{"id":6596,"date":"2021-01-10T14:58:05","date_gmt":"2021-01-10T14:58:05","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6596"},"modified":"2023-02-27T08:02:40","modified_gmt":"2023-02-27T08:02:40","slug":"celebra","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/celebra\/","title":{"rendered":"Celebra &#8211; Celecoxib Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Celebra 200 mg celecoxib Hard Capsules<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. what Is Celebra, And What Celebra Used For?<\/h2>\n\n\n\n<p>Celebra is used in adults for symptom relief in treating\u00a0<strong>chronic\u00a0rheumatoid arthritis,\u00a0osteoarthritis,<\/strong>\u00a0and\u00a0<strong>pelvic pondylitis<\/strong>\u00a0(Mb. Bechterews, a rheumatic back disease).<\/p>\n\n\n\n<p>Celebra belongs to a group of medicines called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0) and, more specifically, to the subgroup inhibitors of\u00a0cyclooxygenase-2\u00a0(\u00a0COX-2).<\/p>\n\n\n\n<p>Your body produces\u00a0prostaglandins\u00a0that can cause pain and\u00a0inflammation; in conditions such as\u00a0rheumatoid arthritis\u00a0and\u00a0osteoarthritis, it produces more of them.\u00a0Celebra works by reducing the production of\u00a0prostaglandins\u00a0and thus reducing pain and\u00a0inflammation.<\/p>\n\n\n\n<p>You can expect the medicine to start working within a few hours of taking the first\u00a0dose, but it may take several days before it takes full effect.<\/p>\n\n\n\n<p>Celecoxib contained in Celebra may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Celebra?<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Celebra:<\/h2>\n\n\n\n<p>You have been prescribed celebra medicine by your doctor.\u00a0The following information will help you get the best results from your treatment.\u00a0If you have any further questions, ask your doctor or pharmacist.<\/p>\n\n\n\n<p><strong>Do not take Celebra<\/strong>:<\/p>\n\n\n\n<p>Tell your doctor if any of the following apply to you, as patients with these conditions should not take Celebra.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to celecoxib or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have had an\u00a0allergic reaction\u00a0to a group of medicines called &#8216;sulfonamides&#8217; (e.g., some\u00a0antibiotics\u00a0used to treat\u00a0infections\u00a0)<\/li><li>If you\u00a0<strong>currently<\/strong>\u00a0have ulcers or bleeding in the stomach\/intestines<\/li><li>If you have had\u00a0asthma, nasal polyps, severe nasal congestion, or an\u00a0allergic reaction\u00a0such as itchy kin rash, swelling of the face, lips, tongue, or throat, difficulty breathing or wheezing after taking\u00a0acetylsalicylic acid\u00a0or any other anti-inflammatory and analgesic medicine (\u00a0NSAID\u00a0)<\/li><li>If you are pregnant.\u00a0If you are likely to become pregnant during treatment, you should discuss appropriate contraceptive methods with your doctor<\/li><li>If you are breast-feeding<\/li><li>If you have severe liver disease<\/li><li>If you have severe kidney disease<\/li><li>If you have an\u00a0inflammatory\u00a0bowel disease, such as ulcerative colitis or\u00a0Crohn&#8217;s disease<\/li><li>If you have\u00a0heart failure\u00a0or known ischemic heart disease or disease of the blood vessels of the brain, e.g.,\u00a0if you have had a heart attack,\u00a0stroke, temporary decrease in blood flow to the brain (also known as &#8220;mini-stroke&#8221;), angina, or narrowing of the blood vessels to the heart or brain<\/li><li>If you have or have had problems with blood circulation (\u00a0peripheral\u00a0vascular disease) or if you have had surgery on the blood vessels in your legs<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions:<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Celebra:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have\u00a0<strong>previously<\/strong>\u00a0had ulcers or bleeding in the stomach or intestines(\u00a0<strong>Do not take Celebra<\/strong>\u00a0if you\u00a0<strong>currently<\/strong>\u00a0have ulcers or bleeding in the stomach or intestines)<\/li><li>If you are taking\u00a0acetylsalicylic acid\u00a0(even at low\u00a0doses\u00a0to protect your heart)<\/li><li>If you are taking medicines that reduce the formation of\u00a0platelets<\/li><li>If you are taking medicines to reduce blood clots (e.g., warfarin \/ warfarin-like\u00a0anticoagulants\u00a0or new oral blood thinners, e.g., apixaban)<\/li><li>If you are taking medicines called\u00a0corticosteroids\u00a0(e.g., prednisone)<\/li><li>If you take Celebra while taking other\u00a0NSAIDs\u00a0(besides\u00a0acetylsalicylic acid\u00a0), such as\u00a0ibuprofen\u00a0or\u00a0diclofenac.