{"id":6046,"date":"2020-12-30T14:43:30","date_gmt":"2020-12-30T14:43:30","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6046"},"modified":"2021-07-02T06:48:08","modified_gmt":"2021-07-02T06:48:08","slug":"bezalip","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bezalip\/","title":{"rendered":"Bezalip &#8211; Bezafibrate uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n200 mg&nbsp;film-coated tablets&nbsp;<br>bezafibrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Bezalip is and what it is used for<\/h2>\n\n\n\n<p>Bezalip belongs to a group of medicines called fibrates.&nbsp;These drugs are used to lower the fat content (&nbsp;lipids&nbsp;) in the blood.&nbsp;For example, fats called&nbsp;triglycerides are.<br><\/p>\n\n\n\n<p>High levels of&nbsp;LDL&nbsp;&#8211;&nbsp;cholesterol,&nbsp;and&nbsp;triglycerides&nbsp;increase the risk of atherosclerosis, angina, and heart attack, especially in combination with other risk factors (eg if you smoke, have high&nbsp;blood pressure,&nbsp;or&nbsp;diabetes&nbsp;).<br><\/p>\n\n\n\n<p>Bezalip is used with diet and other non-medical treatments, such as exercise and weight loss, to lower blood fat levels.<br><\/p>\n\n\n\n<p>Bezafibrate contained in Bezalip may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Bezalip<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Bezalip:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to bezafibrate, other fibrates, or any of the other ingredients of this medicine (listed in section 6),<\/li><li>if you have severe liver or kidney disease,<\/li><li>if you are being treated with&nbsp;dialysis,<\/li><li>if you have had skin reactions due to sunlight when you have previously been treated with fibrates (&nbsp;cholesterol-&nbsp;and triglyceride-lowering drugs).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Bezalip.&nbsp;This is especially true if you have liver, kidney or gallstone disease.<br><\/p>\n\n\n\n<p>Concomitant use of Bezalip and another lipid-lowering drug called statins (eg&nbsp;simvastatin&nbsp;or atorvastatin) may increase the risk of muscle damage.&nbsp;Talk to your doctor if you are taking Bezalip and statins at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Bezalip<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.&nbsp;The effect of Bezalip can be affected if Bezalip and certain other medicines are taken at the same time.<\/p>\n\n\n\n<p>This is especially true if Bezalip is used concomitantly with statins and cholestyramine (&nbsp;cholesterol-lowering drugs).&nbsp;If Bezalip and cholestyramine are used at the same time, the drugs should be taken at least 2 hours apart.<br><\/p>\n\n\n\n<p>Other drugs that can affect the treatment effect are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sulphonylureas and&nbsp;insulin&nbsp;(used for&nbsp;diabetes&nbsp;),<\/li><li>warfarin&nbsp;(an agent that inhibits the ability of the blood to clot),<\/li><li>cyclosporine (an agent that suppresses the immune system).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is limited experience of use during pregnancy.&nbsp;Bezalip is not recommended during pregnancy as safety has not yet been established.<br><\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Lack of experience.&nbsp;Mothers treated with Bezalip should not breast-feed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>In less common cases, dizziness, fatigue, or muscle weakness appear as a side effect, which can impair the ability to drive and use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bezalip contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie it is essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Bezalip<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Dose&nbsp;one is determined by the doctor who adjusts it individually for you.&nbsp;The recommended&nbsp;dose&nbsp;is 1 tablet 3 times daily.&nbsp;The tablet is suitably taken with food and should be swallowed whole.<br><\/p>\n\n\n\n<p><strong>Use for children<\/strong><\/p>\n\n\n\n<p>The use of Bezalip in children is not recommended as the efficacy and safety of children have not been established.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Bezalip<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop taking Bezalip and contact a doctor as soon as possible:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you get unexplained muscle pain, muscle cramps or muscle weakness.&nbsp;(This may be a sign of a rare side effect called&nbsp;rhabdomyolysis&nbsp;that may affect up to 1 in 1,000 people.)<\/li><li>if you get severe skin reactions, such as&nbsp;Stevens-Johnson syndrome&nbsp;(an extremely severe&nbsp;allergic reaction&nbsp;with skin rash usually in the form of blisters or sores in the oral cavity and eyes and other mucous membranes such as the genitals) or&nbsp;toxic epidermal necrolysis&nbsp;(severe widespread skin damage with dermal and superficial skin mucous membranes).&nbsp;These reactions are very rare.<\/li><\/ul>\n\n\n\n<p><em>Common (may affect more than 1 user in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Disorders of the gastrointestinal tract, such as stomach cramps, acid regurgitation, nausea<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, dizziness<\/li><li>Diarrhea, constipation, vomiting, gas, abdominal pain, decreased appetite<\/li><li>Skin rash,&nbsp;itching, photosensitivity,&nbsp;hives<\/li><li>Liver effects,&nbsp;gallstones,&nbsp;gallstones<\/li><li>Muscle weakness, muscle pain, muscle cramps<\/li><li>Acute&nbsp;renal failure<\/li><li>Impotence<\/li><li>Hypersensitivity reaction<\/li><li>Changed laboratory values<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hair loss<\/li><li>Decreased number of white and\/or&nbsp;red blood cells<\/li><li>Muscle inflammation<\/li><li>Pancreatitis<\/li><li>Disorders of nerve function, loss of sensation, or a stinging sensation in the skin<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reduced&nbsp;platelet count<\/li><li>Lung disease<\/li><\/ul>\n\n\n\n<p><em>No known frequency (cannot be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Depression, insomnia<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Bezalip<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is bezafibrate.&nbsp;One tablet contains 200 mg of bezafibrate.<\/li><li>Other ingredients are:<ul><li>Tablet core: corn starch, pregelatinized&nbsp;starch, microcrystalline cellulose, sodium&nbsp;starch&nbsp;glycolate, anhydrous&nbsp;colloidal&nbsp;silica, magnesium stearate<\/li><li>Tablet coating: Opadry (polyvinyl alcohol, titanium dioxide (dye E171), macrogol, talc).<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>White, round, film-coated tablet marked G6.<\/p>\n\n\n\n<p>Blister pack, 100 tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Cenexi<\/p>\n\n\n\n<p>52, Rue Marcel and Jacques Gaucher<\/p>\n\n\n\n<p>FR-94120 Fontenay-Sous-Bois<\/p>\n\n\n\n<p>France<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bezalip belongs to a group of medicines called fibrates. These drugs are used to lower the fat content ( lipids ) in the blood. For example, fats called triglycerides are.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8870,8872,8880,8882,8884,8874,8873,8883,8871,8881],"class_list":["post-6046","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-bezafibrate","tag-bezafibrate-tablet","tag-bezalip","tag-bezalip-side-effectsf","tag-bezalip-tablet","tag-side-effects-of-bezafibrate","tag-what-bezafibrate-is-used-for","tag-what-bezalip-is-used-for","tag-what-is-bezafibrate","tag-what-is-bezalip"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6046","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6046"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6046\/revisions"}],"predecessor-version":[{"id":12015,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6046\/revisions\/12015"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6046"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6046"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6046"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}