{"id":6209,"date":"2021-01-03T14:47:40","date_gmt":"2021-01-03T14:47:40","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6209"},"modified":"2021-06-28T07:38:03","modified_gmt":"2021-06-28T07:38:03","slug":"brexidol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/brexidol\/","title":{"rendered":"Brexidol &#8211; Piroxicam uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n20 mg&nbsp;piroxicam&nbsp;tablets&nbsp;<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Brexidol is and what it is used for<\/h2>\n\n\n\n<p>Brexidol has an&nbsp;anti-inflammatory&nbsp;, analgesic and antipyretic effect.&nbsp;The&nbsp;anti-inflammatory&nbsp;effect is probably due to the fact that Brexidol reduces the formation of harmful substances (&nbsp;prostaglandins&nbsp;), which are formed during&nbsp;inflammation&nbsp;.&nbsp;The analgesic effect is believed to be due to a similar mechanism.<br><\/p>\n\n\n\n<p>Brexidol is used to relieve some of the symptoms caused by&nbsp;osteoarthritis&nbsp;(&nbsp;osteoarthritis&nbsp;, a&nbsp;degenerative&nbsp;joint disease),&nbsp;rheumatoid arthritis&nbsp;(&nbsp;rheumatoid arthritis&nbsp;) and Bechterew&#8217;s disease (rheumatism of the spine), e.g.&nbsp;swelling, stiffness and joint pain.&nbsp;The drug does not cure&nbsp;arthritis&nbsp;and only helps as long as you take it.<br><\/p>\n\n\n\n<p>Before your doctor prescribes Brexidol, he or she will assess the benefit you can get from the medicine in relation to the risk of&nbsp;side effects&nbsp;.&nbsp;Your doctor may need to examine you and will tell you how often you need to be followed up because you are taking Brexidol.<br><\/p>\n\n\n\n<p>Your doctor will only prescribe Brexidol if you have not had sufficient relief from the symptoms of other non-steroidal anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Brexidol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Brexidol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to piroxicam or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have previously had ulcers, bleeding or&nbsp;perforation&nbsp;in the stomach or intestines<\/li><li>if you currently have ulcers, bleeding or&nbsp;perforation&nbsp;in the stomach or intestines.<\/li><li>if you, or anyone in your family, have or have had gastrointestinal diseases (&nbsp;inflammation&nbsp;of the stomach or intestines) that increase the susceptibility to bleeding disorders such as&nbsp;ulcerative colitis&nbsp;,&nbsp;Crohn&#8217;s disease&nbsp;,&nbsp;gastrointestinalcancer or&nbsp;diverticulitis&nbsp;(inflamed or infected pockets in the colon).<\/li><li>if you are taking other&nbsp;NSAIDs&nbsp;, including&nbsp;COX-2&nbsp;-selective&nbsp;NSAIDs&nbsp;and&nbsp;acetylsalicylic acid&nbsp;(a substance found in many painkillers and antipyretics).<\/li><li>if you are taking blood thinners, e.g.&nbsp;warfarin&nbsp;, to prevent blood clots.<\/li><li>if you have previously had a severe allergic drug reaction to Brexidol, other&nbsp;NSAIDs&nbsp;or other drugs, especially severe skin reactions (regardless of severity), e.g.&nbsp;exfoliative&nbsp;dermatitis&nbsp;, (intense skin redness with flaking of the skin in the scales or layers), vesiculobulous reactions (&nbsp;Stevens-Johnson syndrome&nbsp;, a condition with red and blistered, eroded, bloody or scaly skin) and&nbsp;toxic epidermal necrolysis&nbsp;(a disease with blistering and flaking in the upper part skin layer)<\/li><li>if you have previously had&nbsp;asthma&nbsp;, difficulty breathing, hay fever or hives with Brexidol,&nbsp;acetylsalicylic acid&nbsp;or other medicines belonging to the group of&nbsp;NSAIDs(used for pain,&nbsp;inflammation&nbsp;and fever).<\/li><li>during the last three to three months of pregnancy.<\/li><li>if you have severe&nbsp;heart failure&nbsp;or severe liver or kidney disease.<\/li><li>if you suffer from an increased risk of bleeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><em>Talk to your doctor or pharmacist before using Brexidol:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are taking other painkillers.