{"id":5974,"date":"2020-12-29T15:23:33","date_gmt":"2020-12-29T15:23:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5974"},"modified":"2022-11-29T15:08:33","modified_gmt":"2022-11-29T15:08:33","slug":"beriglobin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/beriglobin\/","title":{"rendered":"Beriglobin &#8211; Human Normal Immunoglobulin Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Beriglobin 160 mg\/ml&nbsp;Solution For Injection, Human Normal Immunoglobulin Pre-Filled&nbsp;Syringe<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Is Beriglobin And What Is Beriglobin Injection Used For<\/h2>\n\n\n\n<p>Beriglobin is an immunoglobulin preparation (immunoglobulin G).&nbsp;It contains&nbsp;antibodies&nbsp;against bacteria and&nbsp;viruses.&nbsp;Antibodies&nbsp;are part of the body&#8217;s defenses against&nbsp;infections.<\/p>\n\n\n\n<p>You can get<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>As travel prophylaxis against an infectious liver disease (<a href=\"https:\/\/zeepedia.com\/diseases\/hepatitis-a-infectious-jaundice\/\">Hepatitis\u00a0A<\/a>) when there are less than 2 weeks left until you can be exposed to infection.<\/li><li>As a preventive treatment for\u00a0Hepatitis\u00a0A, if you have been exposed to infection during the last 2 weeks.<\/li><\/ul>\n\n\n\n<p>Your doctor or nurse will give you Beriglobin as an&nbsp;injection&nbsp;into a muscle.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"508\" height=\"281\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2020\/12\/Beriglobin.jpg\" alt=\"Beriglobin\" class=\"wp-image-36446\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2020\/12\/Beriglobin.jpg 508w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2020\/12\/Beriglobin-300x166.jpg 300w\" sizes=\"auto, (max-width: 508px) 100vw, 508px\" \/><figcaption>Beriglobin<\/figcaption><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Take Beriglobin<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Do Not Use Beriglobin<\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to human normal immunoglobulin or any of the other ingredients of this medicine (listed in section 6). <em>Beriglobin uses<\/em> are not for you. <\/li><\/ul>\n\n\n\n<p>Beriglobin must not be given into a blood vessel.&nbsp;Beriglobin must also not be given in a muscle if you have a sharp decrease in the number of&nbsp;platelets&nbsp;(&nbsp;platelets&nbsp;) in the blood or if you have any other bleeding disorder.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking medicine:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are deficient in&nbsp;IgA&nbsp;&#8211;&nbsp;antibody&nbsp;s.&nbsp;In rare cases, you may have an&nbsp;allergic reaction.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are receiving human normal immunoglobulin for the first time.&nbsp;Certain Beriglobin injection side effects&nbsp;may occur more frequently in those receiving human normal immunoglobulin for the first time.<\/li><li>If you have previously received other products for the treatment of the same symptoms.<\/li><li>If Beriglobin has been accidentally given into a blood vessel, you may develop a severe&nbsp;allergic reaction&nbsp;(anaphylactic&nbsp;shock&nbsp;).&nbsp;In other rare cases, it may cause a drop in blood pressure with an&nbsp;anaphylactic reaction, even in people who have previously tolerated treatment with human normal immunoglobulin.<\/li><\/ul>\n\n\n\n<p>If an allergic or&nbsp;anaphylactic reaction&nbsp;is&nbsp;suspected,&nbsp;the injection&nbsp;should&nbsp;be stopped immediately.&nbsp;Early symptoms of an&nbsp;allergic reaction&nbsp;may include <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>Increased&nbsp;heart rate<\/li><li>Palpitations<\/li><li>Vomiting<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Cold<\/a> sweats<\/li><li>Feeling hot<\/li><li>Hives<\/li><li>Itching<\/li><li>Shortness of breath<\/li><\/ul>\n\n\n\n<p>If you experience any of these symptoms, notify the person giving you the&nbsp;injection&nbsp;immediately.<\/p>\n\n\n\n<p>After receiving Beriglobin, the results of certain blood tests (serological tests) may be affected for some time.&nbsp;Tell your doctor that you are taking it if you are going to have blood tests.