{"id":6288,"date":"2021-01-04T15:15:43","date_gmt":"2021-01-04T15:15:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6288"},"modified":"2023-02-21T14:28:17","modified_gmt":"2023-02-21T14:28:17","slug":"bunalict","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bunalict\/","title":{"rendered":"Bunalict &#8211; Buprenorphine \/ Naloxone Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Bunalict 2 mg\/0.5 mg, 8 mg\/2 mg&nbsp;Buprenorphine\/Naloxone Sublingual<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Is Bunalict And What Bunalict Used For?<\/h2>\n\n\n\n<p>Bunalict used for drug addicts addicted to opiate drugs (narcotics) such as heroin or morphine, who have consented to be treated for their addiction.\u00a0Bunalict treatment is intended for adults and adolescents over 15 who receive medical, social, and psychological support.<\/p>\n\n\n\n<p>Buprenorphine and naloxone contained in Bunalict may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Taking Bunalict?<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Bunalict:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to buprenorphine, naloxone, or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have\u00a0severe breathing problems<\/li><li>If you have\u00a0severe liver problems<\/li><li>If you are under the influence of alcohol or suffer from tremors, sweating, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/anxiety-strong-feelings-of-worry\/\">anxiety<\/a>, confusion, or hallucinations caused by alcohol<\/li><li>If you are taking naltrexone or nalmefene for the treatment of alcohol or opiate dependence.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions:<\/h2>\n\n\n\n<p><strong>Talk to your doctor before taking Bunalict if you have the following:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Asthma\u00a0or other respiratory problems<\/li><li>A liver disease, e.g.\u00a0hepatitis<\/li><li>Low\u00a0blood pressure<\/li><li>A recent head injury or brain disease<\/li><li>Urinary tract problems (mainly associated with an enlarged\u00a0prostate\u00a0in men)<\/li><li>A kidney disease<\/li><li>Thyroid problems<\/li><li>Adrenocortical disorders (eg\u00a0Addison&#8217;s disease\u00a0).<\/li><\/ul>\n\n\n\n<p>Never open the blister in advance. Contact an emergency department immediately in case of accidental ingestion or suspected ingestion.<strong><br>Important things to keep in mind:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Your<\/strong> doctor can follow you up more closely if you are under 18 or over 65.\u00a0People under the age of 15 must not take this medicine.<\/li><li>Misuse and abuse of this medicine may be desirable for people abusing prescription drugs, and it should be stored in a safe place to protect against theft.\u00a0Never give the medicine to anyone; it could lead to death or injury.<\/li><li>Some people have died of\u00a0respiratory <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a>\u00a0(severe difficulty breathing) due to misuse of this drug, or that they took it together with drugs that affect the\u00a0central nervous system.\u00a0Alcohol,\u00a0benzodiazepines\u00a0(sedatives), or other\u00a0opioids.<br>This medicine can cause severe, possibly fatal respiratory paralysis (difficulty breathing) in children and people who do not have an addiction and take medicine intentionally or unintentionally.<\/li><li>DependentThis medicine may be addictive.<\/li><li>Withdrawal symptoms This medicine may cause withdrawal symptoms if you take it earlier than 6 hours after using a short-acting\u00a0opioid\u00a0(eg morphine or heroin) or earlier than 24 hours after using a long-acting\u00a0opioid\u00a0such as methadone.<br>Bunalict can also cause withdrawal symptoms if you stop taking them suddenly.<\/li><li>Liver damage has been reported with Bunalict, especially if the medicine is used incorrectly.\u00a0These liver damages can also be due to viral infections (chronic hepatitis C), alcohol abuse, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/anorexia\/\">anorexia<\/a> or the use of other drugs that can damage the liver (listed in section 4).\u00a0Doctors may perform regular blood tests to monitor the condition of your liver.\u00a0Tell your doctor if you have liver problems before starting treatment with Bunalict.<\/li><li>This medicine may cause blood pressure to drop rapidly, making you feel dizzy if you get up quickly from a sitting or lying position.<\/li><li>Diagnosis of unrelated medical conditions,<strong> <\/strong>this medicine can hide <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> which is a sign of certain diseases.