{"id":6353,"date":"2021-01-05T09:54:55","date_gmt":"2021-01-05T09:54:55","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6353"},"modified":"2023-02-25T16:04:51","modified_gmt":"2023-02-25T16:04:51","slug":"buvidal","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/buvidal\/","title":{"rendered":"Buvidal &#8211; Buprenorphine Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong> Buvidal 8 mg, 16 mg, 24 mg, 32 mg, 64 mg, 96 mg and 128 mg&nbsp;injection&nbsp;buprenorphine transdermal solution&nbsp;<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Is Buvidal And What Is Buvidal Used For?<\/h2>\n\n\n\n<p>Buvidal contains the active substance buprenorphine, a type of opioid medicine.\u00a0<strong>It treats opioid dependence in patients who receive medical, social and psychological support.<\/strong> Buvidal is intended for adults and adolescents aged 16 years or older.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Get Buvidal?<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You Must Not Be Given Buvidal:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to buprenorphine or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If you have severe breathing problems<\/li><li>If you have severe liver problems<\/li><li>If you are intoxicated by alcohol or have: <ul><li>Tremors<\/li><li>Sweating<\/li><li>Anxiety<\/li><li>Confusion<\/li><li>Hallucinations caused by alcohol<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings nd Cautions:<\/h2>\n\n\n\n<p>Talk to your doctor before using Buvidal if you have the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Asthma\u00a0or other respiratory problems<\/li><li>Any liver disease, such as\u00a0hepatitis<\/li><li>Severe renal impairment<\/li><li>Certain heart rhythm conditions (long\u00a0QT\u00a0syndrome or prolonged\u00a0QT interval\u00a0)<\/li><li>Low\u00a0blood pressure<\/li><li>Has recently suffered a head injury or brain disease<\/li><li>Urinary tract problems (mainly associated with enlarged\u00a0prostate\u00a0in men)<\/li><li>Thyroid problems<\/li><li>An adrenal cortex\u00a0disease\u00a0(e.g.,\u00a0Addison&#8217;s disease\u00a0)<\/li><li>Gallbladder problems<\/li><li>Depression or other conditions treated with antidepressants<\/li><\/ul>\n\n\n\n<p>If these medicines are used together with Buvidal, this may lead to serotonergic syndrome, a condition that can be life-threatening (see &#8220;Other medicines and Buvidal&#8221;).<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Important things to know<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Respiratory problems:<\/strong>\u00a0Some people have died due to very slow or shallow breathing caused by the use of buprenorphine with other substances that suppress the\u00a0central nervous system\u00a0(substances that slow down certain brain activity), such as\u00a0benzodiazepines\u00a0(medicines used to treat anxiety or sleep problems), alcohol or other\u00a0opioids\u00a0.<\/li><li><strong>Drowsiness:<\/strong>\u00a0This medicine may cause drowsiness, especially when used with alcohol or other substances that suppress the\u00a0central nervous system\u00a0(substances that slow down certain brain activity), such as\u00a0benzodiazepines\u00a0, other medicines that suppress anxiety or cause drowsiness, pregabalin or gabapentin.<\/li><li><strong>Addiction:<\/strong>\u00a0This drug can cause addiction.<\/li><li><strong>Liver damage:<\/strong>\u00a0Liver damage can occur with buprenorphine, especially if used incorrectly.\u00a0Liver damage can also occur due to viral infections (\u00a0chronic\u00a0hepatitisC), alcohol abuse,\u00a0anorexia\u00a0(loss of appetite, eating disorder) or the use of other drugs that can damage the liver.\u00a0Your doctor may ask you to have regular blood tests to check your liver.\u00a0Tell your doctor if you have any liver problems before starting treatment with Buvidal.<\/li><li><strong>Withdrawal symptoms:<\/strong>\u00a0This medicine may cause withdrawal symptoms if you take it earlier than 6 hours after using a short-acting\u00a0opioid\u00a0(eg morphine, heroin) or earlier than 24 hours after using a long-acting\u00a0opioid\u00a0such as\u00a0methadone\u00a0.<\/li><li><strong>Blood pressure:<\/strong>\u00a0This medicine may cause your\u00a0blood pressure\u00a0to\u00a0drop suddenly, causing you to feel dizzy if you get up quickly from a sitting or lying position.<\/li><li><strong>Diagnosis of unrelated medical conditions:<\/strong>\u00a0This drug can mask pain and make it difficult to diagnose certain diseases.