Contact your doctor if you are taking any of these medicines. <\/strong>You should not stop treatment without talking to your doctor.
<\/p>\n\n\n\nTalk to your doctor or pharmacist if you are taking:<\/strong><\/p>\n\n\n\n- antacids<\/strong> to treat stomach ulcers, heartburn, or reflux disease, containing aluminum and\/or magnesium hydroxide<\/li>
- mineral supplements<\/strong> or vitamins,<\/strong> which contain magnesium or iron<\/li><\/ul>\n\n\n\n
\u2192 If<\/strong> you are taking any of these medicines, talk to your doctor or pharmacist before taking Biktarvy<\/strong> .<\/p>\n\n\n\nAntacids and magnesium supplements: you must take Biktarvy at least 2 hours before antacids or supplements that contain aluminum and\/or magnesium. Or you can take Biktarvy together with food for at least 2 hours afterward<\/strong>.<\/p>\n\n\n\nIron supplements:<\/strong> you must take Biktarvy at least 2 hours before<\/strong> iron supplements, or you can take them with food.<\/p>\n\n\n\nPregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li>
- Tell your doctor immediately if you become pregnant and ask about the possible benefits or risks of your antiretroviral treatment for you and your baby.<\/li><\/ul>\n\n\n\n
If you have taken Biktarvy during pregnancy, your doctor may request regular blood tests and other diagnostic tests to check your baby’s development. For children whose mother has taken reverse nucleotide-type transcriptase inhibitors (NRTIs) during pregnancy, the benefit of HIV protection outweighs the risk of side effects.
<\/p>\n\n\n\n
Do not breast-feed during treatment with Biktarvy. <\/strong>This is because some of the active substances in this medicine pass into breast milk. To avoid transmitting HIV to your baby through breast milk, do not breast-feed your baby. If you really want to breastfeed, talk to your doctor first.<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
Confession can cause dizziness. Do not drive or use any tools or machines if you feel dizzy while taking Biktarvy.
<\/p>\n\n\n\n
Confession view contains excipients<\/h2>\n\n\n\n
Confession view contains sodium<\/strong><\/p>\n\n\n\nThis medicine contains less than 1 mmol (23 mg) sodium per tablet, ie it is essentially ‘sodium-free’.<\/p>\n\n\n\n
<\/p>\n\n\n\n
3. How to use Biktarview<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n
The recommended dose is:<\/strong>
<\/p>\n\n\n\nAdults:<\/strong> one tablet a day with or without food.
<\/p>\n\n\n\nYou must not chew, crush, or split the tablet.
<\/p>\n\n\n\n
\u2192 Talk to your doctor or pharmacist if you are taking:<\/strong><\/p>\n\n\n\n- antacids<\/strong> to treat stomach ulcers, heartburn, or reflux disease, containing aluminum and\/or magnesium hydroxide<\/li>
- mineral supplements<\/strong> or vitamins,<\/strong> which contain magnesium or iron<\/li><\/ul>\n\n\n\n
\u2192 See section 2 for more information<\/strong> on taking these medicines with Biktarvy.
<\/p>\n\n\n\nIf you are on dialysis, take your daily dose of Biktarvy after dialysis has been completed.<\/p>\n\n\n\n
If you take more Biktarvy than you should<\/h2>\n\n\n\n
If you take more than the prescribed dose of Biktarvy you may be at greater risk of side effect s of this medicine (see section 4, Possible side effects s<\/em> ).<\/p>\n\n\n\nContact your doctor or nearest emergency department immediately for advice. Save the jar so you can easily describe what you have taken.<\/p>\n\n\n\n
If you forgot to take the Confessional view<\/h2>\n\n\n\n
It is important that you do not miss any dose of Biktarvy.
