{"id":6079,"date":"2020-12-31T15:06:37","date_gmt":"2020-12-31T15:06:37","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6079"},"modified":"2021-07-02T06:47:09","modified_gmt":"2021-07-02T06:47:09","slug":"bicalutamide-sandoz","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bicalutamide-sandoz\/","title":{"rendered":"Bicalutamide Sandoz &#8211; Bicalutamide uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n50 mg&nbsp;film-coated tablets&nbsp;<br>bicalutamide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Bicalutamide Sandoz is and what it is used for<\/h2>\n\n\n\n<p>Bicalutamide Sandoz belongs to a group of medicines called antiandrogens.&nbsp;It affects the way male sex hormones work.<br><\/p>\n\n\n\n<p>Bicalutamide Sandoz is used in treating prostate cancer.&nbsp;Bicalutamide Sandoz is used either as<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>monotherapy<\/strong>&nbsp;in tumor stages called \u201clocally advanced\u201d or as<\/li><li><strong>combination therapy<\/strong>&nbsp;for tumor stages called \u201cadvanced\u201d along with other treatments such as surgical castration or drugs that reduce the levels of&nbsp;androgenic your body.<\/li><\/ul>\n\n\n\n<p>Bicalutamide contained in Bicalutamide Sandoz may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Bicalutamide Sandoz<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Bicalutamide Sandoz<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to bicalutamide or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are a woman, child, or youth<\/li><li>if you are taking medicines containing terfenadine, astemizole, or cisapride (see \u201cOther medicines and Bicalutamide Sandoz\u201d below).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Talk to your doctor or pharmacist before taking Bicalutamide Sandoz<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have any liver problems.&nbsp;The levels of bicalutamide in your blood could increase.&nbsp;It is possible that your liver function will be tested at regular intervals.<\/li><li>if you have&nbsp;diabetes.<\/li><li>if you have cardiovascular disease including cardiac arrhythmias (&nbsp;arrhythmia&nbsp;), or if you are taking medication for this.&nbsp;The risk of suffering from heart rhythm disorders may be increased when taking Bicalutamide Sandoz.<\/li><li>If you are taking Bicalutamide Sandoz, you and\/or your partner should use contraception while taking Bicalutamide Sandoz and for 130 days after stopping Bicalutamide Sandoz.&nbsp;Talk to your doctor if you have any questions about contraception.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Bicalutamide Sandoz<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;It is especially important to mention if you are taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>terfenadine or astemizole (for hay fever or&nbsp;allergies&nbsp;) or cisapride (for stomach problems).&nbsp;See \u201cDo not take Bicalutamide Sandoz\u201d<\/li><li>ciclosporin (used to&nbsp;suppress the&nbsp;immune system, to prevent and treat the rejection of a transplanted organ or&nbsp;bone marrow&nbsp;)<\/li><li>calcium channel blockers (for the treatment of high&nbsp;blood pressure&nbsp;or certain heart problems)<\/li><li>cimetidine (for the treatment of&nbsp;stomach ulcers&nbsp;)<\/li><li>ketoconazole&nbsp;(used to treat fungal infections of the skin and nails)<\/li><li>medicines to prevent blood clots and blood-thinning medicines such as&nbsp;warfarin.&nbsp;Your doctor may take blood samples before and during your treatment with Bicalutamide Sandoz.<\/li><\/ul>\n\n\n\n<p>Bicalutamide Sandoz may affect some other medicines used to treat heart rhythm disorders (eg&nbsp;quinidine,&nbsp;procainamide,&nbsp;amiodarone,&nbsp;and sotalol) or may increase the risk of heart rhythm disorders when used with other medicines (eg&nbsp;methadone&nbsp;(used for pain and in the treatment of drug addiction), moxifloxacin (an&nbsp;antibiotic&nbsp;), antipsychotics (used for severe mental illness).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Bicalutamide Sandoz should not be used by women.<\/p>\n\n\n\n<p>Bicalutamide Sandoz can lead to decreased fertility or infertility in men during menopause.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>These tablets can make you dizzy or drowsy.&nbsp;If you are affected in this way, do not drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bicalutamide Sandoz contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<p><strong>Bicalutamide Sandoz contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per dose unit, ie essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Bicalutamide Sandoz<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Depending on your condition, the usual&nbsp;dose is&nbsp;one 50 mg tablet daily (&nbsp;combination therapy&nbsp;), or three 50 mg tablets once daily (&nbsp;monotherapy&nbsp;).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the tablets whole with a glass of water.<\/li><li>You can take these tablets with or without food.<\/li><li>Try to take the tablets at the same time each day.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Bicalutamide Sandoz<\/h2>\n\n\n\n<p>If you forget to take your medicine, take the tablet as soon as you remember and then take the next&nbsp;dose&nbsp;at the usual time.