Oral contraceptives: If you get severe diarrhea while taking this medicine, it may affect how well the oral contraceptive works, and the use of another method of contraception is recommended (eg condoms). See the instructions in the package leaflet for the contraceptive pill you are taking.<\/li><\/ul>\n\n\n\nAnagrelide or these medicines may not work properly if taken together.
<\/p>\n\n\n\n
Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Tell your doctor if you are pregnant or planning to become pregnant. Anagrelide Mylan should not be taken by pregnant women. Women who are at risk of becoming pregnant should ensure that they use effective contraception while taking anagrelide. Talk to your doctor if you need advice on contraception.<\/p>\n\n\n\n
Tell your doctor if you are breast-feeding or if you are planning to breast-feed your baby. Anagrelide Mylan should not be taken while breast-feeding. You must stop breast-feeding if you are taking Anagrelide Mylan.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Dizziness has been reported in some patients taking anagrelide. Avoid driving or using machines if you feel dizzy.<\/p>\n\n\n\n
Anagrelide Mylan contains lactose and sodium<\/h2>\n\n\n\n
This medicine contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
This medicine contains less than 1 mmol (23 mg) sodium per capsule, ie essentially ‘sodium-free’.
<\/p>\n\n\n\n
How to take Anagrelide Mylan<\/h2>\n\n\n\n
Always take Anagrelide Mylan exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n
Different people may take different amounts of anagrelide depending on the disease state. Your doctor will prescribe the dose that is best for you.
<\/p>\n\n\n\n
The usual starting dose of this medicine is 1 mg. You take this dose as a 0.5 mg capsule twice a day for at least one week. Then your doctor can either increase or decrease the number of capsules you take to find the dose that is best for you and that treats your condition most effectively.
<\/p>\n\n\n\n
The capsules should be swallowed whole and rinsed with water. They must not be crushed and the contents must not be dissolved in liquid. You can take the capsules with a meal or after a meal or on an empty stomach. You should preferably take the capsules at the same time each day.
<\/p>\n\n\n\n
Do not take<\/strong> more capsules than your doctor has recommended.
<\/p>\n\n\n\nYour doctor will take blood samples at regular intervals to check that the medicine is working effectively and that your liver and kidneys are working well.<\/p>\n\n\n\n
If you take more Anagrelide Mylan than you should<\/h2>\n\n\n\n
If you take more Anagrelide Mylan than you should, or if someone else has taken your medicine, tell your doctor or pharmacist immediately. Show them the Anagrelide Mylan pack.<\/p>\n\n\n\n
If you forget to take Anagrelide Mylan<\/h2>\n\n\n\n
Take your capsules as soon as you remember. Take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them. Talk to your doctor if you are worried.
<\/p>\n\n\n\n
Serious side effects are<\/strong><\/p>\n\n\n\nUncommon: Heart failure (signs of shortness of breath, chest pain, and leg swelling due to fluid retention), severe heart rate or heart rhythm problems ( ventricular tachycardia, supraventricular tachycardia, or atrial fibrillation ), inflammation of the pancreas causing severe pain in the stomach and back ( pancreas ) vomiting blood or black or bloody stool, severe reduction of the amount of blood s that can cause weakness, bruising, bleeding or infection s (pancytopenia), increased pressure in the artery are the lungs ( pulmonary hypertension, signs that include shortness of breath, swollen legs or ankles and that the lips and skin get a bluish tint).<\/p>\n\n\n\n
Rare: Kidney failure (little or no urination) or heart attack.
<\/p>\n\n\n\n
If you notice any of these side effects, talk to your doctor immediately.<\/strong>
<\/p>\n\n\n\nVery common side effects: may affect more than 1 in 10 people<\/strong><\/p>\n\n\n\nHeadache.
<\/p>\n\n\n\n
Common side effects: may affect up to 1 in 10 people<\/strong><\/p>\n\n\n\nDizziness, fatigue, rapid heartbeat, irregular or heavy heartbeat ( palpitation ), nausea, diarrhea, stomach pain, gas, vomiting, reduction in red blood cell count ( anemia ), fluid retention, or rash.<\/p>\n\n\n\n
Uncommon side effects: may affect up to 1 in 100 people<\/strong> <\/p>\n\n\n\nFeeling weak or sick, high blood pressure, irregular heartbeat, fainting, chills or fever, indigestion, loss of appetite, constipation, bruising, bleeding, swelling ( edema), weight loss, muscle aches, joint pain, back pain, decreased or lost sensation, especially sensation or loss of sensation abnormal sensation, or tingling and prickling, insomnia, depression, confusion, nervousness, dry mouth, memory loss, shortness of breath, nose bleeds, severe lung infection with fever, shortness of breath, cough, sputum production, hair loss, skin itching or discoloration, impotence, chest pain, decreased number of blood platelets which increases the risk of bleeding or bruising ( thrombocytopenia), fluid accumulation around the lungs or an increase in enzymes in the liver. Your doctor may do a blood test that may show an increase in the enzyme in your liver.
