{"id":6158,"date":"2021-01-02T15:15:10","date_gmt":"2021-01-02T15:15:10","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6158"},"modified":"2023-01-22T07:31:07","modified_gmt":"2023-01-22T07:31:07","slug":"bondil","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bondil\/","title":{"rendered":"Bondil &#8211; Alprostadil Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Bondil 500 mg, Bondil 1000 mg\u00a0Urethral\u00a0Pin Alprostadil<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Bondil Is And Bondil Used For<\/h2>\n\n\n\n<p>Bondil contains the active substance&nbsp;alprostadil. <strong>Bondil is used in the treatment and diagnosis of erection problems. Bondil increases blood flow in the penis which leads to&nbsp;an erection.<\/strong><br>Alprostadil contained&nbsp;in Bondil may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Bondil<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Bondil<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to\u00a0alprostadil\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If for some reason your penis has an abnormal shape such as a sharp bend (such as Peyronie&#8217;s disease).<\/li><li>If you have\u00a0a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/urinary-tract-infection\/\">urinary tract infection<\/a>\u00a0or\u00a0infection\u00a0of the penis.<\/li><li>If you have a disease that can increase the risk of prolonged\u00a0erection, for example, a blood disease, bone marrow tumor (multiple\u00a0myeloma\u00a0), or if you have an increased risk of blood clots.<\/li><li>If you have previously experienced recurrent prolonged and painful\u00a0erections.<\/li><li>If you have been advised not to have sex for health reasons such as heart problems or if you have recently had a\u00a0stroke.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Bondil:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you know you have a bleeding disorder because an incorrect introduction of Bondil can cause superficial damage to the urethra, which may result in minor bleeding.\u00a0If you have a disease that is transmitted through the blood, this can increase the risk of transmitting that disease to your partner.<\/li><li>If you have previously had a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/being-related-to-someone-who-has-a-psychotic-illness\/\">mental illness<\/a> or a state of dependence.<\/li><li>If you have had a mini-stroke\u00a0(\u00a0TIA\u00a0attack) or have an unstable cardiovascular disease.<\/li><li>If you have coronary heart disease,\u00a0heart failure,\u00a0or lung disease.\u00a0If you have had these problems, sexual stimulation can lead to heart and lung problems.<\/li><li>If you have a penis implant.<\/li><\/ul>\n\n\n\n<p>If your&nbsp;erection&nbsp;lasts 4 hours or longer, contact a doctor or healthcare professional immediately. If your female partner is pregnant, a condom should be used during intercourse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Bondil<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This is especially true when using the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Antihypertensives (medicines used to treat high&nbsp;blood pressure&nbsp;).&nbsp;Bondil may affect how well that medicine works.<\/li><li>Anticoagulants&nbsp;and inhibitors of&nbsp;platelet aggregation&nbsp;(drugs that thin your blood).&nbsp;The risk of urethral bleeding increases.<\/li><li>Sympathomimetics&nbsp;(drugs that act on the sympathetic nervous system).&nbsp;Bondil may have a worse effect.<\/li><li>Vasoactive drugs (which change the diameter of your blood vessels).&nbsp;Your&nbsp;blood pressure&nbsp;may rise or fall.<\/li><li>Viagra and other drugs for erection problems.&nbsp;These may affect the effect of Bondil.<\/li><li>Muscle relaxants or other medications that cause&nbsp;erections&nbsp;give the risk of prolonged&nbsp;erections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If your partner is pregnant, if you think your partner may be pregnant, or if you are planning to have a baby, a condom should be used during intercourse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>During treatment with Bondil, dizziness and fainting may occur.&nbsp;In patients who experience these symptoms, they usually occur at the time of insertion or within one hour after the introduction of Bondil into the urethra.&nbsp;This should be taken into account when sharper attention is required, eg when driving a car.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Bondil<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always use this medicine exactly as your doctor has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li>Dose\u00a0one is determined by the doctor who adjusts it individually for you.<\/li><li>The usual starting dose is 500 micrograms.\u00a0If this does not provide a sufficient\u00a0erection<strong>, do not increase the\u00a0dose\u00a0on your own.\u00a0<\/strong>Contact\u00a0your\u00a0doctor who will try a higher\u00a0dose\u00a0for you.<\/li><li>You should not use more than two\u00a0doses\u00a0within a period of 24 hours.\u00a0The maximum single dose is 1000 micrograms.<\/li><li><strong>Instructions for use<\/strong><ul><li>Bondil should be at room temperature during use.<\/li><li>Urinate before using Bondil.\u00a0It is easier to insert the applicator if the urethra is damp.\u00a0The drug dissolves in the fluid that remains in the urethra.<\/li><\/ul><\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Meda\/Media\/Bondil\/Bondil.jpg\" alt=\"Picture 1\"\/><\/a><\/figure>\n\n\n\n<p>1. Open the foil pouch and slide the applicator out of the pouch.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>2. Unscrew the protective sleeve on the applicator.&nbsp;<strong>Do not push in or pull out the button on the top of the applicator!<\/strong>Try not to touch the tube or its end.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>3. The drug is located at the end of the tube.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>4. Sit or stand and stretch the penis upwards, gently squeezing the glans.&nbsp;This is to straighten and open the urethra.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>5. Then carefully insert the applicator tube into the urethra.&nbsp;It is important that the pipe is inserted all the way up to the collar of the applicator in order for you to have a good effect.&nbsp;If it feels uncomfortable, pull out the tube slightly and then insert it again.