<\/p>\n\n\n\n
If you miss a dose:<\/p>\n\n\n\n
- If you remember it within 18 hours<\/strong> of the time you usually take Biktarvy, you must take the tablet as soon as possible. Then take the next dose as usual.<\/li>
- If you notice it after 18 hours or more, do not take the missed dose<\/strong>. Wait and take the next dose at the usual time.<\/li><\/ul>\n\n\n\n
If you vomit<\/strong> in less than 1 hour after a dose of Biktarvy, take a new tablet. If you vomit more than 1 hour after taking Biktarvy, you do not need to take a new tablet until the next normally scheduled dose.<\/p>\n\n\n\nDo not stop taking Confession View<\/h2>\n\n\n\n
Do not stop taking Biktarvy without talking to your doctor. <\/strong>If you stop taking Biktarvy, this can seriously affect how well the future treatment works. If for any reason you stop taking Biktarvy, talk to your doctor before taking Biktarvy tablets again.
<\/p>\n\n\n\nWhen your Biktarvy supply starts to run low,<\/strong> get more from your<\/strong> doctor or pharmacist. This is very important because the amount of virus can start to increase even if you only stop taking the medicine for a short time. The disease can then become more difficult to treat.
<\/p>\n\n\n\nIf you have both HIV – infection and hepatitis B,<\/strong> it is especially important not to stop Biktarvy treatment without first talking to your doctor. You may need to submit blood samples for several months after stopping treatment. In some patients with advanced liver disease or cirrhosis, it is recommended not to discontinue treatment, as it may lead to worsening of the liver disease, and it may be life-threatening.
<\/p>\n\n\n\n\u2192 Tell your doctor immediately<\/strong> about any new and unexpected symptoms that occur after stopping treatment, especially symptoms that you usually associate with your hepatitis B infection.
<\/p>\n\n\n\nIf you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
Possible side effects: Contact a doctor immediately<\/strong><\/p>\n\n\n\n- Signs of inflammation or infection. <\/strong>In some patients with advanced HIV – infection ( AIDS ) who have a history of opportunistic infection, you ( infection s that occur in people with weakened immune systems) may be signs and symptoms of inflammation from previous infections that occur shortly after HIV treatment is started. It is believed that these symptoms are due to the fact that the body’s immune system has been strengthened so that the body can fight infections that may have been present without giving any clear symptoms.<\/li>
- Autoimmune diseases<\/strong> , where the immune system attacks healthy body tissue, can also occur after you start taking medicines for HIV – infection. Autoimmune diseases can occur many months after starting treatment. Be observant of symptoms of infection or other symptoms such as:
- muscle weakness<\/li>
- weakness that begins in the hands and feet and moves towards the torso<\/li>
- palpitations, tremors, or hyperactivity<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 If you notice these or other symptoms of inflammation or infection, tell your doctor immediately.<\/strong>
<\/p>\n\n\n\nCommon side effects are<\/strong><\/p>\n\n\n\n(may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n- Depression<\/li>
- abnormal dreams<\/li>
- headache<\/li>
- dizziness<\/li>
- diarrhea<\/li>
- nausea<\/li>
- fatigue<\/li><\/ul>\n\n\n\n
Uncommon side effects are<\/strong><\/p>\n\n\n\n( may affect up to 1 in 100 people<\/em> )<\/p>\n\n\n\n- low red blood cell count ( anemia<\/em> )<\/li>
- vomiting<\/li>
- abdominal pain<\/li>
- indigestion which results in discomfort after meals ( dyspepsia<\/em> )<\/li>
- gas production ( flatulence<\/em> )<\/li>
- swelling of the face, lips, tongue, or throat ( angioedema<\/em> )<\/li>
- itching ( pruritus<\/em> )<\/li>
- rash<\/li>
- hives ( urticaria )<\/em><\/li>
- joint pain ( arthralgia<\/em> )<\/li>
- suicidal ideation and suicide attempts (especially in patients with a history of depression or mental health problems)<\/li>
- anxiety<\/li>
- sleep disorders<\/li><\/ul>\n\n\n\n
Blood tests may also show:<\/em><\/p>\n\n\n\n- higher levels of substances called bilirubin and\/or serum creatinine in the blood<\/li><\/ul>\n\n\n\n
\u2192 If any side effects get worse, talk to your doctor.<\/strong>
<\/p>\n\n\n\nOther effects that can be seen with HIV treatment<\/strong>
<\/p>\n\n\n\nThe frequency of the following side effects is unknown (frequency cannot be calculated from the available data).<\/p>\n\n\n\n
- Skeletal problem. <\/strong>Some patients taking combination antiretroviral medicines such as Biktarvy may develop a skeletal disease called osteonecrosis<\/em> (bone tissue dies due to lost blood supply to the skeleton). Some of the many risk factors for developing this disease are long-term use of this type of drug, treatment with corticosteroids, alcohol consumption, a very weak immune system, and obesity. Signs of osteonecrosis are:
- joint stiffness<\/li>
- joint pain and pain (especially in hips, knees, and shoulders)<\/li>
- mobility difficulties<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 Tell your doctor if you notice any of these symptoms.<\/strong>
<\/p>\n\n\n\nDuring HIV treatment, weight gain and increased levels of lipids and glucose in the blood may occur. This is partly related to restored health and lifestyle, but when it comes to blood lipids, there can sometimes be a connection with HIV drugs. The doctor will perform tests to find such changes.
