{"id":6081,"date":"2020-12-31T15:09:19","date_gmt":"2020-12-31T15:09:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6081"},"modified":"2021-07-02T06:47:00","modified_gmt":"2021-07-02T06:47:00","slug":"bicavera-1-5-glucose-1-25mmol-l-calcium","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bicavera-1-5-glucose-1-25mmol-l-calcium\/","title":{"rendered":"BicaVera 1.5% Glucose, 1.25mmol \/ l Calcium uses, dose and side effects"},"content":{"rendered":"\n<p>\n\nperitoneal dialysis fluid&nbsp;<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What bicaVera is and what it is used for<\/h2>\n\n\n\n<p>bicaVera is used for purifying the blood via the peritoneum (&nbsp;peritoneum&nbsp;) in patients with&nbsp;chronic&nbsp;renal failure.&nbsp;This type of blood purification is called&nbsp;peritoneal dialysis.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using bicaVera<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use bicaVera 1.5% Glucose, 1.25 mmol \/ l Calcium<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have very low&nbsp;<strong>potassium levels<\/strong>&nbsp;in your blood<\/li><li>if you have very low&nbsp;<strong>calcium levels<\/strong>&nbsp;in your blood<br><\/li><\/ul>\n\n\n\n<p><strong>Peritoneal dialysis treatment should not be started at<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes in the abdomen or in the abdominal cavity that include:<ul><li>injuries or after surgery,<\/li><li>severe burns<\/li><li>widespread&nbsp;inflammation&nbsp;is of the skin<\/li><li>peritonitis<\/li><li>non-healing exuding wounds<\/li><li>umbilical, groin, or diaphragmatic hernia<\/li><li>the tumor&nbsp;is in the abdomen or intestines<\/li><\/ul><\/li><li>inflammatory bowel diseases<\/li><li>tarmvred<\/li><li>if you have a lung disease, especially&nbsp;pneumonia<\/li><li>blood poisoning caused by bacteria<\/li><li>extremely high-fat levels in the blood<\/li><li>cases of urinary intoxication in the blood that cannot be treated with&nbsp;peritoneal dialysis<\/li><li>severe malnutrition and weight loss especially when adequate protein intake through food is not possible<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Tell your doctor immediately<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if your&nbsp;<strong>electrolyte content (salinity) decreases sharply<\/strong>&nbsp;due to&nbsp;<strong>vomiting and \/ or diarrhea<\/strong><\/li><li>if you have&nbsp;an overproduction of parathyroid hormone&nbsp;or have&nbsp;low calcium levels in your blood.&nbsp;It may be necessary to use phosphate binders that contain&nbsp;calcium&nbsp;and \/ or&nbsp;vitamin&nbsp;D or to use a&nbsp;peritoneal dialysis fluid&nbsp;with a higher calcium concentration.<\/li><li>if you have an&nbsp;<strong>inflammation&nbsp;of the abdominal cavity<\/strong>&nbsp;.&nbsp;This is characterized by cloudy discharge, abdominal pain, fever, general malaise or, in very rare cases, sepsis.&nbsp;<br>The drainage bag with the cloudy dialysate should be taken to your doctor.<\/li><li>if you have&nbsp;<strong>polycystic kidneys<\/strong>&nbsp;(hereditary kidney disease)<\/li><li>if you have&nbsp;<strong>severe abdominal pain, swollen abdomen, or vomiting<\/strong>.&nbsp;This can be a sign of a condition called encapsulating&nbsp;peritoneal&nbsp;sclerosis, a complication of peritoneal dialysis treatment that can be fatal.<\/li><\/ul>\n\n\n\n<p>Peritoneal dialysis&nbsp;can lead to&nbsp;<strong>loss of&nbsp;protein&nbsp;you<\/strong>&nbsp;and the&nbsp;<strong>water-soluble&nbsp;vitamins you<\/strong>&nbsp;.&nbsp;To avoid nutritional deficiencies, a good diet or nutritional supplement is recommended.<br><\/p>\n\n\n\n<p>Electrolyte&nbsp;(salt) balance, blood levels, kidney function, body weight and nutritional status will be checked by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and bicaVera<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Peritoneal dialysis&nbsp;may affect the effectiveness of other medicines and your doctor may need to change their&nbsp;dosage.