\u00a0Remember to tell your doctor that you are taking this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Bunalict:<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take other medicines. Some medicines can aggravate the\u00a0side effects\u00a0of Bunalict and sometimes cause serious reactions.\u00a0Do not take any other medicines while you are taking Bunalict without talking to a doctor first, especially:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Concomitant use of Bunalict and\u00a0<strong>sedatives or medicines for insomnia,<\/strong> such as\u00a0benzodiazepines\u00a0or similar medicines,\u00a0increases the risk of drowsiness, difficulty breathing (\u00a0breathing depression\u00a0),\u00a0coma\u00a0and can be life-threatening.\u00a0Due to this, concomitant use should only be considered when other treatment options are not possible.\u00a0<br>If your doctor prescribes Bunalict at the same time as sedatives, the\u00a0dose\u00a0and treatment time\u00a0should be\u00a0limited by your doctor. Tell your doctor if you are taking any sedatives, and follow your doctor&#8217;s dose recommendations.\u00a0It may be helpful to inform friends or relatives about paying attention to the signs and symptoms described above.\u00a0Contact a doctor if you experience any of these symptoms.<\/li><li>Other medications that can make you <strong>sleepy are used to treat illnesses such as anxiety, insomnia, seizures,<\/strong> or pain.\u00a0These types of medications reduce your alertness, which can make driving vehicles and using machines risky.\u00a0They can also cause depression of the CNS (\u00a0central nervous system\u00a0), which is very serious.\u00a0Below is a list of examples of these types of drugs:<ul><li>Other opioid-containing medications, e.g.\u00a0methadone, some painkillers, and antitussives<\/li><li>Antidepressants (used to treat depression), e.g.\u00a0isocarboxazid, phenelzine,\u00a0selegiline, tranylcypromine, and\u00a0valproate, may potentiate the effects of this medicine.<\/li><li>Sedative\u00a0H 1 receptor antagonists (used to treat allergic reactions), e.g.\u00a0diphenhydramine and chlorphenamine<\/li><li>Barbiturates (used to induce sleep or\u00a0sedation\u00a0), e.g.\u00a0phenobarbital and secobarbital<\/li><li>Sedatives (used to induce sleep or sedation), e.g.\u00a0chloral hydrate<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Clonidine\u00a0(used to treat high\u00a0blood pressure\u00a0) may prolong the effects of this medicine<\/li><li>Antiretroviral agents (used to treat HIV), e.g.\u00a0ritonavir, nelfinavir, and indinavir, may prolong the effects of this medicine<\/li><li>Certain\u00a0antifungals\u00a0(used to treat fungal infections), e.g.\u00a0ketoconazole, itraconazole, and certain\u00a0antibiotics, may prolong the effects of this medicine<\/li><li>Some medicines may reduce the effect of Bunalict.\u00a0They include medicines to treat epilepsy (eg carbamazepine and\u00a0phenytoin\u00a0), as well as medicines to treat tuberculosis (rifampicin).<\/li><li>Naltrexone and nalmefene (medicines used to treat addiction) may counteract the therapeutic effects of Bunalict.\u00a0They should not be taken with Bunalict treatment because you may suddenly experience prolonged and intense withdrawal symptoms.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Bunalict With Food, Drink, And Alcohol:<\/h2>\n\n\n\n<p>Alcohol may increase drowsiness and increase the risk of respiratory depression if taken with Bunalict.\u00a0<strong>Do not take Bunalict with alcoholic beverages.\u00a0<\/strong>\u00a0Do not consume food or drink until the travel tablet has completely dissolved.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding:<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>The risks for pregnant women using Bunalict are not known.\u00a0Tell your doctor if you are pregnant or planning to become pregnant.\u00a0Your doctor will decide if you should continue treatment with another medicine.<br>Drugs such as Bunalict can cause withdrawal symptoms and breathing problems in the newborn baby if taken during- especially advanced- pregnancy.\u00a0These problems can occur several days after birth. Do not breast-feed while taking this medicine as Bunalict passes into breast milk.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines:<\/h2>\n\n\n\n<p>Bunalict may cause drowsiness.\u00a0It can happen more often during the first weeks of treatment when the dose is changed, but it can also happen if you drink alcohol or take other sedatives while taking Bunalict.