{"id":6006,"date":"2020-12-30T14:17:23","date_gmt":"2020-12-30T14:17:23","guid":{"rendered":"https:\/\/zeepedia.com\/?p=6006"},"modified":"2021-07-05T07:32:01","modified_gmt":"2021-07-05T07:32:01","slug":"besremi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/besremi\/","title":{"rendered":"Besremi &#8211; Ropeginterferon alpha-2b uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n250 micrograms \/ 0.5 ml injection&nbsp;solution in prefilled&nbsp;pen&nbsp;<br>ropeginterferon alpha-2b<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Besremi is and what it is used for<\/h2>\n\n\n\n<p>Besremi contains the active substance peginterferon alfa-2b which belongs to a class of medicines called&nbsp;interferons.&nbsp;Interferon&nbsp;is made by your immune system to&nbsp;inhibit the&nbsp;growth of cancer cells.<br><\/p>\n\n\n\n<p>Besremi is the only drug used to treat&nbsp;polycythemia vera&nbsp;in adults.&nbsp;Polycythemia vera is a type of cancer in which the&nbsp;bone marrow&nbsp;produces too many&nbsp;red blood cells&nbsp;,&nbsp;white blood cells&nbsp;and&nbsp;platelets&nbsp;(cells that cause the blood to coagulate).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Besremi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Besremi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ropeginterferon alfa-2b or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have thyroid disease that is not controlled by medication.<\/li><li>if you have or have had severe mental disorders (eg depression or suicidal ideation or if you have attempted suicide).<\/li><li>if you have or have had severe heart problems (eg heart attack or&nbsp;stroke&nbsp;).<\/li><li>if you have or have had an&nbsp;autoimmune&nbsp;disease (eg&nbsp;rheumatoid arthritis&nbsp;,&nbsp;psoriasis&nbsp;or&nbsp;inflammatory&nbsp;bowel disease).<\/li><li>if you have had an organ transplant and are taking medicines that suppress your immune system.<\/li><li>if you are taking telbivudine (a medicine used to treat&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;).<\/li><li>if you have advanced and uncontrolled liver disease.<\/li><li>if you have severe kidney disease (your kidney function is lower than 15% of normal function)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before using Besremi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have thyroid disease.<\/li><li>if you have&nbsp;diabetes&nbsp;or high&nbsp;blood pressure&nbsp;&#8211; your doctor may have you have an eye examination.<\/li><li>if you have liver problems &#8211; you will have to take blood samples regularly to check how your liver is working if you receive long-term treatment with Besremi.<\/li><li>if you have kidney problems.<\/li><li>if you have&nbsp;psoriasis&nbsp;or other skin problems as they may worsen during treatment with Besremi.<\/li><\/ul>\n\n\n\n<p>Once you have started treatment with Besremi, talk to your doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you develop symptoms of depression (eg if you feel sad, depressed or have suicidal thoughts).<\/li><li>if you develop signs of a severe&nbsp;allergic reaction&nbsp;(eg difficulty breathing, wheezing or&nbsp;hives&nbsp;) while using Besremi &#8211; if so, seek immediate medical attention.<\/li><li>if you develop symptoms of a cold or respiratory infection (eg difficulty breathing, cough, fever and chest pain).<\/li><li>if you experience vision changes &#8211; you need to talk to a doctor and have an eye examination immediately.&nbsp;Severe eye problems may occur during treatment with Besremi.&nbsp;Your doctor will usually check your vision before starting treatment.&nbsp;If you have health problems that can lead to eye problems, e.g.&nbsp;diabetes&nbsp;or high&nbsp;blood pressure&nbsp;, your doctor should also check your vision during treatment.&nbsp;If your vision deteriorates, your doctor may decide to discontinue your treatment.<\/li><\/ul>\n\n\n\n<p>Dental or gum diseases that can lead to&nbsp;tooth loss&nbsp;can occur with drugs containing&nbsp;interferon.&nbsp;In addition,&nbsp;dry mouth&nbsp;can&nbsp;damage the teeth and oral mucosa during long-term treatment with Besremi.&nbsp;You should brush your teeth thoroughly twice a day and undergo regular dental checkups.<br><\/p>\n\n\n\n<p>It will take a while before your individual optimal&nbsp;dose of&nbsp;Besremi is reached.&nbsp;Your doctor will decide if it is necessary to treat you with another medicine for an early reduction in your blood levels to prevent blood clots and bleeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children and adolescents as no information is available on the use of Besremi in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Besremi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Do not use Besremi if you are taking telbivudine (to treat&nbsp;hepatitis&nbsp;B) as the combination of these medicines increases the risk of&nbsp;peripheral&nbsp;neuropathy(numbness, stinging or burning sensation in the arms and legs).