&nbsp;This is especially important for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Cardiac medicine<\/strong>, eg&nbsp;digitalis.&nbsp;<br>Your doctor will check your blood potassium level and take the necessary action if necessary.<\/li><li><strong>Medicines that affect calcium levels<\/strong>, such as those that contain&nbsp;calcium&nbsp;or&nbsp;vitamin&nbsp;D.<\/li><li><strong>Medicines that increase urine production<\/strong>, such as&nbsp;diuretics.<\/li><li><strong>Medications<\/strong>&nbsp;are taken by mouth and&nbsp;<strong>lowering blood sugar<\/strong>&nbsp;or&nbsp;insulin.&nbsp;Your blood sugar level should be measured regularly.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p>There is insufficient information from the use of bicaVera during pregnancy or breast-feeding.&nbsp;If you are pregnant or breast-feeding, only use bicaVera if your doctor considers it absolutely necessary.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>bicaVera has no or negligible effect on the ability to drive and use machines.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use bicaVera<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Your doctor will adapt the method, how long and how often the&nbsp;dialysis&nbsp;should take place and what volume is needed and how long the solution should be kept in the abdominal cavity, to your needs.<\/p>\n\n\n\n<p>If you experience tension in the abdominal cavity, your doctor may reduce the volume of dialysis.<br><\/p>\n\n\n\n<p><strong>Continuous&nbsp;outpatient&nbsp;peritoneal dialysis&nbsp;(&nbsp;CAPD&nbsp;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults<\/strong>: The usual&nbsp;dose&nbsp;is 2000 &#8211; 2500 ml dialysis fluid four times a day, depending on body weight and kidney function.&nbsp;<br>The solution is kept in the abdominal cavity for 2-10 hours, after which it is emptied.<\/li><li><strong>Children<\/strong>: The doctor adjusts the volume of dialysis fluid needed depending on the child&#8217;s tolerance, age, and body surface area.&nbsp;<br>The recommended starting dose is 600-800 ml \/ m&nbsp;<sup>2<\/sup>&nbsp;&nbsp;body surface area (up to 1000 ml \/ m&nbsp;<sup>2<\/sup>&nbsp;body surface area overnight) four times daily.<\/li><\/ul>\n\n\n\n<p><strong>Automatic&nbsp;peritoneal&nbsp;dialysis&nbsp;(APD)<\/strong><\/p>\n\n\n\n<p>bicaVera sleep safe should be used for this.&nbsp;Bag changes are automatically checked by the machine during the night.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults: The<\/strong>&nbsp;usual&nbsp;dose&nbsp;is 2000 ml (maximum 3000 ml) per treatment period with 3-10 treatment periods during the night within a time period of 8-10 hours and one or two treatment periods during the day.<\/li><li><strong>Children: The<\/strong>&nbsp;volume per treatment period should be 800-1000 ml \/ m&nbsp;<sup>2<\/sup>&nbsp;(up to 1400 ml \/ m&nbsp;<sup>2<\/sup>&nbsp;) body surface area with 5-10 treatment periods overnight.<\/li><\/ul>\n\n\n\n<p>Use&nbsp;th<strong>e only<\/strong>&nbsp;bicaVera&nbsp;<strong>in the abdominal cavity<\/strong>.<br><\/p>\n\n\n\n<p>Only use bicaVera if the solution is ready and the packaging is undamaged.<br><\/p>\n\n\n\n<p>bicaVera is supplied in a double-chamber bag.&nbsp;The solutions in the two chambers must be mixed before use according to the instructions.<br><\/p>\n\n\n\n<p><strong>Handling instructions<\/strong><br><\/p>\n\n\n\n<p><em>Instructions for use for the stay safe system for&nbsp;continuous&nbsp;outpatient&nbsp;peritoneal dialysis&nbsp;(&nbsp;CAPD&nbsp;)<\/em><\/p>\n\n\n\n<p>The liquid bag must first be warmed to body temperature.&nbsp;The heating must be done with a dedicated hotplate.&nbsp;The heating time for a 2000 ml bag with an initial temperature of 22 \u00baC is about 2 hours (120 minutes).&nbsp;More detailed information can be found in the operating instructions for the hotplate.&nbsp;Microwave ovens must not be used for heating due to the risk of local overheating.&nbsp;After heating the liquid bag, the bag change can begin.