<\/p>\n\n\n\n<p><strong>Measures to prevent the transmission of infectious agents<\/strong><\/p>\n\n\n\n<p>Beriglobin is produced from blood plasma (the liquid part of the blood).&nbsp;When medicines are made from human blood or&nbsp;plasma,&nbsp;special measures are taken to prevent the&nbsp;transmission of&nbsp;infection&nbsp;to patients.&nbsp;These include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Careful selection of blood and plasma donors to ensure that people at risk of being infected are excluded;<\/li><li>Tests on each donation and on plasma pools for signs of viruses\/infections,<\/li><li>The inclusion of steps in the manufacturing process of blood and plasma products that inactivate\/secrete&nbsp;viruses.<\/li><\/ul>\n\n\n\n<p>Despite these measures, the risk of transmission of&nbsp;infection&nbsp;can not be completely ruled out when using drugs prepared from human blood or&nbsp;plasma.&nbsp;This also applies to infectious agents or infectious diseases of hitherto unknown origin.<\/p>\n\n\n\n<p>The measures taken are considered effective against enveloped&nbsp;viruses&nbsp;such as human immunodeficiency virus (&nbsp;HIV&nbsp;),&nbsp;hepatitis&nbsp;B&nbsp;virus,&nbsp;and&nbsp;hepatitis&nbsp;C&nbsp;virus,&nbsp;and against the non-enveloped&nbsp;virus&nbsp;and&nbsp;hepatitis&nbsp;A. The measures may be of limited value against non-enveloped&nbsp;viruses&nbsp;such as parvovirus B19.<\/p>\n\n\n\n<p>Immunoglobulins have not been associated with the infectious diseases&nbsp;hepatitis&nbsp;A or parvovirus B19, possibly because the&nbsp;antibodies&nbsp;contained in the medicine protect against these&nbsp;infections.<\/p>\n\n\n\n<p>When you are given Beriglobin, it is strongly recommended that the product name and batch number be registered to enable the tracking of the used product.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Beriglobin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription or other vaccines.<\/p>\n\n\n\n<p>Beriglobin may reduce the effect of vaccination with live attenuated viral vaccines such as&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Measles<\/li><li>Rubella<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/mumps\/\">Mumps<\/a><\/li><li>Chickenpox<\/li><\/ul>\n\n\n\n<p>After treatment with Beriglobin, 3 months should elapse before you are vaccinated with live attenuated virus vaccines.&nbsp;In the case of the measles vaccine, you may have to wait up to 1 year after treatment with this tablet.&nbsp;It is therefore important that the doctor performing the vaccination knows that you are being treated or have been treated with Beriglobin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>The safety of Beriglobin during pregnancy and lactation has not been established in studies.&nbsp;Experience to date with immunoglobulin therapy does not indicate harmful effects during pregnancy or in the newborn.&nbsp;Immunoglobulins are excreted in breast milk and may help protect the newborn from certain&nbsp;infections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>The ability to drive or use machines may be impaired by certain&nbsp;side effects associated with Beriglobin.&nbsp;If you experience any&nbsp;side effects&nbsp;during treatment, wait until they pass before driving or using machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Beriglobin Contains Sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, ie&nbsp;essentially &#8216;&nbsp;sodium-free.&nbsp;is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Get Beriglobin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Beriglobin is given as an&nbsp;injection&nbsp;into a muscle.&nbsp;Beriglobin is injected by a doctor or nurse.<\/li><li>Your doctor will determine the&nbsp;dose&nbsp;in relation to your weight.<\/li><li>Usually, you have to lie down when you get an&nbsp;injection.&nbsp;If you get a larger volume, you will be&nbsp;injected&nbsp;in several places to divide the&nbsp;dose.<\/li><li>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Beriglobin Side Effects<\/h2>\n\n\n\n<p>Like all medicines, Beriglobin can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>Your doctor or nurse will monitor you when you receive an&nbsp;injection&nbsp;to see if you may experience any&nbsp;Beriglobin side effects.