\n\n75 mg \/ 1.5 mL concentrate and diluent to concentrate for infusion solution
amsacrine<\/p>\n\n\n\n
Amekrin belongs to a group of medicines called cytostatics (medicines used to treat cancer).<\/p>\n\n\n\n
It is used to treat acute myeloid leukemia, also called AML. AML is a type of blood and bone marrow cancer.<\/p>\n\n\n\n
Amekrin is used in adults when the disease has not responded to other treatments or in relapses.<\/p>\n\n\n\n
Amsakrin contained in Amekrin may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.
<\/p>\n\n\n\n
Talk to your doctor before using this medicine if any of the above apply to you.<\/p>\n\n\n\n
Talk to your doctor, pharmacist, or nurse before you are treated with Amekrin.<\/p>\n\n\n\n
Your doctor will be especially careful if any of the following apply to you.<\/p>\n\n\n\n
Talk to your doctor before using this medicine if any of the above apply to you.<\/p>\n\n\n\n
Amekrin should only be used by adults. Amekrin should not be used by children and adolescents under 18 years of age.
<\/p>\n\n\n\n
Regular examinations<\/strong><\/p>\n\n\n\n Your doctor will perform regular medical examinations, e.g. blood tests to check the number of blood cells and kidney and liver function as well as examinations of the heart.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n A large number of drugs can interact with Amekrin and have markedly altered effects. Some examples:<\/p>\n\n\n\n If you are already taking any of these medicines, talk to your doctor before receiving Amekrin.<\/p>\n\n\n\n If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Pregnancy<\/strong><\/p>\n\n\n\n During pregnancy, this medicine should only be given if absolutely necessary. The benefits of treatment must be weighed against the risk to your unborn child. Precautions regarding pregnancy for men and women<\/strong><\/p>\n\n\n\n Women of childbearing potential must use effective contraception during and up to three months after stopping treatment. Men must use effective contraceptive during and up to six months after stopping treatment. Breast-feeding<\/strong><\/p>\n\n\n\n Do not breast-feed while receiving Amekrin. Fertility<\/strong><\/p>\n\n\n\n There is some evidence to suggest that amsacrine has a negative effect on female fertility. Some evidence suggests that male fertility may be temporarily adversely affected.<\/p>\n\n\n\n Amekrin is unlikely to affect your ability to drive or use machines. If you experience side effects such as headache and dizziness after the infusion has been given to you, be careful when driving or using machines.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n <\/p>\n\n\n\n You will normally be given Amekrin in a hospital by a doctor or nurse who has experience in the use of chemotherapy.<\/p>\n\n\n\n Amekrin is injected slowly as an infusion into a vein for 1-2 hours.<\/p>\n\n\n\n Dose one is calculated by your doctor based on your age and body surface area (normally 300-650 mg per square meter per treatment period). Initial treatment<\/strong><\/p>\n\n\n\n You will receive one infusion per day for 3-7 days. Further treatment<\/strong><\/p>\n\n\n\n After the initial treatment period, additional doses are given depending on the number of blood cells in your blood.<\/p>\n\n\n\n If Amekrin reduces the number of blood cells too much, your doctor may need to give you a blood transfusion.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n Because infusion one will be given under the supervision of a doctor, it is unlikely that you will receive more than necessary. Talk to your doctor if you are worried about dosing one of the medicines. If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. All medicines can cause allergic reactions, although severe allergic reactions are rare. Sudden wheezing, difficulty breathing, swelling of the eyelids, face or lips, rash or itching (especially if the rash or itching affects the whole body) should be reported to a doctor immediately.<\/strong> Very common (may affect more than 1 user in 10)<\/em><\/strong><\/p>\n\n\n\n Common (may affect up to 1 in 10 people)<\/em><\/strong><\/p>\n\n\n\n Rare (may affect up to 1 in 1,000 people):<\/em><\/strong><\/p>\n\n\n\n No known frequency (cannot be calculated from the available data)<\/em><\/strong><\/p>\n\n\n\n The above list of possible side effects may seem daunting, but acute leukemia is a serious illness that requires aggressive treatment. Reporting of side effects<\/em><\/p>\n\n\n\n If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not store above 25 \u00b0 C.