&nbsp;For painkillers, it generally applies that higher&nbsp;doses&nbsp;than those recommended can lead to serious risks.&nbsp;Therefore, do not use different painkillers at the same time without consulting a doctor.<\/li><li>If you are over 70 years old.&nbsp;The risk of serious&nbsp;side effects&nbsp;in the stomach and intestines increases with age.&nbsp;Your doctor may therefore prescribe Brexidol together with a medicine that protects the stomach and intestines.&nbsp;If you are over 80 years old, your doctor should avoid prescribing this medicine to you.<\/li><li>If you are taking other medicines such as&nbsp;corticosteroids&nbsp;, certain antidepressants, so-called selective serotonin reuptake inhibitors (&nbsp;SSRIs&nbsp;) or&nbsp;acetylsalicylic acid&nbsp;to prevent blood clots;&nbsp;as the risk of serious&nbsp;side effects&nbsp;in the stomach and intestines increases.&nbsp;Your doctor may therefore prescribe Brexidol together with a medicine that protects the stomach and intestines.<\/li><li>If you have any of the following diseases:&nbsp;SLE&nbsp;(connective tissue disease), diseases with increased bleeding tendency, impaired heart function, cardiovascular disease including high&nbsp;blood pressure&nbsp;and&nbsp;heart failure&nbsp;, liver or kidney disease,&nbsp;diabetes too high&nbsp;cholesterol&nbsp;or blood fat value.<\/li><li>If you have chickenpox.&nbsp;This medicine should not be used.<\/li><li>If you have previously had&nbsp;edema&nbsp;(accumulation of fluid in the body) during treatment with this medicine or any other medicine that belongs to the group of&nbsp;NSAIDs&nbsp;(used for pain,&nbsp;inflammation&nbsp;and fever).<\/li><li>If you are planning a pregnancy or if you have problems getting pregnant.&nbsp;This medicine may make it harder for you to get pregnant.&nbsp;See section \u201cPregnancy, breast-feeding and fertility\u201d for more information.<\/li><li>If you have&nbsp;asthma.<\/li><li>If you smoke.<br><\/li><\/ul>\n\n\n\n<p><em>Pay attention to:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Like all&nbsp;NSAIDs&nbsp;, Brexidol can cause severe reactions in the stomach and intestines, e.g.&nbsp;pain, bleeding, sores and&nbsp;perforation&nbsp;.<br><\/li><\/ul>\n\n\n\n<p><em>Stop taking Brexidol and contact a doctor immediately if you experience any of the following symptoms:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>At the first sign of abdominal pain or signs of bleeding in the stomach or intestines, e.g.&nbsp;black or blood-stained stools or bloody vomit;&nbsp;or other new or unusual stomach symptoms.<\/li><li>If you get an&nbsp;allergic reaction&nbsp;, e.g.&nbsp;skin rash, swelling of the face, wheezing or difficulty breathing.<\/li><li>Skin reactions, which may be life-threatening (&nbsp;Stevens-Johnson syndrome&nbsp;and&nbsp;toxic epidermal necrolysis&nbsp;), have been reported with the use of Brexidol.&nbsp;It can start as red-violet target-like or round spots with blistering in the middle, often symmetrically spread, on the torso.&nbsp;Additional signs to be aware of are sores in the mouth, throat, nose, genitals or eye inflammation (red and swollen eyes).&nbsp;The skin reactions, which can be life-threatening, are often followed by&nbsp;flu-like symptoms.&nbsp;The rash can develop into blisters over large areas or skin detachment.&nbsp;The risk of serious skin reactions is greatest during the first weeks of treatment.&nbsp;If you suffer from&nbsp;Stevens-Johnson syndrome&nbsp;or&nbsp;toxic epidermal necrolysisOnce you have used piroxicam contained in Brexidol, you should never use piroxicam-containing medicines again.&nbsp;At the first symptoms or signs of these skin reactions or rashes, stop taking Brexidol immediately, and contact your doctor immediately and tell them that you are taking this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Safety and efficacy in children have not yet been established.