{"id":5816,"date":"2020-12-26T15:15:20","date_gmt":"2020-12-26T15:15:20","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5816"},"modified":"2021-07-09T06:02:37","modified_gmt":"2021-07-09T06:02:37","slug":"acids","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/acids\/","title":{"rendered":"Acids &#8211; Azithromycin dihydrate uses, dose and side effects"},"content":{"rendered":"\n<p> 15 mg \/ g\u00a0eye drops, solution in\u00a0single-dose container<br>azithromycin\u00a0dihydrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Azyter is and what it is used for<\/h2>\n\n\n\n<p>Azytes contain azithromycin, an&nbsp;antibiotic&nbsp;belonging to the macrolide antibiotic class.<br><\/p>\n\n\n\n<p>Azytes are used for the local treatment of certain&nbsp;<strong>eye infections&nbsp;caused by bacteria in adults (including the elderly) and in children from newborns to 17 years<\/strong>&nbsp;.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>persistent bacterial infection of the conjunctiva (&nbsp;conjunctivitis&nbsp;).<\/li><li>trachoma conjunctivitis (special&nbsp;eye infection&nbsp;caused by bacteria called&nbsp;<em>Chlamydia trachomatis<\/em>&nbsp;which occurs in developing countries).<\/li><\/ul>\n\n\n\n<p>Azithromycin dihydrate contained in Azyter may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Azyter<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Azyter<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to azithromycin, to any other&nbsp;antibiotic&nbsp;of the&nbsp;macrolide&nbsp;class&nbsp;or to a&nbsp;medium carbon chain&nbsp;triglyceride&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist or nurse before using Azyter.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If an&nbsp;allergic reaction&nbsp;occurs, stop using the medicine and consult your doctor.<\/li><li>If you do not experience improvement within three days of starting treatment or if you experience abnormal symptoms, consult your doctor.<\/li><li>Due to&nbsp;eye infection, the use of contact lenses is not recommended.<\/li><\/ul>\n\n\n\n<p>This medicine&nbsp;<strong>is for eye use only.<\/strong><\/p>\n\n\n\n<p><strong>Do not inject or swallow<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Azytes<\/h2>\n\n\n\n<p>If you are using any other medicine to be applied to the eye, you should:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>apply for the other ophthalmic medicine first,<\/li><li>wait 15 minutes,<\/li><li>apply Azyter finally.<\/li><\/ol>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>Azytes can be used during pregnancy.<\/p>\n\n\n\n<p>Your doctor may&nbsp;prescribe&nbsp;this medicine for you during pregnancy if your doctor considers it necessary.<br><\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>There is only limited data on the excretion of azithromycin in breast milk.&nbsp;This medicine can be used during breast-feeding<br><\/p>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may experience transient blurred vision after&nbsp;administering the&nbsp;medicine to the eye.&nbsp;Wait until you regain normal vision before driving or using machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Azyter<\/h2>\n\n\n\n<p>This medicine should be administered to the eye (&nbsp;ocular&nbsp;use).<br><\/p>\n\n\n\n<p>Always use this medicine exactly as your doctor or your doctor has told you.&nbsp;If you are not sure, talk to your or your child&#8217;s doctor or pharmacist.<br><\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;for adults (including the elderly) and children from newborns to 17 years is one drop twice daily in the eye \/ eyes to be treated: one drop in the morning and one drop in the evening.<\/p>\n\n\n\n<p>The duration of treatment is three days.<\/p>\n\n\n\n<p><strong>Because the medicine has a long-lasting effect, it is not necessary to continue treatment for more than three days, even though you may still have signs of the bacterial infection.<\/strong><br><\/p>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Azytes should be administered as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>wash your hands thoroughly before and after applying the medicine,<\/li><li>drip a drop into the eye to be treated while looking upwards while pulling the lower eyelid slightly downwards,<\/li><li>avoid touching the eye and eyelids with the dropper tip of the single-dose container,<\/li><li><strong>discard the single-dose container after use.&nbsp;You should not save it for later use<\/strong>.<\/li><\/ul>\n\n\n\n<p>DO NOT INJECT;&nbsp;DO NOT SWALLOW.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Azyter<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Azyter<\/h2>\n\n\n\n<p>Always consult your doctor if you are considering stopping treatment.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Tell your doctor immediately if you get any of the following symptoms after taking this medicine, as the symptoms may be severe.<\/strong><br><\/p>\n\n\n\n<p><em>Uncommon (affects up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe&nbsp;allergic reaction&nbsp;that causes swelling of the face or throat (&nbsp;angioedema&nbsp;).