{"id":5896,"date":"2020-12-28T14:43:43","date_gmt":"2020-12-28T14:43:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5896"},"modified":"2022-11-23T19:38:28","modified_gmt":"2022-11-23T19:38:28","slug":"bascellex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bascellex\/","title":{"rendered":"Bascellex &#8211; Imikvimod uses, Dose, And Side Effects"},"content":{"rendered":"\n<p> <strong>Bascellex 50 mg\/g Imikvimod Cream<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Bascellex Is And What Is Bascellex Cream Used For<\/h2>\n\n\n\n<p>Your doctor may&nbsp;prescribe&nbsp;Bascellex for the treatment of<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/diseases\/actinic-keratoses\/\">Actinic keratosis<\/a><\/li><\/ul>\n\n\n\n<p>Actinic keratosis&nbsp;is rough skin areas found in people who have been exposed to too much sunlight during their lifetime.&nbsp;Some are skin-colored, and others are greyish, pink, red, or brown.&nbsp;They can be thin and scaly or raised, rough, hard, and wart-like.<\/p>\n\n\n\n<p>The cream is only used for thin&nbsp;actinic keratosis&nbsp;of the face and scalp in patients with normal immune systems when your doctor has decided that cream is the most appropriate treatment.<\/p>\n\n\n\n<p>Bascellex helps your body&#8217;s own immune system to produce natural substances that help fight your actinic&nbsp;keratosis.<\/p>\n\n\n\n<p>Imiquimod contained in Bascellex may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"342\" height=\"216\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/11\/Bascellex.png\" alt=\"\" class=\"wp-image-35338\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Bascellex.png 342w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Bascellex-300x189.png 300w\" sizes=\"auto, (max-width: 342px) 100vw, 342px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Bascellex<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to imikvimod or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using this cream<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have previously used Bascellex or other similar preparations<\/li><li>If you have problems with your immune system<\/li><li>If you have an abnormal&nbsp;blood cell&nbsp;s<\/li><li>Do not use Bascellex until the area to be treated has healed after previous treatment with medication or&nbsp;surgery<\/li><li>Avoid getting&nbsp;cream&nbsp;in the eyes, on the lips, or in the nostrils.&nbsp;If this happens by mistake,&nbsp;the cream is&nbsp;removed by rinsing it with water<\/li><li>Do not use&nbsp;cream&nbsp;internally<\/li><li>Do not use more&nbsp;cream&nbsp;than your doctor has prescribed<\/li><li>Do not cover the treated area where you lubricated Bascellex with a bandage or similar<\/li><li>If you experience too much discomfort in the treated area, wash off&nbsp;the cream&nbsp;with mild soap and water.&nbsp;Once the problems are gone, you can start using&nbsp;the cream&nbsp;again<\/li><li>Do not use sunlight or tanning beds and avoid sunlight as much as possible during treatment with cream.&nbsp;Wear protective clothing and a wide-brimmed headdress when you are outdoors.<\/li><li>Due to the mechanism of action of Bascellex, there is a possibility that the&nbsp;cream&nbsp;may aggravate existing&nbsp;inflammation&nbsp;in the treatment area.<\/li><li>While using Bascellex and until your skin change has healed, the skin in the treatment area will probably look noticeably altered compared to normal skin.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Use in children and adolescents is not recommended <em>Bascellex 50 mg\/g cream<\/em>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Bascellex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;No medicines are known to be incompatible with Bascellex.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.&nbsp;Your doctor will discuss both the risks and benefits of using this cream during pregnancy.<\/p>\n\n\n\n<p>It is not known whether imikvimod is excreted in human milk.&nbsp;Therefore, do not breastfeed your baby during treatment with <strong>Bascellex 50 mg\/g cream<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>This medicine has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bascellex Cream Contains Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, Cetyl Alcohol, Stearyl Alcohol, And Benzyl Alcohol<\/h2>\n\n\n\n<p>Methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) may cause allergic reactions (possibly delayed).