{"id":6221,"date":"2021-01-03T15:02:55","date_gmt":"2021-01-03T15:02:55","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6221"},"modified":"2021-06-28T06:24:06","modified_gmt":"2021-06-28T06:24:06","slug":"brilique","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/brilique\/","title":{"rendered":"Brilique &#8211; Tikagrelor uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n60 mg&nbsp;film-coated tablets&nbsp;<br>tikagrelor<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Brilique is and what it is used for<\/h2>\n\n\n\n<p><strong>What Brilique is<\/strong><\/p>\n\n\n\n<p>Brilique contains an active substance called tikagrelor.&nbsp;It belongs to a group of medicines called antiplatelet drugs.<br><\/p>\n\n\n\n<p><strong>What Brilique is used for<\/strong><\/p>\n\n\n\n<p>Brilique, in combination with&nbsp;acetylsalicylic acid&nbsp;(another antiplatelet drug), should only be used by adults.&nbsp;You have been given this medicine because you have had:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a heart attack, over a year ago.<\/li><\/ul>\n\n\n\n<p>It reduces the risk of you having another heart attack or&nbsp;stroke&nbsp;or dying from cardiovascular disease.<br><\/p>\n\n\n\n<p><strong>How Brilique works<\/strong><\/p>\n\n\n\n<p>Brilique affects cells called &#8220;platelets&#8221; (or&nbsp;platelets&nbsp;).&nbsp;It is very small blood cells that help stop bleeding.&nbsp;They do this by clumping together so that they can plug the small holes in blood vessels that have been damaged.<br><\/p>\n\n\n\n<p>But platelets can also form blood clots inside diseased blood vessels in the heart and brain.&nbsp;It can be very dangerous because<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the blood clot can turn off the blood flow completely;&nbsp;which can cause a heart attack (heart attack) or a&nbsp;stroke&nbsp;, or<\/li><li>the blood clot can partially block the blood vessels to the heart;&nbsp;then the blood flow to the heart becomes less.&nbsp;It can cause chest pain that comes and goes (so-called &#8220;unstable angina&#8221;).<\/li><\/ul>\n\n\n\n<p>Brilique helps so that the platelets do not clot.&nbsp;This reduces the risk of a blood clot forming which can reduce blood flow.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Brilique<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Brilique<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ticagrelor or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are bleeding right now.<\/li><li>if you have had a&nbsp;stroke&nbsp;where the cause was a brain haemorrhage.<\/li><li>if you have severe liver disease.<\/li><li>if you are taking any of the following medicines:<ul><li>ketoconazole&nbsp;(used to treat fungal infections)<\/li><li>clarithromycin (used against bacterial infections)<\/li><li>nefazodone (an antidepressant drug)<\/li><li>ritonavir and atazanavir (used for&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;and&nbsp;AIDS&nbsp;).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Do not use Brilique if any of the above apply to you.&nbsp;If you have any further questions, ask your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Brilique<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have an increased risk of bleeding due to<ul><li>that you have recently been seriously injured<\/li><li>that you have recently had surgery (including procedures involving the teeth, ask your dentist about this)<\/li><li>that you have a disease that affects blood coagulation<\/li><li>that you have recently had bleeding from the stomach or intestines (for example&nbsp;stomach ulcers&nbsp;or colon polyps)<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are going to have surgery (including dental procedures) at any time while you are taking Brilique.&nbsp;The reason is the increased risk of bleeding.&nbsp;Your doctor may want you to stop taking this medicine 5 days before the operation.<\/li><li>if your&nbsp;heart rate&nbsp;is abnormally low (usually below 60 beats per minute) and you have not already had a small device implanted that makes the heart beat at the right pace (a pacemaker).<\/li><li>if you have&nbsp;asthma&nbsp;or other lung problems or breathing problems.<\/li><li>if you have had liver problems or have previously had a disease that may have affected your liver.<\/li><li>if a blood test has shown that you have more&nbsp;uric acid&nbsp;in your blood than usual.<\/li><\/ul>\n\n\n\n<p>If any of the above applies to you (or you are not sure), talk to your doctor or pharmacist before taking this medicine.<br><\/p>\n\n\n\n<p>If you take both Brilique and heparin:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may need to take a blood test for a diagnostic test if he \/ she suspects an unusual platelet disease caused by&nbsp;heparin&nbsp;.&nbsp;It is important that you tell your doctor that you are taking both Brilique and&nbsp;heparin&nbsp;, as Brilique may affect the diagnostic test.