\u00a0Concomitant use of these drugs should be avoided<\/li><li>If you smoke, have\u00a0diabetes, high\u00a0blood pressure,\u00a0or high cholesterol<\/li><li>If your heart, liver, or kidneys are not working correctly, your doctor may want to check you regularly<\/li><li>If you have fluid retention in your body (such as swollen ankles and feet)<\/li><li>If you are dehydrated, e.g.,\u00a0due to vomiting, diarrhea, or if you are taking\u00a0diuretics(to treat fluid retention in the body)<\/li><li>If you have had a severe\u00a0allergic reaction\u00a0or a severe skin reaction to any medicine<\/li><li>If you have an\u00a0infection\u00a0or suspect you have an\u00a0infection, as Celebra may mask fever or other signs of\u00a0infection\u00a0and\u00a0inflammation<\/li><li>If you are over 65, your doctor will check you regularly<\/li><li>Intake of alcohol and\u00a0NSAIDs\u00a0may increase the risk of gastrointestinal upset<\/li><\/ul>\n\n\n\n<p>Like other\u00a0NSAIDs\u00a0(such as\u00a0ibuprofen\u00a0or\u00a0diclofenac\u00a0), this medicine may cause high\u00a0blood pressure, so your doctor may ask you to check your\u00a0blood pressure\u00a0regularly. Some cases of severe hepatic reaction have been reported following the use of celecoxib, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe hepatitis<\/li><li>Liver damage<\/li><li>Liver failure (some cases fatal or requiring liver transplantation)<\/li><\/ul>\n\n\n\n<p><strong>In cases where the time of onset of symptoms was reported, most severe liver reactions were seen within one month of starting treatment.<\/strong> Celebra can make it harder to get pregnant.\u00a0You should tell your doctor if you are planning to become pregnant or have difficulty getting pregnant (see the section on Pregnancy and breast-feeding).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Celebra:<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dextromethorphan (used to treat cough)<\/li><li>ACE inhibitors,\u00a0angiotensin\u00a0II inhibitors,\u00a0beta-blockers,\u00a0and diuretics (used for high\u00a0blood pressure\u00a0and\u00a0heart failure\u00a0)<\/li><li>Fluconazole\u00a0and rifampicin (used to treat fungal and bacterial infections)<\/li><li>Warfarin\u00a0or other warfarin-like medicines (blood thinners that reduce blood clotting), including newer medicines like apixaban<\/li><li>Lithium (used to treat certain types of depression)<\/li><li>Other medicines for depression, sleep disorders, high\u00a0blood pressure\u00a0or irregular heartbeat<\/li><li>Neuroleptics\u00a0(used to treat certain mental illnesses)<\/li><li>Methotrexate (used to treat rheumatic joint disease,\u00a0psoriasis,\u00a0and\u00a0leukemia\u00a0)<\/li><li>Carbamazepine (used to treat epilepsy\/seizures and certain forms of pain or depression)<\/li><li>Barbiturates\u00a0(used to treat epilepsy\/seizures and certain sleep disorders)<\/li><li>Ciclosporin and tacrolimus (used to suppress the immune system, e.g., after transplants)<\/li><\/ul>\n\n\n\n<p>Celebra can be taken with a low&nbsp;dose&nbsp;of&nbsp;acetylsalicylic acid&nbsp;(75 mg or less per day).&nbsp;Ask your doctor for advice before taking these medicines at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility:<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Pregnancy<\/span><\/strong><\/em><\/p>\n\n\n\n<p>Celebra must not be used by pregnant women or may become pregnant during treatment (i.e., women of\u00a0childbearing potential\u00a0not using adequate contraception).\u00a0If you become pregnant during treatment with Celebra, you should stop and contact your doctor for other treatment.<\/p>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Breast-feeding<\/span><\/strong><\/em><\/p>\n\n\n\n<p>Celebra must not be used during breast-feeding.