{"id":5715,"date":"2020-12-24T15:04:51","date_gmt":"2020-12-24T15:04:51","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5715"},"modified":"2021-07-13T07:41:00","modified_gmt":"2021-07-13T07:41:00","slug":"atracurium-hameln","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/atracurium-hameln\/","title":{"rendered":"Atracurium Hameln &#8211; Atracurium besylate uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n10 mg \/ ml&nbsp;solution for injection&nbsp;\/&nbsp;infusion&nbsp;solution&nbsp;<br>Atracurium besylate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. WHAT THE ATRACURIUM HAMEL IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<p>Atracurium Hameln belongs to a group of medicines called muscle relaxants.&nbsp;It is used to relax muscles during&nbsp;surgery.<br><\/p>\n\n\n\n<p><strong>The Atracurium Hamel is used:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>during surgical and other procedures as well as in intensive care.<\/li><li>under anesthesia to facilitate tracheal&nbsp;intubation&nbsp;(a tube inserted into the trachea) and controlled ventilation.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. BEFORE YOU GET THE ATRACURIUM HAMEL<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use the Atracurium Hamel if:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>you are&nbsp;<strong>allergic<\/strong>&nbsp;to&nbsp;<strong>atracurium besylate<\/strong>&nbsp;or&nbsp;<strong>any of the other ingredients<\/strong>&nbsp;of this medicine (listed in section 6).&nbsp;An&nbsp;allergic reaction&nbsp;may include skin rash, difficulty breathing, or swelling of the face, lips, throat, or tongue.&nbsp;It is possible that you have experienced this before.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with the Atracurium Hamel<\/h2>\n\n\n\n<p>Before you receive the Atracurium Hamel, tell your doctor if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a disease that affects the muscles and\/or their nerve control (neuromuscular disease such as&nbsp;myasthenia gravis&nbsp;or Eaton-Lambert&#8217;s syndrome)<\/li><li>a severe electrolyte disturbance<\/li><li>cancer with the wide spread from a primary source (carcinomatosis)<\/li><li>sensitivity to&nbsp;histamine<\/li><li>asthma-like symptoms (previous&nbsp;allergy,&nbsp;asthma,&nbsp;or&nbsp;bronchospasm&nbsp;)<\/li><li>burns<\/li><li>insufficient blood volume (&nbsp;hypovolemia&nbsp;)<\/li><\/ul>\n\n\n\n<p>Children:<\/p>\n\n\n\n<p>The use of the Atracurium Hamel is not recommended for newborns (children under one month of age).&nbsp;Dose&nbsp;one must be significantly reduced in the treatment of newborns or premature babies.&nbsp;If you have any further questions, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use of other medicines<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.&nbsp;This is especially important with the following medicines as they may&nbsp;interact&nbsp;with the Atracurium hamel:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>antibiotics&nbsp;(eg&nbsp;aminoglycosides&nbsp;, polymyxins, spectinomycin,&nbsp;tetracyclines&nbsp;, lincomycin, clindamycin and vancomycin)<\/li><li>antiarrhythmics&nbsp;(used to regulate heart rhythm eg&nbsp;lidocaine&nbsp;,&nbsp;procainamide&nbsp;,&nbsp;quinidine&nbsp;)<\/li><li>diuretics&nbsp;(&nbsp;eg&nbsp;diuretics&nbsp;) (eg&nbsp;furosemide&nbsp;,&nbsp;thiazides&nbsp;, acetazolamide and mannitol)<\/li><li>medicines used to control&nbsp;blood pressure&nbsp;, angina or other heart problems (eg propranolol, oxprenolol,&nbsp;diltiazem&nbsp;, nicardipine, nifedipine and verapamil)<\/li><li>antiepileptics&nbsp;(eg carbamazepine,&nbsp;phenytoin&nbsp;)<\/li><li>medicines used to treat rheumatism (eg chloroquine, d-penicillamine)<\/li><li>corticosteroids&nbsp;are (treatment