&nbsp;No data are available.&nbsp;Treatment of children is therefore not recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Brexidol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Different drugs can sometimes affect each other.&nbsp;Your doctor may want to limit your use of Brexidol or other medicines, or you may need to take another medicine.<br><\/p>\n\n\n\n<p><em>It is especially important to mention:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are taking&nbsp;acetylsalicylic acid&nbsp;or other non-steroidal anti-inflammatory drugs<\/li><li>if you are taking&nbsp;corticosteroids, medicines used for a variety of conditions, e.g.&nbsp;allergies&nbsp;and hormonal disorders<\/li><li>if you are taking blood thinners such as&nbsp;warfarin&nbsp;or&nbsp;heparin&nbsp;to prevent blood clots<\/li><li>if you are taking methotrexate which is used to treat rheumatic diseases, severe&nbsp;psoriasis,&nbsp;and certain tumor diseases<\/li><li>if you are taking certain antidepressants, so-called selective serotonin reuptake inhibitors (&nbsp;SSRIs&nbsp;)<\/li><li>if you take lithium used in e.g.&nbsp;bipolar disease<\/li><li>if you are taking cimetidine used for heartburn and&nbsp;stomach ulcers<\/li><li>if you are taking cholestyramine which can be used to treat certain types of diarrhea or to lower elevated blood fats<\/li><li>if you are taking diuretics (eg&nbsp;furosemide&nbsp;, bumetanide or medicines belonging to the group&nbsp;thiazides&nbsp;) used in e.g.&nbsp;edema&nbsp;(accumulation of fluid in the body) and against high&nbsp;blood pressure&nbsp;.<\/li><li>if you are taking medicines used for e.g.&nbsp;high&nbsp;blood pressure,&nbsp;heart failure, angina (&nbsp;ACE inhibitor,&nbsp;angiotensin&nbsp;II&nbsp;antagonist&nbsp;s or beta-receptor blocking drugs)<\/li><li>if you are taking medicines that suppress the immune system e.g.&nbsp;ciclosporin or tacrolimus<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Pregnant women should not use Brexidol during the last three months of pregnancy.&nbsp;Taking Brexidol should be avoided by women who are planning to become pregnant or are pregnant.&nbsp;Treatment during any part of the pregnancy should only be done after a doctor&#8217;s&nbsp;prescription.<br><\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Brexidol passes into breast milk.&nbsp;As the safety of newborns has not been studied, it is not recommended that breastfeeding mothers use Brexidol.<br><\/p>\n\n\n\n<p><em>Fertility<\/em><\/p>\n\n\n\n<p>Brexidol can affect the chances of getting pregnant and is not recommended in women trying to conceive.&nbsp;Talk to your doctor before using this medicine if you are trying to conceive or undergo a fertility test.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Brexidol has no or negligible effect on the ability to drive and use machines.&nbsp;However, this medicine may cause&nbsp;side effects&nbsp;such as dizziness, tiredness and blurred vision, see section 4 \u201cPossible side effects\u201d for further information.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Brexidol contains lactose and sodium<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie&nbsp;essentially &#8216;sodium-free&#8217;.&nbsp;is next to &#8220;sodium-free&#8221;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Brexidol<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Your doctor will examine you regularly to make sure you are taking the correct&nbsp;dose of Brexidol.&nbsp;Your doctor will adjust your&nbsp;dosage&nbsp;so that you get the lowest&nbsp;dose&nbsp;that provides the best relief from your symptoms.&nbsp;Never&nbsp;change your&nbsp;dose&nbsp;without first consulting your doctor.<br><\/p>\n\n\n\n<p><em>Adults and the elderly:<\/em><\/p>\n\n\n\n<p>The maximum&nbsp;dose&nbsp;is 20 mg Brexidol once a day.