{"id":5755,"date":"2020-12-25T15:26:56","date_gmt":"2020-12-25T15:26:56","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5755"},"modified":"2021-07-13T07:39:55","modified_gmt":"2021-07-13T07:39:55","slug":"atrovent","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/atrovent\/","title":{"rendered":"Atrovent &#8211; Ipratropium bromide uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n20 micrograms \/ dose&nbsp;inhalation spray&nbsp;, solution of&nbsp;<br>ipratropium bromide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Atrovent is and what it is used for<\/h2>\n\n\n\n<p>Atrovent has a tracheal dilating effect.&nbsp;Atrovent has an effect within 15 minutes after&nbsp;inhalation.&nbsp;The maximum effect is reached after 1-2 hours.&nbsp;The effect lasts for up to 6 hours.<\/p>\n\n\n\n<p>Atrovent is used in&nbsp;asthma&nbsp;and chronic&nbsp;obstructive pulmonary disease&nbsp;(COPD), which is a&nbsp;chronic&nbsp;respiratory disease with difficulty breathing.&nbsp;Ipratropium bromide found in Atrovent may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Atrovent<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Atrovent:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ipratropium bromide or any of the other ingredients of this medicine (listed in section 6).<\/li><li>in case of hypersensitivity to atropine or similar substances, eg hyoscyamine or scopolamine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Atrovent:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have&nbsp;glaucoma&nbsp;with a narrow&nbsp;ventricular angle.<\/li><li>if you have prostate enlargement or bladder narrowing.<\/li><li>if you have&nbsp;cystic fibrosis.&nbsp;In people with&nbsp;cystic fibrosis, the risk of developing bowel function may increase.<\/li><\/ul>\n\n\n\n<p>Stop taking Atrovent and contact a doctor immediately if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you get a severe&nbsp;allergic reaction&nbsp;(see section 4 Possible&nbsp;side effects&nbsp;).<\/li><li>after&nbsp;inhalation&nbsp;of the medicine, you suddenly have a spasm in the airways (see section 4 Possible&nbsp;side effects&nbsp;).<\/li><\/ul>\n\n\n\n<p>Do not&nbsp;inhale&nbsp;more&nbsp;than your doctor prescribes.&nbsp;Always consult a doctor if breathing difficulties persist or worsen despite treatment.&nbsp;In the case of&nbsp;acute&nbsp;deterioration of lung function, a doctor should be consulted immediately.<br><\/p>\n\n\n\n<p>In rare cases, eye problems (pupillary enlargement, the pressure increase in the eye,&nbsp;glaucoma&nbsp;with a narrow&nbsp;ventricular angle, eye pain) have been reported when Atrovent comes into contact with the eyes.&nbsp;It is therefore important to use Atrovent&nbsp;inhalation&nbsp;spray&nbsp;according to the instructions, especially for patients who have&nbsp;glaucoma&nbsp;with a narrow&nbsp;ventricular angle.&nbsp;If Atrovent accidentally gets into the eyes, the eyes should be rinsed with running water.<br><\/p>\n\n\n\n<p>Pain or discomfort from the eyes, visual phenomena, and at the same time red eyes can be signs of&nbsp;acute&nbsp;glaucoma&nbsp;with a narrow&nbsp;ventricular angle.&nbsp;Seek an ophthalmologist immediately in such cases.<br><\/p>\n\n\n\n<p>Atrovent can cause&nbsp;dry mouth, which in long-term treatment can lead to tooth and oral mucosal damage.&nbsp;Teeth should be thoroughly cleaned with fluoride toothpaste twice daily.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Atrovent<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Tracheal dilators of a different type (so-called beta-2 stimulators, ie medicines containing eg&nbsp;salbutamol&nbsp;or&nbsp;terbutaline&nbsp;) and medicines containing theophylline or similar substances may potentiate the effect of Atrovent.&nbsp;In one who is suffering from&nbsp;glaucoma&nbsp;with a narrow&nbsp;chamber angle, the combination of Atrovent and beta-2-agonists increases the risk of&nbsp;acute&nbsp;glaucoma.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Limited experience of use during pregnancy.&nbsp;Therefore, consult a physician if you use Atrovent more than temporarily during pregnancy.<br><\/p>\n\n\n\n<p>It is not known if Atrovent passes into breast milk.&nbsp;Therefore, consult a physician&nbsp;<em>before<\/em>&nbsp;regular use during breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Atrovent can cause dizziness and blurred vision.&nbsp;You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Atrovent<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Atrovent&nbsp;inhalation&nbsp;spray&nbsp;is primarily intended for regular use.<br><\/p>\n\n\n\n<p><em>The recommended&nbsp;dose&nbsp;for adults (including the elderly) and children over 6 years:<\/em><\/p>\n\n\n\n<p>2&nbsp;inhalations&nbsp;are 4 times daily.&nbsp;Max 12 inhalations \/ day.<\/p>\n\n\n\n<p>Contact a doctor if you feel that the maximum&nbsp;dose is&nbsp;not enough.<br><\/p>\n\n\n\n<p><em>Use for children<\/em><\/p>\n\n\n\n<p>Experience in treating children is limited.&nbsp;Treatment of children under the age of 12 should therefore take place under the supervision of healthcare professionals.<br><\/p>\n\n\n\n<p><strong>Instructions for use<\/strong><\/p>\n\n\n\n<p>Before a new Atrovent&nbsp;inhalation&nbsp;spray&nbsp;is used for the first time or not used for 3 days, two&nbsp;doses&nbsp;should&nbsp;be expelled into the air.