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Amekrin delivered in sets of one vial of clear glass with a concentrate and a vial of clear glass with liquid. The concentrate vial contains the active substance amsacrine and N, N-dimethylacetamide in 1.5 ml clear orange \/ red liquid.<\/p>\n\n\n\n The vial of liquid contains 13.5 ml solution of lactic acid in water for injections as a clear solution. Pack size<\/p>\n\n\n\n 1 x 6 vials of concentrate for solution for infusion and 6 vials of liquid for solution for infusion.<\/p>\n\n\n\n Eurocept International BV<\/p>\n\n\n\n Trapgans 5<\/p>\n\n\n\n 1244 RL Ankeveen<\/p>\n\n\n\n Netherlands This medicinal product is authorized under the European Economic Area under the names:<\/strong> Amekrin belongs to a group of medicines called cytostatics (medicines used to treat cancer).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[10675,10679,10670,10673,10678,10674,10677,10672,10676,10671],"class_list":["post-5317","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-amekrin","tag-amekrin-injection","tag-amsacrine","tag-amsacrine-injection","tag-side-effects-of-amekrin","tag-side-effects-of-amsacrine","tag-what-amekrin-is-used-for","tag-what-amsacrine-is-used-for","tag-what-is-amekrin","tag-what-is-amsacrine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5317","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5317"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5317\/revisions"}],"predecessor-version":[{"id":12757,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5317\/revisions\/12757"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5317"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5317"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Other drugs and Amekrin<\/h2>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
3. How to use Amekrin<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nIf you use more Amekrin than you should <\/h2>\n\n\n\n
<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n5. How to store Amekrin<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content Declaration for Amekrin<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nName of Member State<\/strong><\/td> Name of the medicine<\/strong><\/td><\/tr><\/thead> Austria<\/td> Amsidyl 75 mg \/ 1.5 ml concentrate and solvent for concentrate for solution for infusion<\/td><\/tr> Belgium<\/td> Amsidine 75 mg \/ 1.5 ml concentrate and solvent for solution for infusion<\/td><\/tr> Czech Republic<\/td> Amsidyl 75 mg \/ 1.5 ml ml concentrate and rosemary concentrate for infused rosemary<\/td><\/tr> Denmark<\/td> Amekrin 75 mg \/ 1.5 ml concentrate and solvent for concentrate for solution for infusion <\/td><\/tr> Finland<\/td> Amekrin 75 mg \/ 1.5 ml infusioconcentrate and liuotin, infusion concentrate liuosta varten<\/td><\/tr> Germany<\/td> Amsidyl 75 mg concentrate for the preparation of an infusion solution<\/td><\/tr> Iceland<\/td> Amekrin 75 mg \/ 1.5 ml Concentrate and solvent for concentrate for solution for infusion<\/td><\/tr> Ireland<\/td> Amsidine concentrate and solvent for solution for infusion 50 mg\/ml<\/td><\/tr> Italy<\/td> Amsadina 75 mg \/ 1.5 ml concentrate and solvent per concentrate per solution per infusion<\/td><\/tr> Luxembourg<\/td> Amsidine 75 mg \/ 1.5 ml diluted and solvent solution for perfusion<\/td><\/tr> Malta<\/td> Amsidine Concentrate in Solvent Gel Solutions 50 mg \/ ml Infusion<\/td><\/tr> Netherlands<\/td> Amsidine concentrate and solvent for solution for infusion 75 mg \/ 1.5 ml<\/td><\/tr> Norway<\/td> Amekrin 75 mg \/ 1.5 ml concentrate and liquid for concentrate for solution for infusion<\/td><\/tr> Poland<\/td> Amsidyl 75 mg \/ 1.5 ml concentrate and concentrate for concentrates and infusion preparations<\/td><\/tr> Portugal<\/td> Amekrin 75 mg \/ 1.5 ml concentrate and solvent for concentration for perfusion<\/td><\/tr> Slovakia<\/td> Amsidyl 75 mg \/ 1.5 ml concentrate and suspension for infusion concentrate<\/td><\/tr> Spain<\/td> Amekrin 75 mg \/ 1.5 ml concentrate and solvent for solution for perfusion<\/td><\/tr> <\/td> <\/td><\/tr> UK<\/td> Amsidine concentrate and solvent for solution for infusion 50 mg \/ ml<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"