{"id":6258,"date":"2021-01-04T14:51:57","date_gmt":"2021-01-04T14:51:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6258"},"modified":"2021-06-26T07:45:08","modified_gmt":"2021-06-26T07:45:08","slug":"brinzolamide-timolol-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/brinzolamide-timolol-accord\/","title":{"rendered":"Brinzolamide \/ Timolol Accord &#8211; Timolol uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n10 mg \/ ml + 5 mg \/ ml&nbsp;eye drops&nbsp;, suspension&nbsp;<br>brinzolamide \/ <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/\">timolol<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Brinzolamide \/ Timolol Accord is and what it is used for<\/h2>\n\n\n\n<p>Brinzolamide \/ Timolol Accord contains two ingredients, brinzolamide, and&nbsp;timolol, which together lower the pressure in the eye.<br><\/p>\n\n\n\n<p>Brinzolamide \/ Timolol Accord is used to treat high pressure in the eyes, also called&nbsp;glaucoma&nbsp;or&nbsp;ocular&nbsp;hypertension, in adult patients over 18 years of age and in whom it is not possible to effectively control the high pressure in the eyes with just one drug.<br><\/p>\n\n\n\n<p>Brinzolamide and&nbsp;timolol contained&nbsp;in Brinzolamide \/ Timolol Accord may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to brinzolamide, medicines called&nbsp;sulphonamides&nbsp;(for example medicines used to treat&nbsp;diabetes,&nbsp;infections,&nbsp;and also&nbsp;diuretics&nbsp;),&nbsp;timolol,&nbsp;beta-blockers&nbsp;(medicines used to lower&nbsp;blood pressure&nbsp;or to treat heart disease), or anything else ingredient of this medicinal product (listed in section 6)<\/li><li>if you currently have or have ever had lung diseases such as&nbsp;asthma, severe long-term obstructive&nbsp;bronchitis&nbsp;(severe lung disease that may cause wheezing, difficulty breathing, and\/or persistent cough), or other types of breathing problems<\/li><li>if you have severe hay fever<\/li><li>if you have a low&nbsp;heart rate,&nbsp;heart failure,&nbsp;or diseases that affect the heart rhythm (irregular heartbeat)<\/li><li>if you have too acidic blood (a condition called hyperchloraemic acidosis)<\/li><li>if you have severe kidney problems<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Use only Brinzolamide \/ Timolol Accord as&nbsp;eye drops.<br><\/p>\n\n\n\n<p>If there are any signs of a serious reaction or&nbsp;hypersensitivity reaction, stop using the medicine and talk to your doctor.<br><\/p>\n\n\n\n<p>Talk to your doctor or pharmacist before using Brinzolamide \/ Timolol Accord if you have or have ever had<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>coronary heart disease (symptoms may include pain or tightness in the chest, shortness of breath, or suffocation),&nbsp;heart failure, low blood pressure<\/li><li>heart rate disorders such as&nbsp;slow heartbeat<\/li><li>respiratory problems,&nbsp;asthma,&nbsp;or&nbsp;chronic&nbsp;obstructive pulmonary disease<\/li><li>disease with impaired blood circulation (eg&nbsp;Raynaud&#8217;s disease&nbsp;or Raynaud&#8217;s syndrome)<\/li><li>diabetes&nbsp;because&nbsp;timolol&nbsp;can mask the signs and symptoms of low blood sugar<\/li><li>overactive&nbsp;thyroid gland&nbsp;as&nbsp;timolol&nbsp;can mask signs and symptoms of thyroid disease<\/li><li>muscle weakness (myasthenia gravis)<\/li><li>Tell your doctor before surgery that you are using Brinzolamide \/ Timolol Accord as&nbsp;timolol&nbsp;may alter the effects of certain medicines during anesthesia<\/li><li>if you have had atopy (a tendency to have an&nbsp;allergic reaction&nbsp;) and severe allergic reactions, you may be more susceptible to having an&nbsp;allergic reaction&nbsp;while using Brinzolamide \/ Timolol Accord, and treatment with&nbsp;adrenaline&nbsp;may not be as effective in treating an allergic reaction;&nbsp;therefore, tell your doctor or nurse that you are using Brinzolamide \/ Timolol Accord when you receive any other treatment<\/li><li>if you have liver problems<\/li><li>if you have dry eyes or problems with the cornea (&nbsp;the cornea&nbsp;)<\/li><li>if you have kidney problems.