<\/p>\n\n\n\n
Rare side effects: may affect up to 1 in 1,000 people<\/strong><\/p>\n\n\n\nBleeding gums, weight gain, severe chest pain (angina), heart muscle disease (signs of this are fatigue, chest pain, and palpitations ), heart enlargement, fluid accumulation around the heart, painful cramps in the blood vessels of the heart (at rest, usually during the night or early morning) (Prinzmetal’s angina ), loss of coordination, difficulty speaking, dry skin, migraines, visual or double vision, ringing in the ears, dizziness when getting up from sitting or lying down, increased need to urinate at night, pain, flu-like symptoms, drowsiness, dilated blood vessels, inflammation in the colon (signs of this are diarrhea, often with blood or mucus in the stool, abdominal pain, fever), inflammation in the stomach (signs of this are pain, nausea, and vomiting), area with abnormal density in the lungs or elevated creatinine levels in the blood which may be a sign of kidney problems.
<\/p>\n\n\n\n
The following side effects have been reported but it is not known exactly how often they occur:<\/strong><\/p>\n\n\n\n- potentially life-threatening, irregular heartbeat ( Torsade de Pointes );<\/li>
- hepatitis. Signs of this are nausea, vomiting, itching, yellowing of the skin and eyes, and discoloration of feces and urine ( hepatitis );<\/li>
- pneumonia (signs of this are fever, cough, difficulty breathing, and wheezing that causes scarring of the lungs), (allergic alveolitis, including interstitial lung disease and pneumonitis );<\/li>
- renal inflammation (tubulointerstitial nephritis).<\/li><\/ul>\n\n\n\n
Reporting of side effects<\/em><\/p>\n\n\n\nIf you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n
5. How to store Anagrelide Mylan<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton and can label after EXP. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Store in the original package. Sensitive to light. Moisture sensitive. No special temperature instructions.
<\/p>\n\n\n\n
If your doctor interrupts your treatment with the medicine, you should not keep any capsules left unless your doctor tells you to. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substance is anagrelide. Each capsule contains anagrelide hydrochloride monohydrate equivalent to 0.5 mg anagrelide.
<\/p>\n\n\n\n
The other ingredients are lactose, croscarmellose sodium, povidone, microcrystalline cellulose, magnesium stearate, gelatin, and titanium dioxide (E171). See section 2 “Anagrelide Mylan contains lactose and sodium”.<\/p>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Anagrelide Mylan 0.5 mg hard capsules have a white bottom and top. The capsule contains white or almost white powder.<\/p>\n\n\n\n
The dimensions of the capsule are approximately 14.3 x 5.3 mm.<\/p>\n\n\n\n
Anagrelide Mylan is supplied in 30 ml or 75 ml plastic jars with desiccant and a safety-sealed, child-resistant lid. Each jar contains 100 hard capsules.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Mylan SAS<\/p>\n\n\n\n
117 All\u00e9e des Parcs<\/p>\n\n\n\n
Saint-Priest<\/p>\n\n\n\n
69800, France
<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nSynthon Hispania SL<\/p>\n\n\n\n
C \/ Castell\u00f3 no1<\/p>\n\n\n\n
TERMINAL. Las Salinas<\/p>\n\n\n\n
Sant Boi de Llobregat<\/p>\n\n\n\n
08830 Barcelona<\/p>\n\n\n\n
Spain
<\/p>\n\n\n\n
Synthon BV<\/p>\n\n\n\n
Microweg 22<\/p>\n\n\n\n
6545 CM Nijmegen<\/p>\n\n\n\n
Netherlands
<\/p>\n\n\n\n
Contact the representative of the marketing authorization holder to find out more about this medicine:
<\/p>\n","protected":false},"excerpt":{"rendered":"
Anagrelide Mylan contains the active substance anagrelide. Anagrelide is a drug that affects the development of platelets. It reduces the number of platelets produced by the bone marrow and thus the number of platelets in the blood becomes more normal. Therefore, it is used to treat patients with essential thrombocytopenia.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[10420,10442,10445,2239,10424,10446,10422,10444,10430,10443],"class_list":["post-5424","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-anagrelide","tag-anagrelide-mylan","tag-anagrelide-mylan-capsule","tag-capsule","tag-side-effects-of-anagrelide","tag-side-effects-of-anagrelide-mylan","tag-what-anagrelide-is-used-for","tag-what-anagrelide-mylan-is-used-for","tag-what-is-anagrelide","tag-what-is-anagrelide-mylan"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5424","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5424"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5424\/revisions"}],"predecessor-version":[{"id":12651,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5424\/revisions\/12651"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}