{"id":5717,"date":"2020-12-24T15:06:02","date_gmt":"2020-12-24T15:06:02","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5717"},"modified":"2021-07-13T07:40:52","modified_gmt":"2021-07-13T07:40:52","slug":"atracurium-kalceks","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/atracurium-kalceks\/","title":{"rendered":"Atracurium Kalceks &#8211; Atracurium besilate uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n10 mg \/ ml&nbsp;injection \/&nbsp;infusion&nbsp;solution&nbsp;<br>Atracurium besilate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Atracurium Kalceks is and what it is used for<\/h2>\n\n\n\n<p>Atracurium Kalceks belongs to a group of medicines called muscle relaxants.<\/p>\n\n\n\n<p>Atracurium Kalceks is used to relax muscles during&nbsp;surgery&nbsp;and to help insert a trachea into the trachea and artificial respiration.&nbsp;It is also used as an aid in artificial respiration in patients undergoing intensive care.<br><\/p>\n\n\n\n<p>Atracurium besylate contained in Atracurium Kalceks may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you are given Atracurium Kalceks<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Atracurium Kalceks should not be given:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to atracurium besylate or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>If you think this may be true, talk to your doctor before taking Atracurium Kalceks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Atracurium Kalceks.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have any&nbsp;allergies&nbsp;or asthma;<\/li><li>If you have had an&nbsp;allergic reaction&nbsp;to another medicine reminiscent of Atracurium Kalceks which blocks the impulse conduction between a nerve and a muscle;<\/li><li>If you suffer from muscle weakness, fatigue, or if you have difficulty controlling your movements (&nbsp;myasthenia gravis&nbsp;);<\/li><li>If you have a neuromuscular disease;<\/li><li>If you have heart disease or are sensitive to low blood pressure;<\/li><li>If you have a severe electrolyte disturbance (unusual levels of ions such as&nbsp;sodium,&nbsp;potassium,&nbsp;or chloride in the blood)<\/li><li>If you have recently suffered severe burns that required medical attention.<\/li><\/ul>\n\n\n\n<p>If you think any of these may apply to you, talk to a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>This medicine should not be used by infants less than 1 month of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Atracurium Kalceks<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.&nbsp;This also applies to over-the-counter medicines.<br><\/p>\n\n\n\n<p>Some medicines may affect the effect of Atracurium Kalceks.&nbsp;Talk to your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anesthetics&nbsp;(used to reduce consciousness and pain during surgery), such as halothane, isoflurane, enflurane and ketamine.<\/li><li>antibiotics&nbsp;(used in the treatment of&nbsp;infections&nbsp;) eg&nbsp;aminoglycosides, polymyxins, spectinomycin,&nbsp;tetracyclines, lincomycin, and clindamycin;<\/li><li>antiarrhythmics&nbsp;(used to regulate heart rhythm) eg propranolol, oxprenolol, calcium channel blockers,&nbsp;lidocaine,&nbsp;procainamide,&nbsp;and quinidine;<\/li><li>diuretics&nbsp;(&nbsp;diuretics&nbsp;) such as&nbsp;furosemide&nbsp;, mannitol,&nbsp;thiazides,&nbsp;and acetazolamide;<\/li><li>magnesium salts (used to prevent low levels of&nbsp;magnesium&nbsp;in the body);<\/li><li>drugs used in mental illnesses such as lithium and chlorpromazine;<\/li><li>drugs used to treat high&nbsp;blood pressure&nbsp;(&nbsp;hypertension&nbsp;) such as trimethaphan and hexamethonium;<\/li><li>drugs used to treat arthritis (anti-rheumatic drugs) such as chloroquine and penicillamine;<\/li><li>drugs used in&nbsp;Alzheimer&#8217;s disease, such as donepezil;<\/li><li>steroids&nbsp;(used to treat&nbsp;inflammation&nbsp;in&nbsp;asthma&nbsp;), such as prednisolone;<\/li><li>drugs used to treat seizures (&nbsp;epilepsy&nbsp;), such as phenytoin;<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.&nbsp;Your doctor will decide if the benefits of Atracurium Kalceks outweigh the risks to your baby.