351 21 094 08 01viiv.fi.pt@viivhealthcare.com<\/td><\/tr><tr><td><strong>Croatia<\/strong>GlaxoSmithKline dooTel: + 385 1 6051 999<\/td><td><strong>Romania<\/strong>GlaxoSmithKline (GSK) SRLTel: + 4021 3028 208<\/td><\/tr><tr><td><strong>Ireland<\/strong>GlaxoSmithKline (Ireland) LimitedTel: + 353 (0) 1 4955000<\/td><td><strong>Slovenia<\/strong>GlaxoSmithKline dooTel: + 386 (0) 1 280 25 00medical.x.si@gsk.com<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: + 354 535 7000<\/td><td><strong>Slovak Republic<\/strong>GlaxoSmithKline Slovakia sroTel: + 421 (0) 2 48 26 11 11recepcia.sk@gsk.com<\/td><\/tr><tr><td><strong>Italy<\/strong>ViiV Healthcare SrlTel: +39 (0) 45 9212611<\/td><td><strong>Finland \/ Finland<\/strong>GlaxoSmithKline OyPuh \/ Tel: + 358 (0) 10 30 30 30Finland.tuoteinfo@gsk.com<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>GlaxoSmithKline Cyprus Ltd:\u0397\u03bb: + 357 22 39 70 00gskcyprus@gsk.com<\/td><td><\/td><\/tr><tr><td><strong>Latvia<\/strong>GlaxoSmithKline Latvia SIATel: + 371 67312687lv-epasts@gsk.com<\/td><td><strong>United Kingdom<\/strong>ViiV Healthcare UK LtdTel: + 44 (0) 800 221441customercontactuk@gsk.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>CELSENTRI contains a substance called maravirok. Maraviroc belongs to a class of drugs called CCR5 antagonist you . CELSENTRI works by blocking a receptor called CCR5, which HIV uses to enter and infect your blood cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7510,7512,7513,7505,7507,7508,7509,2212,2210,7511,7506],"class_list":["post-6639","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-celsentri","tag-celsentri-side-effects","tag-celsentri-tablet","tag-maravirok","tag-maravirok-side-effects","tag-maravirok-tablet","tag-maravirok-uses","tag-medicine","tag-tablet","tag-what-is-celsentri","tag-what-is-maravirok"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6639"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6639\/revisions"}],"predecessor-version":[{"id":11535,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6639\/revisions\/11535"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6639"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}