for&nbsp;inflammation&nbsp;)<\/li><li>trimethaphane, hexamethonium (used to lower&nbsp;blood pressure&nbsp;during&nbsp;surgery&nbsp;)<\/li><li>dantrolene (a muscle relaxant)<\/li><li>magnesium sulfate<\/li><li>ketamine (an anesthetic)<\/li><li>lithium, chlorpromazine (treatment for mental disorders)<\/li><li>quinine (treatment for&nbsp;malaria&nbsp;or leg cramps)<\/li><\/ul>\n\n\n\n<p>It may still be a good idea to get the Atracurium hamel and your doctor will decide what is right for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Atracurium hamel should only be given to pregnant women when it is medically justified.<\/p>\n\n\n\n<p>Mothers should stop breastfeeding for 24 hours after receiving the Atracurium hamel.&nbsp;Always consult a doctor or pharmacist before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>After receiving the Atracurium hamel, you must not drive, use machines or work in dangerous situations.&nbsp;You should not go home alone and should&nbsp;<strong>not drink alcohol&nbsp;<\/strong><strong>until you are fully recovered.<\/strong><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and \/ or&nbsp;side effects&nbsp;.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. HOW TO GET ATRACURIUM-HAMELN<\/h2>\n\n\n\n<p><strong>The atracurium Hamel should only be given by an experienced doctor under closely monitored conditions.<\/strong><br><\/p>\n\n\n\n<p><strong>Dose<\/strong><\/p>\n\n\n\n<p>The atracurium Hamel is used during procedures that require the patient to be fully anesthetized (unconscious), or given strong sedatives.<br><\/p>\n\n\n\n<p>The doctor will calculate&nbsp;the dose&nbsp;one.&nbsp;The atracurium Hamel may only be given as an&nbsp;injection&nbsp;directly into a vein (&nbsp;intravenous&nbsp;use) The atracurium Hamel may not be injected into a muscle.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<br><\/p>\n\n\n\n<p>Information for healthcare professionals is provided at the end of this information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, Atracurium Hameln can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been reported:<\/strong><\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;(affects 1 to 10 users in 100)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>tachycardia&nbsp;(high heart rate)<\/li><li>temporary&nbsp;hypotension&nbsp;(low&nbsp;blood pressure&nbsp;)<\/li><li>breathing with beeping sound<\/li><li>bronchospasm&nbsp;(asthma-like symptoms)<\/li><li>reddening of the skin<\/li><li>urticaria&nbsp;(&nbsp;hives&nbsp;)<\/li><\/ul>\n\n\n\n<p><em>Very rare<\/em>&nbsp;(affects less than 1 user in 10,000)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>myasthenia gravis&nbsp;and \/ or&nbsp;myopathy&nbsp;(weak or dysfunctional muscles)<\/li><li>severe allergic reactions including&nbsp;shock&nbsp;,&nbsp;circulatory failure&nbsp;and heart attack in patients receiving atracurium with one or more anesthetics<\/li><li>(seizures) seizures when taken concomitantly with other drugs in patients at risk<\/li><li>laryngospasm&nbsp;(&nbsp;spasm&nbsp;of the vocal cords)<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. HOW TO STORE ATRACURIUM HAMELN<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton after \u201cEXP:\u201d.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store in a refrigerator (2 \u00b0 C-8 \u00b0 C).&nbsp;Do not freeze.&nbsp;Keep the&nbsp;vial&nbsp;are in the outer carton.&nbsp;Sensitive to light.<\/li><li>The product should be used immediately after the first opening.<\/li><li>The shelf life of reconstituted solution for infusion: Chemical and physical in-use stability have been demonstrated in sodium chloride,&nbsp;BP&nbsp;infusion&nbsp;for up to 24 hours at 30 \u00b0 C and in other standard infusion fluids for up to 4 and 8 hours respectively (see dilution instructions at the end of this leaflet). The following information is intended for medical or healthcare professionals only &#8216;).