<\/p>\n\n\n\n<p>Do not drive, use tools or machines, or perform dangerous activities until you know how this medicine affects you. You are responsible for assessing whether you can drive a motor vehicle or perform work requiring sharpened attention.<\/p>\n\n\n\n<p>One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bunalict Contains:<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Bunalict contains\u00a0lactose<\/span><\/strong>: If your doctor has told you that you are intolerant to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>Bunalict contains\u00a0sodium<\/strong><\/span>: This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per travel tablet, ie is essential &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Bunalict?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>A doctor with experience treating drug addiction prescribes and monitors the treatment.<\/li><li>Your doctor will decide which\u00a0dose\u00a0is best for you.\u00a0Your doctor may adjust your dose during your treatment depending on how you react.<\/li><li>Always take this medicine exactly as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><\/ul>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Initial treatment<\/span><\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended starting dose for adults and adolescents over 15 is 1-2 Bunalict 2 mg \/ 0.5 mg resoriblets.\u00a0Depending on your needs, an additional 1-2 Bunalict 2 mg \/ 0.5 mg resoriblets may be administered on the first day.<\/li><li>Clear signs of abstinence should be obvious before taking the first\u00a0dose\u00a0of Bunalict.\u00a0The doctor&#8217;s assessment of how ready you are for treatment determines when you should receive the first\u00a0dose of\u00a0one with Bunalict.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong><span style=\"text-decoration: underline;\">Initial treatment with Bunalict during heroin addiction<\/span><\/strong><br>If you are addicted to heroin or a short-acting\u00a0opioid, the first\u00a0dose of\u00a0one of Bunalict should be taken when signs of abstinence occur, but not earlier than 6 hours before the last time you used opioids.<\/li><li><strong><span style=\"text-decoration: underline;\">Initial treatment with Bunalict during methadone dependence<\/span><\/strong><br>If you have taken methadone or a long-acting opioid, the methadone dose should preferably be reduced to less than 30 mg\/day before starting treatment with Bunalict.\u00a0The first dose of Bunalict should be taken when signs of abstinence occur, but not earlier than 24 hours after the last use of\u00a0methadone.<\/li><\/ul>\n\n\n\n<p><strong>How to take Bunalict<\/strong>?<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take the dose once a day by placing the resoriblets under the tongue.<\/li><li>Hold the travel tablet under the tongue until it is <strong>completely dissolved<\/strong>.\u00a0This may take 5-10 minutes.<\/li><li>Do not chew or swallow the resoriblets.\u00a0The drug will then not work, and it can lead to withdrawal symptoms.<\/li><li>Do not consume food or drink until the resoriblet has completely dissolved.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How To Remove The Travel Tablet From The Package<\/strong>?<\/h2>\n\n\n\n<p>1 &#8211; Do not push the tablet through the foil.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20161026000024#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/2801cd63-6fca-4352-88ab-5154101c7e0d\" alt=\".\"\/><\/a><\/figure>\n\n\n\n<p><br>2 &#8211; Remove a box of the blister pack by dragging along the perforated line.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20161026000024#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/561dca96-1991-4f63-a161-058d1346cfdd\" alt=\".\"\/><\/a><\/figure>\n\n\n\n<p>3 &#8211; Start from the edge where the seal is folded up and pull off the foil on the back to remove the travel tray.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20161026000024#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/2a43390d-230b-4a45-904e-f0dded487e86\" alt=\".\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20161026000024#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/30476646-4a38-431e-bd62-22e0a5e17cb8\" alt=\".\"\/><\/a><\/figure>\n\n\n\n<p>If the blister pack is damaged, discard the travel tablet.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Dose adjustment and maintenance treatment:<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>During the first days after\u00a0starting treatment, your\u00a0doctor may increase the\u00a0dose ofBunalict according to your needs.\u00a0If you have the impression that the effect of Bunalict is too strong or too weak, talk to your doctor or pharmacist.