{"id":6028,"date":"2020-12-30T14:32:18","date_gmt":"2020-12-30T14:32:18","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6028"},"modified":"2021-07-03T07:39:18","modified_gmt":"2021-07-03T07:39:18","slug":"betolvex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/betolvex\/","title":{"rendered":"Betolvex &#8211; Cyanocobalamin uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n1 mg film-coated tablets&nbsp;<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">cyanocobalamin<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Betolvex is and what it is used for<\/h2>\n\n\n\n<p>Vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;is a vital&nbsp;vitamin, which is needed for normal cell division, normal blood formation, and the normal function of the nervous system.&nbsp;Lack of&nbsp;vitamin&nbsp;B&nbsp;12&nbsp;can i.a.&nbsp;give anemia&nbsp;pernicious anemia&nbsp;and\/or symptoms of the nervous system, e.g.&nbsp;emotional disturbances.&nbsp;Normally,&nbsp;vitamin&nbsp;B&nbsp;12 is&nbsp;added&nbsp;in small amounts with food.&nbsp;It is absorbed into the body with the help of e.g.&nbsp;gastric&nbsp;hydrochloric acid&nbsp;and a special&nbsp;protein&nbsp;(intrinsic factor) that is formed in the gastric mucosa.&nbsp;If the intake of pure&nbsp;vitamin&nbsp;B&nbsp;12 is&nbsp;increased 100-fold (= 1 tablet Betolvex) can be enough vitamin&nbsp;is absorbed by the body even if the gastrointestinal function is disturbed.<br><\/p>\n\n\n\n<p>Betolvex is given in case of&nbsp;vitamin&nbsp;B&nbsp;<sub>12&nbsp;<\/sub>deficiency&nbsp;and when there is a risk that&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency will occur.<\/p>\n\n\n\n<p>Vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency can, for example, develop if the&nbsp;vitamin&nbsp;cannot be absorbed by the body normally from food.&nbsp;This can be due to a gastrointestinal disease but can also be the result of, for example, a gastric ulcer operation or other bowel operation.&nbsp;Vitamin&nbsp;B&nbsp;12&nbsp;deficiency can also occur if you take certain medicines used in&nbsp;inflammation&nbsp;of the gastrointestinal tract&nbsp;for a long time<strong>.<\/strong><br><\/p>\n\n\n\n<p>You need to talk to a doctor if you do not feel better or if you feel worse.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Betolvex<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Betolvex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to cyanocobalamin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Betolvex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;uptake&nbsp;may be affected by:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>aminoglycoside&nbsp;is (&nbsp;antibiotics&nbsp;)<\/li><li>aminosalicylic acid (&nbsp;antibiotics&nbsp;)<\/li><li>antiepileptics&nbsp;(medicines used to treat&nbsp;epilepsy&nbsp;)<\/li><li>biguanides (medicines used to treat&nbsp;diabetes&nbsp;)<\/li><li>chloramphenicol (&nbsp;antibiotics&nbsp;)<\/li><li>cholestyramine (medicines used to reduce the amount of&nbsp;cholesterol&nbsp;(fat) in the blood)<\/li><li>potassium salts (used to correct potassium deficiency)<\/li><li>methyldopa (medicines used to treat high&nbsp;blood pressure&nbsp;)<\/li><li>gastric acid inhibitors (eg omeprazole and cimetidine)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>No adverse effects on the fetus or breast-feeding infant have been identified.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Betolvex<\/h2>\n\n\n\n<p>Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Dose&nbsp;one should be determined by a doctor, who will adjust it individually for you.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;for adults is 1 tablet daily.&nbsp;At the beginning of treatment, a higher&nbsp;dose is&nbsp;often prescribed.<br><\/p>\n\n\n\n<p>The tablet should preferably be taken on an empty stomach.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Betolvex<\/h2>\n\n\n\n<p>Treatment with&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;must last a lifetime if it is a result of a chronic poor uptake from the intestine.&nbsp;It is important that you do not stop taking the tablets, even if you feel healthy.&nbsp;Eventually, a B&nbsp;<sub>12<\/sub>&nbsp;deficiency develops again.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop taking Betolvex and contact a doctor immediately if you get any of the following symptoms (&nbsp;angioedema&nbsp;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, tongue, or throat<\/li><li>difficulty swallowing<\/li><li>hives&nbsp;and difficulty breathing.<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are rare (affects up to 1 in 1,000 people).<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have also been reported with Betolvex:<br><\/p>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;are<\/strong>&nbsp;(affecting up to 1 1 000)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions, including&nbsp;itching&nbsp;and swelling<\/li><li>Fever<\/li><li>Rash<\/li><li>Hives<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Betolvex<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;dat.\/EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<br><\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is Cyanocobalamin 1 mg (&nbsp;vitamin&nbsp;B&nbsp;12&nbsp;).<\/li><li>The other ingredients are Mannitol, pregelatinized&nbsp;starch&nbsp;, potato starch, microcrystalline cellulose, magnesium stearate, stearic acid.&nbsp;Film coating: Hypromellose, macrogol, titanium dioxide (dye E 171), iron oxide (dye E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The tablet is pink, round with a diameter of 8 mm, marked CCO.<br><\/p>\n\n\n\n<p>Jar: 30, 60, 100 tablets<\/p>\n\n\n\n<p>1,000 tablets (for dose dispensing and hospital use only)<br><\/p>\n\n\n\n<p>Blister: 50 x 1, 98 x 1 tablets (for hospital use only)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Actavis Group hf.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>IS-220 Hafnarfjordur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Piramal Healthcare Ltd, UK<\/p>\n\n\n\n<p>Whalton Road, Morpeth<\/p>\n\n\n\n<p>Northumberland, NE61 3YA<\/p>\n\n\n\n<p>UK<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin B 12 is a vital vitamin, which is needed for normal cell division, normal blood formation, and the normal function of the nervous system. Lack of vitamin B 12 can i.a. give anemia pernicious anemia and\/or symptoms of the nervous system, e.g. emotional disturbances. Normally, vitamin B 12 is added in small amounts with food. It is absorbed into the body with the help of e.g. gastric hydrochloric acid and a special protein (intrinsic factor) that is formed in the gastric mucosa. If the intake of pure vitamin B 12 is increased 100-fold (= 1 tablet Betolvex) can be enough vitamin is absorbed by the body even if the gastrointestinal function is disturbed.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[8949,8951,8937,8939,8953,8948,8952,8941,8950,8938],"class_list":["post-6028","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-betolvex","tag-betolvex-tablet","tag-cyanocobalamin","tag-cyanocobalamin-tablet","tag-side-effects-of-betolvex","tag-side-effects-of-cyanocobalamin","tag-what-betolvex-is-used-for","tag-what-cyanocobalamin-is-used-for","tag-what-is-betolvex","tag-what-is-cyanocobalamin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6028"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6028\/revisions"}],"predecessor-version":[{"id":12053,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6028\/revisions\/12053"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}