{"id":5436,"date":"2020-12-17T15:28:49","date_gmt":"2020-12-17T15:28:49","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5436"},"modified":"2021-07-26T07:07:20","modified_gmt":"2021-07-26T07:07:20","slug":"anastrozole-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/anastrozole-accord\/","title":{"rendered":"Anastrozole Accord &#8211; Anastrozole uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n1 mg&nbsp;film-coated tablets&nbsp;<br>anastrozole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. WHAT ANASTROZOLE ACCORD IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<p>Anastrozole Accord contains a substance called anastrozole.&nbsp;It belongs to a group of medicines called &#8220;aromatase inhibitors&#8221;.&nbsp;Anastrozole Accord is used to treat breast cancer in menopausal women.<\/p>\n\n\n\n<p>Anastrozole Accord works by reducing the amount of a&nbsp;hormone&nbsp;called&nbsp;estrogen, which is produced in the body.&nbsp;It does this by blocking a natural substance (an&nbsp;enzyme&nbsp;) in the body called &#8220;aromatase&#8221;.<\/p>\n\n\n\n<p>Anastrozole contained in the Anastrozole Accord may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. WHAT YOU NEED TO KNOW BEFORE TAKING ANASTROZOLE ACCORD<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Anastrozole Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to anastrozole or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are pregnant or breast-feeding (see section \u201cPregnancy and breast-feeding\u201d).<\/li><\/ul>\n\n\n\n<p>Do not take Anastrozole Accord if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or pharmacist before taking Anastrozole Accord.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Take special care with Anastrozole Accord<\/h2>\n\n\n\n<p><strong>Warnings and cautions<\/strong><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Anastrozole Accord:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are still menstruating and have not passed menopause.<\/li><li>have&nbsp;osteoporosis&nbsp;or other diseases that cause osteoporosis.&nbsp;<br>Anastrozole lowers the level of female sex hormone in the body and this can lead to a reduction in the mineral content of the bone structure, which in turn can make it more fragile.&nbsp;You may need to undergo a bone density test during treatment.&nbsp;Your doctor may prescribe drugs that prevent or treat osteoporosis.<\/li><li>if you are taking a medicine that contains tamoxifen or medicines that contain&nbsp;estrogen&nbsp;(see section \u201cOther medicines and Anastrozole Accord\u201d).<\/li><li>if you have ever had a condition that affects the strength of your skeleton (&nbsp;osteoporosis, ie osteoporosis).<\/li><li>if you have liver or kidney problems.<\/li><\/ul>\n\n\n\n<p><br>Talk to your doctor or pharmacist before taking Anastrozole Accord if you are not sure if any of the above apply to you.<br><\/p>\n\n\n\n<p>Tell your healthcare provider that you are taking Anastrozole Accord if you go to a hospital.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Anastrozole Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines.&nbsp;This also applies to over-the-counter medicines and herbal medicines.&nbsp;<br>This is because the Anastrozole Accord may affect the way some other medicines work, and some medicines may affect Anastrozole Accord.<\/p>\n\n\n\n<p>Do not take Anastrozole Accord if you are already taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain drugs used to treat breast cancer (selective estrogen receptor modulators), e.g.&nbsp;medicines containing tamoxifen.&nbsp;This is because these medicines can prevent the Anastrozole Accord from working properly.<\/li><li>drugs that contain&nbsp;estrogen, such as hormone replacement therapy (&nbsp;HRT&nbsp;).<\/li><\/ul>\n\n\n\n<p>Ask your doctor or pharmacist for advice if this applies to you.&nbsp;<br><\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a drug called an \u201cLHRH analog\u201d.&nbsp;These include&nbsp;gonadorelin, buserelin, goserelin, leuprorelin, and triptorelin.&nbsp;These drugs are used to treat breast cancer, certain gynecological diseases (gynecological conditions), and&nbsp;infertility.