<br><\/p>\n\n\n\n<p>Atracurium Kalceks can be used during a cesarean section to maintain muscle relaxation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Atracurium Kalceks has a major impact on the ability to drive and use machines.&nbsp;Consult a doctor when it is considered safe to drive and use machines again.<\/p>\n\n\n\n<p>Do not drive or use machines in case of nausea.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Atracurium Kalceks<\/h2>\n\n\n\n<p>Atracurium Kalceks is used for procedures that require you to be put under anesthesia (unconscious) or severely anesthetized.&nbsp;This medicine will always be given under the supervision of an experienced doctor.<br><\/p>\n\n\n\n<p><strong>What&nbsp;dose&nbsp;is given<\/strong><\/p>\n\n\n\n<p>Your doctor will decide which&nbsp;dose of&nbsp;Atracurium Kalceks is right for you depending on:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>your body weight;<\/li><li>how much muscle relaxation is required, and for how long;<\/li><li>your expected response to treatment with the drug;<\/li><\/ul>\n\n\n\n<p><strong>How Atracurium Kalceks is given<\/strong><\/p>\n\n\n\n<p>Atracurium Kalceks is given to you by&nbsp;injection&nbsp;directly into a vein or as a&nbsp;continuous infusion&nbsp;(usually using an infusion pump) into a vein.&nbsp;In this case, the drug is given slowly over a period of time.<br><\/p>\n\n\n\n<p>Instructions for opening the ampoule:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Turn the&nbsp;ampoule&nbsp;one by one with the colored part facing up.&nbsp;If the solution is in the upper part of the&nbsp;ampoule&nbsp;one, tap your fingers gently to bring the solution down into the lower part of the&nbsp;ampoule&nbsp;one.<\/li><li>Use both hands to open;&nbsp;while holding the lower part of the&nbsp;ampoule&nbsp;one with one hand, use the other hand to break off the upper part of the&nbsp;ampoule&nbsp;one in the direction away from the colored dot (see pictures below).<\/li><\/ol>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product;jsessionid=TfOVLe1VHt5hNFXgHBLEZ9-IKnHsL5C6nKk8OtiWhfxfkul3EV5Z!1898129783?userType=2&amp;nplId=20161129000082#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/5bcd0969-36aa-4658-81a1-a71f8d335bd3\" alt=\"Instructions for opening the ampoule\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Infants up to 1 month of age should not receive this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Atracurium Kalceks than you should<\/h2>\n\n\n\n<p>This medicine should only be given by a doctor with appropriate specialist knowledge of how to give it.&nbsp;Because this medicine is given to you when you are in hospital, it is unlikely that you will be given too much or too little medicine.&nbsp;However, always talk to a doctor or healthcare professional if you experience anxiety.&nbsp;In case you are given too large a&nbsp;dose, immediate action will be taken.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>If you experience any of the following&nbsp;side effects, talk to your doctor immediately:<\/strong><\/p>\n\n\n\n<p>Severe allergic reaction: you may experience sudden&nbsp;redness&nbsp;with&nbsp;itching&nbsp;(&nbsp;hives&nbsp;), swelling of the hands, feet, ankles, face, lips, mouth, or throat (which may cause difficulty swallowing or breathing), and you may feel dizzy.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>shock;<\/li><li>heart failure;<\/li><li>cardiac arrest;<\/li><\/ul>\n\n\n\n<p><strong>The above serious&nbsp;side effects&nbsp;are very rare.&nbsp;You may need urgent medical attention.<\/strong><\/p>\n\n\n\n<p><strong>If you experience any of the following&nbsp;side effects, tell your doctor as soon as possible:<\/strong><br><\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;), usually mild and transient;<\/li><li>reddening of the skin;<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 100)<\/p>\n\n\n\n<p>&#8211; difficulty breathing and wheezing (&nbsp;bronchospasm&nbsp;)<br><\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users)<\/p>\n\n\n\n<p>&#8211; cramps;<\/p>\n\n\n\n<p>&#8211; weak or dysfunctional muscles (&nbsp;myopathy&nbsp;);<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Atracurium Kalceks<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Store in the outer carton.