\u00a0The maximum daily dose is 24 mg.<\/li><li>After successful treatment, you can agree with your doctor to gradually reduce the\u00a0dose\u00a0to a lower maintenance\u00a0dose.<\/li><\/ul>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>End of treatment<\/strong>:<\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Depending on your condition, you can continue to reduce the dose of Bunalict under close medical supervision until it can be completely discontinued.<\/li><li>Do not change the treatment in any way or discontinue it without the consent of the doctor who gives you the treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Bunalict Than You Should:<\/h2>\n\n\n\n<p>Suppose you or anyone else takes too much of this medicine. In that case, you must immediately go to an emergency room or hospital for treatment, as an <strong>overdose<\/strong>\u00a0of Bunalict may cause serious and life-threatening breathing problems.<\/p>\n\n\n\n<p>Overdose symptoms may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drowsiness and incoherence with slow reflexes<\/li><li>Blurred vision<\/li><li>Slurred speech<\/li><li>You may have difficulty thinking clearly<\/li><li>Your breathing may be much slower than normal<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Bunalict<\/h2>\n\n\n\n<p>Tell your doctor as soon as possible if you miss a&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Taking Bunalict<\/h2>\n\n\n\n<p>Do not change the treatment in any way or discontinue it without the consent of the doctor who gives you the treatment.\u00a0<strong>Sudden discontinuation of treatment may lead to withdrawal symptoms.<\/strong> Ask your doctor or pharmacist if you have any further questions about using this product.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Bunalict Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Tell your doctor immediately or seek emergency care<\/strong>\u00a0\u00a0if you experience\u00a0side effects such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swollen face, lips, tongue, or throat that may make it difficult to swallow or breathe, severe hives\/rash.\u00a0This may be a sign of a life-threatening\u00a0allergic reaction.<\/li><li>The feeling of drowsiness and clumsiness, foggy vision, slurred speech, difficulty clear thinking, or breathing much slower than normal.<\/li><\/ul>\n\n\n\n<p><strong>Also,<\/strong> tell\u00a0\u00a0your doctor\u00a0immediately\u00a0if you experience side effects such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/fatigue-syndrome\/\">fatigue<\/a> or itching with yellowing skin or eyes.\u00a0It may be a sign of liver damage.<\/li><li>See or hear things that do not exist (hallucinations).<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Side effects reported for Bunalict<\/strong><\/td><\/tr><tr><td><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/td><\/tr><tr><td>Insomnia (inability to sleep), Constipation, Nausea, Heavy sweating, headache, drug with drawal syndrome.<\/td><\/tr><tr><td><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/td><\/tr><tr><td>Weight loss, swelling (hands and feet), Drowsiness, Anxiety, Nervousnes, Sknitting, Depression, Decreased sex drive muscle, Twitching, Abnormal thought sincreased, Tear flow (watery eyes) or other disturbance of tear flowdimsynhot, Flasheshigh blood pressuremigraine, Runny nose,\u00a0Sore throat and pain when swallowing increased coughupset stomach or other stomach upset, Diarrheahe, Patic impairmentgas formation, Vomiting, Rash, Itching, Hives, Pain joint, Pain muscle aches, Leg cramps, Impotence urinary incontinence abdominal painback pain weakness infection over indulge chest pain feverflu-like symptoms general malaise injury in the event of an accident caused by a reduced level of consciousness or Coordinationdullness and Dizziness.<\/td><\/tr><tr><td><strong>Uncommon<\/strong>&nbsp;&nbsp;(may affect up to 1 in 100 people):<\/td><\/tr><tr><td>Swollen glands (\u00a0lymph nodes\u00a0), Agitation, Tremorsabnormal dream, sexcessive muscle activity, Personality change (not feeling like yourself), Drug dependence, Memory loss interest, inflated sense of well-being, seizures, speech difficulties, Small, Pupils problems urinating Conjunctivitis of the eyefast or slow heart beat, Low blood pressure, Palpitation my ocardial infarction pressure over the chestshortness of breath, Asthma, yYawning pain and sores in the mouth, Discoloration of the tongue acne, Skin noduleshair lossdry or scaly skin, Arthritisurinary tract infection, Abnormal blood test results, Blood in the urine, Abnormal ejaculation, Menstrual or vaginal problem, Skidney stoneprotein in the urine, pain when urinating or difficulty urinating, Sensitivity to heat or cold heat strokeloss of appetite\u00a0feelings of hostility.