&nbsp;From a&nbsp;microbiological&nbsp;point of view, the product should be used immediately.&nbsp;If the solution is not used immediately, the user is responsible for storage times after dilution and conditions before use which should not normally exceed 24 hours at 2 to 8 \u00b0 C unless dilution has taken place under controlled and verified aseptic conditions.<\/li><li>Do not use the Atracurium hammer if you notice that the solution is not clear, colorless and free of particles or if the packaging is damaged.<\/li><li>The remaining solution in opened&nbsp;ampoules&nbsp;must be discarded.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. FURTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><strong>Content declaration<\/strong><\/p>\n\n\n\n<p>The active substance is atracurium besylate.<\/p>\n\n\n\n<p>1 ml of Atracurium Hameln contains 10 mg of atracurium besylate.<\/p>\n\n\n\n<p>One&nbsp;ampoule&nbsp;of 2.5 ml&nbsp;solution for injection&nbsp;contains 25 mg of atracurium besylate.<\/p>\n\n\n\n<p>One&nbsp;ampoule&nbsp;of 5.0 ml&nbsp;solution for injection&nbsp;contains 50 mg of atracurium besylate.<\/p>\n\n\n\n<p>The other ingredients are water for injections and benzenesulfonic acid<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Atracurium Hamel is a clear and colorless solution for injection\/infusion.<br><\/p>\n\n\n\n<p>3 ml or 5 ml clear&nbsp;glass&nbsp;ampoules.<\/p>\n\n\n\n<p>Carton with 5&nbsp;ampoules&nbsp;is 2.5 ml or 5 ml.<\/p>\n\n\n\n<p>Carton of 10&nbsp;ampoules&nbsp;is 2.5 ml or 5 ml.<\/p>\n\n\n\n<p>Carton with 5 x 10&nbsp;ampoules&nbsp;is 2.5 ml or 5 ml.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>hameln pharma plus gmbh<\/p>\n\n\n\n<p>Langes Feld 13<\/p>\n\n\n\n<p>31789 Hameln<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Siegfried Hameln GmbH<\/p>\n\n\n\n<p>Langes Feld 13<\/p>\n\n\n\n<p>31789 Hameln<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p>Rotexmedica GmbH<\/p>\n\n\n\n<p>Bunsenstra\u00dfe 4<\/p>\n\n\n\n<p>22946 Trittau<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>THE:<\/td><td>Atracurium hameln 10 mg\/ml solution for injection or infusion<\/td><\/tr><tr><td>IT:<\/td><td>Atracurium-hameln 10 mg\/ml unreachable solution<\/td><\/tr><tr><td>NL:<\/td><td>Atracurium hameln 10 mg\/ml solution for injection and infusion<\/td><\/tr><tr><td>ES:<\/td><td>Besilato de Atracurio-Hameln 10 mg\/ml solution for EFG injection<\/td><\/tr><tr><td>SEE:<\/td><td>Atracurium Hameln 10 mg \/ ml solution for injection \/&nbsp;infusion&nbsp;solution<\/td><\/tr><tr><td>UK:<\/td><td>Atracurium besilate 10 mg \/ ml solution for&nbsp;injection<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Atracurium Hameln belongs to a group of medicines called muscle relaxants. It is used to relax muscles during surgery.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[9733,9736,9738,9741,9737,9742,9735,9740,9734,9739],"class_list":["post-5715","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-atracurium-besylate","tag-atracurium-besylate-injection","tag-atracurium-hameln","tag-atracurium-hameln-injection","tag-side-effects-of-atracurium-besylate","tag-side-effects-of-atracurium-hameln","tag-what-atracurium-besylate-is-used-for","tag-what-atracurium-hameln-is-used-for","tag-what-is-atracurium-besylate","tag-what-is-atracurium-hameln"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5715"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5715\/revisions"}],"predecessor-version":[{"id":12335,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5715\/revisions\/12335"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}