&nbsp;Tell your doctor if you are being treated with telbivudine.<br><\/p>\n\n\n\n<p>Talk to your doctor especially if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>theophylline (a medicine used to treat lung diseases such as&nbsp;asthma&nbsp;)<\/li><li>methadone&nbsp;(a medicine used to treat pain or opioid dependence)<\/li><li>vortioxetine or&nbsp;risperidone&nbsp;(medicines used to treat mental disorders)<\/li><li>cancer drugs such as those that stop or slow down the growth of blood-forming cells in the&nbsp;bone marrow&nbsp;(eg hydroxycarbamide)<\/li><li>drugs that act on the&nbsp;central nervous system&nbsp;to relieve pain, help you fall asleep, or that have a calming effect (eg morphine, midazolam).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>The effect of Besremi during pregnancy is unknown.&nbsp;The use of Besremi is not recommended during pregnancy.&nbsp;If you are a&nbsp;pregnant&nbsp;woman, your doctor will discuss whether effective contraception should be used during your treatment with Besremi.<br><\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>It is unknown whether Besremi is excreted in human milk.&nbsp;Your doctor will help you decide if you need to stop breast-feeding while you are taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Do not drive or use machines if you feel dizzy, sleepy, or confused while using Besremi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Besremi contains besyl alcohol<\/h2>\n\n\n\n<p>This medicine contains 5 mg of benzyl alcohol in every 0.5 ml.&nbsp;Benzyl alcohol can cause allergic reactions.<\/p>\n\n\n\n<p>Talk to a doctor or pharmacist:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are pregnant or breastfeeding.<\/li><li>if you have liver or kidney disease.<\/li><\/ul>\n\n\n\n<p>Large amounts of benzyl alcohol can be stored in the body and cause&nbsp;side effects(metabolic&nbsp;acidosis&nbsp;).<br><\/p>\n\n\n\n<p><strong>Besremi contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per ml, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Besremi<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Dosage&nbsp;one is determined individually for you by your doctor for your condition.&nbsp;The usual starting dose of Besremi is 100 micrograms every two weeks.&nbsp;Your doctor will then&nbsp;gradually&nbsp;increase your&nbsp;dose&nbsp;and may adjust your&nbsp;dose&nbsp;during treatment.<\/p>\n\n\n\n<p>Your doctor will reduce your starting dose to 50 micrograms if you have severe kidney problems.<br><\/p>\n\n\n\n<p>This medicine is for&nbsp;subcutaneous&nbsp;use which means it is injected into the&nbsp;tissue beneath your skin.&nbsp;It should not be injected into an area of \u200b\u200bthe body where the skin is irritated, red, bruised, infected, or scarred.<\/p>\n\n\n\n<p>If you inject the medicine yourself, you will receive clear instructions on how to prepare and inject the medicine.<\/p>\n\n\n\n<p>To prevent transmission of infectious diseases, never share the pre-filled pen with Besremi with anyone else, even if the needle is changed.<br><\/p>\n\n\n\n<p><strong>Detailed information on how to prepare and inject Besremi can be found in the instructions for use.&nbsp;Read it before using Besremi.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Besremi than you should &nbsp;<\/h2>\n\n\n\n<p>Talk to a doctor as soon as possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Besremi<\/h2>\n\n\n\n<p>You should inject&nbsp;dose&nbsp;one as soon as you remember.&nbsp;If it has been longer than two days since the missed&nbsp;dose, you should skip that&nbsp;dose&nbsp;and inject the next&nbsp;dose&nbsp;when it is time.&nbsp;Do not inject a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Besremi<\/h2>\n\n\n\n<p>Do not stop using Besremi until you have talked to a doctor.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you experience any of the following serious&nbsp;side effects&nbsp;during your treatment with Besremi:<\/strong><br><\/p>\n\n\n\n<p><em>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>change of heartbeat (when the heart beats very fast and unevenly).<\/li><\/ul>\n\n\n\n<p><em>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>suicide attempts, suicidal thoughts<\/li><li>vision loss that can be caused by bleeding in the retina (the retina is the photosensitive layer in the eye) or the accumulation of fat in or under the retina.