<\/p>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Fertility<\/span><\/strong><\/em><\/p>\n\n\n\n<p>NSAIDs,\u00a0including Celebra can make it harder to get pregnant.\u00a0Tell your doctor if you plan to become pregnant or have problems getting pregnant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines:<\/h2>\n\n\n\n<p>You should know how to react to Celebra before driving or using machines.\u00a0If you feel dizzy or drowsy after taking Celebra, do not drive or use machines until these effects have subsided.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects or\u00a0side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Celebra Contains Lactose:<\/h2>\n\n\n\n<p>Celebra contains\u00a0<strong>lactose<\/strong>\u00a0(a sugar).\u00a0If your doctor has told you that you are intolerant to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Celebra?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine exactly as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0If you have the impression that the effect of Celebra is too strong or too weak, talk to your doctor or pharmacist.<\/li><li>Your doctor will tell you which\u00a0dose\u00a0to take.\u00a0As the risk of heart side effects may increase with high\u00a0doses\u00a0and long-term treatment, you mustn&#8217;t take a higher\u00a0dose\u00a0or use Celebra for longer than you need to control your symptoms.<\/li><li>Method of administration:<ul><li>Celebra is for\u00a0oral\u00a0use (should be swallowed).\u00a0Your\u00a0dose\u00a0can be taken at any time, with or without food, but try to take each dose simultaneously.<\/li><li>If you have difficulty swallowing capsules, all capsule contents can be sprinkled on a teaspoon of semi-solid food (e.g., cold or room-warm apple puree, rice gruel, yogurt or mashed banana) and swallowed immediately with about 240 ml of water. <\/li><li>Hold the capsule upright so the\u00a0granules\u00a0collect at the bottom.\u00a0Then gently squeeze the upper part and remove it with a twisting motion.\u00a0Be careful not to spill any of the contents.\u00a0Granules\u00a0must not be chewed or crushed.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Contact your doctor if you do not experience any improvement after two weeks of treatment.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>In\u00a0osteoarthritis<\/strong>, the recommended\u00a0dose is\u00a0200 mg daily, which can be increased to a maximum of 400 mg if your doctor deems it necessary. The usual\u00a0dose\u00a0is:<ul><li>One 200 mg capsule once a day, or<\/li><li>One capsule of 100 mg twice a day.<\/li><\/ul><\/li><li><strong>In\u00a0chronic\u00a0rheumatoid arthritis<\/strong>, the recommended\u00a0dose is\u00a0200 mg daily, which can be increased to a maximum of 400 mg if your doctor deems it necessary.<\/li><li>The usual\u00a0dose\u00a0is:<ul><li>One capsule of 100 mg twice a day.<\/li><\/ul><\/li><li><strong>In the case of\u00a0pelvic pondylitis<\/strong>\u00a0, the usual\u00a0dose is\u00a0200 mg daily, which can be increased to a maximum of 400 mg if your doctor deems it necessary.<ul><li>The usual\u00a0dose\u00a0is:<ul><li>One 200 mg capsule once a day, or <\/li><li>One capsule of 100 mg twice a day.<\/li><\/ul><\/li><\/ul><\/li><li><strong>Kidney or liver failure:<\/strong>\u00a0If you have kidney or liver failure, tell your doctor, as you may need to take a lower\u00a0dose.<\/li><li><strong>Elderly people, especially those weighing less than 50 kg:<\/strong>\u00a0If you are over 65, and especially if you weigh less than 50 kg, your doctor may want to check you more closely.<\/li><li>You should not take more than 400 mg daily.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use In Children:<\/h2>\n\n\n\n<p>Celebra is for adults only and should not be used in children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Celebra:<\/h2>\n\n\n\n<p>If you forget to take your&nbsp;dose, take it as soon as you remember.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Taking Celebra:<\/h2>\n\n\n\n<p>If you suddenly stop taking Celebra, your symptoms may get worse.\u00a0Do not stop taking Celebra unless your doctor tells you to.\u00a0Your doctor may ask you to reduce your\u00a0dose\u00a0for a few days before stopping treatment altogether. Ask your doctor or pharmacist if you have any further questions about using this product.