<br><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li><strong>Preparation&nbsp;of the solution<\/strong><ul><li>Check the heated liquid bag (label, expiration date, that the liquid is ready, that the bag and outer casing are intact and that the weld is intact).<\/li><li>Place the bag on a firm surface.<\/li><li>Open the outer casing of the bag and open the packaging for the disinfection sleeve.<\/li><li>Wash hands with a disinfectant soap solution.<\/li><li>Roll up the bag, which is located on the outer cover, from one of the sides until the middle joint opens.&nbsp;The solutions in the two chambers are mixed automatically.<\/li><li>Then roll up the bag from the top edge until the joint in the lower triangle is completely open.<\/li><li>Check that all joints are fully open.<\/li><li>Check that the solution is ready and that the bag is not leaking.<\/li><\/ul><\/li><li><strong>Preparation for bag change<\/strong><ul><li>Hang the liquid bag at the top of the drip stand, roll up the hose from the liquid bag and place the flow selector in the holder.&nbsp;Roll up the hose to the drainage bag and hang the drainage bag at the bottom of the drip stand.<\/li><li>Place the catheter extension in one of the two holes in the holder.<\/li><li>Place the new disinfection sleeve in the second hole in the holder.<\/li><li>Disinfect&nbsp;your hands and remove the plug from the flow selector.<\/li><li>Connect the catheter extension to the flow selector.<\/li><\/ul><\/li><li><strong>Outflow<\/strong><ul><li>Open the clamp on the catheter extension, position &#8220;\u25cf&#8221;.&nbsp;The outflow begins.<\/li><\/ul><\/li><li><strong>Flushing<\/strong><ul><li>After the outflow is completed, turn the flow selector clockwise to the &#8220;\u25cf\u25cf&#8221; position.&nbsp;Flushing takes place from liquid bag to drainage bag (approx. 5 sec).<\/li><\/ul><\/li><li><strong>Inflow<\/strong><ul><li><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20150304000078#\" rel=\"noopener\"><\/a>Start inflow by turning the flow selector to position&nbsp;<\/li><\/ul><\/li><li><strong>Security measure<\/strong><ul><li>Turn the flow selector to the &#8220;\u25cf\u25cf\u25cf\u25cf&#8221; position, the catheter extension is then closed automatically by inserting a PIN into the catheter extension coupling.&nbsp;Close the clamp on the catheter extension.<\/li><\/ul><\/li><li><strong>Disconnection<\/strong><ul><li>Remove the protective plug from the new disinfection sleeve and screw it onto the old disinfection sleeve.<\/li><li>Unscrew the catheter extension from the flow selector and screw the catheter extension onto the new disinfection sleeve.<\/li><\/ul><\/li><li><strong>Closing the flow selector<\/strong><ul><li>Close the flow selector with the open end of the protective plug of the used disinfection sleeve, which is located in one of the two holes on the holder.<\/li><\/ul><\/li><li><strong>Check the weight of the drained dialysis fluid<\/strong>&nbsp;and that it is not cloudy.&nbsp;The clear liquid is discarded.<br><\/li><\/ol>\n\n\n\n<p><em>Instructions for use for the sleep safe system for automatic&nbsp;peritoneal dialysis&nbsp;(APD)<\/em><\/p>\n\n\n\n<p>During automatic&nbsp;peritoneal dialysis&nbsp;(APD), the fluid is automatically heated by the sleep safe machine.<br><\/p>\n\n\n\n<p><strong>3000 ml sleep safe system:<\/strong><\/p>\n\n\n\n<p><strong>1.&nbsp;Preparation&nbsp;of the solution:&nbsp;<\/strong>&nbsp;<strong>see the stay safe system.<\/strong><\/p>\n\n\n\n<p><strong>2. Roll up the hose from the bag.<\/strong><\/p>\n\n\n\n<p><strong>3. Remove the protective plug.&nbsp;<br>4. Insert the coupling into the free compartment of the sleep safe machine.<\/strong><\/p>\n\n\n\n<p><strong>5. The bag is now ready to use together with the sleep safe set.<\/strong><br><\/p>\n\n\n\n<p><strong>5000 ml sleep safe system:<\/strong><\/p>\n\n\n\n<p><strong>1.