<\/li><\/ul>\n\n\n\n<p><em>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vision loss that can be caused by damage to the retina (such as blockage of blood vessels in the eye) or&nbsp;optic nerve.<\/li><\/ul>\n\n\n\n<p><em>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blindness<\/li><li>respiratory problems such as shortness of breath, cough, and chest pain that can be caused by pulmonary infiltrate,&nbsp;pneumonia&nbsp;(&nbsp;pneumonia&nbsp;),&nbsp;pulmonary&nbsp;arterial hypertension&nbsp;(high&nbsp;blood pressure&nbsp;in the blood vessels that carry blood from the heart to the lungs), and&nbsp;lung fibrosis&nbsp;(a lung disease when scars form in the lung tissue).<\/li><\/ul>\n\n\n\n<p><em>Adverse reactions&nbsp;that have been reported (affects an unknown number of users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>retinal detachment (you may experience eye problems, including vision changes).<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<p><em>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased number of&nbsp;white blood cell&nbsp;types&nbsp;(called&nbsp;leukocytes&nbsp;) and blood clotting cells (&nbsp;platelets&nbsp;) &#8211;<\/li><li>joint or muscle pain &#8211;<\/li><li>flu-like symptoms, feeling tired &#8211;<\/li><li>in blood samples: increased level of an&nbsp;enzyme&nbsp;called gamma-glutamyltransferase.<\/li><\/ul>\n\n\n\n<p><em>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>respiratory tract infections, runny or stuffy nose, fungal infections<\/li><li>decreased number or size of&nbsp;red blood cells<\/li><li>increase or decrease in thyroid activity increased level of thyroid-stimulating hormone,&nbsp;inflammation&nbsp;of the thyroid gland<\/li><li>increased levels of&nbsp;triglycerides&nbsp;(a type of fat) in the blood, decreased appetite<\/li><li>aggressive behavior, depression, anxiety, difficulty falling asleep or sleeping, mood swings, lack of energy or motivation<\/li><li>headache, dizziness, the impaired feeling of touch or sensation, drowsiness, tingling or stinging sensation<\/li><li>dry eye<\/li><li>damage to the&nbsp;capillaries&nbsp;(very small blood vessels) in the body<\/li><li>breathing problems<\/li><li>diarrhea, nausea, abdominal pain, stomach upset, constipation,&nbsp;dry mouth<\/li><li>liver disease, increased levels of certain liver enzymes (shown in blood tests)<\/li><li>itching, hair loss, rash, redness of the skin,&nbsp;psoriasis, dry and scaly skin,&nbsp;acne, thickening of the outer layer of the skin, increased sweating<\/li><li>a disease called&nbsp;Sj\u00f6gren&#8217;s syndrome&nbsp;when the body&#8217;s immune system attacks&nbsp;glands&nbsp;that form fluid (such as lacrimal and salivary glands),&nbsp;arthritis, pain in the arms and legs, leg pain, painful sudden muscle contraction<\/li><li>fever, weakness, chills, general health problems, irritation or&nbsp;redness&nbsp;at the injection site<\/li><li>in blood tests:&nbsp;antibodies&nbsp;are formed by the body&#8217;s immune system, increased levels of an&nbsp;enzyme&nbsp;called&nbsp;lactate dehydrogenase&nbsp;.<\/li><\/ul>\n\n\n\n<p><em>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection&nbsp;and re-infection with&nbsp;herpes, bacterial infections<\/li><li>increased&nbsp;platelet count<\/li><li>autoimmune&nbsp;disease of the thyroid gland,&nbsp;sarcoidosis&nbsp;(areas of inflamed&nbsp;tissue&nbsp;in different parts of the body)<\/li><li>diabetes<\/li><li>panic attack, hallucination (seeing, hearing, or feeling things that do not exist), feeling stressed, feeling nervous, lack of interest in activities, nightmares, irritability, confusion<\/li><li>damage to the nervous system,&nbsp;migraine, mental disorders (health conditions involving changes in thought, feeling, or behavior), visual or emotional disorders, tremors in the hands<\/li><li>eye discomfort, eyelid eczema<\/li><li>hearing loss, ringing in the ears (&nbsp;tinnitus&nbsp;), dizzy feeling (dizziness)<\/li><li>heart diseases such as heart block (a disease that affects the electrical activity of the heart), blood clots in the blood vessels of the heart, leakage in the aortic valve<\/li><li>high&nbsp;blood pressure, decreased blood supply in certain parts of the body, hematoma (accumulation of blood under the skin), hot flashes<\/li><li>inflammation&nbsp;of lung tissue, cough, nosebleeds, sore throat<\/li><li>inflammation&nbsp;of the stomach, disturbance in the abdominal wall, gas in the intestine, indigestion, painful swallowing, bleeding gums<\/li><li>inflammation&nbsp;of the liver, damage to the liver, enlarged liver<\/li><li>sensitive to sunlight, scaly skin, nail disease<\/li><li>muscle weakness, neck pain, groin pain<\/li><li>inflammation&nbsp;of the bladder, painful urination, increased need to urinate, inability to urinate<\/li><li>sexual problems<\/li><li>pain or&nbsp;itching&nbsp;at the injection site, sensitivity to weather changes<\/li><li>weight loss<\/li><li>in blood tests: increased levels of&nbsp;uric acid,&nbsp;antibodies&nbsp;formed by the body&#8217;s immune system against&nbsp;red blood cells.