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Celebra Side Effects:<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines,\u00a0although not everybody gets them. <strong>The side effects\u00a0listed below have been observed in patients with\u00a0osteoarthritis who have used Celebra.\u00a0Side effects\u00a0marked with an asterisk (*) are indicated with the higher frequency seen in patients who used Celebra to prevent colon polyps.\u00a0These patients took Celebra in high\u00a0doses\u00a0and for a long time.<\/strong><\/p>\n\n\n\n<p><strong>If any of the following occur, stop taking Celebra and contact a doctor immediately:<\/strong><\/p>\n\n\n\n<p><strong>If you experience:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An\u00a0allergic reaction\u00a0such as skin rash, swelling of the face, wheezing, or difficulty breathing<\/li><li>Heart problems such as chest pain<\/li><li>Severe stomach pain or signs of bleeding in the stomach or intestines, e.g.,\u00a0black or bloodstained stools or vomiting with blood in<\/li><li>A skin reaction such as rash, blistering or flaking<\/li><li>Liver failure (symptoms may include nausea, diarrhea, jaundice (your skin or whites of the eyes look yellowish))<\/li><\/ul>\n\n\n\n<p><strong>Very common: may affect more than 1 user in 10:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High\u00a0blood pressure,\u00a0including an increase in already high blood pressure *<\/li><\/ul>\n\n\n\n<p><strong>Common: may affect up to 1 user in 10:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Myocardial infarction*<\/li><li>Accumulation of fluid in the body that can cause swelling in the ankles, legs, or hands<\/li><li>Urinary tract infection<\/li><li>Difficulty breathing *, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sinusitis\/\">sinusitis<\/a>, nasal congestion or runny nose, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">sore throat<\/a>, cough, cold,\u00a0flu-like symptoms<\/li><li>Dizziness, difficulty sleeping<\/li><li>Vomiting *, stomach pain, diarrhea, digestive problems<\/li><li>Flatulence<\/li><li>Rash,\u00a0itching<\/li><li>Muscle tension<\/li><li>Difficulty swallowing *<\/li><li>Headache<\/li><li>Nausea<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a><\/li><li>Worsening of existing\u00a0allergies\u00a0you<\/li><li>Damage in the event of an accident<\/li><\/ul>\n\n\n\n<p><strong>Uncommon: may affect up to 1 user in 100:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stroke*<\/li><li>Heart failure\u00a0, palpitations, rapid heartbeat<\/li><li>Changes in liver values \u200b\u200bduring blood tests<\/li><li>Changes in kidney values \u200b\u200bduring blood tests<\/li><li>Anemia\u00a0(decreased number of\u00a0red blood cells, which can cause weakness and shortness of breath)<\/li><li>Anxiety, depression, fatigue, drowsiness, ant crawling.<\/li><li>Increased potassium in the blood (may cause nausea, fatigue, muscle weakness, or palpitations)<\/li><li>Impaired vision or blurred vision,\u00a0tinnitus, soreness in the mouth, cold sores, hearing loss *<\/li><li>Constipation, belching, gastritis (indigestion, stomach pain, or vomiting), worsening\u00a0inflammation\u00a0of the stomach or intestines<\/li><li>Leg cramps<\/li><li>Elevated, itchy rash (\u00a0hives\u00a0)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/eye-inflammation-in-children\/\">Eye inflammation<\/a><\/li><li>Breathing difficulties<\/li><li>Discolored skin (bruises)<\/li><li>Chest pain (general pain not related to the heart)<\/li><li>Facial swelling<\/li><\/ul>\n\n\n\n<p><strong>Rare: may affect up to 1 user in 1,000:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ulcers (bleeding) in the stomach, esophagus, and intestine, ruptured intestine (may cause abdominal pain, fever, nausea, vomiting, intestinal obstruction), dark or black stools,\u00a0inflammation\u00a0of the pancreas (may cause abdominal pain),\u00a0inflammation\u00a0of the esophagus (\u00a0esophagitis\u00a0)<\/li><li>Decreased amount of sodium in the blood (a condition known as\u00a0hyponatremia\u00a0)<\/li><li>Reduced\u00a0white blood cell count\u00a0(which helps protect the body against\u00a0infection\u00a0) and\u00a0platelets\u00a0(increased risk of bleeding or bruising)<\/li><li>Difficulty coordinating muscle movements<\/li><li>Confusion, taste changes<\/li><li>Increased light sensitivity<\/li><li>Hair loss<\/li><li>Hallucinations<\/li><li>Bleeding in the eye<\/li><li>The acute\u00a0reaction that can lead to\u00a0pneumonia<\/li><li>Irregular heartbeats<\/li><li>Pastures<\/li><li>Blood clots in the blood vessels of the lungs.