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Bicalutamide Sandoz<\/h2>\n\n\n\n<p>Do not stop taking your medicine even if you feel well unless your doctor has told you to stop taking it.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Serious side effects:<\/strong><\/p>\n\n\n\n<p><strong>You should contact a doctor immediately if you notice any of the following serious&nbsp;side effects.<\/strong><br><\/p>\n\n\n\n<p><strong>Common serious&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>yellowing of the skin or whites of the eyes due to liver problems or, in rare cases (may affect up to 1 in 1,000 patients), liver failure.<\/li><\/ul>\n\n\n\n<p><strong>The common serious&nbsp;side effect&nbsp;is<\/strong>&nbsp;(may affect up to 1 in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the severe&nbsp;allergic reaction&nbsp;that causes swelling of the face or throat, or severe&nbsp;itching of the skin with&nbsp;hives.<\/li><li>severe shortness of breath or sudden worsening of shortness of breath, possibly with cough or fever.&nbsp;Some patients taking Bicalutamide Sandoz develop an&nbsp;inflammation&nbsp;of the lungs called interstitial lung disease.<\/li><\/ul>\n\n\n\n<p><strong>Has&nbsp;<\/strong><strong>been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes (&nbsp;QT&nbsp;prolongation) on&nbsp;ECG&nbsp;(&nbsp;electrocardiogram&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>Other side effects:<\/strong><\/p>\n\n\n\n<p>The frequency of some&nbsp;side effects&nbsp;depends on whether Bicalutamide Sandoz is used in&nbsp;monotherapy&nbsp;or&nbsp;combination therapy.<br><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effect&nbsp;is<\/strong>&nbsp;(can occur in more than 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>tender or enlarged breasts<\/li><li>weakness<\/li><li>skin rash &#8211; very common in&nbsp;monotherapy&nbsp;but common (may occur in up to 1 patient in 10) in&nbsp;combination therapy.<\/li><li>decreased number of&nbsp;red blood cells&nbsp;which can make the skin pale and cause weakness or shortness of breath.<\/li><\/ul>\n\n\n\n<p>Very common in&nbsp;combination therapy&nbsp;but common in&nbsp;monotherapy&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hot flashes<\/li><li>dizziness<\/li><li>abdominal pain, constipation, nausea<\/li><li>edema&nbsp;(fluid swelling)<\/li><li>blood in the urine.<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>loss of appetite<\/li><li>decreased sex drive<\/li><li>difficulty getting&nbsp;an erection&nbsp;(&nbsp;erectile dysfunction&nbsp;)<\/li><li>Depression<\/li><li>drowsiness<\/li><li>somnolence<\/li><li>digestive problems, gases<\/li><li>hair loss, heavy hair growth on the body<\/li><li>dry skin,&nbsp;itching<\/li><li>weight gain<\/li><li>blood tests that show changes in liver function<\/li><li>heart attack,&nbsp;heart failure<\/li><li>chest pain.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;<\/strong>&nbsp;<strong>side effects&nbsp;are<\/strong>&nbsp;&nbsp;(may affect up to 1 in 1000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased sensitivity of the skin to sunlight.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Bicalutamide Sandoz<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and on the blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is bicalutamide.&nbsp;Each film-coated tablet contains 50 mg of bicalutamide.<\/li><li>The other ingredients are:&nbsp;&nbsp;<br>Tablet core:&nbsp;Lactose monohydrate, sodium&nbsp;starch glycolate&nbsp;type A, povidone K 30 (E1201), corn starch, and magnesium stearate (E572).&nbsp;<br>Film coating: Methylcellulose, titanium dioxide (E171) and triacetin (E1518).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Round and white film-coated tablet, with a diameter of about 7 mm.<\/p>\n\n\n\n<p>Packs of PVC \/ Aclar \/\/ Al blister cards may contain 20, 28, 30, 50, 56, 60, 84, 90, 98 or 100 film-coated tablets.<\/p>\n\n\n\n<p>The packages with one-piece perforated PVC \/ Aclar \/\/ Al blister cards can contain 50 or 100 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Lek Pharmaceuticals dd, Verov\u015bkova 57, 1526 Ljubljana, Slovenia<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bicalutamide Sandoz belongs to a group of medicines called antiandrogens. It affects the way male sex hormones work.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[7693,8844,8846,7695,7696,8848,8843,8847,7694,8845],"class_list":["post-6079","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-bicalutamide","tag-bicalutamide-sandoz","tag-bicalutamide-sandoz-tablet","tag-bicalutamide-side-effects","tag-bicalutamide-tablet","tag-side-effects-of-bicalutamide-sandoz","tag-what-bicalutamide-is-used-for","tag-what-bicalutamide-sandoz-is-used-for","tag-what-is-bicalutamide","tag-what-is-bicalutamide-sandoz"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6079","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6079"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6079\/revisions"}],"predecessor-version":[{"id":12009,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6079\/revisions\/12009"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6079"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6079"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}