Celecoxib Sandoz contains sodium<\/strong><\/p>\n\n\n\nThis medicine contains less than 1 mmol (23 mg) sodium per capsule, ie essentially ‘sodium-free’.
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How to take Celecoxib Sandoz<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.
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As the risk of heart side effects may increase with high doses and long-term treatment, it is important that you take the lowest dose to keep your pain under control and not use this medicine for longer than you need to keep your symptoms under control.<\/p>\n\n\n\n
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Contact your doctor if you do not experience any improvement after two weeks of treatment.
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The recommended dose is:<\/strong>
<\/p>\n\n\n\nIn degenerative joint disease<\/strong> ( osteoarthritis ), the recommended dose is 200 mg daily, which the doctor may increase to a maximum of 400 mg if necessary.<\/p>\n\n\n\nUsual dose is:<\/p>\n\n\n\n
- one 200 mg capsule once a day or<\/li>
- one capsule of 100 mg twice a day.<\/li><\/ul>\n\n\n\n
In inflammatory rheumatic arthritis<\/strong> ( rheumatoid arthritis ), the recommended dose is 200 mg daily, which the doctor may increase to a maximum of 400 mg if necessary.<\/p>\n\n\n\nUsual dose is:<\/p>\n\n\n\n
- one capsule of 100 mg twice a day.<\/li><\/ul>\n\n\n\n
In certain types of inflammation between the vertebrae<\/strong> ( pelvic spondylitis ), the recommended dose is 200 mg daily, which the doctor may increase to a maximum of 400 mg if necessary.<\/p>\n\n\n\nUsual dose is:<\/p>\n\n\n\n
- one 200 mg capsule once a day or<\/li>
- one capsule of 100 mg twice a day.<\/li><\/ul>\n\n\n\n
Do not take more than 400 mg daily<\/strong> in any treatment indication.
<\/p>\n\n\n\nOlder<\/strong><\/p>\n\n\n\nIf you are over 65 years of age, and especially if you weigh less than 50 kg, your doctor may want to check you more closely.
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Kidney or liver problems<\/strong><\/p>\n\n\n\nIf you have kidney or liver problems, tell your doctor as you may need to take a lower dose .
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Use<\/strong><\/p>\n\n\n\nCelecoxib Sandoz is for oral use (should be swallowed).<\/p>\n\n\n\n
Take the capsule (s):<\/p>\n\n\n\n
- swallow them whole with a glass of water<\/li>
- preferably at the same time each day<\/li>
- with or without food.<\/li><\/ul>\n\n\n\n
If you have difficulty swallowing capsules: All the contents of the capsule can be sprinkled on a teaspoon of semi-solid food (eg cold or room temperature apple puree, rice gruel, yoghurt or mashed banana) and swallowed immediately with a glass of water.
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Open the capsule by holding it upright so that the granules collect at the bottom. Then gently squeeze the upper part and remove it with a twisting motion. Be careful not to spill any of the contents. Granules must not be chewed or crushed.<\/strong><\/p>\n\n\n\nIf you forget to take Celecoxib Sandoz<\/h2>\n\n\n\n
It is important that you take your medication every day. If you forget to take one or more doses , take them as soon as you remember and then continue with the usual dose .<\/p>\n\n\n\n
Do not take a double dose to make up for a forgotten dose .<\/p>\n\n\n\n
If you stop taking Celecoxib Sandoz<\/h2>\n\n\n\n
Always consult a doctor before stopping this medicine. Even if you are feeling well, your doctor may decide that you need to continue taking this medicine.
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If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects , although not everybody gets them.
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The adverse reactions listed below have been observed in patients with arthritis taking celecoxib. Adverse reactions marked with an asterisk (*) are listed below with the higher frequency seen in patients taking celecoxib to prevent colon polyps. Patients in these studies took celecoxib in high doses and for a long time.<\/strong>
<\/p>\n\n\n\nIf any of the following occur, stop taking Celecoxib Sandoz and contact <\/strong>your <\/strong>doctor <\/strong>immediately <\/strong>:<\/strong><\/p>\n\n\n\n- an allergic reaction such as a rash, swelling of the face, wheezing or difficulty breathing<\/li>
- heart problems such as chest pain<\/li>
- severe stomach pain or signs of bleeding in the stomach or intestines, e.g. black or blood-stained stools or vomiting with blood<\/li>
- a skin reaction such as rash, blistering or flaking<\/li>
- liver failure (symptoms may include nausea, diarrhea, jaundice (your skin or whites of the eyes look yellowish)).<\/li><\/ul>\n\n\n\n
Possible side effects:<\/strong>
<\/p>\n\n\n\nVery common<\/strong> (may affect more than 1 user in 10)<\/p>\n\n\n\n- high blood pressure , including worsening of already high blood pressure *<\/li><\/ul>\n\n\n\n
Common<\/strong> (may affect up to 1 in 10 people)<\/p>\n\n\n\n- sinusitis ( sinusitis )<\/li>
- upper respiratory tract infection<\/li>
- urinary tract infection<\/li>
- deterioration of existing allergy s<\/li>
- difficulty sleeping, dizziness<\/li>
- muscle stiffness<\/li>
- headache<\/li>
- myocardial infarction*<\/li>
- cough<\/li>
- breathing difficulties *<\/li>
- sore throat<\/li>
- runny nose or nasal congestion, sneezing<\/li>
- magont<\/li>
- diarrhea<\/li>
- indigestion<\/li>
- weather voltage<\/li>