\u00a0Do not forget to tell your doctor that you are being treated with this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People:<\/h2>\n\n\n\n<p>Buvidal must not be used by children under 16 years of age.\u00a0Your doctor will monitor you more closely if you are a young person (16 17 years old).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Buvidal:<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken or might take any other medicines. Some medicines may aggravate the\u00a0side effects\u00a0of Buvidal and may cause very serious reactions.<\/p>\n\n\n\n<p><strong>It is especially important that you tell your doctor if you are taking:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Benzodiazepines<\/strong>\u00a0(used to treat anxiety or sleep problems).\u00a0Taking too muchbenzodiazepines\u00a0with Buvidal can lead to death as both medicines can cause very slow and shallow breathing (\u00a0respiratory depression\u00a0).\u00a0If you need to take a benzodiazepine medicine, your doctor will prescribe the correct\u00a0dose\u00a0.<\/li><li>Gabapentinoids\u00a0\u00a0(gabapentin or pregabalin)\u00a0(used to treat\u00a0epilepsy\u00a0or nerve pain).\u00a0Taking too much gabapentinoid can lead to death as both drugs can cause very slow and shallow breathing (\u00a0respiratory depression\u00a0).\u00a0You must use thebuvidal dose prescribed by\u00a0your\u00a0doctor.<\/li><li>Alcohol or medicines containing alcohol\u00a0.\u00a0Alcohol may aggravate the sedative effect of this medicine.<\/li><li>Other medicines that can make you feel sleepy\u00a0and are used to treat diseases such as anxiety, insomnia, seizures and pain.\u00a0Taking these medicines with Buvidal can slow down certain brain activity, reduce alertness and affect how well you can drive and use machines.Examples of medicines that can make you sleepy or less awake are, e.g.:<ul><li>Other opioid drugs such as\u00a0methadone\u00a0, certain painkillers and antitussives.\u00a0These drugs may also increase the risk of an opioid overdose<\/li><li>Antidepressants (used to treat depression)<\/li><li>Sedative\u00a0antihistamines\u00a0(used to treat allergic reactions)<\/li><li>Barbiturates\u00a0(used as a sleeping pill or sedative)<\/li><li>Certain anti-anxiety drugs (used to treat anxiety)<\/li><li>Antipsychotics (used to treat mental illnesses such as schizophrenia)<\/li><li>Clonidine\u00a0(used to treat high\u00a0blood pressure\u00a0)<\/li><\/ul><\/li><li>Analgesic opioid drugs\u00a0.\u00a0These medicines may not work properly when taken with Buvidal and may increase the risk of an overdose.<\/li><li>Naltrexone and nalmefene\u00a0(used to treat addiction) as they may prevent Buvidal from working properly.\u00a0You should not take them while taking this medicine.<\/li><li>Some antiretroviral drugs\u00a0(used to treat\u00a0HIV\u00a0&#8211;\u00a0infection\u00a0) such as ritonavir, nelfinavir or indinavir, since they can increase the effect of this drug.<\/li><li>Certain antifungal drugs\u00a0(used to treat fungal infections), such as\u00a0ketoconazole\u00a0, itraconazole because they may increase the effects of this drug.<\/li><li>Antibiotics\u00a0called\u00a0macrolide\u00a0s\u00a0(used to treat bacterial\u00a0infection\u00a0), such as clarithromycin and erythromycin, may increase the drug&#8217;s effects.<\/li><li>Certain antiepileptic drugs\u00a0(used to treat\u00a0epilepsy\u00a0), such as phenobarbital, carbamazepine and\u00a0phenytoin, may reduce the effect of Buvidal.<\/li><li>Rifampicin\u00a0(used to treat\u00a0tuberculosis\u00a0).\u00a0Rifampicin may reduce the effect of Buvidal.<\/li><li>Monoamine oxidase inhibitors\u00a0(used to treat depression) such as phenelzine, isocarboxazide, iproniazid and tranylcypromine as they may potentiate the effect of this medicine.<\/li><li>Antidepressants\u00a0include moclobemide, tranylcypromine,\u00a0citalopram\u00a0, escitalopram,\u00a0fluoxetine\u00a0, fluvoxamine,\u00a0paroxetine\u00a0,\u00a0sertraline\u00a0, duloxetine,\u00a0venlafaxine\u00a0, amitriptyline, doxepine or trimipramine.\u00a0These medicines can affect or be affected by Buvidal and you may experience symptoms such as involuntary rhythmic muscle twitching, even in the muscles that control eye movements, agitation, hallucinations,\u00a0coma\u00a0, heavy sweating, tremors, increased reflexes, tense muscles and body temperature above 38 \u00b0 C.\u00a0Contact your doctor if you experience such symptoms.