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>For single use only.&nbsp;The product should be used immediately after opening.<br><\/p>\n\n\n\n<p>The appearance of the product should be inspected before use.&nbsp;Only a clear solution free of foreign particles should be used.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Atracurium Kalceks contains<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is atracurium besylate.1 ml solution contains 10 mg atracurium besylate.Each&nbsp;ampoule&nbsp;(2.5 ml) contains 25 mg of atracurium besylate.Each&nbsp;ampoule&nbsp;(5 ml) contains 50 mg of atracurium besylate.<\/li><li>The other ingredients are benzenesulfonic acid (for&nbsp;pH&nbsp;adjustment), water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What Atracurium Kalcek looks like and contents of the pack<\/h2>\n\n\n\n<p>Ready to yellowish solution for injection\/infusion, free from visible particles.<\/p>\n\n\n\n<p>2.5 ml or 5.0 ml solution filled in a 5 ml&nbsp;color I ampoule&nbsp;glass&nbsp;ampoule&nbsp;.<\/p>\n\n\n\n<p>Pack size: 1 or 5 ampoules.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>AS KALCEKS<\/p>\n\n\n\n<p>Krustpils iela 53, R\u012bga, LV \u2011 1057, Latvia<\/p>\n\n\n\n<p>Tel .: +371 67083320<\/p>\n\n\n\n<p>Email: kalceks@kalceks.lv<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"col\">Bulgaria<\/th><th scope=\"col\"><strong>Atracurium<\/strong>&nbsp;Kalceks 10 mg \/ ml Injection Injection \/ Infusion<\/th><\/tr><tr><th scope=\"col\">Czech Republic<\/th><th scope=\"col\">Atracurium Kalceks<\/th><\/tr><tr><th scope=\"col\">Estonia<\/th><th scope=\"col\">Atracurium besilate Kalceks<\/th><\/tr><tr><th scope=\"col\">France<\/th><th scope=\"col\">ATRACURIUM KALCEKS 10 mg \/ ml, injectable solution \/ for&nbsp;perfusion<\/th><\/tr><tr><th scope=\"col\">Hungary<\/th><th scope=\"col\">Atracurium besilate Kalceks 10 mg \/ ml oldatos injection \/ infusion<\/th><\/tr><tr><th scope=\"col\">Ireland<\/th><th scope=\"col\">Atracurium besilate 10 mg \/ ml solution forinjection \/ infusion<\/th><\/tr><tr><th scope=\"col\">Latvia<\/th><th scope=\"col\">Atracurium besilate Kalceks 10 mg \/ ml \u0161\u0137\u012bdums injekcij\u0101m \/ inf\u016bzij\u0101m<\/th><\/tr><tr><th scope=\"col\">Lithuania<\/th><th scope=\"col\">Atracurium besilate Kalceks 10 mg \/ ml injekcinis ar infuzinis tirpalas<\/th><\/tr><tr><th scope=\"col\">Netherlands<\/th><th scope=\"col\">Atracurium Kalceks 10 mg \/ ml solution for injection \/ infusion<\/th><\/tr><tr><th scope=\"col\">Poland<\/th><th scope=\"col\">Atracurium Kalceks<\/th><\/tr><tr><th scope=\"col\">Romania<\/th><th scope=\"col\">Atracurium Kalceks 10 mg \/ ml injectable \/ perfusible solution<\/th><\/tr><tr><th scope=\"col\">Slovakia<\/th><th scope=\"col\">Atracurium Kalceks 10 mg \/ ml injectable \/ infused solution<\/th><\/tr><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><tr><th scope=\"col\">UK<\/th><th scope=\"col\">Atracurium besilate 10 mg \/ ml solution for injection \/ infusion<\/th><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Atracurium Kalceks belongs to a group of medicines called muscle relaxants.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[9723,9726,9731,9727,9732,9725,9730,9724,9729],"class_list":["post-5717","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-atracurium-besilate","tag-atracurium-besilate-injection","tag-atracurium-kalceks-injection","tag-side-effects-of-atracurium-besilate","tag-side-effects-of-atracurium-kalceks","tag-what-atracurium-besilate-is-used-for","tag-what-atracurium-kalceks-is-used-for","tag-what-is-atracurium-besilate","tag-what-is-atracurium-kalceks"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5717"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5717\/revisions"}],"predecessor-version":[{"id":12334,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5717\/revisions\/12334"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}