&nbsp;Cetyl alcohol and stearyl alcohol can cause local skin reactions (eg <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/contact-dermatitis\/\">contact dermatitis<\/a>).&nbsp;Benzyl alcohol can cause mild local irritation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Children and young people<\/em><\/h3>\n\n\n\n<p>Use in children and adolescents is not recommended.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Adults<\/em><\/h3>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.&nbsp;Wash your hands thoroughly before and after applying the&nbsp;cream.&nbsp;Do not cover the treated area with bandages or&nbsp;compresses&nbsp;after the cream has been applied.&nbsp;Open a new&nbsp;sachet&nbsp;each time you use&nbsp;a cream&nbsp;one.&nbsp;Discard any&nbsp;cream&nbsp;left over after use.&nbsp;Do not save the opened bag for later use.<br><\/p>\n\n\n\n<p><strong>Bascellex&nbsp;cream&nbsp;Application instructions<\/strong><br><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20170228000022#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/2d4b7ca8-147c-4b12-a0fc-0f88d6cd0324\" alt=\"Application instructions\"\/><\/a><\/figure><\/div>\n\n\n<p>Application instructions<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Before going to bed, wash your hands and the treatment area with mild soap and water.&nbsp;Dry carefully.<\/li><li>Open a new&nbsp;sachet&nbsp;and squeeze the&nbsp;cream&nbsp;on your fingertip.<\/li><li>Apply&nbsp;cream&nbsp;to the affected area.&nbsp;Gently&nbsp;massage cream&nbsp;one into the area until it has penetrated the skin.<\/li><li>Once the&nbsp;cream&nbsp;has been applied, discard the opened bag.&nbsp;Wash your hands with soap and water.<\/li><li>Leave Bascellex on the skin for about 8 hours.&nbsp;Do not shower or bathe during this time.<\/li><\/ol>\n\n\n\n<p>After about 8 hours, wash the area where Bascellex was lubricated with mild soap and water.<\/p>\n\n\n\n<p>Apply cream three times a week on Monday, Wednesday, and Friday.&nbsp;A&nbsp;sachet contains enough&nbsp;cream&nbsp;to cover an area of \u200b\u200b25 cm&nbsp;<sup>2<\/sup>.&nbsp;Continue treatment for 4 weeks.&nbsp;Four weeks after completing the first treatment, your doctor will assess your skin.&nbsp;If not all skin changes have disappeared, you may need to treat for another 4 weeks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Bascellex<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;sachet, apply a&nbsp;cream&nbsp;as soon as you remember and then continue with the regular schedule.&nbsp;Do not use&nbsp;the cream&nbsp;more than once a day.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Bascellex Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe skin reactions have been reported but are rare. Stop using cream and tell your doctor immediately&nbsp;if you get sores on the skin or spots on the skin that start as small red areas and develop into small circles, possibly with symptoms such as&nbsp;<ul><li>Itching<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a><\/li><li>General malaise<\/li><li>Sore joints<\/li><li><a href=\"https:\/\/zeepedia.com\/diseases\/distinction-and-double-vision-in-adults\/\">Vision problems<\/a><\/li><li>Burning<\/li><li>Sore or itchy eyes<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Cold<\/a> sores<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor or pharmacist as soon as possible<\/strong> if <em>Bascellex side effects<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you do not feel well when using Bascellex<\/li><li>If your skin reacts strongly when using Bascellex, do not apply more&nbsp;cream&nbsp;but wash the area with mild soap and water<\/li><li>If you become more susceptible to&nbsp;infection, bruise more easily, or feel unusually tired.&nbsp;These may be symptoms of a decrease in the number of&nbsp;blood cells observed in some individuals.<br><\/li><\/ul>\n\n\n\n<p>Some patients have experienced a change in skin color in the area where Bascellex was applied.&nbsp;Although these changes usually go back over time, in some patients they can become permanent.&nbsp;A small number of patients have experienced some hair loss at the treatment site or in the surrounding area.<br><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Many of the side effects of Bascellex are due to its local effect on your skin.&nbsp;Local skin reactions may be a sign that the medicine is working as intended.