&nbsp;Preparation&nbsp;of the solution<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Check the liquid bag before use (label, expiration date, that the liquid is ready, that the bag and outer casing are intact and that the welds are intact).<\/li><li>Place the bag on a firm surface.<\/li><li>Open the outer casing of the bag.<\/li><li>Wash hands with a disinfectant soap solution.<\/li><li>Unfold the middle seam and the attachment.<\/li><li>Roll up the bag (located on the outer casing), from the diagonal to the coupling.&nbsp;The middle seam will open.<\/li><li>Continue until the weld seam on the small chamber also opens.<\/li><li>Check that all weld seams are fully open.<\/li><li>Check that the solution is ready and that the bag is not leaking.<\/li><\/ul>\n\n\n\n<p><strong>2<\/strong>&nbsp;&#8211;&nbsp;<strong>5: see 3000 ml sleep safe system<\/strong><br><\/p>\n\n\n\n<p>Each bicaVera bag is for single use only and unused liquid must be discarded.<br><\/p>\n\n\n\n<p>After adapted training in handling, bicaVera can be used independently at home.&nbsp;Be sure to follow all the procedures you learned during the workout.&nbsp;Aseptic technique must be maintained during the bag change to minimize the risk of&nbsp;infection.<br><\/p>\n\n\n\n<p>Always check if the dialysate in the drainage bag is cloudy, see section 2 Warnings and precautions \u201d.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more bicaVera than you should<\/h2>\n\n\n\n<p>If too much dialysis solution is infused, it can easily be emptied into the drainage bag.&nbsp;However, if bag changes have been made too often, you should contact your doctor as this may lead to dehydration and \/ or imbalance in electrolyte levels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use bicaVera<\/h2>\n\n\n\n<p>Try to keep the prescribed total daily dose of the dialysis volume to avoid life-threatening consequences.&nbsp;Contact your doctor if you are unsure.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, bicaVera can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur as a result of peritoneal dialysis treatment:<br><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>peritonitis with signs of cloudy dialysate, abdominal pain, fever, general malaise, or, in very rare cases, sepsis.&nbsp;<br>The drainage bag with the cloudy dialysate should be taken to your doctor.<\/li><li>inflammation&nbsp;of the skin around the dialysis catheter (at the starting point and along the tunnel).&nbsp;Signs of this are&nbsp;redness, swelling, pain, fluid or scabs<\/li><li>hernia&nbsp;in the abdominal wall<\/li><\/ul>\n\n\n\n<p>At the slightest sign of these&nbsp;side effects, contact your doctor immediately.<br><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;due to the treatment are:<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>problems with inflow and outflow of the dialysis solution<\/li><li>dilated abdomen and feeling of bloating<\/li><li>pain in the shoulders<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea<\/li><li>constipation<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>difficulty breathing due to the elevation of the diaphragm.<\/li><li>Encapsulating&nbsp;peritoneal&nbsp;sclerosis, possible symptoms may be abdominal pain, swollen abdomen, or vomiting.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur when using bicaVera:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>potassium deficiency<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high blood sugar levels<\/li><li>elevated blood fat levels<\/li><li>weight gain<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>calcium deficiency<\/li><li>too low levels of body fluid, which can result in rapid weight loss<\/li><li>low&nbsp;blood pressure<\/li><li>increased&nbsp;heart rate<\/li><li>too high levels of body fluid which can result in rapid weight gain<\/li><li>water in&nbsp;tissue&nbsp;and lungs<\/li><li>high&nbsp;blood pressure<\/li><li>breathing difficulties<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>overactivity of the parathyroid gland, which can cause disorders in bone metabolism<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store bicaVera<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bag and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>bica&nbsp;<em>Vera stays safe \/ sleep safe<\/em>: Store at least 4 \u00b0 C.