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Brilique is not recommended for children and adolescents under 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Brilique<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.&nbsp;The reason is that Brilique can affect how certain medicines work and certain medicines can affect Brilique.<br><\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>more than 40 mg daily of either&nbsp;simvastatin&nbsp;or lovastatin (medicines used to treat high cholesterol)<\/li><li>rifampicin (an&nbsp;antibiotic&nbsp;)<\/li><li>phenytoin&nbsp;, carbamazepine and phenobarbital (used to treat seizures)<\/li><li>digoxin&nbsp;(used for&nbsp;heart failure&nbsp;)<\/li><li>cyclosporine (used to reduce the body&#8217;s defense mechanisms)<\/li><li>quinidine&nbsp;and&nbsp;diltiazem&nbsp;(used to treat abnormal heart rhythms)<\/li><li>beta-blockers&nbsp;and verapamil (used to treat high&nbsp;blood pressure&nbsp;)<\/li><li>morphine and other&nbsp;opioids&nbsp;(used to treat severe pain).<\/li><\/ul>\n\n\n\n<p><br>In particular, tell your doctor or pharmacist if you are taking any of the following medicines that increase the risk of bleeding:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>&#8220;Oral anticoagulants&#8221; &#8211; often called &#8220;blood thinners&#8221; and include&nbsp;warfarin&nbsp;.<\/li><li>non-steroidal anti-inflammatory drugs (often abbreviated&nbsp;NSAIDs&nbsp;), which are often used as painkillers, such as&nbsp;ibuprofen&nbsp;and&nbsp;naproxen&nbsp;.<\/li><li>selective serotonin reuptake inhibitors (&nbsp;SSRIs&nbsp;) used as antidepressants, such as&nbsp;paroxetine&nbsp;,&nbsp;sertraline&nbsp;and&nbsp;citalopram<\/li><li>other drugs&nbsp;ketoconazole&nbsp;(used against fungal infections), clarithromycin (used for bacterial infections), nefazodone (an antidepressant), ritonavir and atazanavir (used for&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;and&nbsp;AIDS&nbsp;), cisapride (used for heartburn), ergot alkaloids (used against&nbsp;migraine&nbsp;and headache).<\/li><\/ul>\n\n\n\n<p><br>Because you are taking Brilique you may have an increased risk of bleeding.&nbsp;Therefore, you should tell your doctor that you are taking Brilique if he or she gives you&nbsp;fibrinolytics&nbsp;(often called &#8216;blood clotting agents&#8217;), such as streptokinase or alteplas.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>The use of Brilique is not recommended if you are pregnant or could become pregnant.&nbsp;Women should use appropriate contraception to avoid pregnancy while taking this medicine.<br><\/p>\n\n\n\n<p>Before taking this medicine, talk to your doctor if you are breast-feeding.&nbsp;Your doctor will discuss the benefits and risks of taking Brilique with you during this time.<br><\/p>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>It is unlikely that Brilique will affect your ability to drive or use machines.&nbsp;If you feel dizzy or confused when taking this medicine, be careful when driving or using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Sodium content<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per dose unit, ie essentially &#8216;&nbsp;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Brilique<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>This is how much you should take<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The usual&nbsp;dose&nbsp;is one 60 mg tablet twice a day.&nbsp;Keep taking Brilique for as long as your doctor tells you to.<\/li><li>Take this medicine at about the same time each day (for example, one tablet in the morning and one in the evening).<\/li><\/ul>\n\n\n\n<p><strong>Taking Brilique with other medicines to prevent blood clots<\/strong><\/p>\n\n\n\n<p>Usually your doctor will also tell you to take&nbsp;acetylsalicylic acid&nbsp;.&nbsp;It is a substance found in many medicines used to prevent blood clots.&nbsp;Your doctor will tell you how much to take (usually 75-150 mg a day).<br><\/p>\n\n\n\n<p><strong>How to take Brilique<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You can take the tablet with or without food.<\/li><li>You can check when you last took a Brilique tablet by looking at the blister map.&nbsp;There is a sun (for the morning) and a moon (for the evening).&nbsp;This way you can see if you have taken a&nbsp;dose&nbsp;or not.<\/li><\/ul>\n\n\n\n<p><strong>If you have difficulty swallowing the tablet<\/strong><\/p>\n\n\n\n<p>If you have difficulty swallowing the tablet, you can crush it and mix it with water as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Crush the tablet to a fine powder<\/li><li>Pour the powder into half a glass of water<\/li><li>Stir and drink immediately<\/li><li>To make sure there is no medicine left, rinse the empty glass with another half glass of water and drink it<\/li><\/ul>\n\n\n\n<p>If you are hospitalized, you can get this tablet, mixed with a little water, given with a tube through your nose (nasogastric tube) into your stomach.