{"id":6279,"date":"2021-01-04T15:08:49","date_gmt":"2021-01-04T15:08:49","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6279"},"modified":"2021-06-25T14:03:00","modified_gmt":"2021-06-25T14:03:00","slug":"budenofalk","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/budenofalk\/","title":{"rendered":"Budenofalk &#8211; Budesonide uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n9 mg&nbsp;enterogranulate&nbsp;<br>budesonide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Budenofalk granules are and what they are used for<\/h2>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;contain the active substance budesonide, a type of topical&nbsp;steroid&nbsp;used to treat&nbsp;chronic&nbsp;inflammatory bowel disease.<br><\/p>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;are used in the treatment of<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Crohn&#8217;s disease<\/strong><strong>&nbsp;:<\/strong>&nbsp;&nbsp;mild to moderate acute attacks of chronic inflammation in the lower part of the small intestine (ileum) and \/ or the upper part of the colon (ascending colon&nbsp;)<br><\/li><li><strong>acute episodes of&nbsp;collagen&nbsp;colitis<\/strong>&nbsp;(a disease with&nbsp;chronic&nbsp;inflammation&nbsp;of the colon characterized by&nbsp;chronic&nbsp;, watery diarrhea).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Budenofalk granules<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Budenofalk granules<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are&nbsp;<strong>allergic<\/strong>&nbsp;to budesonide or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have a&nbsp;<strong>serious liver disease<\/strong>&nbsp;(&nbsp;liver cirrhosis&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Budenofalk&nbsp;granules&nbsp;if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>tuberculosis<\/li><li>high&nbsp;blood pressure<\/li><li>diabetes&nbsp;, or if someone in the family has been diagnosed with&nbsp;diabetes<\/li><li>bone loss (&nbsp;osteoporosis&nbsp;)<\/li><li>ulcers in the stomach or first part of the small intestine (peptic&nbsp;ulcer&nbsp;)<\/li><li>increased pressure in the eyes (&nbsp;glaucoma&nbsp;) or eye problems such as cloudiness of the lens (&nbsp;cataract&nbsp;) or if someone in the family has been diagnosed with&nbsp;glaucoma<\/li><li>severe liver problems<\/li><\/ul>\n\n\n\n<p>Budenofalk granules are not suitable for patients with Crohn&#8217;s disease of the upper gastrointestinal tract.<br><\/p>\n\n\n\n<p>Sometimes this disease can cause symptoms outside the gut (eg affecting skin, eyes and joints).&nbsp;These symptoms are unlikely to be ameliorated by treatment with this medicine.<br><\/p>\n\n\n\n<p>Typical effects of cortisone drugs can occur and can affect all parts of the body, especially if you take Budenofalk&nbsp;granules&nbsp;in high&nbsp;doses&nbsp;and for long periods (see section 4, Possible&nbsp;side effects&nbsp;).<br><\/p>\n\n\n\n<p><strong>Additional precautions for treatment with Budenofalk granules:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor if you have an&nbsp;infection&nbsp;.&nbsp;The symptoms of some&nbsp;infections&nbsp;may deviate from normal or be unclear.<\/li><li>If you&nbsp;have not had these diseases,&nbsp;stay away from people who have chickenpox or&nbsp;herpes&nbsp;zoster (&nbsp;shingles&nbsp;).&nbsp;These can seriously affect you.&nbsp;If you come in contact with someone who has chickenpox or&nbsp;shingles&nbsp;, contact your doctor immediately.<\/li><li>Tell your doctor if you have not had measles.<\/li><li>If you know you need to get vaccinated, talk to your doctor first.<\/li><li>If you have any surgery, tell your doctor that you are taking Budenofalk&nbsp;granules&nbsp;.<\/li><li>If you have been treated with a stronger cortisone preparation before you start taking Budenofalk&nbsp;granules&nbsp;,&nbsp;your&nbsp;symptoms may return when you change medicines.&nbsp;Contact your doctor if this happens.<\/li><li>Contact a doctor if you experience blurred vision or other visual disturbances.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Budenofalk granules<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Particularly:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>cardiac glycosides<\/strong>&nbsp;such as&nbsp;digoxin&nbsp;(medicines used to treat heart disease)<\/li><li><strong>diuretics<\/strong>&nbsp;(to remove excess fluid from the body)<\/li><li><strong>ketoconazole&nbsp;or itraconazole<\/strong>&nbsp;(to treat fungal infections)<\/li><li><strong>antibiotics<\/strong>&nbsp;to treat&nbsp;infections&nbsp;(eg clarithromycin)<\/li><li><strong>carbamazepine<\/strong>&nbsp;(to treat&nbsp;epilepsy&nbsp;)<\/li><li><strong>rifampicin<\/strong>&nbsp;(to treat&nbsp;tuberculosis&nbsp;)<\/li><li><strong>estrogen&nbsp;or&nbsp;birth control pills<\/strong><\/li><li><strong>cimetidine<\/strong>&nbsp;(to&nbsp;inhibit&nbsp;acid production in the stomach).