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Brinzolamide \/ Timolol Accord is not recommended for children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Brinzolamide \/ Timolol Accord can interact with other medications you are using, including other&nbsp;eye drops&nbsp;for the treatment of&nbsp;glaucoma&nbsp;(&nbsp;glaucoma&nbsp;).&nbsp;Tell your doctor if you are taking or plan to take medicines to lower your&nbsp;blood pressure, such as para sympathomimetics and guanethidine, or other heart medicines that contain&nbsp;quinidine&nbsp;(used to treat heart conditions and certain types of&nbsp;malaria&nbsp;),&nbsp;amiodarone other medicines to treat heart rhythm disorders and&nbsp;glycosides&nbsp;to treat&nbsp;heart failure.&nbsp;Also tell your doctor if you are taking or intend to take medicines to treat&nbsp;diabetes&nbsp;or&nbsp;stomach ulcers, antifungals, antivirals or&nbsp;antibiotics&nbsp;or antidepressants such as&nbsp;fluoxetine&nbsp;and paroxetine.<br><\/p>\n\n\n\n<p>If you are taking another&nbsp;carbohydrate inhibitor&nbsp;(acetazolamide or <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/torzkom\/\">dorzolamide<\/a>), talk to your doctor.&nbsp;Increases in pupil size during concomitant use of Brinzolamide \/ Timolol Accord and&nbsp;adrenaline&nbsp;(&nbsp;epinephrine&nbsp;) have been reported sporadically.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>You should not use Brinzolamide \/ Timolol Accord if you are pregnant or likely to become pregnant unless your doctor considers it necessary.&nbsp;Talk to your doctor before using Brinzolamide \/ Timolol Accord.<br><\/p>\n\n\n\n<p>Do not use Brinzolamide \/ Timolol Accord if you are breast-feeding,&nbsp;timolol&nbsp;may pass into breast milk.&nbsp;Consult a doctor before taking any medicine while breast-feeding<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p><strong>Do not drive or use any tools or machines until the vision is clear.&nbsp;<\/strong>You may experience blurred vision for a while just after using Brinzolamide \/ Timolol Accord.<br><\/p>\n\n\n\n<p>One of the active substances may affect the ability of elderly patients to perform tasks that require mental alertness and\/or physical coordination.&nbsp;If you are affected, you should be careful when driving or using machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Brinzolamide \/ Timolol Accord contains excipients<\/h2>\n\n\n\n<p>This medicine contains 0.0033 mg of benzalkonium chloride in each drop corresponding to 0.01% or 0.1 mg\/ml.<br><\/p>\n\n\n\n<p>Benzalkonium chloride is a&nbsp;preservative&nbsp;in Brinzolamide \/ Timolol Accord that can be absorbed by soft contact lenses and can discolor the contact lenses.&nbsp;Remove contact lenses before using the medicine and wait at least 15 minutes before re-inserting the contact lenses.<br><\/p>\n\n\n\n<p>Benzalkonium chloride can be irritating to the eyes, especially if you have dry eyes or problems with the cornea (the clear membrane at the front of the eye).&nbsp;If you experience irritation, tingling, or pain in the eye after using the medicine, consult a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>If you switch from other&nbsp;eye drops&nbsp;used to treat&nbsp;glaucoma&nbsp;and switch to Brinzolamide \/ Timolol Accord, stop using the other medicine and start using Brinzolamide \/ Timolol Accord the next day.&nbsp;If you are not sure, ask your doctor or pharmacist.<br><\/p>\n\n\n\n<p>To prevent the tip and&nbsp;suspension of the&nbsp;dropper&nbsp;from contaminating, make sure that you do not touch the eyelids, surrounding areas, or other surfaces with the tip of the dropper.&nbsp;Keep the bottle tightly closed when not in use.