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Brilique than you should<\/h2>\n\n\n\n<p>If you take more Brilique than you should, contact a doctor or go to the hospital immediately.&nbsp;Bring the medicine pack.&nbsp;You may have an increased risk of bleeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Brilique<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, just take the next&nbsp;dose&nbsp;as usual.<\/li><li>Do not take a double&nbsp;dose&nbsp;(two&nbsp;doses&nbsp;at the same time) to compensate for a missed&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Brilique<\/h2>\n\n\n\n<p>Do not stop taking Brilique without talking to your doctor.&nbsp;Take this medicine regularly and as long as your doctor continues to prescribe it.&nbsp;If you stop taking Brilique, it may increase the risk of you having another heart attack or&nbsp;stroke&nbsp;or dying from cardiovascular disease.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;The following&nbsp;side effects&nbsp;may occur with this medicine:<br><\/p>\n\n\n\n<p>Brilique affects blood coagulation, so most&nbsp;side effects&nbsp;have to do with bleeding.&nbsp;Bleeding can occur anywhere in the body.&nbsp;Some bleeding is common (such as bruising and nosebleeds).&nbsp;Severe bleeding is less common, but can be life-threatening.<br><\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you notice any of the following &#8211; you may needurgent&nbsp;medical attention:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Bleeding in the brain or on the inside of the skull is a less common side effect and can be a sign of a&nbsp;stroke&nbsp;such as:<\/strong><ul><li>sudden numbness or weakness in the arm, leg or face, especially if it only affects one side of the body<\/li><li>sudden confusion, difficulty speaking or understanding others<\/li><li>sudden difficulty walking or impaired balance or coordination<\/li><li>sudden dizziness or sudden severe headache for no known reason<\/li><\/ul><\/li><li><strong>Signs of bleeding such as:<\/strong><ul><li>severe bleeding or bleeding over which you have no control<\/li><li>unexpected bleeding or bleeding that lasts a long time<\/li><li>pink, red or brown urine<\/li><li>vomiting of red blood or if the vomit looks like coffee grounds<\/li><li>red or black stools (tar-like)<\/li><li>cough or vomiting containing blood<\/li><\/ul><\/li><li><strong>Fainting (&nbsp;syncope&nbsp;)<\/strong><ul><li>a temporary loss of consciousness due to a sudden decrease in blood supply to the brain (common)<\/li><\/ul><\/li><li><strong>Signs of problems with the blood&#8217;s ability to coagulate called the thrombotic thrombocytope purpura (TTP) such as:<\/strong><ul><li>fever and purple spots (called purpura) on the skin or in the mouth, with or without yellowing of the skin or eyes (jaundice), unexplained extreme fatigue or confusion<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong><br>Talk to your doctor if you notice any of the following:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Shortness of breath &#8211; this is very common.&nbsp;<\/strong>It could be due to your heart disease or something else, or be a&nbsp;side effect&nbsp;of Brilique.&nbsp;Shortness of breath due to Brilique is usually mild and is described as a sudden, unexpected need for air.&nbsp;This usually occurs at rest and can occur during the first weeks of treatment and can pass in many people.&nbsp;If shortness of breath gets worse or lasts longer, talk to your doctor.&nbsp;The doctor decides if it needs to be treated or examined further.<\/li><\/ul>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High level of&nbsp;uric acid&nbsp;in the blood (seen during blood tests)<\/li><li>Bleeding caused by blood disorders<\/li><\/ul>\n\n\n\n<p><strong><br>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bruises<\/li><li>Headache<\/li><li>Dizziness or a feeling that the room is spinning<\/li><li>Diarrhea or indigestion<\/li><li>Nausea<\/li><li>Constipation<\/li><li>Rash<\/li><li>Itching<\/li><li>Severe pain and swelling in the joints &#8211; signs of&nbsp;gout<\/li><li>Feeling of dizziness or dizziness, or blurred vision &#8211; signs of low&nbsp;blood pressure<\/li><li>Nasal blood<\/li><li>Heavier bleeding than normal after surgery or from injuries (eg shaving) or wounds<\/li><li>Bleeding from inside the stomach (&nbsp;stomach ulcer&nbsp;)<\/li><li>Bleeding gums<\/li><\/ul>\n\n\n\n<p><br><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reaction&nbsp;&#8211; skin rash,&nbsp;itching&nbsp;or swollen face or swollen lips \/ swollen tongue may be signs of an&nbsp;allergic reaction<\/li><li>Confusion<\/li><li>Vision problems due to blood in the eye<\/li><li>Vaginal bleeding that is heavier, or comes at a different time, than your regular menstrual bleeding<\/li><li>Bleeding in joints and muscles that cause painful swelling<\/li><li>Blood in the ear<\/li><li>Internal bleeding, which may cause dizziness or dizziness<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Brilique<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tikagrelor.