{"id":6536,"date":"2021-01-09T09:52:37","date_gmt":"2021-01-09T09:52:37","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6536"},"modified":"2021-06-17T07:37:20","modified_gmt":"2021-06-17T07:37:20","slug":"casodex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/casodex\/","title":{"rendered":"Casodex &#8211; Bicalutamide uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n50 mg&nbsp;film-coated tablet&nbsp;<br>bicalutamide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Casodex is and what it is used for<\/h2>\n\n\n\n<p>For the growth of prostate tumors, stimulation of male sex hormones (&nbsp;androgens&nbsp;) is&nbsp;needed.&nbsp;Casodex prevents that stimulation.<\/p>\n\n\n\n<p>Casodex 50 mg tablets are used for prostate cancer in combination with castration therapy (&nbsp;GnRH&nbsp;agonist&nbsp;).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Casodex<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Casodex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to bicalutamide or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are a woman or a child.<\/li><li>if you are taking medicines containing any of the active substances terfenadine, astemizole, or cisapride.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Casodex:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have any of the following: cardiovascular disease, including heart rhythm problems (&nbsp;arrhythmias&nbsp;), or you are taking medication for this.&nbsp;The risk of heart rhythm disorders may be increased when using Casodex.<\/li><li>if you have any disease that affects the liver.<\/li><li>if you have&nbsp;diabetes&nbsp;(which may affect the amount of&nbsp;glucose&nbsp;in your blood).<\/li><li>if you are taking Casodex, you and\/or your partner should use contraception while taking Casodex and 130 days after stopping taking Casodex.&nbsp;Talk to your doctor if you have any questions about contraception.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Casodex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p>Casodex may affect or be affected by certain medicines that contain the following active substances:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ciclosporin, used in transplants<\/li><li>calcium channel blockers,&nbsp;antihypertensives<\/li><li>cimetidine, antacids<\/li><li>ketoconazole,&nbsp;antifungal<\/li><li>warfarin, a blood thinner<\/li><\/ul>\n\n\n\n<p>Casodex may affect some other medicines used to treat heart rhythm disorders (eg&nbsp;quinidine,&nbsp;procainamide,&nbsp;amiodarone,&nbsp;and sotalol) or may increase the risk of heart rhythm disorders when used with other medicines (eg&nbsp;methadone&nbsp;(used for pain and in case of treatment of drug addiction), moxifloxacin (an&nbsp;antibiotic&nbsp;), antipsychotics (used for severe mental illness).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Casodex should not be used by women.<br><\/p>\n\n\n\n<p>Casodex may transiently affect male&nbsp;fertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Casodex is likely to have no or negligible influence on your ability to drive or use machines.&nbsp;However, fatigue may occur during treatment with Casodex.&nbsp;You are responsible for assessing whether you can drive motor vehicles or perform work that requires sharpened vigilance.&nbsp;One of the factors that can affect this ability is the use of drugs due to their effects and\/or&nbsp;side effects&nbsp;.&nbsp;A description of these effects and&nbsp;side effects&nbsp;can be found under other headings in the package leaflet.&nbsp;Therefore, read all information in this leaflet.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Casodex contains lactose.<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Casodex<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.&nbsp;Dose&nbsp;one is determined by the doctor, who adjusts it individually for you.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;is one tablet a day.&nbsp;The tablets should be swallowed whole with liquid and can be taken with food.&nbsp;Try to take your medication at about the same time each day.<\/p>\n\n\n\n<p>Do not stop taking your medicine, even if you feel well unless you are immediately told by your doctor to stop.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Casodex<\/h2>\n\n\n\n<p>If you miss a&nbsp;dose, skip it and take your usual&nbsp;dose&nbsp;at the next regular dosing session.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop taking Casodex and contact a doctor immediately if you get any of the following symptoms (&nbsp;angioedema&nbsp;):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, tongue, or throat;&nbsp;difficulty swallowing;&nbsp;hives&nbsp;and difficulty breathing.<br>Angioedema&nbsp;is a less common side effect (affects less than 1 in 100 people treated with bicalutamide).<\/li><\/ul>\n\n\n\n<p><strong>Contact a doctor or seek medical attention immediately if you experience any of the following:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty breathing or sudden shortness of breath, possibly with cough or fever.&nbsp;You may have pneumonia&nbsp;called &#8220;interstitial lung disease&#8221;, this is a less common side effect (affects less than 1 in 100 people treated with bicalutamide).<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may also occur:<br><\/p>\n\n\n\n<p><em>Very common<\/em>&nbsp;(more than 1 person in 10 affected):&nbsp;Anemia, dizziness, hot flashes, abdominal pain, constipation, nausea, blood in the urine, tenderness in the breasts, enlarged breasts, weakness, fluid accumulation in the&nbsp;tissues.<br><\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;(more than 1 person in 100 affected): Decreased appetite, decreased sexual desire, depression, drowsiness, heart attack,&nbsp;heart failure, altered liver values, yellowed skin and eyes (jaundice), hair loss, increased body hair growth, dry skin,&nbsp;itching, rash,&nbsp;impotence, weight gain, chest pain, general stomach upset, flatulence.<br><\/p>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(less than 1 in 100 people affected):&nbsp;A hypersensitivity reaction.<br><\/p>\n\n\n\n<p><em>Rare<\/em>&nbsp;(less than 1 person in 1,000 affected): Photosensitivity reactions in the skin.&nbsp;Liver failure, deaths have been reported.<br><\/p>\n\n\n\n<p><em>Has been reported<\/em>: Changes (&nbsp;QT&nbsp;prolongation) in&nbsp;ECG&nbsp;(&nbsp;electrocardiogram&nbsp;).<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Casodex<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is bicalutamide 50 mg per tablet.<\/li><li>The other ingredients are&nbsp;lactose&nbsp;monohydrate 61 mg, sodium starch glycolate, povidone, magnesium stearate, hypromellose, macrogol, titanium dioxide (dye E171).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The tablet is white, marked with Cdx 50 on one side and with an arrow on the other side.<\/p>\n\n\n\n<p>Packaging:<\/p>\n\n\n\n<p>Pressure pack with 30 and 100 tablets.<\/p>\n\n\n\n<p>Printed packaging with 28 and 98 tablets,&nbsp;calendar packaging.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Sales: AstraZeneca AB, 151 85 S\u00f6dert\u00e4lje<br><\/p>\n\n\n\n<p>Manufacturer: AstraZeneca AB, S\u00f6dert\u00e4lje, or AstraZeneca Limited, Macclesfield, United Kingdom<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the growth of prostate tumors, stimulation of male sex hormones ( androgens ) is needed. Casodex prevents that stimulation.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2203,2200],"tags":[7693,7695,7696,7697,7699,7700,2212,2211,7694,7698],"class_list":["post-6536","post","type-post","status-publish","format-standard","hentry","category-c","category-medicines","tag-bicalutamide","tag-bicalutamide-side-effects","tag-bicalutamide-tablet","tag-casodex","tag-casodex-side-effects","tag-casodex-tablet","tag-medicine","tag-tablets","tag-what-is-bicalutamide","tag-what-is-casodex"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6536"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6536\/revisions"}],"predecessor-version":[{"id":11592,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6536\/revisions\/11592"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}