940 mg \/ g granules
Sodium phenylbutyrate <\/p>\n\n\n\n
500 mg tablets
Sodium phenylbutyrate <\/p>\n\n\n\n
AMMONAPS is prescribed to patients with urea metabolic disorders. Patients suffering from these unusual disorders are deficient in certain liver enzymes and therefore cannot excrete nitrogen residues. Nitrogen is a building block in protein and therefore nitrogen accumulates in the body when you have eaten protein. Nitrogen residues in the form of ammonia are especially toxic to the brain and in severe cases lead to decreased consciousness and coma.<\/p>\n\n\n\n
AMMONAPS helps the body excrete nitrogen residues, and reduces the amount of ammonia in your body.
<\/p>\n\n\n\n
Talk to your doctor before taking AMMONAPS<\/p>\n\n\n\n
AMMONAPS should be combined with a diet, which is protein-reduced and which is individually adapted for you by the doctor or dietitian. This diet must be followed carefully.
<\/p>\n\n\n\n
AMMONAPS does not completely prevent an acute excess of ammonia in the blood<\/p>\n\n\n\n
arises and is not suitable for the treatment of such a condition, which is considered an acute medical condition.
<\/p>\n\n\n\n
If you need to do laboratory tests, it is important to remind your doctor that you are taking AMMONAPS, as sodium phenylbutyrate may affect the results of some laboratory tests.<\/p>\n\n\n\n
Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
It is especially important that you tell your doctor if you are taking medicines that contain:<\/p>\n\n\n\n
These medicines may affect the way AMMONAPS works and you may need to do more frequent blood tests. If you are not sure if your medicines contain these substances, ask your doctor or pharmacist.<\/p>\n\n\n\n
Do not use AMMONAPS if you are pregnant, as this medicine may harm the fetus. If you are a woman who may become pregnant, you must use a reliable contraceptive during treatment with AMMONAPS.<\/p>\n\n\n\n
Do not use AMMONAPS if you are breast-feeding, as this medicine may pass into breast milk and harm your baby.<\/p>\n\n\n\n
No studies on the effects on the ability to drive and use machines have been performed.<\/p>\n\n\n\n
A small white spoon of AMMONAPS granules contains 149 mg of sodium.<\/p>\n\n\n\n
A medium-sized yellow spoon of AMMONAPS granules contains 408 mg of sodium.<\/p>\n\n\n\n
A large blue spoon of AMMONAPS granules contains 1200 mg of sodium.<\/p>\n\n\n\n
Talk to your doctor or pharmacist if you need to take 2 or more of the small white spoon or 1 or more medium yellow or large blue spoon daily for an extended period of time, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
Dosage<\/strong><\/p>\n\n\n\n The daily dose of one of AMMONAPS is calculated based on your ability to tolerate protein, diet, and body weight or body surface area. You will need regular blood tests to determine the correct daily dosage. Your doctor will tell you how much granules take.<\/p>\n\n\n\n Method of administration<\/strong><\/p>\n\n\n\n AMMONAPS should be taken in equal doses by mouth, through a gastrostomy (gastric fistula, a tube that passes through the abdominal wall to the stomach), or through a gastric tube (a tube that passes through the nose to the stomach).<\/p>\n\n\n\n AMMONAPS must be taken with a special protein-reduced diet.<\/p>\n\n\n\n You should take AMMONAPS at every meal or feeding. In young children, this can be 4 to 6 times a day.<\/p>\n\n\n\n To measure the dose:<\/p>\n\n\n\n Ingestion by mouth<\/em><\/p>\n\n\n\n Mix the measured dose with solid food (such as mashed potatoes or apple puree) or liquid food (such as water, apple juice, orange juice, or protein-free infant drink) to be taken immediately after mixing. Patients with gastrostomy (gastric fistula) or gastric tube<\/em><\/p>\n\n\n\n Mix the granules with water until there are no dry granules left (by stirring in the solution, the granules can be more easily dissolved). When the granules have been dissolved in water, a milky white solution is obtained. Take the solution immediately after mixing.<\/p>\n\n\n\n You need to receive treatment and diet for the rest of your life if you do not undergo a successful liver transplant.<\/p>\n\n\n\n Patients who have taken very high doses of AMMONAPS experienced:<\/p>\n\n\n\n If you experience any of these symptoms, contact your doctor or nearest emergency department immediately for supportive care.