<br><\/p>\n\n\n\n<p>The following measures are helpful in limiting the amount of drug that enters the bloodstream after the application of eye drops:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Close your eyes while gently pressing the inner corner of your eye with your finger for at least 2 minutes.<\/li><\/ul>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one drop in the affected eye (s) twice daily.<\/p>\n\n\n\n<p>Only use Brinzolamide \/ Timolol Accord in both eyes if your doctor prescribes it.&nbsp;Use Brinzolamide \/ Timolol Accord for as long as your doctor prescribes it.<br><\/p>\n\n\n\n<p>To use the eye drops:<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190715000014#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/06cc2da3-bab3-4364-ad0a-293d4faeb5bb\" alt=\"How to use the eye drops\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Get the bottle and a mirror.<\/li><li>Wash your hands.<\/li><li>Shake the bottle carefully before use.<\/li><li>Unscrew the cap on the bottle.&nbsp;If the safety collar is loose after removing the hat, remove the collar before using the product.<\/li><li>Hold the bottle upside down between your thumb and forefinger.<\/li><li>Tilt your head back.&nbsp;Pull the eyelid down with a clean finger, so that a pocket is formed between the eyelid and the eye.&nbsp;The drop should end up in the pocket (figure 1).<\/li><li>Move the tip of the bottle close to the eye.&nbsp;Use the mirror if it facilitates.<\/li><li>Do not touch the eye or eyelid, surrounding areas, or other surfaces with the bottle tip.&nbsp;This can contaminate the droplets.<\/li><li>Squeeze a drop into the pocket formed between the eye and the eyelid (figure 2)<\/li><li>After using Brinzolamide \/ Timolol Accord, press lightly with a finger against the corner of your eye at the nose for at least 1 minute.&nbsp;This prevents Brinzolamide \/ Timolol Accord from entering the rest of the body (Figure 3).<\/li><li>If you use drops in both eyes, repeat the above steps in the other eye.<\/li><li>Screw the cap onto the bottle firmly immediately after use.<\/li><li>Use one bottle before opening the next.<\/li><\/ul>\n\n\n\n<p>If the drop misses the eye, try again.<br><\/p>\n\n\n\n<p>If you use other&nbsp;eye drops&nbsp;or ointments, wait at least 5 minutes between each medicine.&nbsp;Eye ointments should be used last.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Brinzolamide \/ Timolol Accord than you should &nbsp;<\/h2>\n\n\n\n<p><strong>If you use more Brinzolamide \/ Timolol Accord<\/strong>&nbsp;then you should rinse your eyes with lukewarm water.&nbsp;Do not drip in more drops until it is time for your next&nbsp;dose.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<p><strong>If you forget to use Brinzolamide \/ Timolol Accord<\/strong>, continue with the next&nbsp;dose as usual.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Do not use more than one drop in the affected eye (s) twice daily.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<p><strong>If you stop using Brinzolamide \/ Timolol Accord<\/strong>&nbsp;without talking to your doctor, the pressure in your eye will not be checked, which could lead to vision loss.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop&nbsp;using&nbsp;this&nbsp;medicine&nbsp;and&nbsp;contact your doctor immediately<\/strong>&nbsp;if you get a rash, a severe skin reaction, or severe&nbsp;redness&nbsp;and&nbsp;itching&nbsp;in the eye.&nbsp;This may be a sign of an&nbsp;allergic reaction&nbsp;(frequency is unknown).<br><\/p>\n\n\n\n<p>You can usually continue to use the drops unless the&nbsp;side effects&nbsp;are severe<strong>.&nbsp;<\/strong>If you are worried, talk to your doctor or pharmacist.&nbsp;Do not stop using Brinzolamide \/ Timolol Accord without talking to your doctor first.