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Buvidal With Alcohol<\/h2>\n\n\n\n<p>Drinking alcohol with this medicine may cause drowsiness and increase the risk of breathing problems.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding:<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0The risks of using Buvidal in pregnant women are not known.\u00a0Your doctor will help you decide if you should continue to take this medicine during pregnancy.<\/p>\n\n\n\n<p>Taking this medicine during advanced pregnancy may cause withdrawal symptoms and also breathing problems in your newborn baby.\u00a0This can occur from several hours to several days after delivery.<br>Talk to your doctor before using Buvidal during breast-feeding as this medicine passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines:<\/h2>\n\n\n\n<p>Buvidal can make you sleepy and dizzy.\u00a0This is likely at the beginning of treatment and when your\u00a0dose\u00a0changes.\u00a0These effects may be exacerbated by drinking alcohol or taking other sedatives.\u00a0Do not drive, use tools or machines or perform dangerous activities until you know how this medicine affects you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Buvidal Contains Alcohol:<\/h2>\n\n\n\n<p>Buvidal 8 mg, 16 mg, 24 mg and 32 mg contain small amounts of\u00a0ethanol\u00a0(alcohol), less than 100 mg per\u00a0dose\u00a0.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How Buvidal Is Given?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Healthcare professionals should only give Buvidal.<\/li><li>Buvidal 8 mg, 16 mg, 24 mg and 32 mg are given weekly.\u00a0Buvidal 64 mg, 96 mg and 128 mg are given monthly.<\/li><li>Your doctor will decide which\u00a0buvidal dose is best for you.\u00a0Your doctor may adjust the dose during your treatment depending on how well the medicine works.<\/li><\/ul>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Initial treatment<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The first\u00a0dose\u00a0of Buvidal will be given to you when you show clear signs of\u00a0abstinence.<\/li><li>If you are addicted to short-acting\u00a0opioids\u00a0(e.g., morphine or heroin), the first\u00a0dose\u00a0will be given at least 6 hours after using an\u00a0opioid.<\/li><li>If you are addicted to long-acting\u00a0opioids\u00a0(e.g.,\u00a0methadone\u00a0), your methadone dose will be reduced to less than 30 mg per day before you start taking Buvidal.\u00a0The first\u00a0dose of\u00a0one of these medicines will be given to you at least 24 hours after you last used\u00a0methadone. Suppose you are not already getting sublingually (under the tongue) buprenorphine (the same active substance as in Buvidal). In that case, the recommended starting dose is 16 mg, with one or two additional\u00a0doses\u00a0of Buvidal 8 mg given at least 1 day apart during the first week of treatment.\u00a0This means a target dose of 24 or 32 mg during the first week of treatment.<\/li><li>If you have not used buprenorphine before, you will be given a\u00a0sublingualbuprenorphine dose of 4 mg and observed for one hour before receiving the first\u00a0dose\u00a0of Buvidal.<\/li><li>Buvidal for monthly treatment can be used, if this is convenient for you, when stabilization has been achieved with Buvidal for weekly treatment (after four weeks of treatment or more, when possible).<\/li><li>If you already take sublingual buprenorphine, you can start receiving Buvidal the day after your last treatment.\u00a0Your doctor will prescribe the correct starting dose of Buvidal for you, depending on the\u00a0dose of\u00a0sublingual buprenorphine you are taking now.<\/li><\/ul>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Continuation of treatment and dose adjustment<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>During continued treatment with Buvidal, your doctor may reduce or increase your\u00a0dose\u00a0as needed.\u00a0You can change from weekly to monthly treatment and from monthly to weekly treatment.\u00a0Your doctor will prescribe the correct\u00a0dose\u00a0for you.<\/li><li>During further treatment, you may receive an additional\u00a0dose\u00a0of Buvidal 8 mg between your weekly or monthly treatments if your doctor thinks it is appropriate for you.<\/li><li>The maximum\u00a0dose\u00a0one per week, if you are on weekly treatment with Buvidal, is 32 mg with an additional\u00a0dose\u00a0of 8 mg.\u00a0If you are on monthly treatment with Buvidal, the maximum dose once a month is 128 mg with an additional\u00a0dose\u00a0of 8 mg.