<\/li><\/ul>\n\n\n\n<p>Some medicines may increase the effects of Budenofalk&nbsp;granules&nbsp;and your doctor may want to monitor you closely if you are taking these medicines (eg some medicines for HIV: ritonavir, cobicistat).<br><\/p>\n\n\n\n<p>If you are taking&nbsp;<strong>cholestyramine<\/strong>&nbsp;(for&nbsp;hypercholesterolemia&nbsp;and also to treat diarrhea) or&nbsp;<strong>antacids<\/strong>&nbsp;(for digestion) in addition to Budenofalk&nbsp;granules&nbsp;, take these medicines&nbsp;<strong>at least 2 hours apart<\/strong>&nbsp;.<br><\/p>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;may affect the results of any tests performed by your doctor or hospital.&nbsp;Tell your doctor that you are taking Budenofalk&nbsp;granules&nbsp;before any test.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Budenofalk granules with food and drink<\/h2>\n\n\n\n<p>You should&nbsp;<strong>not<\/strong>&nbsp;drink&nbsp;<strong>grapefruit juice<\/strong>&nbsp;while taking this medicine as it may alter the effects of the medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Only take Budenofalk&nbsp;granules&nbsp;during pregnancy if your doctor tells you to.<br><\/p>\n\n\n\n<p>Budesonide in small amounts is converted into breast milk.&nbsp;If you are breast-feeding, only take Budenofalk&nbsp;granules&nbsp;if&nbsp;your&nbsp;doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;are not expected to affect your ability to drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Budenofalk granules contain sucrose, lactose and sorbitol<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicine contains 900 mg sorbitol per&nbsp;sachet&nbsp;.&nbsp;Sorbitol is a source of fructose.&nbsp;If you have been&nbsp;told by your doctor that you have an&nbsp;intolerance to&nbsp;some sugars, or if you have been diagnosed with&nbsp;hereditary&nbsp;fructose intolerance&nbsp;, a rare, inherited disease that prevents you from breaking down fructose, talk to your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Budenofalk granules<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;is<\/strong><br><\/p>\n\n\n\n<p><strong>Crohn&#8217;s disease&nbsp;and&nbsp;collagen&nbsp;colitis<\/strong><\/p>\n\n\n\n<p><strong>Adults (over 18 years)<\/strong><\/p>\n\n\n\n<p>Take a&nbsp;sachet&nbsp;in the morning if you have not received any other information from your doctor.<br><\/p>\n\n\n\n<p><strong>Use for children and adolescents<\/strong><\/p>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;should NOT be used by&nbsp;<strong>children<\/strong>&nbsp;under 18 years of age.<br><\/p>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;should only be taken by mouth.<\/p>\n\n\n\n<p>You should take Budenofalk&nbsp;granules&nbsp;about \u00bd hour before breakfast.&nbsp;Put&nbsp;granulesdirectly on the tongue and swallow it with a glass of water.&nbsp;<strong>Do not chew<\/strong>&nbsp;on&nbsp;granulesas it may not work properly.<br><\/p>\n\n\n\n<p><strong>Duration of treatment<\/strong><\/p>\n\n\n\n<p>Your treatment should last for about 8 weeks.<br><\/p>\n\n\n\n<p>Your doctor will decide how long you should continue to take the medicine, depending on your condition.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Budenofalk granules<\/h2>\n\n\n\n<p>If you miss a&nbsp;dose&nbsp;, just continue the treatment with the prescribed&nbsp;dose&nbsp;.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Budenofalk granules<\/h2>\n\n\n\n<p>Talk to your doctor if you want to stop or stop treatment earlier.&nbsp;It is important that you do not stop taking the medicine abruptly as it may make you ill.&nbsp;Keep taking this medicine until your doctor tells you to stop, even if you start to feel better.<br><\/p>\n\n\n\n<p>Your doctor will probably want to reduce the&nbsp;dose&nbsp;one&nbsp;at a&nbsp;time&nbsp;, from one&nbsp;sachetevery day to one&nbsp;sachet&nbsp;every other day for at least 2 weeks.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>If you get any of the following symptoms after taking this medicine, contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection<\/li><li>headache<\/li><li>behavioral changes such as depression, irritation,&nbsp;euphoria&nbsp;, restlessness, anxiety and aggression.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have also been reported:<br><\/p>\n\n\n\n<p><strong>Common&nbsp;<\/strong><em>(may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cushing&#8217;s syndrome &#8211; e.g.&nbsp;with rounded face, weight gain, decreased glucose tolerance, high blood sugar, high&nbsp;blood pressure&nbsp;, fluid retention in the body (eg swollen legs), increased excretion of&nbsp;potassium&nbsp;(&nbsp;hypokalaemia&nbsp;), irregular menstruation in women, unwanted body hair in women,&nbsp;impotence&nbsp;, abnormal laboratory results ( impaired adrenal function), red streaks on the skin (stretch marks),&nbsp;acne<\/li><li>stomach upset, irritated stomach (&nbsp;dyspepsia&nbsp;), abdominal pain<\/li><li>increased risk of infection<\/li><li>muscle and joint pain, muscle weakness, muscle twitching<\/li><li>bone loss (&nbsp;osteoporosis&nbsp;)<\/li><li>headache<\/li><li>mood swings, e.g.