{"id":5822,"date":"2020-12-26T15:21:05","date_gmt":"2020-12-26T15:21:05","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5822"},"modified":"2021-07-09T06:03:00","modified_gmt":"2021-07-09T06:03:00","slug":"bactrim-bactrim-forte","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/bactrim-bactrim-forte\/","title":{"rendered":"Bactrim \/ Bactrim forte – Trimethoprim and Sulfamethoxazole uses, dose and side effects"},"content":{"rendered":"\n
\n\nBactrim 400 mg \/ 80 mg tablets, Bactrim forte 800 mg \/ 160 mg tablets, trimethoprim and sulfamethoxazole<\/p>\n\n\n\n
1. What Bactrim \/ Bactrim forte is and what is it used for<\/h2>\n\n\n\n
Bactrim \/ Bactrim forte is a combination of two substances (sulfamethoxazole and trimethoprim) that work together. These inhibit the bacterium’s metabolism and thereby have a bactericidal effect. <\/p>\n\n\n\n
Bactrim \/ Bactrim forte tablets are used in adults, adolescents, and children from 6 years of age. <\/p>\n\n\n\n
Bactrim \/ Bactrim forte is mainly used for various types of infection in the urinary tract and in the prostate ( bladder neck gland ) as well as for worsening of chronic respiratory infection. Other infections (such as rubella, typhoid, and paratyphoid fever) can also be treated with Bactrim \/ Bactrim forte.<\/p>\n\n\n\n
Furthermore, Bactrim \/ Bactrim forte is used prophylactically and in the treatment of infections caused by Pneumocystis jirovecii<\/em>, especially in patients with weakened immune systems. Bactrim forte contains twice the number of active ingredients compared to Bactrim. <\/p>\n\n\n\n
2. What you need to know before taking Bactrim \/ Bactrim forte<\/h2>\n\n\n\n
Do not use Bactrim \/ Bactrim forte<\/h2>\n\n\n\n
if you are hypersensitive (allergic) to trimethoprim, sulfamethoxazole, or any of the other ingredients of Bactrim \/ Bactrim forte.<\/li>
if you have severe liver damage or blood disease.<\/li>
Bactrim \/ Bactrim forte should not be used in children younger than 6 weeks.<\/li>
if you have severe renal impairment<\/li>
if you are being treated with dofetilide (used for arrhythmias in the heart).<\/li><\/ul>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
If you have impaired kidney function or folate deficiency, you should consult a doctor before starting treatment with Bactrim \/ Bactrim forte.<\/li>
if you are over 65 years of age, malnourished, or severely dehydrated, you should also consult a doctor before starting treatment with Bactrim \/ Bactrim forte .<\/li>
if you have cystic fibrosis, you should consult your doctor before starting treatment with Bactrim \/ Bactrim forte .<\/li><\/ul>\n\n\n\n
Bactrim can in rare cases affect the white blood cells so that the defense against infection deteriorates. If you get an infection with symptoms such as fever with severe general deterioration or fever with local infection symptoms such as sore throat\/throat\/mouth or urination problems, you should see a doctor as soon as possible so that blood tests can rule out a lack of white blood cells ( agranulocytosis ). It is important that you then information about your medication. <\/p>\n\n\n\n
Skin reactions, which may be life-threatening ( Stevens-Johnson syndrome, a drug-induced rash with increased white blood cell count ( eosinophilia ) and systemic symptoms (DRESS) and toxic epidermal necrolysis (TEN); an immunological reaction which may lead to skin detachment, have been reported when using trimethoprim and sulfamethoxazole, it can start as red-violet target-like or round spots with blistering in the middle, often symmetrically widespread, on the torso. <\/p>\n\n\n\n
Additional signs to be aware of are sores in the mouth, throat, nose, genitals, or eye inflammation (red and swollen eyes). <\/p>\n\n\n\n
The skin reactions, which can be life-threatening, are often followed by flu-like symptoms. The rash can develop into blisters over large areas or skin detachment. <\/p>\n\n\n\n
The risk of serious skin reactions is greatest during the first weeks of treatment. <\/p>\n\n\n\n
If you have had Stevens-Johnson syndrome, DRESS, or TEN after using trimethoprim, sulfamethoxazole in Bactrim, you should never use medicines containing trimethoprim and sulfamethoxazole again. <\/p>\n\n\n\n
If you get a rash or signs of these skin reactions, stop taking Bactrim immediately, and contact your doctor immediately and tell them that you are taking this medicine. <\/p>\n\n\n\n
Stop taking Bactrim and contact a doctor immediately if you get any of the following symptoms ( angioedema ):<\/p>\n\n\n\n
\u2022 swelling of the face, tongue, or throat<\/p>\n\n\n\n
\u2022 difficulty swallowing<\/p>\n\n\n\n
\u2022 hives and difficulty breathing <\/p>\n\n\n\n
Stop taking Bactrim and contact your doctor as soon as possible if you experience unexplained muscle pain, muscle cramps, or muscle weakness.<\/p>\n\n\n\n
Other medicines and Bactrim \/ Bactrim forte<\/h2>\n\n\n\n
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. The effect of Bactrim \/ Bactrim forte may affect or be affected if Bactrim \/ Bactrim forte and certain other medicines are taken at the same time. <\/p>\n\n\n\n
It concerns:<\/p>\n\n\n\n
chloropropamide, glibenclamide, repaglinide, pioglitazone, and glipizide (for age-related diabetes),<\/li>
memantine (for dementia),<\/li>
warfarin (for blood clots),<\/li>
ciclosporin, tacrolimus, and azathioprine (inhibits the immune system),<\/li>