<\/p>\n\n\n\n<p>If you are older, your doctor may prescribe a lower&nbsp;dose.&nbsp;If you are over 80 years old, your doctor should avoid prescribing this medicine to you.<br><\/p>\n\n\n\n<p>The tablets should be swallowed with water.<\/p>\n\n\n\n<p>The tablet can be divided into two equal&nbsp;doses.<\/p>\n\n\n\n<p>Divide the tablet by placing it on a flat surface with the notch facing up.&nbsp;Gently press with your thumb to divide the tablet into two equal parts.<br><\/p>\n\n\n\n<p>Your doctor may prescribe Brexidol together with any other medicine that may protect your stomach and intestines from any&nbsp;side effects.<br><\/p>\n\n\n\n<p><strong>Do not&nbsp;increase the dose&nbsp;one<\/strong><\/p>\n\n\n\n<p>If you have the impression that the medicine does not have the desired effect, contact your doctor.<\/p>\n\n\n\n<p>Symptoms of overdose may include nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, drowsiness, unconsciousness, seizures and impaired respiratory function (&nbsp;respiratory depression&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Brexidol<\/h2>\n\n\n\n<p>Take the medicine as soon as you remember.&nbsp;If it is soon time to take the next tablet, do not take the&nbsp;dose&nbsp;you forgot, just take the next tablet at the right time.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>The most frequently reported&nbsp;adverse event&nbsp;increases have been&nbsp;side-effects&nbsp;is from the gastrointestinal tract.<br><\/p>\n\n\n\n<p>Stop taking Brexidol and contact a doctor immediately or see your nearest emergency department if you experience any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An extremely severe&nbsp;allergic reaction&nbsp;with skin rash usually in the form of blisters or sores in the oral cavity and eyes as well as other mucous membranes such as genitals.&nbsp;The very rare&nbsp;side effect&nbsp;may affect up to 1 in 10,000 people.&nbsp;See section 2 \u201cWarnings and Cautions\u201d for more information.&nbsp;<\/li><li>Toxic&nbsp;epidermal&nbsp;necrolysis: Severe widespread skin damage (skin detachment of the epidermis and superficial mucous membranes).&nbsp;Very rare&nbsp;side effect&nbsp;, may affect up to 1 in 10,000 people.&nbsp;See section 2 \u201cWarnings and Precautions\u201d for more information.<\/li><li>Severe&nbsp;allergic reaction&nbsp;(&nbsp;anaphylaxis&nbsp;) with symptoms such as skin rash, difficulty swallowing, wheezing or difficulty breathing, fainting and drop in blood pressure.&nbsp;The rare&nbsp;side effect&nbsp;may affect up to 1 in 1,000 people.<\/li><li>Stomach pain or signs of bleeding in the stomach and intestines, e.g.&nbsp;black or blood-stained stools or bloody vomit;&nbsp;or other new or unusual stomach symptoms.&nbsp;An uncommon&nbsp;side effect&nbsp;may affect up to 1 in 100 people.&nbsp;See section 2 \u201cWarnings and Cautions\u201d for more information.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;that may occur:<\/strong><br><\/p>\n\n\n\n<p><em>Common (&nbsp;<\/em><em>may affect&nbsp;<\/em><em>up to 1&nbsp;<\/em><em>in&nbsp;<\/em><em>10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anemia<\/li><li>headache<\/li><li>feeling dizzy or moving (&nbsp;vertigo&nbsp;),&nbsp;tinnitus&nbsp;(ringing in the ears or ringing in the ears)<\/li><li>diarrhea, acid regurgitation&nbsp;<\/li><li>rash,&nbsp;itching<\/li><li>altered blood levels (increase in&nbsp;urea&nbsp;in the blood)<br><\/li><\/ul>\n\n\n\n<p><em>Uncommon (&nbsp;<\/em><em>may affect&nbsp;<\/em><em>up to 1&nbsp;<\/em><em>in 100&nbsp;<\/em><em>people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness, fatigue<\/li><li>dimsyn<\/li><li>gastric ulcer&nbsp;<\/li><li>fluid retention (&nbsp;edema&nbsp;), elevated liver values<br><\/li><\/ul>\n\n\n\n<p><em>Rare (&nbsp;<\/em><em>may affect&nbsp;<\/em><em>up to 1&nbsp;<\/em><em>in&nbsp;<\/em><em>1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>change