- nausea<\/li>
- vomiting *<\/li>
- difficulty swallowing *<\/li>
- rash, itching<\/li>
- joint pain<\/li>
- fluid accumulation in the body that can cause swelling in the ankles, legs and \/ or hands<\/li>
- flu-like symptoms<\/li>
- accident<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n- decreased number of red blood cells that can make the skin pale and you become weak or short of breath<\/li>
- increased amount of potassium in the blood which can lead to muscle weakness, muscle twitching or irregular heartbeat<\/li>
- anxiety, depression, fatigue<\/li>
- stroke*<\/li>
- tingling or numbness ( paresthesia ), drowsiness<\/li>
- blurred vision, eye inflammation ( conjunctivitis )<\/li>
- earring, hearing loss *<\/li>
- heart failure<\/li>
- rapid heartbeat or palpitations<\/li>
- difficulty breathing ( bronchospasm )<\/li>
- constipation, belching, inflammation of the stomach, worsening inflammation of the stomach or intestines<\/li>
- soreness in the mouth, cold sores<\/li>
- changes in liver values, increase in liver enzymes in the blood, e.g. AST and ALAT<\/li>
- raised, itchy rash (hives)<\/li>
- discoloration of the skin (bruises)<\/li>
- leg cramps<\/li>
- changes in renal values \u200b\u200bduring blood tests: increase in creatinine and urea nitrogen in the blood<\/li>
- facial swelling<\/li>
- chest pain (general pain unrelated to the heart)<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n- reduced number of white blood cells , which help protect the body against infection ( leukopenia )<\/li>
- decreased platelet count , which increases the risk of bleeding or bruising<\/li>
- confusion<\/li>
- hallucinations<\/li>
- difficulty controlling movements ( ataxia )<\/li>
- taste changes<\/li>
- eye bleeding<\/li>
- irregular heartbeats<\/li>
- blood clot in the blood vessels of the lungs. Symptoms may include sudden shortness of breath, sharp pain when breathing or collapse<\/li>
- acute reaction that can lead to pneumonia<\/li>
- hemorrhage<\/li>
- bleeding in the stomach or intestines (may lead to blood in the stool or bloody vomiting), intestinal inflammation<\/li>
- ulcer (bleeding) in the esophagus, stomach or intestines or ruptured intestine (may cause abdominal pain, fever, nausea, vomiting, intestinal obstruction)<\/li>
- inflammation of the esophagus that can cause difficulty swallowing ( esophagitis )<\/li>
- dark or black stools<\/li>
- inflammation of the pancreas that causes severe pain in the abdomen and back<\/li>
- serious liver inflammation ( hepatitis ). Symptoms may include nausea, diarrhea, jaundice (yellowing of the skin or eyes), dark urine, pale stools, increased tendency to bleed, itching or chills<\/li>
- swelling of the face, lips, mouth, tongue or throat or difficulty swallowing<\/li>
- hair loss<\/li>
- increased photosensitivity<\/li>
- acute renal failure<\/li>
- decreased amount of sodium in the blood which can cause fatigue, confusion, muscle cramps, seizures and coma<\/li>
- menstrual disorders<\/li><\/ul>\n\n\n\n
Very rare<\/strong> (may affect up to 1 in 10,000 people)<\/p>\n\n\n\n- decreased number of red and white blood cells and platelets (may lead to fatigue, increased tendency to get bruises, frequent nosebleeds and increased risk of infection)<\/li>
- severe allergic reactions including possible fatal anaphylactic shock<\/li>
- bleeding in the brain (including death)<\/li>
- inflammation of the membrane around the brain and spinal cord that is not caused by infection (aseptic meningitis )<\/li>
- seizures or worsening of epilepsy (possibly increased number of seizures and \/ or increased severity)<\/li>
- lost sense of taste<\/li>
- lost sense of smell<\/li>
- blockage of an artery or vein in the eye leading to complete or partial loss of vision<\/li>
- inflammation in a blood vessel that can lead to fever, pain or dark purple spots on the skin<\/li>
- hepatic failure, liver damage, severe hepatitis ( fulminant hepatitis ) (sometimes fatal or requiring liver transplant). Symptoms may include nausea, diarrhea, jaundice (yellowing of the skin or eyes), dark urine, pale stools, increased tendency to bleed, itching or chillsIn cases where the time to onset of symptoms was reported, most severe liver reactions were seen within one month of starting treatment.<\/li>
- liver problems such as cholestasis and cholestatic hepatitis , which may be accompanied by symptoms such as discolored stools, nausea and yellow skin or yellow eyes<\/li>
- severe skin side effects such as Stevens-Johnson syndrome , exfoliative dermatitisand toxic epidermal necrolysis (which may cause rash, blistering or flaking of the skin and acute generalized exanthematous pustulosis (symptoms which cause the skin to become red with swollen areas covered with many small blisters)<\/li>
- a delayed allergic reaction with possible symptoms such as rash, swelling of the face, fever, swollen glands and abnormal test results, e.g. in liver and blood cell tests ( eosinophilia , a type of increased white blood cell count ). This reaction is called drug-induced rash with eosinophilia and systemic symptoms (DRESS) or hypersensitivity syndrome.<\/li>
- muscle inflammation with pain and weakness<\/li>
- inflammation of the kidneys and other kidney problems (eg nephrotic syndromeand minimal change disease, which may be accompanied by symptoms such as fluid in the body ( edema ), frothy urine, fatigue and decreased appetite)<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in unknown number of users)<\/p>\n\n\n\n