<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe skin reactions: skin rash, sudden and severe skin reactions, blisters on skin, mouth, eyes and genitals (&nbsp;Stevens-Johnson syndrome&nbsp;(SJS) or&nbsp;toxic epidermal necrolysis&nbsp;(TEN)), skin rash together with e.g.&nbsp;fever, swollen&nbsp;glands&nbsp;and an increase in a type of&nbsp;white blood cell&nbsp;(&nbsp;eosinophils&nbsp;), rash such as small, itchy, red lumps (drug reaction associated with an increase in the amount of&nbsp;eosinophilsand symptoms affecting the whole body (DRESS)), generalized&nbsp;redness&nbsp;of the skin with scaling over large parts of the body (exfoliative&nbsp;dermatitis), rash characterized by rapid appearance of areas of red skin full of small purulent blisters (small blisters filled with white \/ yellow fluid) (&nbsp;acute&nbsp;generalized exanthematous&nbsp;pustulosis&nbsp;(AGEP)).<\/li><\/ul>\n\n\n\n<p>If you develop these skin symptoms, stop using azithromycin and contact your doctor or see a hospital immediately.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;were observed when the preparation was administered:<br><\/p>\n\n\n\n<p><em>Very common (affects more than 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>transient discomfort in the eye (&nbsp;itching, burning, tingling).<\/li><\/ul>\n\n\n\n<p><em>Common (affects up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dimsyn,<\/li><li>a sticky feeling in the eye,<\/li><li>the sensation of foreign objects in the eye.<\/li><\/ul>\n\n\n\n<p><em>Uncommon (affects 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reaction&nbsp;(hypersensitivity),<\/li><li>inflammation&nbsp;of the white of the eye (may be due to&nbsp;infection&nbsp;or&nbsp;allergy&nbsp;) (&nbsp;conjunctivitis&nbsp;),<\/li><li>allergic&nbsp;inflammation&nbsp;of the whites of the eyes (allergic&nbsp;conjunctivitis&nbsp;),<\/li><li>inflammation&nbsp;of the cornea (&nbsp;keratitis&nbsp;),<\/li><li>itchy skin on the eyelids (eyelid eczema),<\/li><li>dryness,&nbsp;redness, swelling of the eyelids (eyelid edema),<\/li><li>eye allergy,<\/li><li>tear secretion.<\/li><li>red eyelids (eyelid erythema),<\/li><li>red eyes (&nbsp;conjunctival&nbsp;hyperemia&nbsp;).<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Azyter<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the outer carton and disposable container.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>\u2022 Store single-dose containers&nbsp;<strong>in the&nbsp;<\/strong><strong>outer carton<\/strong>&nbsp;.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p><strong>Dispose of opened&nbsp;single-dose container&nbsp;and any remaining solution immediately after first use.&nbsp;Do not save it for later use.<\/strong><br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is azithromycin dihydrate.&nbsp;One gram of solution contains 15 mg of azithromycin dihydrate corresponding to 14.3 mg of azithromycin.&nbsp;A&nbsp;single-dose container&nbsp;of 250 mg solution contains 3.75 mg azithromycin dihydrate.<\/li><li>The other ingredients are&nbsp;triglycerides&nbsp;, medium carbon chain.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Azytes are a solution for ocular use (&nbsp;eye drops&nbsp;, solution)&nbsp;contained&nbsp;in&nbsp;single-dose containers&nbsp;, each container containing 0.25 g of the preparation.&nbsp;Azytes are a clear, colorless or yellowish, oily liquid.<\/p>\n\n\n\n<p>The package contains six&nbsp;single-dose containers&nbsp;in one bag, which is sufficient for a treatment regimen.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Th\u00e9a Laboratories<\/p>\n\n\n\n<p>12, rue Louis Bl\u00e9riot<\/p>\n\n\n\n<p>63017 Clermont-Ferrand Cedex 2<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Th\u00e9a Laboratories<\/p>\n\n\n\n<p>12, rue Louis Bl\u00e9riot<\/p>\n\n\n\n<p>63017 Clermont-Ferrand Cedex 2<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p>or<br><\/p>\n\n\n\n<p>Laboratory Unither<\/p>\n\n\n\n<p>Zi de la Gu\u00e9rie<\/p>\n\n\n\n<p>50200 Coutances<\/p>\n\n\n\n<p>France<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Azytes contain azithromycin, an antibiotic belonging to the macrolide antibiotic class.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[9430,9432,9425,9428,9434,9429,9433,9427,9431,9426],"class_list":["post-5816","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-acids","tag-acidseye-drops","tag-azithromycin-dihydrate","tag-azithromycin-dihydrate-eye-drops","tag-side-effects-of-acids","tag-side-effects-of-azithromycin-dihydrate","tag-what-acids-is-used-for","tag-what-azithromycin-dihydrate-is-used-for","tag-what-is-acids","tag-what-is-azithromycin-dihydrate"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5816"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5816\/revisions"}],"predecessor-version":[{"id":12210,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5816\/revisions\/12210"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5816"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5816"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}