<\/p>\n\n\n\n
Reporting of side effects<\/em><\/p>\n\n\n\nIf you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n
5. How to store Biktarvy<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton and can after {EXP}. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Store in the original package. Moisture sensitive. Close the jar tightly. Do not use if the seal on the jar is broken or missing.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances are<\/strong> biktegravir, emtricitabine, and tenofoviralafenamide. Each Biktarvy tablet contains biktegravir sodium equivalent to 50 mg biktegravir, 200 mg emtricitabine, and tenofoviralafenamide fumarate equivalent to 25 mg tenofoviralafenamide.
<\/p>\n\n\n\nOther ingredients are<\/strong><\/p>\n\n\n\nTablet core<\/em><\/p>\n\n\n\nMicrocrystalline cellulose, croscarmellose sodium, magnesium stearate
<\/p>\n\n\n\n
Film coating<\/em><\/p>\n\n\n\nPolyvinyl alcohol, titanium dioxide (E171), macrogol, talc, red iron oxide (E172), black iron oxide (E172).<\/p>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Biktarvy film-coated tablets are purple-brown, capsule-shaped tablets. Embossed on one side with “GSI” and “9883” on the other side.<\/p>\n\n\n\n
Biktarview is available in jars with 30 tablets and in packages consisting of 3 jars, each with 30 tablets.<\/p>\n\n\n\n
The jar contains a desiccant in the form of silica gel which must be stored in the jar to protect the tablets. The desiccant (silica gel) is in a separate sachet or container and should not be swallowed.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/strong><\/p>\n\n\n\nGilead Sciences Ireland UC<\/p>\n\n\n\n
Carrigtohill<\/p>\n\n\n\n
County Cork, T45 DP77<\/p>\n\n\n\n
Ireland
<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nGilead Sciences Ireland UC<\/p>\n\n\n\n
IDA Business & Technology Park<\/p>\n\n\n\n
Carrigtohill<\/p>\n\n\n\n
County Cork<\/p>\n\n\n\n
Ireland
<\/p>\n","protected":false},"excerpt":{"rendered":"
Biktarvy is a combination tablet for the treatment of human immunodeficiency virus-1 infection ( HIV -1 ) in adults.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8824,8827,8828,8830,3398,4328,5872,5877,8826,8831,8832,8825,8829,4318,8833],"class_list":["post-6083","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-biktarvy","tag-biktarvy-tablet","tag-biktegravir","tag-biktegravir-tablet","tag-emtricitabine","tag-emtricitabine-tablet","tag-tenofoviralafenamide","tag-tenofoviralafenamide-tablet","tag-what-biktarvy-is-used-for","tag-what-biktegravir-is-used-for","tag-what-emtricitabine-is-used-for","tag-what-is-biktarvy","tag-what-is-biktegravir","tag-what-is-emtricitabine","tag-what-tenofoviralafenamide-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6083","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6083"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6083\/revisions"}],"predecessor-version":[{"id":12007,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6083\/revisions\/12007"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6083"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6083"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6083"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}