<\/li><\/ul>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>How is the product given<\/strong>?<\/span><\/p>\n\n\n\n<p>Buvidal is given as an&nbsp;injection&nbsp;under the skin (&nbsp;subcutaneously&nbsp;) in one of the permitted injection areas of the buttocks, thighs, abdomen or upper arm.&nbsp;You can get several&nbsp;injections&nbsp;in the same injection area, but the exact injection site will be different for each weekly and monthly injection for at least 8 weeks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Buvidal Than You Should:<\/h2>\n\n\n\n<p>If you have been given more buprenorphine than you should, contact a doctor immediately, as this can cause very slow and shallow breathing, leading to death.<\/p>\n\n\n\n<p>If you have used too much buprenorphine, you must seek medical attention immediately, as an overdose can cause serious and life-threatening breathing problems.<\/p>\n\n\n\n<p>Symptoms of an overdose may be slower and weaker breathing than normal, that you feel more sleepy than normal, smaller\u00a0pupils\u00a0, that you begin to feel dizzy as this may be a sign of low\u00a0blood pressure\u00a0, nausea, vomiting and slurred speech.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Miss A Dose Of Buvidal:<\/h2>\n\n\n\n<p>It is very important to remember all booked visits to get Buvidal.\u00a0If you miss a visit, ask your doctor when to plan your next\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Taking Buvidal:<\/h2>\n\n\n\n<p>Do not stop treatment without consulting your doctor.\u00a0Discontinuation of treatment may lead to withdrawal symptoms.\u00a0Ask your doctor if you have any further questions about using this product.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Buvidal Injection Side Effects:<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them. Tell\u00a0your\u00a0doctor immediately or seek\u00a0emergency\u00a0medical advice\u00a0if you get\u00a0any side effects\u00a0, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden wheezing, difficulty breathing, swelling of eyelids, face, tongue, lips, throat or hands;\u00a0rash or\u00a0itching\u00a0especially all over the body.\u00a0These can be signs of a life-threatening\u00a0allergic reaction.<\/li><li>If you start breathing slower or weaker than usual (\u00a0respiratory depression\u00a0).<\/li><li>If you start to feel dizzy, this may indicate low\u00a0blood pressure.<\/li><li>Also, tell your doctor immediately if you experience any\u00a0side effects\u00a0such as:<ul><li>Severe fatigue<\/li><li>Poor appetite, or if your skin or eyes are yellow.\u00a0These can be symptoms of liver damage.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Other side effects:<\/strong> <em>Very common (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Insomnia (inability to sleep)<\/li><li>Headache<\/li><li>Nausea<\/li><li>Sweating, withdrawal syndrome, pain<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection,\u00a0flu, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">sore throat<\/a> and sore throat, runny nose<\/li><li>Swollen\u00a0glands\u00a0(\u00a0lymph nodes\u00a0)<\/li><li>Hypersensitivity<\/li><li>Decreased appetite<\/li><li>Anxiety, upset, depression, hostility, nervousness, abnormal thinking,\u00a0paranoia<\/li><li>Drowsiness, dizziness,\u00a0migraine, burning or tingling in the hands and feet, fainting, tremors, increased muscle tension, speech disorders<\/li><li>Watery eyes, abnormal dilation or contraction of\u00a0pupil\u00a0one (the dark part in the middle of the eye)<\/li><li>Palpitation<\/li><li>Low\u00a0blood pressure<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">Cough<\/a>, shortness of breath, yawning,\u00a0asthma\u00a0,\u00a0bronchitis\u00a0(\u00a0tracheal catarrh\u00a0)<\/li><li>Constipation, vomiting, abdominal pain, gas in the stomach, indigestion,\u00a0dry mouth\u00a0, diarrhea<\/li><li>Rash,\u00a0itching\u00a0,\u00a0hives<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a>, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/back-hurts\/\">back pain<\/a>, muscle pain, muscle spasms, neck pain, skeletal pain<\/li><li>Painful menstruation<\/li><li>Injection site reactions such as\u00a0pain,\u00a0itching\u00a0,\u00a0reddened\u00a0skin, swelling or hardened skin;\u00a0swollen ankles, feet or fingers;\u00a0weakness;\u00a0feel bad;\u00a0fever;\u00a0overindulge;\u00a0abstinence syndrome in newborns;\u00a0chest pain<\/li><li>Deviating