<\/li><\/ul>\n\n\n\n<p><em>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>bipolar disorder (mood disorders with periods of depression and agitation), mania (extreme agitation or unfounded enthusiasm)<\/li><li>cardiomyopathy&nbsp;(diseases affecting the heart muscle),&nbsp;angina pectoris&nbsp;(a severe chest pain as a result of a blockage of the heart&nbsp;vessels&nbsp;)<\/li><li>liver failure.<\/li><\/ul>\n\n\n\n<p><em>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>idiopathic&nbsp;or thrombotic thrombocytopenic purpura (increased incidence of bruising, bleeding, decreased&nbsp;platelet&nbsp;level,&nbsp;anemia,&nbsp;and extreme weakness)<\/li><li>myocardial ischemia (decreased blood flow to the heart muscle).<br><\/li><\/ul>\n\n\n\n<p><em>Adverse reactions&nbsp;that have been reported (affects an unknown number of users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vogt-Koyanagi-Harada disease (a rare disease that can lead to vision loss, hearing loss, and skin pigmentation), severe&nbsp;allergic reaction<\/li><li>discoloration of the skin<\/li><li>periodontal (affects the gums) and dental diseases, discoloration of the tongue.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Besremi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and the carton after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2-8 \u00b0 C).<\/p>\n\n\n\n<p>Do not freeze.<\/p>\n\n\n\n<p>Keep the pre-filled pen in the outer carton.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>After opening, the pre-filled pen can be stored for a maximum of 30 days in a refrigerator (2\u20138 \u00b0 C) when stored with the cap affixed to the pen and the outer carton to protect from light.<br><\/p>\n\n\n\n<p>Do not use this medicine if you find that the pre-filled pen appears to be damaged, the solution in it is cloudy, contains particles or flakes or has a color other than colorless to light yellow.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ropeginterferon alfa-2b.&nbsp;Each pre-filled&nbsp;pen&nbsp;of 0.5 ml solution contains 250 micrograms of ropeginterferon alfa-2b measured as&nbsp;protein alone&nbsp;corresponding to 500 micrograms \/ ml.<\/li><li>The other ingredients are sodium chloride, polysorbate 80, benzyl alcohol, anhydrous sodium acetate, concentrated acetic acid, and water for injections.&nbsp;For benzyl alcohol and&nbsp;sodium&nbsp;, see section 2 &#8220;Besremi contains benzyl alcohol&#8221; and &#8220;Besremi contains sodium&#8221;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Besremi is supplied as a&nbsp;solution for injection&nbsp;(&nbsp;injection&nbsp;) in a pre-filled&nbsp;pen.&nbsp;Each pre-filled&nbsp;pen&nbsp;contains 0.5 ml of solution.&nbsp;The medicine is available in packs containing 1 pre-filled&nbsp;pen&nbsp;and 2 syringes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>AOP Orphan Pharmaceuticals AG<\/p>\n\n\n\n<p>Wilhelminenstrasse 91 \/ II f<\/p>\n\n\n\n<p>1160 Vienna<\/p>\n\n\n\n<p>Austria<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Besremi contains the active substance peginterferon alfa-2b which belongs to a class of medicines called interferons. Interferon is made by your immune system to inhibit the growth of cancer cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2202,2200],"tags":[9037,9039,9032,9034,9041,9036,9040,9038,9033,9035],"class_list":["post-6006","post","type-post","status-publish","format-standard","hentry","category-b","category-medicines","tag-besremi","tag-besremi-side-effects","tag-ropeginterferon-alpha-2b","tag-ropeginterferon-alpha-2b-side-effects","tag-side-effects-of-besremi","tag-side-effects-of-ropeginterferon-alpha-2b","tag-what-besremi-is-used-for","tag-what-is-besremi","tag-what-is-ropeginterferon-alpha-2b","tag-what-ropeginterferon-alpha-2b-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=6006"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6006\/revisions"}],"predecessor-version":[{"id":12084,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/6006\/revisions\/12084"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=6006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=6006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=6006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}