\n\n10 mg \/ mL infusion solution
esmolol hydrochloride<\/p>\n\n\n\n
Brevibloc contains a substance called esmolol, which belongs to a group of medicines called “beta-blockers”. Brevibloc works by controlling the speed and force of your heartbeat and can help lower your blood pressure.
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Brevibloc is used to treat:<\/p>\n\n\n\n
\u2022 Problems with heart rate one, when your heart beats too fast<\/p>\n\n\n\n
\u2022 Pulse problems and increased blood pressure if this occurs during or immediately after surgery
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Esmolol contained in Brevibloc may also be approved for the treatment of other conditions not mentioned in this leaflet. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.
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You will not receive Brevibloc if any of the above apply to you. Consult your doctor, nurse, or pharmacist before receiving Brevibloc if you are not sure if you have any of these conditions.
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Talk to your doctor, nurse, or pharmacist before receiving Brevibloc. Your doctor will be careful to ensure the following when you receive this medicine if:<\/p>\n\n\n\n
Change of dose one is usually not necessary if you have liver problems
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If any of the above apply to you (or you are not sure), ask your doctor, nurse, or pharmacist for advice before taking this medicine. You may need careful checks and the treatment may change.
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Tell your doctor, nurse, or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription, including herbal remedies and herbal remedies. Your doctor will check that any other medicines you are taking do not change the way Breviblock works.
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In particular, tell your doctor or pharmacist if you are taking any of the following:<\/p>\n\n\n\n
If you are not sure if any of the above applies to you, talk to your doctor, nurse, or pharmacist before using Brevibloc.
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Tests that can be done while you are being treated with Brevibloc<\/strong><\/p>\n\n\n\n Using medicines like Brevibloc for a long period of time can reduce the power of your heartbeat.<\/p>\n\n\n\n Because Brevibloc is only used for a limited time, this is unlikely to happen to you. During treatment, you will be closely monitored and treated with Brevibloc will be reduced or discontinued completely if the force of your heartbeat decreases.<\/p>\n\n\n\n Your doctor will also check your blood pressure while you are being treated with Brevibloc.<\/p>\n\n\n\n Ask your doctor or pharmacist for advice before taking any medicine. You should not be given Brevibloc if you are pregnant or think you may be pregnant. Tell your doctor if you are breast-feeding. Brevibloc can pass into breast milk so you should not be given Brevibloc if you are breast-feeding.<\/p>\n\n\n\n Brevibloc contains approximately 700 mg of sodium per bag. This can be important if you<\/p>\n\n\n\n controls the amount of sodium in your diet. Recommended dose<\/strong><\/p>\n\n\n\n Your doctor will determine how much medicine you need and how long your treatment should last. Brevibloc is not normally given for more than 24 hours. How to get Brevibloc<\/strong><\/p>\n\n\n\n Brevibloc is ready to use and you will get it through a slow injection ( infusion ) via a needle that is inserted into a vein in your arm.<\/p>\n\n\n\n Brevibloc must not be mixed with sodium bicarbonate or other medicinal products. The treatment is given in two steps:<\/em> Step one: a large dose is given for one minute. This quickly increases the levels in your blood.<\/p>\n\n\n\n – Step two: then give a smaller dose for four minutes.<\/p>\n\n\n\n – Steps one and two can then be repeated and adjusted according to how your heart responds. As soon as an improvement has occurred, step one (the large dose one) is stopped, and step two (the small dose one) is reduced if necessary.<\/p>\n\n\n\n – Once you have reached a stable state, you may be given another medicine for your heart, while your dose of Brevibloc is gradually reduced.