<\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The skin may be slightly itchy.<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain<\/li><li>Burning sensation<\/li><li>Irritation<\/li><li>Redness<\/li><li>Headache<\/li><li>Anorexia<\/li><li>Nausea<\/li><li>Muscle pain<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a><\/li><li>Fatigue<\/li><\/ul>\n\n\n\n<p>If the skin reaction becomes too bothersome during treatment, talk to your doctor.&nbsp;He\/she may advise you to stop applying Bascellex for a few days (ie have a short break from treatment).&nbsp;If there are any other signs of&nbsp;infection, discuss this with your doctor.<\/p>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Changes in the site of the application<ul><li>Bleeding<\/li><li>Inflammation<\/li><li>Secretion of fluid<\/li><li>Sensitivity<\/li><li>Swelling<\/li><li>Small swollen areas of the skin<\/li><li>Tingling<\/li><li>Crusting<\/li><li>Scarring<\/li><li>Sores<\/li><li>Feeling of heat or discomfort<\/li><\/ul><\/li><li>Inflammation&nbsp;of the nasal mucosa<\/li><li>Stuffy nose<\/li><li>Flu&nbsp;or&nbsp;flu-like symptoms<\/li><li>Depression<\/li><li>Eye irritation<\/li><li>Swollen eyelids<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">Sore throat<\/a><\/li><li>Diarrhea<\/li><li>Actinic keratosis<\/li><li>Swollen face<\/li><li>Wound<\/li><li>Pain in arms or legs<\/li><li>Fever<\/li><li>Weakness<\/li><li>Tremors<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Bascellex<\/h2>\n\n\n\n<ol class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and sachets after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Do not store above 25 \u00b0 C.<\/li><li>Dosage bags should not be reused once opened.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration For Bascellex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is imiquimod.&nbsp;Each&nbsp;sachet&nbsp;contains 12.5 mg of imiquimod in 250 mg of&nbsp;cream&nbsp;(1 g of&nbsp;cream&nbsp;contains 50 mg of imiquimod).<\/li><li>Excipients are <ul><li>Isostearic acid<\/li><li>Benzyl alcohol<\/li><\/ul><ul><li>Cetyl alcohol, stearyl alcohol<\/li><li>White soft paraffin<\/li><li>Polysorbate 60<\/li><li>Sorbitan stearate<\/li><li>Glycerol<\/li><li>Methyl parahydroxybenzoate (E218)<\/li><li>Propyl parahydroxybenzoate (E216)<\/li><li>Xanthan gum<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Bascellex is white to pale yellow&nbsp;cream.<\/li><li>The cream&nbsp;is available in pack sizes of 12 or 24 single foil bags of aluminum foil, which contain (250 mg cream\/sachet).<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Sun Pharmaceutical Industries Europe BV Polarisavenue 87 2132 JH Hoofddorp Netherlands<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names<\/strong><br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Belgium<\/td><td>Bascellex<\/td><\/tr><tr><td>Germany<\/td><td>Aksunim<\/td><\/tr><tr><td>France<\/td><td>Bascellex<\/td><\/tr><tr><td>Netherlands<\/td><td>Bascellex<\/td><\/tr><tr><td>Norway<\/td><td>Bascellex<\/td><\/tr><tr><td><\/td><td><\/td><\/tr><tr><td>UK<\/td><td>Bascellex<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Bascellex for the cure of actinic keratosis. There are rough areas of skin initiated in people who have been visible to a lot of sunlight over the course of their lifespan.<\/p>\n","protected":false},"author":2,"featured_media":35338,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2202,2200],"tags":[9292,9294,9287,9289,9291,9296,9295,9290,9288,9293],"class_list":["post-5896","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-b","category-medicines","tag-bascellex","tag-bascellex-cream","tag-imikvimod","tag-imikvimod-cream","tag-imikvimod-side-effects","tag-side-effects-of-bascellex","tag-what-bascellex-is-used-for","tag-what-imikvimod-is-used-for","tag-what-is-imikvimod","tag-wht-is-bascellex"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5896","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5896"}],"version-history":[{"count":66,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5896\/revisions"}],"predecessor-version":[{"id":35340,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5896\/revisions\/35340"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/35338"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5896"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5896"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5896"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}