&nbsp;depression, irritation and&nbsp;euphoria<\/li><li>rash due to&nbsp;hypersensitivity reactions&nbsp;, red spots caused by bleeding in the skin, delayed wound healing, local skin reactions, e.g.&nbsp;contact dermatitis<br><\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;<\/strong><em>(may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ulcers in the stomach or small intestine<\/li><li>restlessness with increased physical activity, anxiety<\/li><\/ul>\n\n\n\n<p><strong>Rare (&nbsp;<\/strong><em>may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dimsyn<\/li><li>inflammation&nbsp;of the pancreas<\/li><li>bone loss caused by poor blood circulation<\/li><li>aggression<\/li><li>bruises<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;<\/strong><em>(may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stunted growth in children<\/li><li>constipation<\/li><li>increased pressure in the brain, possibly with increased pressure in the eyes (swelling of the optic nerve papilla) in adolescents<\/li><li>increased risk of blood clots,&nbsp;inflammation&nbsp;of the blood vessels (may occur after long-term cortisone treatment)<\/li><li>fatigue, general malaise<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are typical when treated with&nbsp;steroids&nbsp;and most can also be expected when treated with other&nbsp;steroids&nbsp;.&nbsp;They may occur depending on your&nbsp;dose, the duration of treatment, whether you have received or are being treated with other cortisone preparations, and your individual sensitivity.&nbsp;If you have been treated with a stronger cortisone preparation before starting treatment with Budenofalk granules, your symptoms may return when the medicine is changed.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Budenofalk granules<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and sachet.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The&nbsp;<strong>active substance<\/strong>&nbsp;is budesonide.&nbsp;Each&nbsp;sachet of&nbsp;enterogranulate&nbsp;contains 9 mg budesonide<\/p>\n\n\n\n<p><strong>The other ingredients<\/strong>&nbsp;are ammonio methacrylate copolymer (type A) (Eudragit RL), ammonio methacrylate copolymer (type B) (Eudragit RS), anhydrous citric acid,&nbsp;lactose monohydrate&nbsp;, lemon flavor, magnesium stearate, methacrylic acid-methyl methacrylate copolymer (1: 1) 100 methyl methacrylate copolymer polymer (1: 2) (Eudragit S 100), povidone K25, sucralose, sugar spheres (consisting of sucrose and maize starch), sorbitol (E420), talc, triethyl citrate, xanthan gum.&nbsp;(See section 2 for more information on&nbsp;lactose&nbsp;, sucrose and sorbitol).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;are white to off-white&nbsp;enterogranules&nbsp;and white to light yellow powder with lemon flavor in a&nbsp;sachet&nbsp;.<br><\/p>\n\n\n\n<p>Budenofalk&nbsp;granules&nbsp;are available in pack sizes of 15, 20, 30, 50 and 60 sachets.&nbsp;Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Dr.&nbsp;Falk Pharma GmbH<\/p>\n\n\n\n<p>Leinenweberstr.&nbsp;5<\/p>\n\n\n\n<p>79108 Freiburg<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>Information provided by<\/strong>&nbsp;:<\/p>\n\n\n\n<p>Vifor Pharma Nordiska AB&nbsp;<br>Gustav III: s Boulevard 46<\/p>\n\n\n\n<p>169 73 Solna<\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized by the Member States of the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Finland, Germany, Greece, Hungary, Ireland, Luxembourg, Netherlands, Norway, Portugal, Romania, Slovakia, Slovenia, , United Kingdom: Budenofalk<\/p>\n\n\n\n<p>Austria: Budo-San<\/p>\n\n\n\n<p>France: MIKICORT<\/p>\n\n\n\n<p>Italy: Intesticort mono<\/p>\n\n\n\n<p>Spain: Intestifalk<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Budenofalk granules contain the active substance budesonide, a type of topical steroid used to treat chronic inflammatory bowel disease.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8285,8287,4130,4132,8289,6576,8288,8284,8286,4131],"class_list":["post-6279","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-budenofalk","tag-budenofalk-side-effects","tag-budesonide","tag-budesonide-side-effects","tag-side-effects-of-budenofalk","tag-side-effects-of-budesonide","tag-what-budenofalk-is-used-for","tag-what-budesonide-is-used-for","tag-what-is-budenofalk","tag-what-is-budesonide"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6279"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6279\/revisions"}],"predecessor-version":[{"id":11786,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6279\/revisions\/11786"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6279"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6279"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}