<\/p>\n\n\n\n – If your heart rate or blood pressure increases during an operation or shortly after you recover from it, you can receive a larger dose of Brevibloc for a short time. Older<\/strong><\/p>\n\n\n\n Your doctor will start treatment with a lower dose. Children<\/strong><\/p>\n\n\n\n Children up to the age of 18 should not be given Brevibloc.<\/p>\n\n\n\n <\/p>\n\n\n\n If you take more Brevibloc than you should<\/strong> Because you are receiving Brevibloc from a trained and qualified person, it is unlikely that you will receive too much. However, should this occur, your doctor will stop giving you Brevibloc and you will receive other treatment if needed. If you think a dose of Brevibloc has been missed<\/strong> Because you are receiving Brevibloc from a trained and qualified person, it is unlikely that you will miss a dose. However, if you think you have missed a dose, contact your doctor, nurse, or pharmacist as soon as possible. If you stop taking Brevibloc<\/strong> Sudden discontinuation of Brevibloc treatment may cause symptoms such as rapid heartbeat ( tachycardia ) and high blood pressure ( hypertension ) to return. To avoid this, your doctor should discontinue treatment gradually. If it is known that you have coronary heart disease (which may be associated with a history of angina or heart attack), your doctor will need to take special care when stopping treatment with Brevibloc. If you have any further questions on the use of this product, ask your doctor, nurse, or pharmacist.<\/strong><\/p>\n\n\n\n <\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Most side effects generally go away within 30 minutes of stopping treatment with Brevibloc. The following side effects have been reported with Brevibloc: Contact your doctor, nurse, or pharmacist if you notice any of the following side effects that may be serious. Infusion one may also need to be stopped.<\/strong> Very common<\/strong> (may affect more than 1 user in 10)<\/p>\n\n\n\n \u2022 Drop in blood pressure. This can be quickly corrected by reducing the dose of Brevibloc or stopping treatment completely. Your blood pressure will be measured frequently during treatment<\/p>\n\n\n\n \u2022 Abnormal sweating Common<\/strong> (may affect less than 1 user in 10)<\/p>\n\n\n\n Uncommon<\/strong> (may affect less than 1 user in 100)<\/p>\n\n\n\n Very rare<\/strong> (may affect less than 1 in 10,000 users)<\/p>\n\n\n\n No known frequency<\/strong> (number of persons involved is unknown)<\/p>\n\n\n\n If you get any side effects, talk to your doctor, nurse, or pharmacist. This also applies to side effects that are not mentioned in this information. You can also report side effects directly to (see details below). By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n The Medical Products Agency<\/p>\n\n\n\n Box 26<\/p>\n\n\n\n 751 03 Uppsala<\/p>\n\n\n\n Website: www.lakemedelsverket.se Reporting of side effects<\/em><\/p>\n\n\n\n If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information<\/p>\n\n\n\n \u2022 Keep out of sight and reach of children<\/p>\n\n\n\n \u2022 Do not use this medicine after the expiry date which is stated on the label after EXP. The expiration date is the last day of the specified month<\/p>\n\n\n\n \u2022 Do not remove the outer bag until the product is to be used<\/p>\n\n\n\n \u2022 Do not store above 25 \u00b0 C.<\/p>\n\n\n\n \u2022 Store in a cool place. Do not freeze.<\/p>\n\n\n\n \u2022 Opened product is stable for 24 hours at 2 \u00b0 C – 8 \u00b0 C but should be used immediately after opening.<\/p>\n\n\n\n \u2022 Do not use Brevibloc if you notice particles in the solution or if it is discolored. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Brevibloc is a clear, colorless to light yellow, sterile solution for intravenous infusion(slow injection ). Available in 250 ml of plastic bags (latex-free).<\/p>\n\n\n\n Baxter Medical AB<\/p>\n\n\n\n PO Box 63<\/p>\n\n\n\n 164 94 Kista<\/p>\n\n\n\n Baxter SA<\/p>\n\n\n\n Boulevard Ren\u00e9 Branquart, 80<\/p>\n\n\n\n 7860 Lessines<\/p>\n\n\n\nPregnancy and breastfeeding<\/h2>\n\n\n\n
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<\/p>\n\n\n\nBrevibloc contains sodium<\/h2>\n\n\n\n
<\/p>\n\n\n\n3. How to get Brevibloc<\/h2>\n\n\n\n
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<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/p>\n\n\n\n5. How to store Brevibloc<\/h2>\n\n\n\n
<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing authorization holders are:<\/h3>\n\n\n\n
Manufacturer:<\/h3>\n\n\n\n