<\/p>\n\n\n\n<p><strong>Tell your doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty breathing<\/li><li>Pressure over the chest<\/li><li>Swelling of the face and skin<\/li><li>Feeling hot or&nbsp;hives&nbsp;(urticaria)<\/li><li>Drop in blood pressure<\/li><\/ul>\n\n\n\n<p>This can be a sign of a serious&nbsp;allergic reaction&nbsp;and can occur even if you have not had an&nbsp;allergic reaction during previous treatment.&nbsp;(This&nbsp;side effect&nbsp;occurs in an unknown number of users.)<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Very&nbsp;<\/strong><strong>common<\/strong>&nbsp;(may affect more than 1 in 10 people).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Injection site pain<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a><\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fainting<\/li><li>Dizziness<\/li><li>Cramps in the trachea<\/li><li>Rash<\/li><li>Reactions in blood vessels, especially if the drug was accidentally injected into a blood vessel<\/li><li>Nausea<\/li><li>Vomiting<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a> (&nbsp;arthralgia&nbsp;)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/back-hurts\/\">Back pain<\/a><\/li><li>Swelling<\/li><li>Redness<\/li><li>Calluses<\/li><li>Heat<\/li><li>Itching<\/li><li>Bruising<\/li><li>Rash<\/li><li>Hives&nbsp;at the injection site<\/li><li>Overindulge<\/li><li>Feeling sick<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;Postal address<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Beriglobin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton or prefilled syringe after EXP.&nbsp;date.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/li><li>Do not freeze.<\/li><li>Once the package has been opened, its contents must be used immediately.<\/li><li>Beriglobin must not be mixed with other medicines.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is human normal immunoglobulin 160 mg\/ml, of which immunoglobulin G constitutes at least 95%.<\/li><li>The other ingredients are&nbsp;glycine, sodium chloride, sodium hydroxide or&nbsp;hydrochloric acid&nbsp;(for&nbsp;pH&nbsp;adjustment&nbsp;), and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p><strong>Appearance:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Beriglobin is a clear solution.<\/li><li>The color can vary from<ul><li>Colorless<\/li><li>Pale yellow to pale brown during the shelf life<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Pack sizes<\/strong><\/p>\n\n\n\n<p>Beriglobin is available in a pre-filled&nbsp;syringe&nbsp;of 2 ml.<\/p>\n\n\n\n<p>Beriglobin is supplied in the following packages:<\/p>\n\n\n\n<p>1 pre-filled&nbsp;syringe&nbsp;(graduated with headline = 0.1 ml) with 2 ml solution and an injection needle<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><a href=\"https:\/\/www.cslbehring.com\/\" rel=\"noopener\">CSL Behring GmbH<\/a><\/p>\n\n\n\n<p>Emil-von-Behring-Strasse 76<\/p>\n\n\n\n<p>D-35041 Marburg<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Local representative<\/strong>&nbsp;:<\/p>\n\n\n\n<p>CSL Behring AB<\/p>\n\n\n\n<p>Box 712<\/p>\n\n\n\n<p>182 17 Danderyd<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Beriglobin is a human immunoglobulin which has at least 100 IU\/ml of antibodies against hepatitis A. The symptom applied for is the same as the now approved product in ampoules, prophylaxis against hepatitis A.<\/p>\n","protected":false},"author":2,"featured_media":36446,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2202,2200],"tags":[9073,9075,2828,9071,9077,9072,9076,9070,9074,9069],"class_list":["post-5974","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-b","category-medicines","tag-beriglobin","tag-beriglobin-injection","tag-human-normal-immunoglobulin","tag-human-normal-immunoglobulin-injection","tag-side-effects-of-beriglobin","tag-side-effects-of-human-normal-immunoglobulin","tag-what-beriglobin-is-used-for","tag-what-human-normal-immunoglobulin-is-used-for","tag-what-is-beriglobin","tag-what-is-human-normal-immunoglobulin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5974"}],"version-history":[{"count":65,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5974\/revisions"}],"predecessor-version":[{"id":36907,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5974\/revisions\/36907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/36446"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}