<\/p>\n\n\n\n Take the next dose as soon as possible at the next meal. Make sure there are at least 3 hours between two doses. Do not take a double dose to make up for a forgotten dose.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n The frequency of possible side effects is listed below. Very common side effects:<\/em> irregular periods or missed periods. If you are sexually active and your period stops completely, do not take it for granted that this has been caused by AMMONAPS. If this happens, you should discuss it with your doctor, as missed periods can also be due to pregnancy (see the section on pregnancy and breastfeeding above).<\/p>\n\n\n\n Common side effects:<\/em> altered blood cell count ( red blood cells, white blood cells, and platelets ), decreased appetite, depression, irritability, headache, fainting, fluid retention (swelling), taste changes, abdominal pain, vomiting, nausea, constipation, skin odor, rash, abnormal kidney function weight gain, altered laboratory test values.<\/p>\n\n\n\n Uncommon side effects:<\/em> lack of red blood cells due to bone marrow depression, bruising, altered heart rhythm, rectal bleeding, stomach irritation, stomach ulcer, inflammation of the pancreas.<\/p>\n\n\n\n If repeated vomiting occurs, contact your doctor immediately. Reporting of side effects<\/em><\/p>\n\n\n\n If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and bottle label after \u201cEXP\u201d. The expiration date is the last day of the specified month. Do not store above 25 \u00b0 C. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n AMMONAPS granules are off-white. Granules are packed in plastic bottles with childproof lids. Each bottle contains 266 g or 532 g of granules. Three spoons (a small white spoon, a medium-sized yellow spoon, and a large blue spoon) are included for measuring the daily dose.<\/p>\n\n\n\n Immedica Pharma AB<\/p>\n\n\n\n SE-113 29 Stockholm<\/p>\n\n\n\n Manufacturer<\/strong><\/p>\n\n\n\n PATHEON France – BOURGOIN JALLIEU<\/p>\n\n\n\n 40 Boulevard de Champaret<\/p>\n\n\n\n BOURGOIN JALLIEU<\/p>\n\n\n\n 38300<\/p>\n\n\n\n France<\/p>\n","protected":false},"excerpt":{"rendered":" AMMONAPS is prescribed to patients with urea metabolic disorders. Patients suffering from these unusual disorders are deficient in certain liver enzymes and therefore cannot excrete nitrogen residues. Nitrogen is a building block in protein and therefore nitrogen accumulates in the body when you have eaten protein. Nitrogen residues in the form of ammonia are especially toxic to the brain and in severe cases lead to decreased consciousness and coma.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[10555,10558,10559,10554,10550,10553,10557,10556,10551,10552],"class_list":["post-5374","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-ammonaps","tag-ammonaps-tablet","tag-side-effects-of-ammonaps","tag-side-effects-of-sodium-phenylbutyrate","tag-sodium-phenylbutyrate","tag-sodium-phenylbutyrate-tablet","tag-what-ammonaps-is-used-for","tag-what-is-ammonaps","tag-what-is-sodium-phenylbutyrate","tag-what-sodium-phenylbutyrate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5374","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5374"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5374\/revisions"}],"predecessor-version":[{"id":12711,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5374\/revisions\/12711"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5374"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5374"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/p>\n\n\n\nIf you take more AMMONAPS than you should<\/h2>\n\n\n\n
If you forget to take AMMONAPS<\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
<\/p>\n\n\n\nVery common:<\/td> Affects more than 1 in 10 users<\/td><\/tr> Usual:<\/td> Affects 1 to 10 users out of 100<\/td><\/tr> Uncommon:<\/td> Affects 1 to 10 users out of 1000<\/td><\/tr> Rare:<\/td> Affects 1 to 10 users out of 10,000<\/td><\/tr> Very rare:<\/td> Affects less than 1 in 10,000 users<\/td><\/tr> No known frequency:<\/td> The frequency cannot be calculated from the available data<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
<\/p>\n\n\n\n5. How to store AMMONAPS<\/h2>\n\n\n\n
<\/p>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
<\/p>\n\n\n\nMarketing Authorisation Holder<\/h2>\n\n\n\n
<\/p>\n\n\n\n