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>6. When the tube is inserted, press the button on the applicator&nbsp;<em>as far as it will go<\/em>&nbsp;.&nbsp;Hold the applicator in this position for 5 seconds.&nbsp;This is important to ensure that the applicator is emptied of all medicines.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>7. Gently rock the applicator so that the applicator can be emptied of the medicine.&nbsp;Then pull out the applicator while still holding the penis upright.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><\/thead><tbody><tr><td>8. Keep the penis upright and outstretched and massage for&nbsp;<em>at least 10 seconds<\/em>&nbsp;so that the medicine spreads along the walls of the urethra.&nbsp;If you feel it sting, massage for another 30-60 seconds or until the burning subsides.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19980417000047#\" rel=\"noopener\"><\/a><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Erection\u00a0one starts within 5-10 minutes.\u00a0Active foreplay has\u00a0a positive\u00a0effect on\u00a0erection.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Bondil Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;The side effects&nbsp;are usually mild and disappear soon.<\/p>\n\n\n\n<p><strong>If you get any of the following symptoms, contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have a long-lasting\u00a0erection\u00a0that lasts longer than four hours\u00a0(less common side effect)<\/li><li>Your penis gets scarred or bent\u00a0(rare side effect)<\/li><li>Your testicles or scrotum become red, swollen, sore, or if tissue nodules appear.\u00a0These are called spermatocele and are cysts that contain sperm\u00a0(less common side effect)<\/li><\/ul>\n\n\n\n<p><em>Very common (affects more than 1 user in 10)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Burning sensation in the urethra.<\/li><li>Painful penis.<\/li><\/ul>\n\n\n\n<p><em>Common (affects more than 1 user in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Dizziness<\/li><li>Muscle spasms<\/li><li>Low&nbsp;blood pressure<\/li><li>Minor bleeding from the urethra<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">Pain<\/a> in the testicles<\/li><li>Bruises on the penis<\/li><li>Increased&nbsp;erection<\/li><\/ul>\n\n\n\n<p><em>Uncommon (affects less than 1 user in 100, more than 1 user in 1000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fainting or fainting<\/li><li>Deteriorated or improved sensation<\/li><li>Swelling of blood vessels in the legs<\/li><li>Pain in the legs<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Cold<\/a><\/li><li>Pain in the pelvic floor (between the penis and the rectum)<\/li><li>Increased&nbsp;heart rate<\/li><li>Dilation of your blood vessels which makes you feel dizzy<\/li><li>Blood vessel disorders such as bleeding from certain blood vessels<\/li><li>Nausea<\/li><li>Skin rash that may cause&nbsp;itching&nbsp;or&nbsp;redness<\/li><li>Increased sweating<\/li><li>More urgent need to urinate and need to urinate more often than usual<\/li><li>Pain or difficulty urinating<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/blood-in-the-urine\/\">Blood in the urine<\/a><\/li><li>Increased levels of&nbsp;creatinine&nbsp;in the blood<\/li><li>Priapism (prolonged&nbsp;erection&nbsp;)<\/li><li>Redness, swelling, or pain in the testicles or scrotum may develop.&nbsp;Harmless tissue nodules that contain sperm on the penis (spermatocele) can occur.&nbsp;The penis may feel numb.<\/li><li>Uncomfortable or painful&nbsp;erections&nbsp;or no&nbsp;erections&nbsp;at all.<\/li><li>Altered ejaculation.<\/li><li>Swollen or tight foreskin and\/or swelling at the end of the penis.<\/li><\/ul>\n\n\n\n<p><em>Rare (affects less than 1 user in 1,000, more than 1 in 10,000 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Urinary tract infection<\/li><li>Problems from the penis can result in it being scarred or bent, especially after long-term use of Bondil.<\/li><\/ul>\n\n\n\n<p><em>Very rare (affects less than 1 user in 10,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hives.<\/li><\/ul>\n\n\n\n<p>Your female partner may experience&nbsp;itching&nbsp;or burning in the vagina, which may be due to the resumption of intercourse.<\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor or pharmacist.&nbsp;This also applies to&nbsp;side effects&nbsp;that are not mentioned in this information.&nbsp;You can also report&nbsp;side effects directly (see details below).&nbsp;By reporting&nbsp;side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Bondil<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/li><li>The packaging currently in use is stable for 14 days when stored at a maximum of 30 \u00b0 C.&nbsp;Do not leave Bondil in a car or other places where it may be exposed to temperatures higher than 30 \u00b0 C.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and label after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Bondil urethral&nbsp;pins&nbsp;are discarded as normal household waste.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;alprostadil&nbsp;500 micrograms or 1000 micrograms.<\/li><li>The other ingredient is macrogol.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Sterile pin in disposable applicator in the bag.<\/li><li>1 x 1\u00a0applicator, 1 x 2\u00a0applicator, 1 x 6\u00a0applicator, 1 x 10\u00a0applicator.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Meda AB<\/p>\n\n\n\n<p>Box 906<\/p>\n\n\n\n<p>170 09 Solna<\/p>\n\n\n\n<p>Tel: 08 &#8211; 630 19 00<\/p>\n\n\n\n<p>Email: info@meda.se<br>L\u00e4kemedelsverket, Box 26, 751 03 Uppsala.&nbsp;Website:&nbsp;www.lakemedelsverket.se<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bondil injection is used to treat erectile dysfunction in men (also called sexual impotence).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[7654,7656,8617,8619,8616,8621,8615,8620,7655,8618],"class_list":["post-6158","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-alprostadil","tag-alprostadil-side-effects","tag-bondil","tag-bondil-side-effects","tag-side-effects-of-alprostadil","tag-side-effects-of-bondil","tag-what-alprostadil-is-used-for","tag-what-bondil-is-used-for","tag-what-is-alprostadil","tag-what-is-bondil"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6158"}],"version-history":[{"count":35,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6158\/revisions"}],"predecessor-version":[{"id":45894,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6158\/revisions\/45894"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}