in the number of&nbsp;blood cells&nbsp;(&nbsp;aplastic anemia,&nbsp;hemolytic anemia,&nbsp;thrombocytopenia,&nbsp;leukopenia,&nbsp;eosinophilia&nbsp;)<\/li><li>hearing loss<\/li><li>asthma, respiratory cramps\/difficulty breathing with symptoms such as wheezing and wheezing, runny nose (&nbsp;rhinitis&nbsp;)<\/li><li>jaundice, hepatitis<\/li><li>photosensitivity;&nbsp;hives;&nbsp;a disease with symptoms such as purple rashes that look like bruises,&nbsp;inflammation&nbsp;of the joints, abdominal pain, and bleeding from the intestine (Henoch-Sch\u00f6nlein purpura);&nbsp;a skin and mucous membrane disease with rash and\/or blisters (erythema multiforme)<\/li><li>perforation&nbsp;(holes) in the stomach or intestines<\/li><li>kidney effects,&nbsp;kidney failure<\/li><li>increased tendency to bleed<br><\/li><\/ul>\n\n\n\n<p>In rare cases, severe skin infections are associated with chickenpox.<br><\/p>\n\n\n\n<p><em>Has been reported (&nbsp;<\/em><em>occurs in an unknown number of users&nbsp;<\/em><em>)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>depression, abnormal dreams, hallucinations, difficulty sleeping, states of confusion, mood swings, nervousness<\/li><li>vascular inflammation<\/li><li>stomach upset, constipation, discomfort or pain in the upper abdomen, bloating, nausea, vomiting, inflammation in\/near the mouth, gastritis, black and foul-smelling stools, vomiting with blood in,&nbsp;inflammation&nbsp;of the pancreas<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Brexidol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is 191.2 mg piroxicam-\u00df-cyclodextrin equivalent to piroxicam 20 mg.<\/li><li>The other ingredients are&nbsp;lactose monohydrate&nbsp;(102.8 mg), magnesium stearate,&nbsp;colloidal&nbsp;silica, sodium starch glycolate, corn starch pregelatinized, crospovidone. See &#8220;Brexidol contains&nbsp;lactose&nbsp;and sodium&#8221; in section 2 of this leaflet for further information.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Brexidol is a pale yellow hexagonal tablet with a score line on one side.&nbsp;The tablet can be divided into two equal&nbsp;doses.<br><\/p>\n\n\n\n<p>Brexidol is available in pack sizes of 7 and 20 tablets in thermoformed PVC \/ PVdC blisters with Al \/ PVdC closure.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Chiesi Farmaceutici SpA<\/p>\n\n\n\n<p>via Palermo 26 \/ A<\/p>\n\n\n\n<p>43122 Parma<\/p>\n\n\n\n<p>Italy<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Chiesi Farmaceutici SpA<\/p>\n\n\n\n<p>via San Leonardo 96<\/p>\n\n\n\n<p>43122 Parma<\/p>\n\n\n\n<p>Italy<br><\/p>\n\n\n\n<p>Chiesi SAS<\/p>\n\n\n\n<p>2 rue des Doctors Alberto and Paolo Chiesi<\/p>\n\n\n\n<p>41260 La Chauss\u00e9e Saint Victor<\/p>\n\n\n\n<p>France<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Brexidol has an anti-inflammatory , analgesic and antipyretic effect. The anti-inflammatory effect is probably due to the fact that Brexidol reduces the formation of harmful substances ( prostaglandins ), which are formed during inflammation . The analgesic effect is believed to be due to a similar mechanism.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8497,8499,8501,8491,8493,8496,8495,8500,8498,8492,8494],"class_list":["post-6209","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-brexidol","tag-brexidol-side-effects","tag-brexidol-tablet","tag-piroxicam","tag-piroxicam-side-effects","tag-piroxicam-tablet","tag-side-effects-of-piroxicam","tag-what-brexidol-is-used-for","tag-what-is-brexidol","tag-what-is-piroxicam","tag-what-piroxicam-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6209","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6209"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6209\/revisions"}],"predecessor-version":[{"id":11874,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6209\/revisions\/11874"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}