\u00a0Symptoms may include sudden shortness of breath, sharp pain when breathing, or collapse.<\/li><li>Bleeding in the stomach or intestines (may cause bloody stools or vomiting), intestinal inflammation.<\/li><li>Serious liver inflammation (\u00a0hepatitis\u00a0).\u00a0Symptoms may include nausea, diarrhea, jaundice (yellowing of the skin or eyes), dark urine, pale stools, increased tendency to bleed,\u00a0itching,\u00a0or chills.<\/li><li>Acute\u00a0renal failure<\/li><li>Menstrual disorders<\/li><li>Swelling of the face, lips, mouth, tongue or throat, wheezing or difficulty swallowing<\/li><\/ul>\n\n\n\n<p><strong>Very rare: may affect up to 1 user in 10,000:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe skin reactions (including anaphylactic\u00a0shock, which may be life-threatening)<\/li><li>Severe skin conditions such as\u00a0Stevens-Johnson syndrome, exfoliative\u00a0dermatitis and\u00a0toxic epidermal necrolysis\u00a0(which may cause rash, blistering, or flaking of the skin) and\u00a0acute\u00a0rash-like generalized\u00a0pustulosis\u00a0(red, swollen area with many small blisters)<\/li><li>A delayed\u00a0allergic reaction\u00a0with possible symptoms such as rash, swelling of the face, fever, swollen\u00a0glands,\u00a0and abnormal test results (eg, liver and blood cell tests (\u00a0eosinophilia, a increased\u00a0white blood cell count\u00a0))<\/li><li>Cerebral hemorrhage, which can be life-threatening<\/li><li>Meningitis\u00a0(\u00a0inflammation\u00a0of the meninges)<\/li><li>Liver failure, liver damage, and severe liver inflammation (\u00a0fulminant\u00a0hepatitis\u00a0) (some with fatal outcome or requiring liver transplant).\u00a0Symptoms may include nausea, diarrhea, jaundice (yellowing of the skin or eyes), dark urine, pale stools, increased tendency to bleed,\u00a0itching,\u00a0or chills.<\/li><li>Liver problems (eg, cholestasis and cholestatic\u00a0hepatitis, which may be accompanied by symptoms such as discolored stools, nausea, and yellow skin or yellow eyes)<\/li><li>Kidney inflammation and other kidney problems (eg,\u00a0nephrotic syndrome\u00a0and minimal change disease that may be accompanied by symptoms such as\u00a0fluid retention\u00a0(\u00a0edema\u00a0), frothy urine, fatigue, and loss of appetite)<\/li><li>Impaired\u00a0epilepsy\u00a0(possibly increased number of seizures or increased severity)<\/li><li>Partial or complete vision loss caused by blockage of a blood vessel in the eye<\/li><li>Inflammation\u00a0of the blood vessels (may cause fever, aches, dark purple spots on the skin)<\/li><li>Deficiency of all blood cells (may cause fatigue, increase the tendency to get bruises, frequent nosebleeds, and increased risk of infection)<\/li><li>Muscle aches and weakness<\/li><li>Impaired sense of smell<\/li><li>Loss of taste<\/li><\/ul>\n\n\n\n<p><strong>No known frequency: (occurrence cannot be calculated from available data):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased&nbsp;fertility&nbsp;in women, which is usually transient at the end of treatment<\/li><\/ul>\n\n\n\n<p><strong>In\u00a0addition, in clinical trials\u00a0of conditions other than\u00a0osteoarthritis\u00a0or joint problems, where Celebra was given in a\u00a0dose\u00a0of 400 mg daily for up to 3 years, the following\u00a0side effects have\u00a0been observed<\/strong>:<\/p>\n\n\n\n<p><strong>Common: may affect up to 1 user in 10:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Angina (chest pain)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/ibs-sensitive-bowel\/\">Irritable bowel syndrome<\/a> (may include abdominal pain, diarrhea, digestive problems, flatulence)<\/li><li>Kidney stones&nbsp;(may cause pain in the abdomen or back, blood in the urine), urinary incontinence<\/li><li>Weight gain<\/li><\/ul>\n\n\n\n<p><strong>Uncommon: may affect up to 