<br><\/p>\n\n\n\n<p>Do this&nbsp;<em>every<\/em>&nbsp;time Atrovent&nbsp;inhalation&nbsp;is used:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Remove the protective cap from the nozzle.<\/li><li>Exhale deeply (outside the inhaler).<\/li><li>Hold the&nbsp;inhalation spray&nbsp;vertically with the bottom facing up (Fig. 1) and close your lips around the mouthpiece. <a href=\"https:\/\/www.fass.se\/LIF\/product;jsessionid=e8-afCCz5QwySrb3GwVvYX5j6oTwceNuw-qKCIhwWB__JZfx9pox!1001412091?userType=2&amp;nplId=19781215000037#\" rel=\"noopener\"><\/a>Fig. 1<\/li><li>Inhale deeply and at the same time press the bottom of the inhalation spray (this releases a&nbsp;dose&nbsp;).<\/li><li>Hold your breath for a few seconds, then take one&nbsp;inhalation spray&nbsp;from your mouth and exhale.<\/li><li>Replace the protective cap.<\/li><\/ol>\n\n\n\n<p>The container is opaque.&nbsp;It is therefore not possible to see when it is empty.&nbsp;Each pack gives 200&nbsp;doses.&nbsp;When these&nbsp;doses&nbsp;have been consumed, the bottle still appears to contain a small amount of liquid.&nbsp;However, the packaging should be replaced with a new one to be sure of getting the right&nbsp;dose.<br><\/p>\n\n\n\n<p>The nozzle should be cleaned at least once a week by first removing the cap and removing the medicine container and then rinsing the nozzle with warm water until no drug or dirt residue can be seen.&nbsp;Allow to air dry and then insert the medicine container and put on the lid.<br><\/p>\n\n\n\n<p>The nozzle has been designed to deliver the right&nbsp;dose&nbsp;of Atrovent.&nbsp;Other nozzles should not be used for Atrovent, nor should the Atrovent nozzle be used for other medicines.<br><\/p>\n\n\n\n<p>There is overpressure in the aerosol bottle.&nbsp;It must not be exposed to force or temperature above 50 \u00b0 C.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>Stop taking Atrovent and contact a doctor immediately if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you get swelling of the face, tongue, or throat, difficulty swallowing,&nbsp;hives, difficulty breathing, or a sudden feeling of fainting.&nbsp;This may be a sign of an&nbsp;allergic reaction&nbsp;or&nbsp;angioedema.<\/li><li>after&nbsp;inhalation&nbsp;of the medicine, you experience sudden,&nbsp;acute&nbsp;wheezing or shortness of breath (respiratory cramps).<\/li><\/ul>\n\n\n\n<p>This may occur in less common cases in connection with the use of Atrovent.<br><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em>: Dizziness, headache, cough, irritation of the throat, disorders of intestinal function,&nbsp;dry mouth&nbsp;(careful oral hygiene is important), nausea.<br><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>: Hypersensitivity.&nbsp;Ocular disorders such as&nbsp;glaucoma, pressure increases in the eye, visual disturbances, mydriasis, eye pain.&nbsp;Cardiac arrhythmia (&nbsp;supraventricular&nbsp;tachycardia&nbsp;), palpitations, cramping of the larynx, swelling of the throat, dry throat, swelling of the oral mucosa, vomiting, diarrhea, constipation,&nbsp;inflammation&nbsp;of the oral mucosa, rash,&nbsp;itching, difficulty urinating.<br><\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em>: Difficulty adjusting vision at different distances,&nbsp;atrial fibrillation, increased heart rate,&nbsp;hives.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Atrovent<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>The spray container must not be exposed to direct sunlight, heat, or frost.<\/p>\n\n\n\n<p>There is overpressure in the aerosol bottle.&nbsp;It must not be exposed to force or temperature above 50 \u00b0 C.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is ipratropium bromide monohydrate equivalent to 20 micrograms of anhydrous ipratropium bromide per&nbsp;dose.<\/p>\n\n\n\n<p>-The other ingredients are anhydrous&nbsp;ethanol, anhydrous citric acid, purified water, and&nbsp;propellant&nbsp;norflurane (HFA 134a).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Boehringer Ingelheim International GmbH<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><em>Information is provided by<\/em><\/p>\n\n\n\n<p>Boehringer Ingelheim AB<\/p>\n\n\n\n<p>Box 92008<\/p>\n\n\n\n<p>120 06 Stockholm<\/p>\n\n\n\n<p>Tel 08-721 21 00<\/p>\n\n\n\n<p>email: info.sto@boehringer-ingelheim.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Atrovent has a tracheal dilating effect. Atrovent has an effect within 15 minutes after inhalation. The maximum effect is reached after 1-2 hours. The effect lasts for up to 6 hours.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[9679,9682,6729,9677,9683,9678,9681,9676,9680],"class_list":["post-5755","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-atrovent","tag-atrovent-spray","tag-ipratropium-bromide","tag-ipratropium-bromide-spray","tag-side-effects-of-atrovent","tag-side-effects-of-ipratropium-bromide","tag-what-atrovent-is-used-for","tag-what-ipratropium-bromide-is-used-for","tag-what-is-atrovent"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5755","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5755"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5755\/revisions"}],"predecessor-version":[{"id":12328,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5755\/revisions\/12328"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5755"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5755"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5755"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}