<br><\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Effects&nbsp;in the eye:&nbsp;<\/strong>Inflammation&nbsp;of the surface of the eye, blurred vision, signs, and symptoms of eye irritation (eg burning sensation, tingling,&nbsp;itching, tearing,&nbsp;redness&nbsp;), eye pain.<\/li><li><strong>General&nbsp;side effects:<\/strong>&nbsp;Slower&nbsp;heart rate, taste changes.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Effects&nbsp;in the eye:&nbsp;<\/strong>Erosion&nbsp;of the cornea (damage to the anterior layer of the eyeball),&nbsp;inflammation&nbsp;of the surface of the eye with surface damage,&nbsp;inflammation&nbsp;inside the eye, staining of the cornea, abnormal sensation in the eyes, discharge from the eye, dry eyes, tired eyes, itchy eyes, red eyes, eyelid redness.<\/li><li>General&nbsp;side effects:&nbsp;Decreased&nbsp;white blood cell count, decreased&nbsp;blood pressure, cough, blood in the urine, weakness in the body.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Effects&nbsp;<\/strong><strong>in the eye:<\/strong>&nbsp;corneal problems, photosensitivity, increased tear production, crusting on the eyelid<\/li><li><strong>Common&nbsp;<\/strong><strong>side effects:<\/strong>&nbsp;difficulty sleeping, sore throat, runny nose<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in the unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Effects&nbsp;in the eye:<\/strong>&nbsp;Eye allergy, visual disturbance, damage to the&nbsp;optic nerve, increased pressure in the eye, deposits on the surface of the eye, decreased sensitivity in the eye,&nbsp;inflammation&nbsp;or&nbsp;infection&nbsp;in the conjunctiva (whites of the eyes), abnormal, double or impaired vision, increased&nbsp;pigmentation&nbsp;in the eye, growth on the surface of the eye, swollen eyes, photosensitivity, decreased growth of&nbsp;eyelashes&nbsp;or decreased number of&nbsp;eyelashes&nbsp;, drooping upper eyelids (keeps the eye half-closed),&nbsp;inflammation&nbsp;of the eyelids and eyelid glands,&nbsp;inflammation the cornea and loosening of the layer under the retina that contains blood vessels after filtration surgery, which can cause visual disturbances, decreased sensitivity of the cornea.<\/li><li><strong>Heart&nbsp;and&nbsp;blood circulation:<\/strong>&nbsp;Altered rhythm or rate of the heartbeat, slow&nbsp;heart rate, palpitations, a type of heart rhythm, abnormal increase of&nbsp;pulse&nbsp;a, chest pain, cardiac dysfunction, myocardial infarction, increased&nbsp;blood pressure, decreased blood supply to the brain,&nbsp;stroke,&nbsp;edema&nbsp;(fluid retention),&nbsp;chronic heart failure&nbsp;(heart disease with shortness of breath and swelling of the feet and legs due to fluid retention), swollen&nbsp;extremities, low&nbsp;blood pressure&nbsp;, discoloration of fingers, toes and sometimes other parts of the body (Raynaud&#8217;s phenomenon), cold hands and feet.<\/li><li><strong>Lungs \/ Respiratory tract:<\/strong>&nbsp;Contraction of the airways in the lungs (especially in patients with pre-existing disease), shortness of breath or shortness of breath, cold symptoms, chest tightness, sinusitis, sneezing, nasal congestion, dry nose, nosebleeds,&nbsp;asthma, irritation of the throat.<\/li><li><strong>Nervous system&nbsp;and&nbsp;general&nbsp;disorders:<\/strong>&nbsp;Depression, nightmares, memory loss, headache, nervousness, irritation, fatigue, tremors, abnormal sensation, fainting, dizziness, drowsiness, general or severe weakness, unusual sensations such as.&nbsp;tingling in the skin, hallucination.<\/li><li><strong>Gastrointestinal disorders:<\/strong>&nbsp;Nausea, vomiting, diarrhea, flatulence, or uncomfortable feeling in the abdomen, sore throat, dry or abnormal sensation in the mouth, stomach upset, stomach pain.<\/li><li><strong>Blood:<\/strong>&nbsp;Abnormal liver function values, increased levels of chlorine in the blood, or decreased number of&nbsp;red blood cells&nbsp;during blood tests.