1 in 100 users:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Deep\u00a0vein thrombosis\u00a0(blood clot, usually in the legs, which can cause pain, swelling or\u00a0redness\u00a0in the calf or difficulty breathing)<\/li><li>Stomach infection (which can cause irritation and ulcers in the stomach and intestines)<\/li><li>Fracture\u00a0of the forearm \/ lower leg,\u00a0shingles, skin infection,\u00a0eczema\u00a0(dry, itchy rash),\u00a0pneumonia\u00a0(cough, fever, difficulty breathing)<\/li><li>Visual impairment caused by small spots in the\u00a0visual field<\/li><li>Dizziness caused by problems in the inner ear, tender, inflamed or bleeding gums, cold sores, need to urinate frequently at night, bleeding from\u00a0hemorrhoids, anxious intestine, lumps of fat in the subcutaneous tissue,\u00a0ganglion\u00a0(benign swelling of the wrist and ankle tendons)<\/li><li>Speech problems, abdominal bleeding, breast tenderness, increased sodium in the blood.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This includes any possible side effects not listed in this leaflet.\u00a0You can also report side effects directly to the Medical Products Agency,\u00a0www.lakemedelsverket.se.\u00a0By reporting side effects, you can help increase drug safety information.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Celebra?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the blister and carton expiry date.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not store above 30 \u00b0 C.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is celecoxib.<\/li><li>1 capsule contains 100 mg or 200 mg celecoxib.<\/li><li>Other ingredients are:<ul><li>Lactose monohydrate<\/li><li>Sodium lauryl sulfate<\/li><li>Povidone<\/li><li>Croscarmellose sodium<\/li><li>Magnesium stearate<\/li><li>The capsule shell contains gelatin, titanium dioxide E171, sodium lauryl sulfate, and sorbitan monolaurate.\u00a0The printing ink contains shellac, propylene glycol, indigo carmine E132 (100 mg capsule) iron oxide E172 (200 mg capsule).<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Vontents Of The Pack?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Celebra is available as hard capsules.<\/li><li>Opaque, white with two blue stripes, marked with 7767 and 100 (Celebra 100 mg).<\/li><li>Opaque, white with two yellow stripes, marked with 7767 and 200 (Celebra 200 mg).<\/li><li>The capsules are packaged in transparent or opaque PVC \/ aluminum blisters.<\/li><li>Celebra is available in packs of 2, 5, 6, 10, 20, 30, 40, 50, 60, 100, 10 \u00d7 10, 10 \u00d7 30, 10 \u00d7 50, 1 \u00d7 50 (single dose), 1 \u00d7 100 (single dose) , 5x (10&#215;10).<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Pfizer AB<\/p>\n\n\n\n<p>191 90 Sollentuna<\/p>\n\n\n\n<p>Tel: 08-550 520 00<\/p>\n\n\n\n<p>Email: eumedinfo@pfizer.com<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>R-Pharm Germany GmbH<\/p>\n\n\n\n<p>Heinrich-Mack-Str.&nbsp;35, 89257 Illertissen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Pfizer Manufacturing Deutschland GmbH<\/p>\n\n\n\n<p>Company Freiburg<\/p>\n\n\n\n<p>Mooswaldallee 1, 79090 Freiburg<\/p>\n\n\n\n<p>Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Celebra is used to treat mild to moderate pain and to assist in alleviating arthritic symptoms such as inflammation, oedema, stiffness, and joint discomfort.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[2240,7571,7574,7573,7551,7554,7553,2212,7572,7552],"class_list":["post-6596","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-capsules","tag-celebra","tag-celebra-capsule","tag-celebra-side-effects","tag-celecoxib","tag-celecoxib-capsule","tag-celecoxib-side-effects","tag-medicine","tag-what-is-celebra","tag-what-is-celecoxib"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6596","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6596"}],"version-history":[{"count":74,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6596\/revisions"}],"predecessor-version":[{"id":52241,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6596\/revisions\/52241"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6596"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6596"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}