<\/p>\n\n\n\n<p>bica&nbsp;<em>Vera&nbsp;<\/em>&nbsp;<em>sleep safe combo<\/em>: Store at 5 \u00b0 C &#8211; 30 \u00b0 C<br><\/p>\n\n\n\n<p>The reconstituted solution should be used immediately and within a maximum of 24 hours after&nbsp;mixing.<\/p>\n\n\n\n<p>May only be used if the solution is ready and the packaging is undamaged.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances in one liter of reconstituted&nbsp;peritoneal dialysis fluid&nbsp;are:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Calcium chloride dihydrate<\/strong><\/td><td><strong>0.1838 g<\/strong><\/td><\/tr><tr><td>Sodium chloride<\/td><td>5,786 g<\/td><\/tr><tr><td>Sodium bicarbonate<\/td><td>2,940 g<\/td><\/tr><tr><td>Magnesium chloride hexahydrate<\/td><td>0.1017 g<\/td><\/tr><tr><td>Glucose monohydrate<\/td><td>16.5 g<\/td><\/tr><tr><td>(equivalent to 15.0 g&nbsp;glucose&nbsp;)<\/td><td><br><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>This corresponds to an electrolyte content of:<\/p>\n\n\n\n<p>1.25 mmol \/ l&nbsp;calcium&nbsp;, 134 mmol \/ l&nbsp;sodium&nbsp;, 0.5 mmol \/ l&nbsp;magnesium&nbsp;, 103.5 mmol \/ l chloride, 34 mmol \/ l bicarbonate and 83.25 mmol \/ l&nbsp;glucose&nbsp;.<br><\/p>\n\n\n\n<p>The other ingredients in bicaVera are water for injections,&nbsp;hydrochloric acid, sodium hydroxide, and&nbsp;carbon dioxide.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The solution is clear and colorless.<\/p>\n\n\n\n<p>The theoretical osmolarity in a ready-mixed solution is 357 mosm \/ l and the&nbsp;pH&nbsp;is about 7.4.<br><\/p>\n\n\n\n<p>bicaVera is supplied in a double-chamber bag.&nbsp;One chamber contains the alkaline bicarbonate solution, the other chamber contains the acidic glucose-based electrolyte solution in a ratio of 1: 1.<br><\/p>\n\n\n\n<p>bicaVera is a&nbsp;peritoneal dialysis fluid&nbsp;and is supplied in the following packages and systems:<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong><em>stay safe<\/em><\/strong>4 bags of 2000 ml4 bags of 2500 ml<\/td><td><strong><em>sleep safe<\/em><\/strong>4 bags of 3000 ml2 bags of 5000 ml<\/td><\/tr><tr><td><strong><em>sleep safe combo<\/em><\/strong>2 bags of 5000 ml + disinfection sleeve +&nbsp;<em>sleep safe<\/em>&nbsp;Set Plus<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Fresenius Medical Care Deutschland GmbH, Else-Kr\u00f6ner-Strasse 1, 61352 Bad Homburg vdH, Germany<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>bica&nbsp;<em>Vera stay&nbsp;<\/em>&nbsp;<em>safe \/ sleep safe<\/em>&nbsp;:<\/p>\n\n\n\n<p>Fresenius Medical Care Deutschland GmbH, Frankfurter Strasse 6-8, 66606 St.&nbsp;Wendel, Germany<br><\/p>\n\n\n\n<p>bica&nbsp;<em>Vera&nbsp;<\/em>&nbsp;<em>sleep&nbsp;<\/em><em>&nbsp;safe combo<\/em>&nbsp;:<\/p>\n\n\n\n<p>Fresenius Medical Care Deutschland GmbH, Else-Kr\u00f6ner-Stra\u00dfe 1, 61352 Bad Homburg vdH, Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>bicaVera is used for purifying the blood via the peritoneum ( peritoneum ) in patients with chronic renal failure. This type of blood purification is called peritoneal dialysis.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8836,8841,8839,3276,8840,8838,8837],"class_list":["post-6081","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-bicavera","tag-bicavera-dose","tag-bicavera-side-effects","tag-peritoneal-dialysis-fluid","tag-side-effects-of-bicavera","tag-what-bicavera-is-used-for","tag-what-is-bicavera"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6081"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6081\/revisions"}],"predecessor-version":[{"id":12008,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6081\/revisions\/12008"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6081"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}