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Using Anastrozole Accord with food and drink<\/h2>\n\n\n\n<p>Using Anastrozole Accord with meals does not affect&nbsp;absorption.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children as there is not enough information about safety.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Do not take Anastrozole Accord if you are pregnant or breast-feeding.&nbsp;If you become pregnant, stop taking Anastrozole Accord and talk to a doctor.<br><\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Anastrozole Accord is unlikely to affect your ability to drive or use machines.&nbsp;However, some people may sometimes feel weak or drowsy when using Anastrozole Accord.&nbsp;Ask your doctor or pharmacist for advice if this happens to you.&nbsp;<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Anastrozole Accord contains lactose<\/h2>\n\n\n\n<p>Anastrozole Accord contains&nbsp;lactose&nbsp;which is a kind of sugar.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. HOW TO USE ANASTROZOLE ACCORD<\/h2>\n\n\n\n<p>Always take Anastrozole Accord exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is one tablet once a day.<\/li><li>The tablet should be swallowed whole with a glass of water.<\/li><li>Try to take the tablet at the same time each day.<\/li><li>It does not matter if you take the tablet before, with, or after food.<\/li><\/ul>\n\n\n\n<p>Keep taking your medicine for as long as your doctor or pharmacist tells you to.&nbsp;It is a long-term treatment and you may need to take the medicine for several years.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Use for children and adolescents<\/strong><\/p>\n\n\n\n<p>Anastrozole Accord should not be given to children and adolescents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Anastrozole Accord than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center (tel. 112) immediately for risk assessment and advice.&nbsp;Bring any leftover tablets and\/or empty packaging to facilitate identification.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Anastrozole Accord<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, just take your next&nbsp;dose&nbsp;as usual.&nbsp;Do not take a double&nbsp;dose&nbsp;(two&nbsp;doses&nbsp;at a time) to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Anastrozole Accord<\/h2>\n\n\n\n<p>Do not stop taking the tablets unless your doctor tells you to.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop taking Anastrozole Accord and seek&nbsp;emergency&nbsp;care if you experience any of the following serious but very rare side effects:<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A very severe skin reaction with sores or blisters on the skin.&nbsp;This is called &#8220;Stevens-Johnson syndrome&#8221;.<\/li><li>Allergic (hypersensitivity) reactions with swelling in the throat that may cause difficulty swallowing or breathing.&nbsp;This is called &#8220;angioedema&#8221;.<\/li><\/ul>\n\n\n\n<p><strong><em>Very common (may affect more than 1 user in 10)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hot flashes<\/li><li>Feeling weak<\/li><li>Pain or stiffness in the joints<\/li><li>Arthritis (&nbsp;arthritis&nbsp;)<\/li><li>Rash<\/li><li>Nausea<\/li><li>Headache<\/li><li>Bone tissue loss (&nbsp;osteoporosis&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong><em>Common (may affect up to 1 in 10 people)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vaginal&nbsp;dryness<\/li><li>Bleeding from&nbsp;the vagina&nbsp;(usually in the first few weeks of treatment &#8211; talk to your doctor if bleeding continues)<\/li><li>Sparser hair growth (hair loss)<\/li><li>Diarrhea<\/li><li>Loss of appetite<\/li><li>Elevated or high levels of a fatty substance called&nbsp;cholesterol&nbsp;in the blood.&nbsp;This can be seen in a blood test.<\/li><li>Nausea (vomiting)<\/li><li>Somnolence<\/li><li>Carpal tunnel syndrome&nbsp;(tingling, pain, cold, weakness in parts of the hand)<\/li><li>Tickling, tingling or numbness in the skin, loss of taste\/taste changes<\/li><li>Altered blood tests that show how your liver works<\/li><li>Skeletal pain<\/li><li>Allergic reactions (hypersensitivity) involving the face, lips, or tongue<\/li><li>Muscle pain.