<\/td><\/tr><tr><td><strong>Has been reported<\/strong>&nbsp;(occurs in the unknown number of users):<\/td><\/tr><tr><td>Sudden withdrawal syndrome caused by the Bunalict taken too soon after use of illicit\u00a0opioid\u00a0you, drug withdrawal syndrome in newborn, Slow breathing or difficulty breathing, Liver problems with or without jaundice, Hallucinations, Swelling of the face and throat or life-threatening allergic reactions, drop in blood pressure when changing position from sitting or lying to standing, Misusing the drug by\u00a0injection\u00a0may cause withdrawal symptoms,\u00a0infections\u00a0, other skin reactions and potentially serious liver problems (see \u201cWarnings and Precautions\u201d).<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em><strong>Reporting of side effects<\/strong><\/em><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This includes any possible side effects not listed in this leaflet.\u00a0You can also report side effects directly to the Medical Products Agency,\u00a0www.lakemedelsverket.se.\u00a0By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Bunalict?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight of children and other household members.<\/li><li>Do not use this medicine after the expiry date stated on the blister and carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not store above 30 \u00b0 C.\u00a0Store in the original package.\u00a0Sensitive to light.\u00a0However, Bunalict may be desirable for people who abuse prescription drugs.\u00a0Store this medicine in a safe place to protect it from theft.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are buprenorphine and naloxone.&nbsp;<br>Each 2 mg \/ 0.5 mg sublingual resoriblett contains 2 mg buprenorphine (as hydrochloride) and 0.5 mg naloxone (as hydrochloride dihydrate).&nbsp;<br>Each 8 mg \/ 2 mg sublingual resorblett contains 8 mg buprenorphine (as hydrochloride) and 2 mg naloxone (as hydrochloride dihydrate).<\/li><li>The other ingredients are&nbsp;lactose monohydrate,&nbsp;maize&nbsp;starch, mannitol (E421), povidone K30, anhydrous citric acid, sodium citrate, flavors (lemon and lime), acesulfame potassium, and sodium stearyl fumarate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like, And What Are The Pack&#8217;s Contents?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Bunalict 2 mg \/ 0.5 mg sublingual resoriblet tablets are white to off-white, round, biconvex, uncoated tablets, 6.5 mm in diameter, marked with \u201cN2\u201d on one side and the symbol \u201c\u2191\u201d on the other side.<\/li><li>Bunalict 8 mg \/ 2 mg sublingual resoriblet tablets are white to off-white, round, biconvex, uncoated tablets, 10.5 mm in diameter, marked with \u201cN8\u201d on one side and the symbol \u201c\u2191\u201d on the other side.<\/li><li>Packed in child-resistant, removable single-dose blisters of 7&#215;1, 28&#215;1, and 49&#215;1 resoriblet.<br>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Ethypharm 194, Bureaux de la Colline, Building D, 92213 Saint-Cloud, France<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Ethypharm, Chemin de la Poudri\u00e8re, 76120 Grand Quevilly, France<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Bunalict is used to treat drug addicts who have given their consent to be treated for their addiction to heroin drugs (narcotics) such as heroin or morphine.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8264,8266,3584,3587,8219,8221,8268,8190,8267,8115,8265,8114,8220,8222],"class_list":["post-6288","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-bunalict","tag-bunalict-side-effects","tag-buprenorphine","tag-buprenorphine-side-effects","tag-naloxone","tag-naloxone-side-effects","tag-side-effects-of-bunalict","tag-side-effects-of-buprenorphine","tag-what-bunalict-is-used-for","tag-what-buprenorphine-is-used-for","tag-what-is-bunalict","tag-what-is-buprenorphine","tag-what-is-naloxone","tag-what-naloxone-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6288"}],"version-history":[{"count":75,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6288\/revisions"}],"predecessor-version":[{"id":50487,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6288\/revisions\/50487"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6288"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6288"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}