results on liver samples<\/li><\/ul>\n\n\n\n<p><em><strong>Uncommon (may affect up to 1 in 100 people):<\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Skin infection at the injection site<\/li><li>Feeling dizzy or spinning (&nbsp;vertigo&nbsp;)<\/li><\/ul>\n\n\n\n<p><em><strong>Has been reported (occurs in an unknown number of users):<\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hallucinations<\/li><li>Feeling happy and elated (\u00a0euphoria\u00a0)<\/li><li>Abnormal skin redness<\/li><li>Painful or difficult to urinate<\/li><\/ul>\n\n\n\n<p><em><strong>Reporting of side effects<\/strong><\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Buvidal?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Healthcare professionals should only give Buvidal.\u00a0Patients&#8217; use at home or self-administration of the product is not permitted.<\/li><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton or syringe label after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store in a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">cold<\/a> place.\u00a0Do not freeze.<br>Do not use this medicine if you notice visible particles or if it is cloudy.<\/li><li>Buvidal is for single use only.\u00a0All used syringes should be discarded.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information:<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is buprenorphine<\/li><li>The other ingredients are soybean phosphatidylcholine, glycerol dioleate, anhydrous&nbsp;ethanol&nbsp;(only in Buvidal for weekly treatment and N-methylpyrrolidone (only in Buvidal for monthly treatment).<\/li><\/ul>\n\n\n\n<p><strong>The following syringes are available:<\/strong><\/p>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Injection\u00a0once a week:<\/span><\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>8 mg: Pre-filled\u00a0syringe\u00a0containing 8 mg buprenorphine in 0.16 ml solution<\/li><li>16 mg: Pre-filled\u00a0syringe\u00a0containing 16 mg buprenorphine in 0.32 ml solution<\/li><li>24 mg: Pre-filled\u00a0syringe\u00a0containing 24 mg buprenorphine in 0.48 ml solution<\/li><li>32 mg: Pre-filled\u00a0syringe\u00a0containing 32 mg buprenorphine in 0.64 ml solution<\/li><\/ul>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Injection\u00a0once a month:<\/span><\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>64 mg: Pre-filled\u00a0syringe\u00a0containing 64 mg buprenorphine in 0.18 ml solution<\/li><li>96 mg: Pre-filled\u00a0syringe\u00a0containing 96 mg buprenorphine in 0.27 ml solution<\/li><li>Buvidal 128 mg: Pre-filled\u00a0syringe\u00a0containing 128 mg buprenorphine in 0.36 ml solution<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And Contents Of The Pack?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Buvidal is a\u00a0solution for injection\u00a0.\u00a0Each pre-filled\u00a0syringe\u00a0contains a yellowish to yellow translucent liquid.<\/li><li>The following pack sizes are available:<ul><li>Pre-filled syringes containing 8 mg, 16 mg, 24 mg, 32 mg, 64 mg, 96 mg and 128 mg\u00a0solution for injection\u00a0, prolonged-release solution.<\/li><li>Each pack contains 1 pre-filled\u00a0syringe\u00a0with rubber stopper, needle, needle guard, safety unit and 1 plunger rod.<\/li><\/ul><\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Buvidal is a medication used to treat opioid (narcotic) drug addiction, such as heroin or morphine. Buvidal is prescribed to adults and adolescents over the age of 16 who are simultaneously getting medical, social, and psychological care.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[3584,8116,3587,8117,8120,8115,8119,8114,8118],"class_list":["post-6353","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-buprenorphine","tag-buprenorphine-injection","tag-buprenorphine-side-effects","tag-buvidal","tag-buvidal-injection","tag-what-buprenorphine-is-used-for","tag-what-buvidal-is-used-for","tag-what-is-buprenorphine","tag-what-is-buvidal"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6353","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6353"}],"version-history":[{"count":59,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6353\/revisions"}],"predecessor-version":[{"id":51953,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6353\/revisions\/51953"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6353"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6353"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}