<\/li><\/ul>\n\n\n\n<p><strong><em>Uncommon (may affect up to 1 in 100 people)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Trigger finger (a condition in which a finger or thumb gets stuck in a bent position)<\/li><li>Changes in some blood tests that show how your liver works (gamma-GT and&nbsp;bilirubin&nbsp;)<\/li><li>Inflammation of the liver (&nbsp;hepatitis&nbsp;)<\/li><li>Hives<\/li><li>The increased amount of&nbsp;calcium&nbsp;in the blood.&nbsp;Tell your doctor, pharmacist, or nurse if you feel nauseous, vomit, or get thirsty.&nbsp;You may need to take blood samples.<\/li><\/ul>\n\n\n\n<p><strong><em>Rare (may affect up to 1 in 1,000 people)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A rare skin inflammation that can include red spots or blisters<\/li><li>Inflammation&nbsp;of the small blood vessels, which causes red or purple discoloration of the skin.&nbsp;Very rare symptoms of joint, stomach, and kidney pain may occur;&nbsp;this is called Enoch-Sch\u00f6nlein&#8217;s purple.<\/li><\/ul>\n\n\n\n<p><strong>Impact on the skeleton<\/strong><\/p>\n\n\n\n<p>Anastrozole reduces levels of&nbsp;hormone&nbsp;et&nbsp;estrogen&nbsp;in the blood, which can lead to a reduction in the mineral content of the skeletons.&nbsp;The skeleton becomes more fragile and the risk of bone fractures increases.&nbsp;Your doctor will manage these risks according to the treatment guidelines for the care of bone health in women who have passed menopause.&nbsp;Consult a physician about risks and treatment options.<br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. HOW TO STORE ANASTROZOLE ACCORD<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep out of sight and reach of children.&nbsp;Keep the tablets in a safe place where children can not see or reach them.&nbsp;The tablets may harm them.<\/li><li>No special storage instructions required.<\/li><li>Leftover medicines must always be left at the pharmacy.&nbsp;Keep it only at the doctor&#8217;s request.<\/li><li>Use Anastrozole Accord before the expiry date which is stated on the carton and blister after EXP.&nbsp;and the pressure pack at EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store the tablets in the original carton.<\/li><li>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is anastrozole.&nbsp;<br>Each film-coated tablet contains 1 mg of anastrozole.<br><\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p><em>Tablet core:&nbsp;<\/em>Lactose monohydrate&nbsp;(95, 250 mg), povidone K-30, sodium starch glycolate (type A), magnesium stearate<\/p>\n\n\n\n<p><em>Coating film:<\/em>&nbsp;Titanium dioxide (E171), macrogol 300, hypromellose E-5<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Anastrozole Accord is white to off-white, round, cupped, film-coated tablets with &#8216;AHI&#8217; embossed on the top and smooth bottom.<\/p>\n\n\n\n<p>Anastrozole Accord is supplied in blister packs of 10, 14, 20, 28, 30, 50, 56, 60, 84, 90, 98, 100 and 300 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 VK Utrecht<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>Accord Healthcare Limited<\/p>\n\n\n\n<p>Sage House, 319, Pinner Road,<\/p>\n\n\n\n<p>North Harrow, Middlesex,<\/p>\n\n\n\n<p>HA1 4 HF<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 KV Utrecht<\/p>\n\n\n\n<p>Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anastrozole Accord contains a substance called anastrozole. It belongs to a group of medicines called &#8220;aromatase inhibitors&#8221;. Anastrozole Accord is used to treat breast cancer in menopausal women.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[10091,10400,10403,10399,2212,10095,10404,10402,10093,10092,10401],"class_list":["post-5436","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-anastrozole","tag-anastrozole-accord","tag-anastrozole-accord-tablet","tag-anastrozoletablet","tag-medicine","tag-side-effects-of-anastrozole","tag-side-effects-of-anastrozole-accord","tag-what-anastrozole-accord-is-used-for","tag-what-anastrozole-is-used-for","tag-what-is-anastrozole","tag-what-is-anastrozole-accord"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5436"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5436\/revisions"}],"predecessor-version":[{"id":12624,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5436\/revisions\/12624"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}