<\/li><li><strong>Allergy:<\/strong>&nbsp;Increased allergic symptoms, generalized allergic reactions, including swelling under the skin that may occur in places such as.&nbsp;face arms and legs and may obstruct the airways which may cause difficulty in swallowing or breathing, hives, limited and generalized rash,&nbsp;itching, severe, sudden life-threatening&nbsp;allergic reaction.<\/li><li><strong>Ears:<\/strong>&nbsp;Ringing in the ears, feeling of rotation or dizziness<\/li><li><strong>Skin:<\/strong>&nbsp;Rash, redness or&nbsp;inflammation&nbsp;, abnormal or diminished sensation in the skin, hair loss, rash with white silvery appearance (psoriasis-like rash), or worsening of&nbsp;psoriasis.<\/li><li><strong>Muscles:<\/strong>&nbsp;General back, joint, or muscle pain not caused by exercise, muscle cramps, pain in the&nbsp;extremities, muscle weakness\/muscle fatigue, increased signs and symptoms of myasthenia gravis (muscle disorder).<\/li><li><strong>Kidneys:<\/strong>&nbsp;Kidney pain such as back pain, frequent urination.<\/li><li><strong>Reproduction:<\/strong>&nbsp;Sexual&nbsp;dysfunction, decreased&nbsp;libido, sexual difficulties in men.<\/li><li><strong>Metabolism:<\/strong>&nbsp;Low blood sugar levels.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Brinzolamide \/ Timolol Accord<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>You must discard the bottle 4 weeks after opening it, to prevent&nbsp;infection, and use a new bottle.&nbsp;Write down the date when you opened it on the intended space on the bottle and carton.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are brinzolamide and&nbsp;timolol.&nbsp;One milliliter of&nbsp;suspensioncontains 10 mg brinzolamide and timolol maleate equivalent to 5 mg&nbsp;timolol.<\/li><li>The other ingredients are benzalkonium chloride (see section 2, \u201cBrinzolamide \/ Timolol Accord contains benzalkonium chloride\u201d), carbomer, disodium edetate, mannitol (E421), purified water, sodium chloride,&nbsp;hydrochloric acid,&nbsp;and\/or sodium hydroxide.<\/li><\/ul>\n\n\n\n<p>Small amounts of&nbsp;hydrochloric acid&nbsp;and\/or sodium hydroxide are added to keep the acidity (&nbsp;pH&nbsp;) normal.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Brinzolamide \/ Timolol Accord is a liquid (white to off-white even&nbsp;suspension&nbsp;), supplied in a carton containing a 5 ml bottle of low-density polyethylene (LDPE) with a drop insert of LDPE and one with a lid of high-density polyethylene (HDPE) containing 5 ml of&nbsp;suspension.<br><\/p>\n\n\n\n<p>Cartons containing 1, 3, or 6 bottles.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 kV Utrecht<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Lusomedicamenta Sociedade T\u00e9cnica Pharmac\u00eautica SA<\/p>\n\n\n\n<p>Rua Norberto De Oliveira 1-5<\/p>\n\n\n\n<p>Povoa De Santo Adriao<\/p>\n\n\n\n<p>Lisbon, 2620-111<\/p>\n\n\n\n<p>Portugal<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Brinzolamide \/ Timolol Accord contains two ingredients, brinzolamide, and timolol, which together lower the pressure in the eye.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8370,8390,5029,8386,8389,5248,8371,5030,8387,8388,8380],"class_list":["post-6258","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-brinzolamide","tag-brinzolamide-eye-dropswhat-brinzolamide-is-used-for","tag-timolol","tag-timolol-accord","tag-timolol-accord-eye-drops","tag-timolol-eye-drops","tag-what-is-brinzolamide","tag-what-is-timolol","tag-what-is-timolol-accord","tag-what-timolol-accord-is-used-for","tag-what-timolol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6258","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6258"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6258\/revisions"}],"predecessor-version":[{"id":11829,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6258\/revisions\/11829"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}