&nbsp;Each film-coated tablet contains 60 mg of ticagrelor.<\/li><li>The other ingredients are&nbsp;<em>Tablet core:<\/em>&nbsp;mannitol (E421), calcium hydrogen phosphate dihydrate, sodium starch glycolate type A, hydroxypropylcellulose (E463), magnesium stearate (E470b)&nbsp;<em>Film coating:<\/em>&nbsp;hypromellose (E464), titanium dioxide (E171 (nitrous oxide)) ).<em>&nbsp;<br><br><br><\/em><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Film-coated tablets (hereinafter referred to as tablets): The tablets are round, biconvex, pink, film-coated and marked with \u201c60\u201d above \u201cT\u201d on one side.<br><\/p>\n\n\n\n<p>Brilique is marketed in:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>standard blisters (with sun \/ moon symbols) in cartons of 60 and 180 tablets<\/li><li>calendar blisters (with sun \/ moon symbols) in cartons of 14, 56 and 168 tablets<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorisation Holder:<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>AstraZeneca AB<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>AstraZeneca UK Limited<\/p>\n\n\n\n<p>Silk Road Business Park<\/p>\n\n\n\n<p>Macclesfield, Cheshire, SK10 2NA<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>AstraZeneca SA \/ NVTel: +32 2 370 48 11<\/td><td><strong>Lithuania<\/strong>UAB AstraZeneca LietuvaTel: +370 5 2660550<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Astrology Bulgaria BODYTel: +359 2 44 55 000<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>NV AstraZeneca SA \/ NVTel: + 32 2 370 48 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>AstraZeneca Czech Republic sroTel: +420 222 807 111<\/td><td><strong>Hungary<\/strong>AstraZeneca KftTel .: + 36 1 883 6500<\/td><\/tr><tr><td><strong>Denmark<\/strong>AstraZeneca A \/ STel: +45 43 66 64 62<\/td><td><strong>Malta<\/strong>Associated Drug Co.&nbsp;Ltd.Tel: + 356 2277 8000<\/td><\/tr><tr><td><strong>Germany<\/strong>AstraZeneca GmbHTel: + 49 41 03 7080<\/td><td><strong>The Netherlands<\/strong>AstraZeneca BVTel: +31 79 363 2222<\/td><\/tr><tr><td><strong>Eesti<\/strong>AstraZenecaTel: +372 6549 600<\/td><td><strong>Norway<\/strong>AstraZeneca ASTel: + 47 21 00 64 00<\/td><\/tr><tr><td><strong>Greece<\/strong>AstraZeneca AE:\u0397\u03bb: + 30 2 106871500<\/td><td><strong>Austria<\/strong>AstraZeneca \u00d6sterreich GmbHTel: +43 1 711 31 0<\/td><\/tr><tr><td><strong>Spain<\/strong>AstraZeneca Pharmac\u00e9utica Spain, SATel: + 34 91 301 91 00<\/td><td><strong>Poland<\/strong>AstraZeneca Pharma Poland Sp.&nbsp;z ooTel .: + 48 22 245 73 00<\/td><\/tr><tr><td><strong>France<\/strong>AstraZenecaTel: + 33 1 41 29 40 00<\/td><td><strong>Portugal<\/strong>AstraZeneca Pharmaceutical Products, Lda.Tel: + 351 21 434 61 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>AstraZeneca dooTel: +385 1 4628 000<\/td><td><strong>Romania<\/strong>AstraZeneca Pharma SRLTel: + 40 21 317 60 41<\/td><\/tr><tr><td><strong>Ireland<\/strong>AstraZeneca Pharmaceuticals (Ireland) DACTel: + 353 1609 7100<\/td><td><strong>Slovenia<\/strong>AstraZeneca UK LimitedTel: + 386 1 51 35 600<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hfPhone: + 354 535 7000<\/td><td><strong>Slovak Republic<\/strong>AstraZeneca AB ozTel: + 421 2 5737 7777<\/td><\/tr><tr><td><strong>Italy<\/strong>AstraZeneca SpATel: + 39 02 98011<\/td><td><strong>Finland \/ Finland<\/strong>AstraZeneca OyPuh \/ Tel: + 358 10 23 010<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>Alexander the Great:\u0397\u03bb: +357 22490305<\/td><td><\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA AstraZeneca LatvijaTel: + 371 67377100<\/td><td><strong>United Kingdom<\/strong>AstraZeneca UK LtdTel: + 44 1582 836 836<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Brilique contains an active substance called tikagrelor. It belongs to a group of medicines called antiplatelet drugs.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8445,8447,8449,2210,8440,8442,8444,8448,8446,8441,8443],"class_list":["post-6221","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-brilique","tag-brilique-side-effects","tag-brilique-tablet","tag-tablet","tag-tikagrelor","tag-tikagrelor-side-effects","tag-tikagrelor-tablet","tag-what-brilique-is-used-for","tag-what-is-brilique","tag-what-is-tikagrelor","tag-what-tikagrelor-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6221","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6221"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6221\/revisions"}],"predecessor-version":[{"id":11848,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6221\/revisions\/11848"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6221"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6221"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6221"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}